-
2
-
-
76949106050
-
Treatment options for small cell lung cancer - do we have more choice?
-
Puglisi M., Dolly S., Faria A., Myerson J.S., Popat S., O'Brien M.E. Treatment options for small cell lung cancer - do we have more choice?. Br J Cancer 2010, 102(4):629-638.
-
(2010)
Br J Cancer
, vol.102
, Issue.4
, pp. 629-638
-
-
Puglisi, M.1
Dolly, S.2
Faria, A.3
Myerson, J.S.4
Popat, S.5
O'Brien, M.E.6
-
3
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004, 350(21):2129-2139.
-
(2004)
N Engl J Med
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
-
4
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez J.G., Janne P.A., Lee J.C., Tracy S., Greulich H., Gabriel S., et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004, 304(5676):1497-1500.
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
-
5
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
-
Mitsudomi T., Morita S., Yatabe Y., Negoro S., Okamoto I., Tsurutani J., et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010, 11(2):121-128.
-
(2010)
Lancet Oncol
, vol.11
, Issue.2
, pp. 121-128
-
-
Mitsudomi, T.1
Morita, S.2
Yatabe, Y.3
Negoro, S.4
Okamoto, I.5
Tsurutani, J.6
-
6
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M., Inoue A., Kobayashi K., Negoro S., Okamoto I., Tsurutani J., et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010, 362(25):2380-2388.
-
(2010)
N Engl J Med
, vol.362
, Issue.25
, pp. 2380-2388
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
Negoro, S.4
Okamoto, I.5
Tsurutani, J.6
-
7
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL CTONG-0802): a multicentre, open-label, randomised, phase 3 study
-
Zhou C., Wu Y.L., Chen G., Feng J., Liu X.Q., Wang C., et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011, 12(8):735-742.
-
(2011)
Lancet Oncol
, vol.12
, Issue.8
, pp. 735-742
-
-
Zhou, C.1
Wu, Y.L.2
Chen, G.3
Feng, J.4
Liu, X.Q.5
Wang, C.6
-
8
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
-
Rosell R., Carcereny E., Gervais R., Vergnenegre A., Massuti B., Felip E., et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012, 13(3):239-246.
-
(2012)
Lancet Oncol
, vol.13
, Issue.3
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
Vergnenegre, A.4
Massuti, B.5
Felip, E.6
-
9
-
-
84870996017
-
Non-small cell lung cancer
-
Ettinger D.S., Akerley W., Borghaei H., Chang A.C., Cheney R.T., Chirieac L.R., et al. Non-small cell lung cancer. J Natl Compr Cancer Netw 2012, 10(10):1236-1271.
-
(2012)
J Natl Compr Cancer Netw
, vol.10
, Issue.10
, pp. 1236-1271
-
-
Ettinger, D.S.1
Akerley, W.2
Borghaei, H.3
Chang, A.C.4
Cheney, R.T.5
Chirieac, L.R.6
-
10
-
-
84866597083
-
Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
Peters S., Adjei A.A., Gridelli C., Reck M., Kerr K., Felip E. Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2012, 23(Suppl. 7):vii56-vii64.
-
(2012)
Ann Oncol
, vol.23
, Issue.SUPPL. 7
, pp. 756-764
-
-
Peters, S.1
Adjei, A.A.2
Gridelli, C.3
Reck, M.4
Kerr, K.5
Felip, E.6
-
11
-
-
80053271947
-
Small cell lung cancer: new clinical recommendations and current status of biomarker assessment
-
Planchard D., Le Pechoux C. Small cell lung cancer: new clinical recommendations and current status of biomarker assessment. Eur J Cancer 2011, 47(Suppl. 3):S272-S283.
-
(2011)
Eur J Cancer
, vol.47
, Issue.SUPPL. 3
-
-
Planchard, D.1
Le Pechoux, C.2
-
12
-
-
84899481824
-
-
(in press)
-
Serizawa M., Koh Y., Kenmotsu H., Isaka M., Murakami H., Akamatsu H., et al. Assessment of mutational profile of Japanese lung adenocarcinoma patients by multitarget assays: a prospective single-institute study cancer 2014, (in press).
-
(2014)
Assessment of mutational profile of Japanese lung adenocarcinoma patients by multitarget assays: a prospective single-institute study cancer
-
-
Serizawa, M.1
Koh, Y.2
Kenmotsu, H.3
Isaka, M.4
Murakami, H.5
Akamatsu, H.6
-
13
-
-
78049515002
-
Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases
-
Sun Y., Ren Y., Fang Z., Li C., Fang R., Gao B., et al. Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases. J Clin Oncol 2010, 28(30):4616-4620.
-
(2010)
J Clin Oncol
, vol.28
, Issue.30
, pp. 4616-4620
-
-
Sun, Y.1
Ren, Y.2
Fang, Z.3
Li, C.4
Fang, R.5
Gao, B.6
-
14
-
-
82355161909
-
Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers
-
Li C., Fang R., Sun Y., Han X., Li F., Gao B., et al. Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers. PLoS ONE 2011, 6(11):e28204.
