Depletion of PKM2 leads to impaired glycolysis and cell death in 2-demethoxy-2,3-ethylenediamino hypocrellin B-photoinduced A549 cells

Journal of Photochemistry and Photobiology B: Biology

Volumn 134, Issue , 2014, Pages 1-8

  Zhou, Zhixiang ^a   Liu, Yanghua ^a   Qin, Mengnan ^a   Sheng, Wang ^a   Wang, Xiaoli ^a   Li, Zelin ^a   Zhong, Rugang ^a  

^a BEIJING UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

2 Demethoxy 2,3 ethylenediamino hypocrellin B (EDAHB); A549 cells; Photodynamic therapy (PDT); Proteome; Pyruvate kinase M2 (PKM2)

Indexed keywords

2 DEMETHOXY 2,3 ETHYLENEDIAMINO HYPOCRELLIN B; CALRETICULIN; ELONGATION FACTOR 2; ENDOPLASMIN; LACTIC ACID; PHOTOSENSITIZING AGENT; PRELAMIN A; PYRUVATE KINASE; PYRUVATE KINASE M2; RAB2B PROTEIN; STIP1 PROTEIN; UNCLASSIFIED DRUG; 2-DEMETHOXY-2,3-ETHYLENEDIAMINO HYPOCRELLIN B; CARRIER PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; PERYLENE; PROTEOME; QUINOXALINE DERIVATIVE; SMALL INTERFERING RNA; THYROID HORMONE; THYROID HORMONE-BINDING PROTEINS;

ARTICLE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; GLYCOLYSIS; IN VITRO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PHOTODYNAMIC THERAPY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; APOPTOSIS; DRUG EFFECTS; GENETICS; HUMAN; LIGHT; MASS SPECTROMETRY; METABOLISM; RADIATION RESPONSE; RNA INTERFERENCE; TOXICITY; TUMOR CELL LINE; TWO DIMENSIONAL GEL ELECTROPHORESIS;

APOPTOSIS; CARRIER PROTEINS; CELL LINE, TUMOR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GLYCOLYSIS; HUMANS; LIGHT; MEMBRANE PROTEINS; PERYLENE; PHOTOSENSITIZING AGENTS; PROTEOME; QUINOXALINES; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; THYROID HORMONES;

EID: 84899533261     PISSN: 10111344     EISSN: 18732682     Source Type: Journal    
DOI: 10.1016/j.jphotobiol.2014.03.014     Document Type: Article

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