Accelerating the dissolution of enteric coatings in the upper small intestine: Evolution of a novel PH 5.6 bicarbonate buffer system to assess drug release

International Journal of Pharmaceutics

Volumn 468, Issue 1-2, 2014, Pages 172-177

  Varum, Felipe J O ^a   Merchant, Hamid A ^a   Goyanes, Alvaro ^a   Assi, Pardis ^a   Zboranová, Veronika ^a   Basit, Abdul W ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Bicarbonate buffers; Biorelevant dissolution; Enteric polymers; Gastro resistant coatings; Hypromellose phthalate; pH responsive polymers

Indexed keywords

BUFFER; CITRIC ACID; CITRIC ACID TRIETHYL ESTER; EUDRAGIT; HYDROXYPROPYLMETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE PHTHALATE; PHOSPHATE; PREDNISOLONE; BICARBONATE; ENTERIC COATED TABLET; EUDRAGIT L 30 D-55; METHACRYLIC ACID DERIVATIVE; METHYLCELLULOSE; POLYMER;

ACCELERATION; AIR TEMPERATURE; ARTICLE; COMPARATIVE STUDY; DISPERSION; DRUG RELEASE; DRUG SOLUBILITY; ENTERIC COATED TABLET; HUMAN; IN VITRO STUDY; IN VIVO STUDY; OSMOTIC PRESSURE; PARTICLE SIZE; PH; PRIORITY JOURNAL; SLOW DRUG RELEASE; SMALL INTESTINE; STOMACH PH; TABLET DISINTEGRATION; TABLET MANUFACTURE; VISCOMETRY; ANALOGS AND DERIVATIVES; CHEMISTRY; DUODENUM; KINETICS; MEDICINAL CHEMISTRY; PHARMACEUTICS; PROCEDURES; SOLUBILITY;

BICARBONATES; BUFFERS; CHEMISTRY, PHARMACEUTICAL; DUODENUM; HYDROGEN-ION CONCENTRATION; HYPROMELLOSE DERIVATIVES; KINETICS; METHACRYLATES; METHYLCELLULOSE; POLYMERS; PREDNISOLONE; SOLUBILITY; TABLETS, ENTERIC-COATED; TECHNOLOGY, PHARMACEUTICAL;

EID: 84899543139     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.04.019     Document Type: Article

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