Linsitinib (OSI-906) antagonizes ATP-binding cassette subfamily G member 2 and subfamily C member 10-mediated drug resistance

International Journal of Biochemistry and Cell Biology

Volumn 51, Issue 1, 2014, Pages 111-119

  Zhang, Hui ^a,b   Kathawala, Rishil J ^a   Wang, Yi Jun ^a   Zhang, Yun Kai ^a   Patel, Atish ^a   Shukla, Suneet ^c   Robey, Robert W ^c   Talele, Tanaji T ^a   Ashby Jr , Charles R ^a   Ambudkar, Suresh V ^c   Bates, Susan E ^c   Fu, Li Wu ^b   Chen, Zhe Sheng ^a  

^a ST JOHN'S UNIVERSITY   (United States)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

ABCC10; ABCG2; Linsitinib; Multi drug resistance; Tyrosine kinase inhibitor

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BREAST CANCER RESISTANCE PROTEIN; CISPLATIN; DOCETAXEL; FIRTECAN; LINSITINIB; MITOXANTRONE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 7; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; VINBLASTINE; VINCRISTINE; 3-(8-AMINO-1-(2-PHENYLQUINOLIN-7-YL)IMIDAZO(1,5-A)PYRAZIN-3-YL)-1-METHYLCYCLOBUTANOL; ABC TRANSPORTER; ABCC10 PROTEIN, HUMAN; ABCG2 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; IMIDAZOLE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN; PROTEIN KINASE INHIBITOR; PYRAZINE DERIVATIVE; TUMOR PROTEIN;

ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION; ANTAGONISTS AND INHIBITORS; CARCINOMA, NON-SMALL-CELL LUNG; CHEMICAL STRUCTURE; DRUG EFFECTS; DRUG INTERACTION; HEK293 CELL LINE; LUNG NEOPLASMS; METABOLISM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; DRUG INTERACTIONS; DRUG RESISTANCE, MULTIPLE; HEK293 CELLS; HUMANS; IMIDAZOLES; LUNG NEOPLASMS; MITOXANTRONE; MODELS, MOLECULAR; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; PACLITAXEL; PROTEIN KINASE INHIBITORS; PYRAZINES;

EID: 84899542862     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.03.026     Document Type: Article

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