Bumetanide protects focal cerebral ischemia-reperfusion injury in rat

International Journal of Clinical and Experimental Pathology

Volumn 7, Issue 4, 2014, Pages 1487-1494

  Wang, Genbao ^a,b   Huang, Huansen ^a   He, Yanbing ^a   Ruan, Lin ^a   Huang, Junjie ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b Department of Anesthesiology Affiliated Zhong San Chinese Hospital of Guang Zhou Chinese University   (China)

Author keywords

Bumetanide; Cerebral ischemia reperfusion injury; Neuroprotection

Indexed keywords

BUMETANIDE; COTRANSPORTER; LOOP DIURETIC AGENT; POTASSIUM-CHLORIDE SYMPORTERS; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1;

ANIMAL; BRAIN CORTEX; BRAIN ISCHEMIA; DISEASE MODEL; INTRAVENOUS DRUG ADMINISTRATION; MALE; METABOLISM; PATHOLOGY; RAT; REPERFUSION INJURY; TIME;

ANIMALS; BRAIN ISCHEMIA; BUMETANIDE; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; INJECTIONS, INTRAVENOUS; MALE; RATS; REPERFUSION INJURY; SODIUM POTASSIUM CHLORIDE SYMPORTER INHIBITORS; SOLUTE CARRIER FAMILY 12, MEMBER 2; SYMPORTERS; TIME FACTORS;

EID: 84899494373     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Haas M, Forbush B 3rd. The Na-K-Cl cotransporter of secretory epithelia. Ann Rev Physiol 2000; 62: 515-534.
2. Russell JM. Sodium-potassium-chloride co-transport. Physiol Rev 2000; 80: 211-276.
3. Blaesse P, Airaksinen MS, Rivera C, Kaila K. Cation-Chloride Cotransporters and Neuronal Function. Neuron 2009; 61: 820-838.
4. Hebert SC, Mount DB, Gamba G. Molecular physiology of cation-coupled Cl-cotransport: the SLC12 family. Pflugers Areh 2004; 447: 580-593.
5. Khirug S, Yamada J, Afzalov R, Voipio J, Khiroug L, Kaila K. GABAergic depolarization of the axon initial segment in cortical principal neurons is caused by the Na-K-2Cl cotransporter NKCC1. J Neurosci 2008; 28: 4635-4639.
6. Yamada J, Okabe A, Toyoda H, Kilb W, Luhmann HJ, Fukuda A. Cl-uptake promoting depolarizing GABA actions in immature rat neocortical neurones is mediated by NKCC1. J Physiol 2004; 557: 829-841.
7. Kahle KT, Simard JM, Staley KJ, Nahed BV, Jones PS, Sun D. Molecular mechanisms of ischemic cerebral edema: role of electroneutral ion transport. Physiology (Bethesda) 2009; 24: 257-265.
8. Rivera C, Voipio J, Payne JA, Ruusuvuori E, Lahtinen H, Lamsa K, Pirvola U, Saarma M, Kaila K. The K-C co-transporter kcc2 rendersgaba hyperpolarizing during neuronal maturation. Nature 1999; 397: 251-255.
9. Galeffi F, Sah R, Pond BB, George A, Schwartz-Bloom RD. Changes in intracellular chloride after oxygen-glucose deprivation of the adult hippocampal slice: Effect of diazepam. J Neurosci 2004; 24: 4478-4488.
10. Papp E, Rivera C, Kaila K, Freund TF. Relationship between neuronal vulnerability and potassium-chloride cotransporter 2 immunoreactivity in hippocampus following transient fore-brain ischemia. Neurosci 2008; 154: 677-689.
11. Lu KT, Wu CY, Cheng NC, Wo YY, Yang JT, Yen HH, Yang YL. Inhibition of the Na+-K+-2Cl-cotransporter in choroid plexus attenuatestraumatic brain injury-induced brain edema and neuronal damage. Eur J Pharmacol 2006; 548: 99-105.
12. Liu Y, Shangguan Y, Barks JD, Silverstein FS. Bumetanide augments the neuroprotective efficacy of phenobarbital plus hypothermia in a neonatal hypoxia-ischemia model. Pediatr Res 2012; 71: 559-565.
13. Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989; 20: 84-91.
14. Thored P, Wood J, Arvidsson A, Cammenga J, Kokaia Z, Lindvall O. Long-term neuroblast migration along blood vessels in an area with transient angiogenesis and increased vascularization after stroke. Stroke 2007; 11: 3032-3039.
15. Swanson RA, Morton MT, Tsao-Wu G, Savalos RA, Davidson C, Sharp FR. A semiautomated method for measuring brain infarct volume. J Cereb Blood Flow Metab 1990; 10: 290-293.
16. Yan Y, Dempsey RJ, Sun D. Na+-K+-Cl-contransporter in rat focal cerebral ischemia. J Cereb Blood Flow Metab 2001; 21: 711-721.
17. Yan Y, Dempsey RJ, Flemmer A, Forbush B, Sun D. Inhibition of Na+-K+-Cl-cotransporter during focal cerebral ischemia decreases edema and neuronal damage. Brain Res 2003; 961: 22-31.
18. Chen H, Luo J, Kintner DB, Shull GE, Sun D. Na+-dependent chloride transporter (NKCC1)-null mice exhibit less gray and white matter damage after focal cerebral ischemia. J Cereb Blood Flow Metab 2005; 25: 54-66.
19. Forbush B 3rd, Palfrey HC. [3H]bumetanide binding to membranes isolated from dog kidney outer medulla. Relationship to the Na, K, Cl co-transport system. J Biol Chem 1983; 258: 11787-11792.
20. O'Donnell ME, Tran L, Lam TI, Liu XB, Anderson SE. Bumetanide inhibition of the blood-brain barrier Na-K-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke. J Cereb Blood Flow Metab 2004; 24: 1046-1056.
21. Su G, Haworth RA, Dempsey RJ, Sun D. Regulation of Na(+)-K(+)-Cl(-) cotransporter in primary astrocytes by dibutyryl cAMP and high [K(+)](o). Am J Physiol 2000; 279: C1710-21.
22. Payne JA, Rivera C, Voipio J, Kaila K. Cation-chloride co-transporters in neuronal communication, development and trauma. Trends Neurosci 2003; 26: 199-206.
23. Jaenisch N, Witte OW, Frahm C. Downregulation of potassium chloride cotransporter KCC2 after transient focal cerebral ischemia. Stroke 2010; 41: e151-e159.
24. Gillen CM, Brill S, Payne JA, Forbush B 3rd. Molecular cloning and funetional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family. J Biol Chem 1996; 271: 16237-1624.
25. Tyzio R, Cossart R, Khalilov I, Minlebaev M, Hubner CA, Represa A, Ben-Ari Y, Khazipov R. Maternal oxytocin triggers a transient inhibitory switch in gaba signaling in the fetal brain during delivery. Science 2006; 314: 1788-1792.