DNA polymerase β deficiency is linked to aggressive breast cancer: A comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts

Molecular Oncology

Volumn 8, Issue 3, 2014, Pages 520-532

  Abdel Fatah, Tarek M A ^a   Russell, Roslin ^b,c   Agarwal, Devika ^d   Moseley, Paul ^a   Abayomi, Michael Ayotunde ^a   Perry, Christina ^a   Albarakati, Nada ^a   Ball, Graham ^d   Chan, Stephen ^a   Caldas, Carlos ^b,c   Ellis, Ian O ^e   Madhusudan, Srinivasan ^a,f  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d NOTTINGHAM TRENT UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^f UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Breast cancer; Pol ; Predictive factor; Prognostic factor

Indexed keywords

ANDROGEN RECEPTOR; BRCA1 PROTEIN; CYTOKERATIN 14; CYTOKERATIN 18; CYTOKERATIN 6; DNA DIRECTED DNA POLYMERASE BETA; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; PROGESTERONE RECEPTOR; PROTEIN; PROTEIN BCL 2; PROTEIN FEN1; PROTEIN P53; PROTEIN SMUG1; PROTEIN TOP2A; TAMOXIFEN; UNCLASSIFIED DRUG; XRCC1 PROTEIN; ESTROGEN RECEPTOR ALPHA, HUMAN; MESSENGER RNA;

ALGORITHM; ARTICLE; ARTIFICIAL NEURAL NETWORK; BASAL LIKE BREAST CANCER; BREAST CANCER; CANCER CELL CULTURE; CANCER GRADING; CANCER PROGNOSIS; CANCER SURVIVAL; CELL DEDIFFERENTIATION; CELLULAR PARAMETERS; CHROMOSOME 8P; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE FREE SURVIVAL; ESTROGEN RECEPTOR NEGATIVE BREAST CANCER; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; FEMALE; GENE DOSAGE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE INTERACTION; GENE LOCUS; GENE PROBE; GENETIC ASSOCIATION; HIGH PROLIFERATION INDEX; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MITOSIS INDEX; PATHOGENESIS; PHENOTYPE; PLEOMORPHISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRIPLE NEGATIVE BREAST CANCER; BREAST; BREAST NEOPLASMS; COHORT ANALYSIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PROGNOSIS;

BREAST; BREAST NEOPLASMS; COHORT STUDIES; DNA POLYMERASE BETA; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE DOSAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PROGNOSIS; RNA, MESSENGER;

EID: 84899490745     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2014.01.001     Document Type: Article

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