PKC-mediated potentiation of morphine analgesia by St. John's wort in rodents and humans

Journal of Pharmacological Sciences

Volumn 124, Issue 4, 2014, Pages 409-417

  Galeotti, Nicoletta ^a   Farzad, Mersedeh ^b   Bianchi, Enrica ^c   Ghelardini, Carla ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Oncology Department CORAT ASL7   (Italy)

^c UNIVERSITY OF SIENA   (Italy)

Author keywords

Morphine; Protein kinase C; St. John's wort; Thermal nociception

Indexed keywords

AMENTOFLAVONE; CALPHOSTIN C; HYPERFORIN; HYPERICIN; HYPERICUM PERFORATUM EXTRACT; HYPERIN; MORPHINE; MORPHINE SULFATE; PROTEIN KINASE C; QUERCETIN; QUIENS; UNCLASSIFIED DRUG;

ADULT; ANALGESIA; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENTIATION; DRUG TOLERANCE; ENZYME PHOSPHORYLATION; HEAT; HUMAN; HUMAN EXPERIMENT; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; NORMAL HUMAN; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; PERIAQUEDUCTAL GRAY MATTER; RAT;

ADMINISTRATION, ORAL; ANALGESIA; ANALGESICS, OPIOID; ANIMALS; DRUG SYNERGISM; ENZYME INHIBITORS; HOT TEMPERATURE; HUMANS; HYPERICUM; MALE; MICE; MORPHINE; NOCICEPTION; PAIN MEASUREMENT; PERIAQUEDUCTAL GRAY; PERYLENE; PHOSPHORYLATION; PLANT EXTRACTS; PROTEIN KINASE C;

EID: 84899556530     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.13226FP     Document Type: Article

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