-
1
-
-
84868193217
-
Innate immunosenescence: Effect of aging on cells and receptors of the innate immune system in humans
-
Solana R, Tarazona R, Gayoso I, Lesur O, Dupuis G, et al. (2012) Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans. Semin Immunol 24: 331-341.
-
(2012)
Semin Immunol
, vol.24
, pp. 331-341
-
-
Solana, R.1
Tarazona, R.2
Gayoso, I.3
Lesur, O.4
Dupuis, G.5
-
2
-
-
0032101961
-
Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses
-
Desmedt M, Rottiers P, Dooms H, Fiers W, Grooten J (1998) Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses. J Immunol 160: 5300-5308. (Pubitemid 28267817)
-
(1998)
Journal of Immunology
, vol.160
, Issue.11
, pp. 5300-5308
-
-
Desmedt, M.1
Rottiers, P.2
Dooms, H.3
Fiers, W.4
Grooten, J.5
-
3
-
-
84876775203
-
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes
-
Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, et al. (2013) Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 38: 792-804.
-
(2013)
Immunity
, vol.38
, pp. 792-804
-
-
Hashimoto, D.1
Chow, A.2
Noizat, C.3
Teo, P.4
Beasley, M.B.5
-
4
-
-
2342537773
-
From Blood Monocytes to Adipose Tissue-Resident Macrophages: Induction of Diapedesis by Human Mature Adipocytes
-
DOI 10.2337/diabetes.53.5.1285
-
Curat CA, Miranville A, Sengenes C, Diehl M, Tonus C, et al. (2004) From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes. Diabetes 53: 1285-1292. (Pubitemid 38569015)
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1285-1292
-
-
Curat, C.A.1
Miranville, A.2
Sengenes, C.3
Diehl, M.4
Tonus, C.5
Busse, R.6
Bouloumie, A.7
-
5
-
-
34347354309
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
-
DOI 10.1038/nature05894, PII NATURE05894
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, et al. (2007) Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature 447: 1116-1120. (Pubitemid 47014427)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Eagle, A.R.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
7
-
-
0037378533
-
+-T-cell effector function and migration following viral infection
-
DOI 10.1128/JVI.77.7.4004-4014.2003
-
Trifilo MJ, Bergmann CC, Kuziel WA, Lane TE (2003) CC chemokine ligand 3 (CCL3) regulates CD8(+) -T-cell effector function and migration following viral infection. J Virol 77: 4004-4014. (Pubitemid 36350941)
-
(2003)
Journal of Virology
, vol.77
, Issue.7
, pp. 4004-4014
-
-
Trifilo, M.J.1
Bergmann, C.C.2
Kuziel, W.A.3
Lane, T.E.4
-
8
-
-
84876800337
-
Macrophage biology in development, homeostasis and disease
-
Wynn TA, Chawla A, Pollard JW (2013) Macrophage biology in development, homeostasis and disease. Nature 496: 445-455.
-
(2013)
Nature
, vol.496
, pp. 445-455
-
-
Wynn, T.A.1
Chawla, A.2
Pollard, J.W.3
-
9
-
-
84855171780
-
PI3K functions in cancer progression, anticancer immunity and immune evasion by tumors
-
Dituri F, Mazzocca A, Giannelli G, Antonaci S (2011) PI3K functions in cancer progression, anticancer immunity and immune evasion by tumors. Clin Dev Immunol 2011: 947858.
-
(2011)
Clin Dev Immunol
, vol.2011
, pp. 947858
-
-
Dituri, F.1
Mazzocca, A.2
Giannelli, G.3
Antonaci, S.4
-
10
-
-
84856367507
-
Immunology in clinic review series; focus on autoinflammatory diseases: Update on monogenic autoinflammatory diseases: The role of interleukin (IL)-1 and an emerging role for cytokines beyond IL-1
-
Goldbach-Mansky R (2012) Immunology in clinic review series; focus on autoinflammatory diseases: update on monogenic autoinflammatory diseases: the role of interleukin (IL)-1 and an emerging role for cytokines beyond IL-1. Clin Exp Immunol 167: 391-404.
