Gabapentin inhibits bortezomib-induced mechanical allodynia through supraspinal action in mice

Journal of Pharmacological Sciences

Volumn 124, Issue 4, 2014, Pages 502-510

  Kitamura, Ryo ^a   Andoh, Tsugunobu ^a   Mizoguchi, Shizuka ^a   Saito, Yukako ^b   Takahata, Hiroki ^b   Kuraishi, Yasushi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Allodynia; Bortezomib; Descending noradrenergic system; Gabapentin; Noradrenaline

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL ALPHA2DELTA 1 SUBUNIT; GABAPENTIN; NORADRENALIN; SEROTONIN; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MECHANISM; HYPERALGESIA; MALE; MOUSE; NONHUMAN; NORADRENERGIC SYSTEM; PERIPHERAL NEUROPATHY; PROTEIN EXPRESSION; SAPHENOUS NERVE;

ADRENERGIC NEURONS; AMINES; ANIMALS; ANTINEOPLASTIC AGENTS; BORONIC ACIDS; CYCLOHEXANECARBOXYLIC ACIDS; GAMMA-AMINOBUTYRIC ACID; HYPERALGESIA; MICE; MICE, INBRED C57BL; NOREPINEPHRINE; PYRAZINES; SPINAL CORD;

EID: 84899509358     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.13274FP     Document Type: Article

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