Effects of early life paracetamol use on the incidence of allergic disease and sensitization: 5 Year follow-up of an Ethiopian birth cohort

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Amberbir, Alemayehu ^a,b   Medhin, Girmay ^c   Hanlon, Charlotte ^c   Britton, John ^b   Davey, Gail ^d   Venn, Andrea ^b  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c ADDIS ABABA UNIVERSITY   (Ethiopia)

^d UNIVERSITY OF BRIGHTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALLERGEN; ANTIBIOTIC AGENT; PARACETAMOL;

ADOLESCENT; ADULT; ALLERGIC DISEASE; ALLERGIC RHINITIS; ARTICLE; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EXPOSURE; DRUG SENSITIZATION; DRUG USE; EARLY CHILDHOOD INTERVENTION; ECZEMA; ETHIOPIA; ETHIOPIAN; ETHNIC GROUP; FEMALE; FEVER; FOLLOW UP; HEADACHE; HIGH RISK POPULATION; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; NEWBORN; OUTCOME ASSESSMENT; POPULATION RESEARCH; PRESCHOOL CHILD; PREVALENCE; PROSPECTIVE STUDY; QUESTIONNAIRE; SENSITIVITY ANALYSIS; SKIN SENSITIVITY; SKIN SENSITIZATION; WHEEZING; ABNORMAL RESPIRATORY SOUND; ASTHMA; CHEMICALLY INDUCED; DEVELOPING COUNTRY; DISEASE PREDISPOSITION; DRUG UTILIZATION; HYPERSENSITIVITY; INFANT; LIFESTYLE; MALE; ONSET AGE; RESPIRATORY TRACT INFECTIONS; RISK FACTOR;

ACETAMINOPHEN; AGE OF ONSET; ASTHMA; CHILD, PRESCHOOL; COHORT STUDIES; CROSS-SECTIONAL STUDIES; DEVELOPING COUNTRIES; DISEASE SUSCEPTIBILITY; DRUG UTILIZATION; ECZEMA; ETHIOPIA; FEMALE; HUMANS; HYPERSENSITIVITY; INCIDENCE; INFANT; INFANT, NEWBORN; LIFE STYLE; MALE; RESPIRATORY SOUNDS; RESPIRATORY TRACT INFECTIONS; RHINITIS, ALLERGIC; RISK FACTORS;

EID: 84899524737     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093869     Document Type: Article

References (30)