-
(2012)
Clin Exp Immunol
, vol.167
, pp. 391-404
-
-
Goldbach-Mansky, R.1
-
11
-
-
84855173084
-
Inflammatory cytokines in systemic lupus erythematosus
-
Ohl K, Tenbrock K (2011) Inflammatory cytokines in systemic lupus erythematosus. J Biomed Biotechnol 2011: 432595.
-
(2011)
J Biomed Biotechnol
, vol.2011
, pp. 432595
-
-
Ohl, K.1
Tenbrock, K.2
-
13
-
-
79959438318
-
Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis
-
McGillicuddy FC, Harford KA, Reynolds CM, Oliver E, Claessens M, et al. (2011) Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis. Diabetes 60: 1688-1698.
-
(2011)
Diabetes
, vol.60
, pp. 1688-1698
-
-
McGillicuddy, F.C.1
Harford, K.A.2
Reynolds, C.M.3
Oliver, E.4
Claessens, M.5
-
14
-
-
79952451443
-
Obesity, insulin resistance and free fatty acids
-
Boden G (2011) Obesity, insulin resistance and free fatty acids. Curr Opin Endocrinol Diabetes Obes 18: 139-143.
-
(2011)
Curr Opin Endocrinol Diabetes Obes
, vol.18
, pp. 139-143
-
-
Boden, G.1
-
15
-
-
0023665111
-
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity
-
Kaplan DR, Whitman M, Schaffhausen B, Pallas DC, White M, et al. (1987) Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell 50: 1021-1029.
-
(1987)
Cell
, vol.50
, pp. 1021-1029
-
-
Kaplan, D.R.1
Whitman, M.2
Schaffhausen, B.3
Pallas, D.C.4
White, M.5
-
16
-
-
0021828496
-
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
-
DOI 10.1038/315239a0
-
Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM (1985) Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature 315: 239-242. (Pubitemid 15064453)
-
(1985)
Nature
, vol.315
, Issue.6016
, pp. 239-242
-
-
Whitman, M.1
Kaplan, D.R.2
Schaffhausen, B.3
-
17
-
-
43749120732
-
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications
-
DOI 10.2174/156800908784293659
-
Carnero A, Blanco-Aparicio C, Renner O, Link W, Leal JF (2008) The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications. Curr Cancer Drug Targets 8: 187-198. (Pubitemid 351688437)
-
(2008)
Current Cancer Drug Targets
, vol.8
, Issue.3
, pp. 187-198
-
-
Carnero, A.1
Blanco-Aparicio, C.2
Renner, O.3
Link, W.4
Leal, J.F.M.5
-
18
-
-
1642617693
-
PI3K/Akt signalling pathway and cancer
-
Fresno Vara JA, Casado E, de Castro J, Cejas P, Belda-Iniesta C, et al. (2004) PI3K/Akt signalling pathway and cancer. Cancer Treat Rev 30: 193-204.
-
(2004)
Cancer Treat Rev
, vol.30
, pp. 193-204
-
-
Fresno Vara, J.A.1
Casado, E.2
De Castro, J.3
Cejas, P.4
Belda-Iniesta, C.5
-
19
-
-
0037439632
-
Phosphoinositide-3-kinase-independent contractile activities associated with Fcgamma-receptor-mediated phagocytosis and macropinocytosis in macrophages
-
DOI 10.1242/jcs.00235
-
Araki N, Hatae T, Furukawa A, Swanson JA (2003) Phosphoinositide-3- kinase-independent contractile activities associated with Fcgamma-receptor- mediated phagocytosis and macropinocytosis in macrophages. J Cell Sci 116: 247-257. (Pubitemid 36163866)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.2
, pp. 247-257
-
-
Araki, N.1
Hatae, T.2
Furukawa, A.3
Swanson, J.A.4
-
20
-
-
79957563749
-
A class IA PI3K controls inflammatory cytokine production in human neutrophils
-
Fortin CF, Cloutier A, Ear T, Sylvain-Prevost S, Mayer TZ, et al. (2011) A class IA PI3K controls inflammatory cytokine production in human neutrophils. Eur J Immunol 41: 1709-1719.
