Cell surface engineering to enhance mesenchymal stem cell migration toward an SDF-1 gradient

Biomaterials

Volumn 35, Issue 21, 2014, Pages 5627-5635

  Won, Young Wook ^a   Patel, Amit N ^a   Bull, David A ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

CXCR4; Mesenchymal stem cell; Myocardial infarction; SDF 1

Indexed keywords

CELL MEMBRANES; FLOWCHARTING; RECOMBINANT PROTEINS; STEM CELLS;

CELL SURFACE ENGINEERING; CXC CHEMOKINE RECEPTOR 4; CXCR4; MESENCHYMAL STEM CELL; MYOCARDIAL INFARCTION; SDF-1; SURFACE MODIFICATION METHODS; THERAPEUTIC EFFICACY;

CELL CULTURE;

CHEMOKINE RECEPTOR CXCR4; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; MACROGOL DERIVATIVE; RECOMBINANT PROTEIN; STROMAL CELL DERIVED FACTOR 1;

CELL ADHESION; CELL MOTION; CELL PROLIFERATION; CHEMISTRY; GENETICS; HEK293 CELL LINE; HUMAN; MESENCHYMAL STROMA CELL; METABOLISM; MYOCARDIAL INFARCTION; PHYSIOLOGY; STEM CELL; UPREGULATION;

CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CHEMOKINE CXCL12; HEK293 CELLS; HUMANS; MESENCHYMAL STROMAL CELLS; MYOCARDIAL INFARCTION; POLYETHYLENE GLYCOLS; RECEPTORS, CXCR4; RECOMBINANT PROTEINS; STEM CELLS; UP-REGULATION;

EID: 84899493457     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.03.070     Document Type: Article

References (39)

