Distribution of lymphocyte subpopulations in thyroid glands of human autoimmune thyroid disease

Journal of Clinical Laboratory Analysis

Volumn 28, Issue 3, 2014, Pages 249-254

  Zha, Bingbing ^a   Huang, Xiuyan ^b   Lin, Jun ^b   Liu, Jun ^a   Hou, Yingyong ^a   Wu, Guilong ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

CD20; CD4; CD8; FoxP3; Graves' disease; Hashimoto's thyroiditis; Regulatory T cells

Indexed keywords

PROPYLTHIOURACIL; THIAMAZOLE; THYROID HORMONE; TRANSCRIPTION FACTOR FOXP3;

ARTICLE; B LYMPHOCYTE; CD20+ B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPH FOLLICLE; LYMPHOCYTE SUBPOPULATION; LYMPHOCYTIC INFILTRATION; MAJOR CLINICAL STUDY; PARATHYROIDECTOMY; REGULATORY T LYMPHOCYTE; THYROID FOLLICLE; THYROID GLAND; IMMUNOLOGY;

CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; GRAVES DISEASE; HASHIMOTO DISEASE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; THYROID GLAND;

EID: 84899622470     PISSN: 08878013     EISSN: 10982825     Source Type: Journal    
DOI: 10.1002/jcla.21674     Document Type: Article

References (17)

1. Weetman AP. Autoimmune thyroid disease: Propagation and progression. Eur J Endocrinol 2003;148:1-9.
2. Sepulveda H, Cerwenka A, Morgan T, Dutton RW. CD28, IL-2-independent costimulatory pathways for CD8 T lymphocyte activation. J Immunol 1999;163:1133-1142.
3. Miyara M, Sakaguchi S. Natural regulatory T cells: Mechanisms of suppression. Trends Mol Med 2007;13:108-116.
4. Baecher-Allan C, Viglietta V, Hafler DA. Human CD4+CD25+ regulatory T cells. Semin Immunol 2004;16:89-98.
5. Banham AH, Powrie FM, Suri-Payer E. FOXP3+ regulatory T cells: Current controversies and future perspectives. Eur J Immunol 2006;36:2832-2836.
6. Lee OJ, Hong SM, Razvi MH, et al. Expression of calcium-binding proteins S100A2 and S100A4 in Barrett's adenocarcinomas. Neoplasia 2006;8:843-850.
7. Pan D, Shin YH, Gopalakrishnan G, Hennessey J, De Groot LJ. Regulatory T cells in Graves' disease. Clin Endocrinol (Oxf) 2009;71:587-593.
8. Marazuela M, García-López MA, Figueroa-Vega N, et al. Regulatory T-cells in human autoimmune thyroid disease. J Clin Endocrinol Metab 2006;91:3639-3646.
9. Ben-Skowronek I, Sierocinska-Sawa J, Szewczyk L, Korobowicz E. Interaction of lymphocytes and thyrocytes in Graves' disease and nonautoimmune thyroid diseases in immunohistochemical and ultrastructural investigations. Horm Res 2009;71:350-358.
10. Weetman AP. The immunomodulatory effects of antithyroid drugs. Thyroid 1994;4:145-146.
11. Nakamura Y, Watanabe M, Matsuzuka F, et al. Intrathyroidal CD4+ T lymphocytes express high levels of Fas and CD4+ CD8+ macrophages/dendritic cells express Fas ligand in autoimmune thyroid disease. Thyroid 2004;14:819-824.
12. El Fassi D, Clemmensen O, Nielsen CH, Silkiss RZ, Hegedüs L. Evidence of intrathyroidal B-lymphocyte depletion after rituximab therapy in a patient with Graves' disease. J Clin Endocrinol Metab 2007;92:3762-3763.
13. Segundo C, Rodríguez C, Aguilar M, et al. Differences in thyroid-infiltrating B lymphocytes in patients with Graves' disease: Relationship to autoantibody detection. Thyroid 2004;14:337-344.
14. El Fassi D, Nielsen CH, Hasselbalch HC, Hegedüs L. The rationale for B lymphocyte depletion in Graves' disease. Monoclonal anti-CD20 antibody therapy as a novel treatment option. Eur J Endocrinol 2006;154:623-632.
15. El Fassi D, Nielsen CH, Bonnema SJ, Hasselbalch HC, Hegedüs L. B lymphocyte depletion with the monoclonal antibody rituximab in Graves' disease: A controlled pilot study. J Clin Endocrinol Metab 2007;92:1769-1772.
16. Kahara T, Iwaki N, Kaya H, et al. Transition of thyroid autoantibodies by rituximab treatment for thyroid MALT lymphoma. Endocr J 2011;58:7-12.
17. Penna G, Roncari A, Amuchastegui S, et a1. Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1, 25-dihydroxyvitamin D3. Blood 2005;106:3490-3497.