Poly(lactide-co-glycolide) microspheres for MRI-monitored transcatheter delivery of sorafenib to liver tumors

Journal of Controlled Release

Volumn 184, Issue 1, 2014, Pages 10-17

  Chen, Jeane ^a,b   Sheu, Alexander Y ^b   Li, Weiguo ^b   Zhang, Zhuoli ^b   Kim, Dong Hyun ^b   Lewandowski, Robert J ^b   Omary, Reed A ^a,b   Shea, Lonnie D ^a,b   Larson, Andrew C ^a,b,c  

^a Northwestern University   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c Robert H Lurie Comprehensive Cancer Center Northwestern University ^*  (United States)

Author keywords

Hepatocellular carcinoma; Magnetic resonance imaging; Poly(lactide co glycolide); Sorafenib

Indexed keywords

CELL PROLIFERATION; ENZYME INHIBITION; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; PATIENT TREATMENT; TUMORS;

BIODISTRIBUTIONS; HEPATOCELLULAR CARCINOMA; MICROVESSEL DENSITY; ORAL ADMINISTRATION; POLY LACTIDE-CO-GLYCOLIDE; POLY(LACTIDE-CO-GLYCOLIDE) MICROSPHERES; SORAFENIB; SYSTEMIC TOXICITIES;

MICROSPHERES;

ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; DRUG CARRIER; MICROSPHERE; NICOTINAMIDE; POLYGLACTIN; PROTEIN KINASE INHIBITOR; SORAFENIB;

ANALOGS AND DERIVATIVES; ANIMAL; CARCINOMA, HEPATOCELLULAR; CATHETERIZATION; CELL PROLIFERATION; DRUG EFFECTS; LIVER; LIVER NEOPLASMS; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; RAT; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CATHETERIZATION; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG CARRIERS; LIVER; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; MICROSPHERES; NIACINAMIDE; PHENYLUREA COMPOUNDS; POLYGLACTIN 910; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84899539513     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.04.008     Document Type: Article

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