1. Berry M.F., Engler A.J., Woo Y.J., Pirolli T.J., Bish L.T., Jayasankar V., et al. Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance. Am J Physiol Heart Circ Physiol 2006, 290:H2196-H2203.
2. Silva G.V., Litovsky S., Assad J.A., Sousa A.L., Martin B.J., Vela D., et al. Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation 2005, 111:150-156.
3. Tomita S., Mickle D.A., Weisel R.D., Jia Z.Q., Tumiati L.C., Allidina Y., et al. Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation. JThorac Cardiovasc Surg 2002, 123:1132-1140.
4. Kinnaird T., Stabile E., Burnett M.S., Shou M., Lee C.W., Barr S., et al. Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation 2004, 109:1543-1549.
5. Kinnaird T., Stabile E., Burnett M.S., Lee C.W., Barr S., Fuchs S., et al. Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote invitro and invivo arteriogenesis through paracrine mechanisms. Circ Res 2004, 94:678-685.
6. Barbash I.M., Chouraqui P., Baron J., Feinberg M.S., Etzion S., Tessone A., et al. Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution. Circulation 2003, 108:863-868.
7. Wynn R.F., Hart C.A., Corradi-Perini C., O'Neill L., Evans C.A., Wraith J.E., et al. Asmall proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow. Blood 2004, 104:2643-2645.
8. Rombouts W.J., Ploemacher R.E. Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture. Leukemia 2003, 17:160-170.
9. Assis A.C., Carvalho J.L., Jacoby B.A., Ferreira R.L., Castanheira P., Diniz S.O., et al. Time-dependent migration of systemically delivered bone marrow mesenchymal stem cells to the infarcted heart. Cell Transplant 2010, 19:219-230.
10. Karp J.M., Leng Teo G.S. Mesenchymal stem cell homing: the devil is in the details. Cell Stem Cell 2009, 4:206-216.
11. Abbott J.D., Huang Y., Liu D., Hickey R., Krause D.S., Giordano F.J. Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 2004, 110:3300-3305.
12. Askari A.T., Unzek S., Popovic Z.B., Goldman C.K., Forudi F., Kiedrowski M., et al. Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet 2003, 362:697-703.
13. Tang Y.L., Qian K., Zhang Y.C., Shen L., Phillips M.I. Mobilizing of haematopoietic stem cells to ischemic myocardium by plasmid mediated stromal-cell-derived factor-1alpha (SDF-1alpha) treatment. Regul Pept 2005, 125:1-8.
14. Misao Y., Takemura G., Arai M., Ohno T., Onogi H., Takahashi T., et al. Importance of recruitment of bone marrow-derived CXCR4+ cells in post-infarct cardiac repair mediated by G-CSF. Cardiovasc Res 2006, 71:455-465.
15. Phinney D.G., Prockop D.J. Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair-current views. Stem Cells 2007, 25:2896-2902.
16. Cheng Z., Ou L., Zhou X., Li F., Jia X., Zhang Y., et al. Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance. Mol Ther 2008, 16:571-579.
17. Ghadge S.K., Muhlstedt S., Ozcelik C., Bader M. SDF-1alpha as a therapeutic stem cell homing factor in myocardial infarction. Pharmacol Ther 2011, 129:97-108.
18. Shi M., Li J., Liao L., Chen B., Li B., Chen L., et al. Regulation of CXCR4 expression in human mesenchymal stem cells by cytokine treatment: role in homing efficiency in NOD/SCID mice. Haematologica 2007, 92:897-904.
19. Liu H., Xue W., Ge G., Luo X., Li Y., Xiang H., et al. Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1alpha in MSCs. Biochem Biophys Res Commun 2010, 401:509-515.
20. Teramura Y., Kaneda Y., Totani T., Iwata H. Behavior of synthetic polymers immobilized on a cell membrane. Biomaterials 2008, 29:1345-1355.
21. Seibert C., Veldkamp C.T., Peterson F.C., Chait B.T., Volkman B.F., Sakmar T.P. Sequential tyrosine sulfation of CXCR4 by tyrosylprotein sulfotransferases. Biochemistry 2008, 47:11251-11262.
22. Doranz B.J., Orsini M.J., Turner J.D., Hoffman T.L., Berson J.F., Hoxie J.A., et al. Identification of CXCR4 domains that support coreceptor and chemokine receptor functions. JVirol 1999, 73:2752-2761.
23. Farzan M., Babcock G.J., Vasilieva N., Wright P.L., Kiprilov E., Mirzabekov T., et al. The role of post-translational modifications of the CXCR4 amino terminus in stromal-derived factor 1 alpha association and HIV-1 entry. JBiol Chem 2002, 277:29484-29489.
24. Veldkamp C.T., Seibert C., Peterson F.C., Sakmar T.P., Volkman B.F. Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12). JMol Biol 2006, 359:1400-1409.
25. Veldkamp C.T., Seibert C., Peterson F.C., De la Cruz N.B., Haugner J.C., Basnet H., et al. Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12. Sci Signal 2008, 1:ra4.
26. Nagasawa T., Nakajima T., Tachibana K., Iizasa H., Bleul C.C., Yoshie O., et al. Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc Natl Acad Sci U S A 1996, 93:14726-14729.
27. Ratajczak M.Z., Zuba-Surma E., Kucia M., Reca R., Wojakowski W., Ratajczak J. The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis. Leukemia 2006, 20:1915-1924.
28. Kucia M., Jankowski K., Reca R., Wysoczynski M., Bandura L., Allendorf D.J., et al. CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion. JMol Histol 2004, 35:233-245.
29. Wong D., Korz W. Translating an antagonist of chemokine receptor CXCR4: from bench to bedside. Clin Cancer Res 2008, 14:7975-7980.
30. Pillarisetti K., Gupta S.K. Cloning and relative expression analysis of rat stromal cell derived factor-1 (SDF-1)1: SDF-1 alpha mRNA is selectively induced in rat model of myocardial infarction. Inflammation 2001, 25:293-300.
31. Tang Y.L., Zhu W., Cheng M., Chen L., Zhang J., Sun T., et al. Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression. Circ Res 2009, 104:1209-1216.
32. Chang L.T., Yuen C.M., Sun C.K., Wu C.J., Sheu J.J., Chua S., et al. Role of stromal cell-derived factor-1alpha, level and value of circulating interleukin-10 and endothelial progenitor cells in patients with acute myocardial infarction undergoing primary coronary angioplasty. Circ J 2009, 73:1097-1104.
33. Kucia M., Dawn B., Hunt G., Guo Y., Wysoczynski M., Majka M., et al. Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction. Circ Res 2004, 95:1191-1199.
34. Lapidot T., Petit I. Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp Hematol 2002, 30:973-981.
35. Shen H., Cheng T., Olszak I., Garcia-Zepeda E., Lu Z., Herrmann S., et al. CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells. JImmunol 2001, 166:5027-5033.
36. Papayannopoulou T., Priestley G.V., Bonig H., Nakamoto B. The role of G-protein signaling in hematopoietic stem/progenitor cell mobilization. Blood 2003, 101:4739-4747.
37. Liles W.C., Broxmeyer H.E., Rodger E., Wood B., Hubel K., Cooper S., et al. Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood 2003, 102:2728-2730.
38. Hattori K., Heissig B., Tashiro K., Honjo T., Tateno M., Shieh J.H., et al. Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood 2001, 97:3354-3360.
39. Sweeney E.A., Lortat-Jacob H., Priestley G.V., Nakamoto B., Papayannopoulou T. Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells. Blood 2002, 99:44-51.