1. Eder W, Ege MJ, von Mutius E (2006) The Asthma Epidemic. N Engl J Med; 355(21):2226-2235. (Pubitemid 44791164)
2. Yemaneberhan H, Bekele Z, Venn A, Lewis S, Parry E, et al. (1997) Prevalence of wheeze and asthma and relation to atopy in urban and rural Ethiopia. Lancet; 350(9071):85-90. (Pubitemid 27313632)
3. Asher MI, Montefort S, Bjorksten B, Lai CKW, Strachan DP, et al. (2006) Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet; 368(9537):733-743. (Pubitemid 44279052)
4. Moffat MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, et al. (2010) A Large-Scale, Consortium-Based Genome wide Association Study of Asthma. N Engl J Med; 363(13):1211-1221.
5. Ege MJ, Mayer M, Normand AC, Genuneit J, Cookson W, et al. (2011) Exposure to Environmental Microorganisms and Childhood Asthma. N Engl J Med; 364(8):701-709.
6. Etminan M., Sadatsafavi M., Jafari S, Doyle-Waters M, FitzGerald JM (2009) Acetaminophen use and the risk of asthma in children and adults. A systematic review and meta analysis. Chest; 136:1316-1323.
7. Eyers S, Weatherall M, Jefferies S, Beasley R (2011) Paracetamol in pregnancy and the risk of wheezing in offspring: a systematic review and meta-analysis. Clin Exp Allergy; 41(4):482-489.
8. Davey G, Berhane Y, Duncan P, ref-Adib G, Britton J, et al. (2005) Use of acetaminophen and the risk of self-reported allergic symptoms and skin sensitization in Butajira, Ethiopia. J Allergy Clin Immunol; 116(4):863-868. (Pubitemid 41400553)
9. Amberbir A, Medhin G, Alem A, Britton J, Davey G, et al. (2011) The role of acetaminophen and geohelminth infection on the incidence of wheeze and eczema: a longitudinal birth-cohort study. Am J Respir Crit Care Med; 183(2):165-170.
10. Farquhar H, Stewart A, Mitchell E, Crane J, Eyers S, et al. (2010) The role of paracetamol in the pathogenesis of asthma. Clin Exp Allergy; 40:32-41.
11. Beasley RW, Clayton TO, Crane J, Crane J, Lai CKW, et al. (2011) Acetaminophen use and risk of asthma, rhinoconjunctivitis, and eczema in adolescents: International Study of Asthma and Allergies in Childhood Phase Three. Am J Respir Crit Care Med; 183(2):171-178.
12. Beasley R, Clayton T, Crane J, von Mutius E, Lai CKW, et al. (2008) Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme. Lancet; 372(9643):1039-1048.
13. Shaheen SO, Newson RB, Sherriff A, Henderson AJ, Heron JE, et al. (2002) Paracetamol use in pregnancy and wheezing in early childhood. Thorax; 57(11):958-963. (Pubitemid 35316274)
14. Barr RG, Wentowski CC, Curhan GC, Somers SC, Stampfer MJ, et al. (2004) Prospective study of acetaminophen use and newly diagnosed asthma among women. Am J Respir Crit Care Med; 169(7):836-841. (Pubitemid 38402460)
15. Lowe AJ, Carlin JB, Bennett CM, Hosking CS, Allen KJ, et al (2010). Paracetamol use in early life and asthma: prospective birth cohort study. BMJ; 341(c4616).
16. Berhane Y, Wall S, Kebede D, Emmelin A, Enquselassie F, et al. (1999) Establishing an epidemiological field laboratory in rural areas-potential for public health research and interventions. Ethiop J Health Dev; 13:1-47.
17. Hanlon C, Medhin G, Alem A, Tesfaye F, Lakew Z, et al. (2009) Impact of antenatal common mental disorders upon perinatal outcomes in Ethiopia: the PMaMiE population-based cohort study. Trop Med Int Health; 14(2):156-166.
18. Belyhun Y, Amberbir A, Medhin G, Erko B, Hanlon C, et al. (2010) Prevalence and risk factors of wheeze and eczema in one year old children: the Butajira birth cohort, Ethiopia. Clin Exp Allergy; (40):619-626.
19. Asher MI, Keil U, Anderson HR, Beasley R, Crane J, et al. (1995) International Study of Asthma and Allergies in Childhood (ISAAC): Rationale and methods. Eur Respir J; 8:483-491.
20. Amberbir A, Medhin G, Erku W, Alem A, Simms R, et al. (2011) Effects of Helicobacter pylori, geohelminth infection and selected commensal bacteria on the risk of allergic disease and sensitization in 3-year-old Ethiopian children. Clin Exp Allergy; 41(10):1422-1430.
21. Prescott SL, Macaubas C, Smallacombe T, Holt BJ, Sly PD, et al. (1999) Development of allergen-specific T-cell memory in atopic and normal children. Lancet; 353(9148):196-200. (Pubitemid 29088031)
22. Illi S, von Mutius E, Lau S, Bergmann, Niggemann B, et al. (2001) Early childhood infectious diseases and the development of asthma up to school age: a birth cohort study. BMJ; 322(7283):390-395. (Pubitemid 32193268)
23. Rebordosa C, Kogevinas M, Sorensen HT, Olsen J (2008) Pre-natal exposure to paracetamol and risk of wheezing and asthma in children: A birth cohort study. Int J Epidemiol; 37(3):583-590. (Pubitemid 351804012)
24. Perzanowski MS, Miller RL, Ali DB, Garfinkel RS, Chew GL, et al. (2008) Prenatal acetaminophen use is a risk for wheeze at age 5 years in a low income urban population with a high risk for asthma. J Allergy Clin Immunol; (Supp 1):S231.
25. Lesko SM, Louik C, Vezina RM, Mitchell AA (2002) Asthma morbidity after the short-term use of ibuprofen in children. Pediatrics; 109(2):e20.
26. Nuttall SL, Khan JN, Thorpe GH, Langford N, Kendall MJ (2003) The impact of therapeutic doses of paracetamol on serum total antioxidant capacity. J Clin Pharm Ther; 28(4):289-294. (Pubitemid 37041137)
27. Nuttall SL,Williams J, Kendall MJ (2003)Does paracetamol cause asthma? J Clin Pharm Ther; 28(4):251-257. (Pubitemid 37041132)
28. Micheli L, Cerretani D, Fiaschi A, Gioorgi G, Romeo R, et al. (1994) Effect of acetaminophen on glutathione levels in rat testis and lung. Environ Health Perspect; (Supp 9):63-64.
29. Peterson JD, Herzenberg LA, Vasquez K, Waltenbaugh C (1998) Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns. Proceedings of the National Academy of Sciences of the United States of America; 95(6):3071-3076. (Pubitemid 28135856)
30. Nassini R, Materazzi S, Andre E, Sartiani L, Aldini G, et al. (2010) Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents. FASEB J; 24(12):4904-4916