-
(2011)
Eur J Immunol
, vol.41
, pp. 1709-1719
-
-
Fortin, C.F.1
Cloutier, A.2
Ear, T.3
Sylvain-Prevost, S.4
Mayer, T.Z.5
-
21
-
-
77950457187
-
PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans
-
Soond DR, Bjorgo E, Moltu K, Dale VQ, Patton DT, et al. (2010) PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans. Blood 115: 2203-2213.
-
(2010)
Blood
, vol.115
, pp. 2203-2213
-
-
Soond, D.R.1
Bjorgo, E.2
Moltu, K.3
Dale, V.Q.4
Patton, D.T.5
-
22
-
-
84860329496
-
Cep70 contributes to angiogenesis by modulating microtubule rearrangement and stimulating cell polarization and migration
-
Shi X, Liu M, Li D, Wang J, Aneja R, et al. (2012) Cep70 contributes to angiogenesis by modulating microtubule rearrangement and stimulating cell polarization and migration. Cell Cycle 11: 1554-1563.
-
(2012)
Cell Cycle
, vol.11
, pp. 1554-1563
-
-
Shi, X.1
Liu, M.2
Li, D.3
Wang, J.4
Aneja, R.5
-
23
-
-
79953219078
-
Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner
-
Li D, Xie S, Ren Y, Huo L, Gao J, et al. (2011) Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner. Protein Cell 2: 150-160.
-
(2011)
Protein Cell
, vol.2
, pp. 150-160
-
-
Li, D.1
Xie, S.2
Ren, Y.3
Huo, L.4
Gao, J.5
-
24
-
-
33646706052
-
Oncogenic PI3K and its role in cancer
-
DOI 10.1097/01.cco.0000198021.99347.b9, PII 0000162220060100000013
-
Samuels Y, Ericson K (2006) Oncogenic PI3K and its role in cancer. Curr Opin Oncol 18: 77-82. (Pubitemid 43740454)
-
(2006)
Current Opinion in Oncology
, vol.18
, Issue.1
, pp. 77-82
-
-
Samuels, Y.1
Ericson, K.2
-
25
-
-
67749122122
-
Targeting PI3K signalling in cancer: Opportunities, challenges and limitations
-
Engelman JA (2009) Targeting PI3K signalling in cancer: opportunities, challenges and limitations. Nat Rev Cancer 9: 550-562.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 550-562
-
-
Engelman, J.A.1
-
26
-
-
66949179759
-
PI3K p110beta positively regulates lipopolysaccharide-induced IL-12 production in human macrophages and dendritic cells and JNK1 plays a novel role
-
Utsugi M, Dobashi K, Ono A, Ishizuka T, Matsuzaki S, et al. (2009) PI3K p110beta positively regulates lipopolysaccharide-induced IL-12 production in human macrophages and dendritic cells and JNK1 plays a novel role. J Immunol 182: 5225-5231.
-
(2009)
J Immunol
, vol.182
, pp. 5225-5231
-
-
Utsugi, M.1
Dobashi, K.2
Ono, A.3
Ishizuka, T.4
Matsuzaki, S.5
-
27
-
-
34250803183
-
Role of phosphatidylinositol-3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fcgamma receptor ligation in murine macrophages
-
Polumuri SK, Toshchakov VY, Vogel SN (2007) Role of phosphatidylinositol- 3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fc gamma receptor ligation in murine macrophages. J Immunol 179: 236-246. (Pubitemid 46986539)
-
(2007)
Journal of Immunology
, vol.179
, Issue.1
, pp. 236-246
-
-
Polumuri, S.K.1
Toshchakov, V.Y.2
Vogel, S.N.3
-
28
-
-
0036681955
-
Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction
-
Hortner M, Nielsch U, Mayr LM, Johnston JA, Heinrich PC, et al. (2002) Suppressor of cytokine signaling-3 is recruited to the activated granulocytecolony stimulating factor receptor and modulates its signal transduction. J Immunol 169: 1219-1227. (Pubitemid 34809162)
-
(2002)
Journal of Immunology
, vol.169
, Issue.3
, pp. 1219-1227
-
-
Hortner, M.1
Nielsch, U.2
Mayr, L.M.3
Johnston, J.A.4
Heinrich, P.C.5
Haan, S.6
-
29
-
-
79956320988
-
Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer mouse model
-
Jimenez S, Torres M, Vizuete M, Sanchez-Varo R, Sanchez-Mejias E, et al. (2011) Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer mouse model. J Biol Chem 286: 18414-18425.