-
(2011)
PLoS ONE
, vol.6
, Issue.11
-
-
Li, C.1
Fang, R.2
Sun, Y.3
Han, X.4
Li, F.5
Gao, B.6
-
15
-
-
84866851740
-
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
-
Peifer M., Fernandez-Cuesta L., Sos M.L., George J., Seidel D., Kasper L.H., et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet 2012, 44(10):1104-1110.
-
(2012)
Nat Genet
, vol.44
, Issue.10
, pp. 1104-1110
-
-
Peifer, M.1
Fernandez-Cuesta, L.2
Sos, M.L.3
George, J.4
Seidel, D.5
Kasper, L.H.6
-
16
-
-
84866849548
-
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
-
Rudin C.M., Durinck S., Stawiski E.W., Poirier J.T., Modrusan Z., Shames D.S., et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet 2012, 44(10):1111-1116.
-
(2012)
Nat Genet
, vol.44
, Issue.10
, pp. 1111-1116
-
-
Rudin, C.M.1
Durinck, S.2
Stawiski, E.W.3
Poirier, J.T.4
Modrusan, Z.5
Shames, D.S.6
-
17
-
-
84899487371
-
Comprehensive genomic analysis of small cell lung cancer in Asian patients
-
Umemura S., Goto K., Mimaki S., Ishii G., Ohmatsu H., Niho S., et al. Comprehensive genomic analysis of small cell lung cancer in Asian patients. ASCO Meet Abstr 2013, 31(Suppl. 15):7512.
-
(2013)
ASCO Meet Abstr
, vol.31
, Issue.SUPPL. 15
, pp. 7512
-
-
Umemura, S.1
Goto, K.2
Mimaki, S.3
Ishii, G.4
Ohmatsu, H.5
Niho, S.6
-
18
-
-
34548446446
-
PIK3CA mutation and amplification in human lung cancer
-
Okudela K., Suzuki M., Kageyama S., Bunai T., Nagura K., Igarashi H., et al. PIK3CA mutation and amplification in human lung cancer. Pathol Int 2007, 57(10):664-671.
-
(2007)
Pathol Int
, vol.57
, Issue.10
, pp. 664-671
-
-
Okudela, K.1
Suzuki, M.2
Kageyama, S.3
Bunai, T.4
Nagura, K.5
Igarashi, H.6
-
19
-
-
0142227019
-
Targeting the PI3K-Akt pathway in human cancer: rationale and promise
-
Luo J., Manning B.D., Cantley L.C. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 2003, 4(4):257-262.
-
(2003)
Cancer Cell
, vol.4
, Issue.4
, pp. 257-262
-
-
Luo, J.1
Manning, B.D.2
Cantley, L.C.3
-
20
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels Y., Wang Z., Bardelli A., Silliman N., Ptak J., Szabo S., et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004, 304(5670):554.
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
-
21
-
-
84871995364
-
Targeting the phosphoinositide 3-kinase p110-alpha isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer
-
Wojtalla A., Fischer B., Kotelevets N., Mauri F.A., Sobek J., Rehrauer H., et al. Targeting the phosphoinositide 3-kinase p110-alpha isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer. Clin Cancer Res 2013, 19(1):96-105.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.1
, pp. 96-105
-
-
Wojtalla, A.1
Fischer, B.2
Kotelevets, N.3
Mauri, F.A.4
Sobek, J.5
Rehrauer, H.6
-
22
-
-
68249093818
-
Targeting the phosphoinositide 3-kinase pathway in cancer
-
Liu P., Cheng H., Roberts T.M., Zhao J.J. Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov 2009, 8(8):627-644.
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.8
, pp. 627-644
-
-
Liu, P.1
Cheng, H.2
Roberts, T.M.3
Zhao, J.J.4
-
23
-
-
84885431490
-
Safety, pharmacokinetics, and preliminary activity of the α-specific PI3K inhibitor BYL719: results from the first-in-human study
-
Gonzalez-Angulo A.M., Juric D., Argiles G., Schellens J.H., Burris H.A., Berlin J., et al. Safety, pharmacokinetics, and preliminary activity of the α-specific PI3K inhibitor BYL719: results from the first-in-human study. ASCO Meet Abstr 2013, 31(Suppl. 15):2531.
-
(2013)
ASCO Meet Abstr
, vol.31
, Issue.SUPPL. 15
, pp. 2531
-
-
Gonzalez-Angulo, A.M.1
Juric, D.2
Argiles, G.3
Schellens, J.H.4
Burris, H.A.5
Berlin, J.6
-
24
-
-
84874648611
-
A pharmacokinetic (PK) pharmacodynamic (PD) driven first-in-human study of the oral class I PI3K inhibitor CH5132799, in patients with advanced solid tumors
-
Omlin A.G., Spicer J.F., Sarker D., Pinato D.J., Agarwal R., Cassier P.A., et al. A pharmacokinetic (PK) pharmacodynamic (PD) driven first-in-human study of the oral class I PI3K inhibitor CH5132799, in patients with advanced solid tumors. ASCO Meet Abstr 2012, 30(Suppl. 15):3022.
