Controlling methicillin-resistant Staphylococcus aureus (MRSA) in a hospital and the role of hydrogen peroxide decontamination: An interrupted time series analysis

BMJ Open

Volumn 4, Issue 4, 2014, Pages

  Mitchell, Brett G ^a,b   Digney, Wilhelmine ^c   Locket, Phil ^c   Dancer, Stephanie J ^d  

^a AVONDALE COLLEGE OF HIGHER EDUCATION   (Australia)

^b AUSTRALIAN CATHOLIC UNIVERSITY   (Australia)

^c LAUNCESTON GENERAL HOSPITAL   (Australia)

^d HAIRMYRES HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DETERGENT; HYDROGEN PEROXIDE;

ARTICLE; BACTERIAL COLONIZATION; BACTERIUM CONTAMINATION; BACTERIUM ISOLATION; CLEANING; CONTROLLED STUDY; DISINFECTION; GENERAL HOSPITAL; HOSPITAL DISCHARGE; HOSPITAL SUBDIVISIONS AND COMPONENTS; HUMAN; INFECTION CONTROL; MAJOR CLINICAL STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; PATIENT CARE; PATIENT MONITORING; TIME SERIES ANALYSIS; CROSS INFECTION; HEALTH CARE FACILITY; PROCEDURES; PUBLIC HOSPITAL; RETROSPECTIVE STUDY; STAPHYLOCOCCAL INFECTIONS; TASMANIA; WASTE MANAGEMENT;

CROSS INFECTION; DECONTAMINATION; HOSPITALS, PUBLIC; HUMANS; HYDROGEN PEROXIDE; INFECTION CONTROL; INTERRUPTED TIME SERIES ANALYSIS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PATIENTS' ROOMS; RETROSPECTIVE STUDIES; STAPHYLOCOCCAL INFECTIONS; TASMANIA;

EID: 84899525263     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2013-004522     Document Type: Article

References (32)