-
(2011)
J Biol Chem
, vol.286
, pp. 18414-18425
-
-
Jimenez, S.1
Torres, M.2
Vizuete, M.3
Sanchez-Varo, R.4
Sanchez-Mejias, E.5
-
30
-
-
34547484379
-
Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain
-
DOI 10.1111/j.1471-4159.2007.04642.x
-
Ozaita A, Puighermanal E, Maldonado R (2007) Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain. J Neurochem 102: 1105-1114. (Pubitemid 47174245)
-
(2007)
Journal of Neurochemistry
, vol.102
, Issue.4
, pp. 1105-1114
-
-
Ozaita, A.1
Puighermanal, E.2
Maldonado, R.3
-
31
-
-
84882794822
-
Deregulation of PI3K/Akt/mTOR signaling pathways by isoflavones and its implication in cancer treatment
-
Ahmad A, Biersack B, Li Y, Kong D, Bao B, et al. (2013) Deregulation of PI3K/Akt/mTOR signaling pathways by isoflavones and its implication in cancer treatment. Anticancer Agents Med Chem 13: 1014-1024.
-
(2013)
Anticancer Agents Med Chem
, vol.13
, pp. 1014-1024
-
-
Ahmad, A.1
Biersack, B.2
Li, Y.3
Kong, D.4
Bao, B.5
-
32
-
-
34047170343
-
lpr
-
DOI 10.1093/intimm/dxm017
-
Xie C, Patel R, Wu T, Zhu J, Henry T, et al. (2007) PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr. Int Immunol 19: 509-522. (Pubitemid 46523398)
-
(2007)
International Immunology
, vol.19
, Issue.4
, pp. 509-522
-
-
Xie, C.1
Zhu, J.2
Henry, T.3
Bhaskarabhatla, M.4
Samudrala, R.5
Tus, K.6
Gong, Y.7
Zhou, H.8
Wakeland, E.K.9
Zhou, X.J.10
Mohan, C.11
-
33
-
-
33845943018
-
Differential regulation of cytokine release and leukocyte migration by lipopolysaccharide-stimulated primary human lung alveolar type II epithelial cells and macrophages
-
Thorley AJ, Ford PA, Giembycz MA, Goldstraw P, Young A, et al. (2007) Differential regulation of cytokine release and leukocyte migration by lipopolysaccharide-stimulated primary human lung alveolar type II epithelial cells and macrophages. J Immunol 178: 463-473. (Pubitemid 46033630)
-
(2007)
Journal of Immunology
, vol.178
, Issue.1
, pp. 463-473
-
-
Thorley, A.J.1
Ford, P.A.2
Giembycz, M.A.3
Goldstraw, P.4
Young, A.5
Tetley, T.D.6
-
34
-
-
64249111614
-
M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro
-
Leidi M, Gotti E, Bologna L, Miranda E, Rimoldi M, et al. (2009) M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro. J Immunol 182: 4415-4422.
-
(2009)
J Immunol
, vol.182
, pp. 4415-4422
-
-
Leidi, M.1
Gotti, E.2
Bologna, L.3
Miranda, E.4
Rimoldi, M.5
-
35
-
-
84893487976
-
Angiogenic capacity of M1- and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9
-
Zajac E, Schweighofer B, Kupriyanova TA, Juncker-Jensen A, Minder P, et al. (2013) Angiogenic capacity of M1- and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9. Blood 122: 4054-4067.