-
(2012)
ASCO Meet Abstr
, vol.30
, Issue.SUPPL. 15
, pp. 3022
-
-
Omlin, A.G.1
Spicer, J.F.2
Sarker, D.3
Pinato, D.J.4
Agarwal, R.5
Cassier, P.A.6
-
25
-
-
58149149814
-
Epidermal growth factor receptor mutations in small cell lung cancer
-
Tatematsu A., Shimizu J., Murakami Y., Horio Y., Nakamura S., Hida T., et al. Epidermal growth factor receptor mutations in small cell lung cancer. Clin Cancer Res 2008, 14(19):6092-6096.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.19
, pp. 6092-6096
-
-
Tatematsu, A.1
Shimizu, J.2
Murakami, Y.3
Horio, Y.4
Nakamura, S.5
Hida, T.6
-
26
-
-
34748863599
-
Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung
-
Fukui T., Tsuta K., Furuta K., Watanabe S., Asamura H., Ohe Y., et al. Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung. Cancer Sci 2007, 98(11):1714-1719.
-
(2007)
Cancer Sci
, vol.98
, Issue.11
, pp. 1714-1719
-
-
Fukui, T.1
Tsuta, K.2
Furuta, K.3
Watanabe, S.4
Asamura, H.5
Ohe, Y.6
-
27
-
-
0037314212
-
Neuroendocrine and cytokeratin serum markers as prognostic determinants of small cell lung cancer
-
Pujol J.L., Quantin X., Jacot W., Boher J.M., Grenier J., Lamy P.J. Neuroendocrine and cytokeratin serum markers as prognostic determinants of small cell lung cancer. Lung Cancer 2003, 39(2):131-138.
-
(2003)
Lung Cancer
, vol.39
, Issue.2
, pp. 131-138
-
-
Pujol, J.L.1
Quantin, X.2
Jacot, W.3
Boher, J.M.4
Grenier, J.5
Lamy, P.J.6
-
28
-
-
0030016693
-
Serum neuron-specific enolase (S-NSE) and the prognosis in small-cell lung cancer (SCLC): a combined multivariable analysis on data from nine centres
-
Jorgensen L.G., Osterlind K., Genolla J., Gomm S.A., Hernandez J.R., Johnson P.W., et al. Serum neuron-specific enolase (S-NSE) and the prognosis in small-cell lung cancer (SCLC): a combined multivariable analysis on data from nine centres. Br J Cancer 1996, 74(3):463-467.
-
(1996)
Br J Cancer
, vol.74
, Issue.3
, pp. 463-467
-
-
Jorgensen, L.G.1
Osterlind, K.2
Genolla, J.3
Gomm, S.A.4
Hernandez, J.R.5
Johnson, P.W.6
-
29
-
-
67049161492
-
The applicability of the proposed IASLC staging revisions to small cell lung cancer (SCLC) with comparison to the current UICC 6th TNM Edition
-
Ignatius Ou S.H., Zell J.A. The applicability of the proposed IASLC staging revisions to small cell lung cancer (SCLC) with comparison to the current UICC 6th TNM Edition. J Thorac Oncol 2009, 4(3):300-310.
-
(2009)
J Thorac Oncol
, vol.4
, Issue.3
, pp. 300-310
-
-
Ignatius Ou, S.H.1
Zell, J.A.2
-
30
-
-
84899474437
-
Concordance between formalin-fixed paraffin-embedded biopsy samples and surgically resected snap-frozen samples in multiplexed molecular profiling of lung cancers
-
Kenmotsu H., Serizawa M., Koh Y., Isaka M., Takahashi T., Murakami H., et al. Concordance between formalin-fixed paraffin-embedded biopsy samples and surgically resected snap-frozen samples in multiplexed molecular profiling of lung cancers. ASCO Meet Abstr 2013, 31(Suppl. 15):e18556.
-
(2013)
ASCO Meet Abstr
, vol.31
, Issue.SUPPL. 15
-
-
Kenmotsu, H.1
Serizawa, M.2
Koh, Y.3
Isaka, M.4
Takahashi, T.5
Murakami, H.6
-
31
-
-
84899491293
-
Identification of actionable mutations in surgically resected tumor specimens from Japanese patients with non-small cell lung cancer by ultra-deep targeted sequencing
-
Koh Y., Kenmotsu H., Serizawa M., Isaka M., Mori K., Imai H., et al. Identification of actionable mutations in surgically resected tumor specimens from Japanese patients with non-small cell lung cancer by ultra-deep targeted sequencing. ASCO Meet Abstr 2013, 31(Suppl. 15):7572.
-
(2013)
ASCO Meet Abstr
, vol.31
, Issue.SUPPL. 15
, pp. 7572
-
-
Koh, Y.1
Kenmotsu, H.2
Serizawa, M.3
Isaka, M.4
Mori, K.5
Imai, H.6
|