1. Bouadma L, Mourvillier B, Deiler V, et al. A multifaceted program to prevent ventilator-associated pneumonia: impact on compliance with preventive measures. Crit Care Med 2010;38:789-96.
2. Sannoh S, Clones B, Munoz J, et al. A multimodal approach to central venous catheter hub care can decrease catheter-related bloodstream infection. Am J Infect Control 2010;38:424-9.
3. Mitchell BG, Gardner A. Addressing the need for an infection prevention and control framework that incorporates the role of surveillance: a discussion paper. J Adv Nurs 2014;70:533-42.
4. Dancer SJ. Importance of the environment in meticillin-resistant Staphylococcus aureus acquisition: the case for hospital cleaning. Lancet Infect Dis 2008;8:101-13.
5. Huang SS, Datta R, Platt R. Risk of acquiring antibiotic-resistant bacteria from prior room occupants. Arch Intern Med 2006;166:1945-51. (Pubitemid 44537174)
6. Bonten MJ, Slaughter S, Ambergen AW, et al. The role of "colonization pressure" in the spread of vancomycin-resistant enterococci: an important infection control variable. Arch Intern Med 1998;158:1127-32. (Pubitemid 28242318)
7. Eveillard M, Lancien E, Hidri N, et al. Estimation of methicillin-resistant Staphylococcus aureus transmission by considering colonization pressure at the time of hospital admission. J Hosp Infect 2005;60:27-31. (Pubitemid 40485847)
8. Merrer J, Santoli F, Appere de Vecchi C, et al. "Colonization pressure" and risk of acquisition of methicillin-resistant Staphylococcus aureus in a medical intensive care unit. Infect Control Hosp Epidemiol 2000;21:718-23.
9. Puzniak LA, Mayfield J, Leet T, et al. Acquisition of vancomycin-resistant enterococci during scheduled antimicrobial rotation in an intensive care unit. Clin Infect Dis 2001;33:151-7. (Pubitemid 32643328)
10. Hayden MK, Bonten MJM, Blom DW, et al. Reduction in acquisition of vancomycin-resistant enterococcus after enforcement of routine environmental cleaning measures. Clin Infect Dis 2006;42:1552-60.
11. Cooper RA, Griffith CJ, Malik RE, et al. Monitoring the effectiveness of cleaning in four British hospitals. Am J Infect Control 2007;35:338-41. (Pubitemid 46907322)
12. Griffith CJ, Obee P, Cooper RA, et al. The effectiveness of existing and modified cleaning regimens in a Welsh hospital. J Hosp Infect 2007;66:352-9. (Pubitemid 47215550)
13. Boyce JM, Havill NL, Dumigan DG, et al. Monitoring the effectiveness of hospital cleaning practices by use of an adenosine triphosphate bioluminescence assay. Infect Control Hosp Epidemiol 2009;30:678-84.
14. Dancer SJ, White LF, Lamb J, et al. Measuring the effect of enhanced cleaning in a UK hospital: a prospective cross-over study. BMC Med 2009;7:28.
15. Dancer SJ, Coyne M, Speekenbrink A, et al. MRSA acquisition in an intensive care unit. Am J Infect Control 2006;34:10 -17.
16. Popp W. Cleaning - on the way to evidence-based knowledge. Healthcare Infect 2013;18:1-2.
17. Otter JA. How do we tackle contaminated hospital surfaces? Healthcare Infect 2013;18:42-4.
18. Dettenkofer M. Healthcare environment decontamination. Healthcare Infect 2013;18:47-8.
19. Harbarth S. Hospital-based environmental hygiene: priorities for research. Healthcare Infect 2013;18:49-50.
20. Mitchell B, Dancer SJ, Shaban R, et al. Moving forward with hospital cleaning. Am J Infect Control 2013;41:1138-9.
21. Dettenkofer M, Ammon A, Astagneau P, et al. Infection control - a European research perspective for the next decade. J Hosp Infect 2011;77:7-10.
22. Dancer SJ. Hospital cleaning in the 21st century. Eur J Clin Microbiol Infect Dis 2011;30:1473-81.
23. Grayson L, Russo R, Ryan K, et al. Hand hygiene Australian manual. Canberra: Australian Commission on Safety and Quality in Health Care; 2010.
24. World Health Organisation. Daily defined dose: World Health Organisation, 2009 [updated 13 August 2013]. http://www.whocc.no/ddd/definition-and-general- considera/.
25. International Business Machines Corporation. IBM SPSS Statistics 20.0 edn. New York, 2011.
26. Carling PC, Bartley JM. Evaluating hygienic cleaning in health care settings: what you do not know can harm your patients. Am J Infect Control 2010;38(5, Suppl):S41-50.
27. Aldeyab MA, Monnet DL, López-Lozano JM, et al. Modelling the impact of antibiotic use and infection control practices on the incidence of hospital-acquired methicillin-resistant Staphylococcus aureus: a time-series analysis. J Antimicrob Chemother 2008;62:593-600.
28. Tacconelli E, De Angelis G, Cataldo MA, et al. Antibiotic usage and risk of colonization and infection with antibiotic-resistant bacteria: a hospital population-based study. Antimicrob Agents Chemother 2009;53:4264-9.
29. Liebowitz L, Blunt M. Modification in prescribing practices for third-generation cephalosporins and ciprofloxacin is associated with a reduction in meticillin-resistant Staphylococcus aureus bacteraemia rate. J Hosp Infect 2008;69:328-36.
30. Mitchell B, McGregor A, Wells A, et al. Tasmanian Acute Public Hospitals Healthcare Associated Infection Surveillance Report, Annual Report. Tasmanian Infection Prevention & Control Unit, ed. Hobart: Department of Health and Human Services, 2012.
31. Mitchell B, McGregor A, Wells A, et al. Tasmanian Acute Public Hospitals Healthcare Associated Infection Surveillance Report, Report No.16. Tasmanian Infection Prevention & Control Unit, editor. Hobart: Department of Health and Human Services; 2013.
32. Mitchell B, McGregor A, Brown S, et al. Tasmanian Acute Public Hospitals Healthcare Associated Infection Surveillance Report, Report No.6. Tasmanian Infection Prevention & Control Unit, ed. Hobart: Department of Health and Human Services, 2010.