-
(2013)
Blood
, vol.122
, pp. 4054-4067
-
-
Zajac, E.1
Schweighofer, B.2
Kupriyanova, T.A.3
Juncker-Jensen, A.4
Minder, P.5
-
36
-
-
84873390649
-
Characterization of polarized THP-1 macrophages and polarizing ability of LPS and food compounds
-
Chanput W, Mes JJ, Savelkoul HF, Wichers HJ (2013) Characterization of polarized THP-1 macrophages and polarizing ability of LPS and food compounds. Food Funct 4: 266-276.
-
(2013)
Food Funct
, vol.4
, pp. 266-276
-
-
Chanput, W.1
Mes, J.J.2
Savelkoul, H.F.3
Wichers, H.J.4
-
37
-
-
78951475437
-
Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls
-
Reale M, Patruno A, De Lutiis MA, Pesce M, Felaco M, et al. (2011) Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls. BMC Neurosci 12: 13.
-
(2011)
BMC Neurosci
, vol.12
, pp. 13
-
-
Reale, M.1
Patruno, A.2
De Lutiis, M.A.3
Pesce, M.4
Felaco, M.5
-
38
-
-
84862264011
-
Gr1+ Macrophages and Dendritic Cells Dominate the Inflammatory Infiltrate 12 Hours After Experimental Intracerebral Hemorrhage
-
Hammond MD, Ai Y, Sansing LH (2012) Gr1+ Macrophages and Dendritic Cells Dominate the Inflammatory Infiltrate 12 Hours After Experimental Intracerebral Hemorrhage. Transl Stroke Res 3: s125-s131.
-
(2012)
Transl Stroke Res
, vol.3
-
-
Hammond, M.D.1
Ai, Y.2
Sansing, L.H.3
-
39
-
-
21744451038
-
Oxidation of low-density lipoproteins induces amyloid-like structures that are recognized by macrophages
-
DOI 10.1021/bi050497v
-
Stewart CR, Tseng AA, Mok YF, Staples MK, Schiesser CH, et al. (2005) Oxidation of low-density lipoproteins induces amyloid-like structures that are recognized by macrophages. Biochemistry 44: 9108-9116. (Pubitemid 40943225)
-
(2005)
Biochemistry
, vol.44
, Issue.25
, pp. 9108-9116
-
-
Stewart, C.R.1
Tseng, A.A.2
Mok, Y.-F.3
Staples, M.K.4
Schiesser, C.H.5
Lawrence, L.J.6
Varghese, J.N.7
Moore, K.J.8
Howlett, G.J.9
-
40
-
-
84874519838
-
Pivotal roles of monocytes/macrophages in stroke
-
Chiba T, Umegaki K (2013) Pivotal roles of monocytes/macrophages in stroke. Mediators Inflamm 2013: 759103.
-
(2013)
Mediators Inflamm
, vol.2013
, pp. 759103
-
-
Chiba, T.1
Umegaki, K.2
-
41
-
-
84896275896
-
Identification of a cytoplasmic linker protein as a potential target for neovascularization
-
Xie S, Dong B, Sun X, Tala, He X, et al. (2014) Identification of a cytoplasmic linker protein as a potential target for neovascularization. Atherosclerosis 233: 403-409.
-
(2014)
Atherosclerosis
, vol.233
, pp. 403-409
-
-
Xie, S.1
Dong, B.2
Sun, X.3
Tala4
He, X.5
-
42
-
-
0344921396
-
Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis
-
DOI 10.1073/pnas.0730843100
-
Moulton KS, Vakili K, Zurakowski D, Soliman M, Butterfield C, et al. (2003) Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis. Proc Natl Acad Sci U S A 100: 4736-4741. (Pubitemid 36457799)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.8
, pp. 4736-4741
-
-
Moulton, K.S.1
Vakili, K.2
Zurakowski, D.3
Soliman, M.4
Butterfield, C.5
Sylvin, E.6
Lo, K.-M.7
Gillies, S.8
Javaherian, K.9
Folkman, J.10
|