GLP-1-related proteins attenuate the effects of mitochondrial membrane damage in pancreatic β cells

Biochemical and Biophysical Research Communications

Volumn 447, Issue 1, 2014, Pages 133-138

  Ogata, Makiko ^a   Iwasaki, Naoko ^a   Ide, Risa ^a   Takizawa, Miho ^a   Uchigata, Yasuko ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

GLP 1; Insulin secretion; Mitochondrial pH

Indexed keywords

CALCIUM ION; ETHIDIUM BROMIDE; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1(7-37); GLUCOSE; LIRAGLUTIDE; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM SIGNALING; CELL DAMAGE; CONTROLLED STUDY; FLUORESCENCE; GLUCOSE TOLERANCE TEST; HUMAN; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; PANCREAS ISLET BETA CELL; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECEPTOR BINDING; STIMULATION;

GLP-1; INSULIN SECRETION; MITOCHONDRIAL PH;

ANIMALS; ETHIDIUM; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; HUMANS; INSULIN-SECRETING CELLS; MITOCHONDRIAL MEMBRANES; PEPTIDE FRAGMENTS; RATS;

EID: 84899487911     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.03.143     Document Type: Article

References (28)

1. J. Holst The physiology of glucagon-like peptide 1 Physiol. Rev. 87 2007 1409 1439
2. L. Baggio, and D. Drucker Biology of incretins: GLP-1 and GIP Gastroenterology 132 2007 2131 2157
3. B. Kreymann, G. Williams, M. Ghatei, and S. Bloom Glucagon-like peptide-1 7-36: a physiological incretin in man Lancet 2 1987 1300 1304
4. S. Mojsov, G. Weir, and J. Habener Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas J. Clin. Invest. 79 1987 616 619
5. S. Ross, J. Brown, and J. Dupré Hypersecretion of gastric inhibitory polypeptide following oral glucose in diabetes mellitus Diabetes 26 1977 525 529
6. M. Nauck, M. Heimesaat, C. Orskov, J. Holst, R. Ebert, and W. Creutzfeldt Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus J. Clin. Invest. 91 1993 301 307
7. T. Vilsbøll, T. Krarup, S. Madsbad, and J.J. Holst Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients Diabetologia 45 2002 1111 1119
8. L. Farilla, A. Bulotta, B. Hirshberg, S. Li Calzi, N. Khoury, H. Noushmehr, C. Bertolotto, U. Di Mario, D. Harlan, and R. Perfetti Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets Endocrinology 144 2003 5149 5158
9. Y. Li, T. Hansotia, B. Yusta, F. Ris, P. Halban, and D. Drucker Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis J. Biol. Chem. 278 2003 471 478
10. Z. Liu, V. Stanojevic, L.J. Brindamour, and J.F. Habener GLP1-derived nonapeptide GLP1(28-36)amide protects pancreatic β-cells from glucolipotoxicity J. Endocrinol. 213 2012 143 154
11. W. Shao, Z. Wang, W. Ip, Y.T. Chiang, X. Xiong, T. Chai, C. Xu, Q. Wang, and T. Jin GLP-1(28-36) improves β-cell mass and glucose disposal in streptozotocin induced diabetes mice and activates PKA-β-catenin signaling in beta-cells in vitro Am. J. Physiol. Endocrinol. Metab. 304 2013 E1263 E1272
12. N. Matikainen, L.H. Bogl, A. Hakkarainen, J. Lundbom, N. Lundbom, J. Kaprio, A. Rissanen, J.J. Holst, and K.H. Pietiläinen GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance Diabetes Care 37 2014 242 251
13. P.A. Antinozzi, H. Ishihara, C.B. Newgard, and C.B. Wollheim Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues J. Biol. Chem. 277 2002 11746 11755
14. M. Ogata, T. Awaji, N. Iwasaki, R. Fujimaki, M. Takizawa, K. Maruyama, Y. Iwamoto, and Y. Uchigata A new mitochondrial pH biosensor for quantitative assessment of pancreatic β-cell function Biochem. Biophys. Res. Commun. 421 2012 20 26
15. E. Zylber, C. Vesco, and S. Penman Selective inhibition of the synthesis of mitochondria-associated RNA by ethidium bromide J. Mol. Biol. 44 1969 195 204
16. H. Fukuhara, and C. Kujawa Selective inhibition of the in vivo transcription of mitochondrial DNA by ethidium bromide and by acriflavin Biochem. Biophys. Res. Commun. 41 1970 1002 1008
17. N. Bastos Rde, and H.R. Mahler Molecular mechanisms of mitochondrial genetic activity. Effects of ethidium bromide on the deoxyribonucleic acid and energetics of isolated mitochondria J. Biol. Chem. 249 1974 6617 6627
18. T. Hayakawa, M. Noda, K. Yasuda, H. Yorifuji, S. Taniguchi, I. Miwa, H. Sakura, Y. Terauchi, J. Hayashi, G.W. Sharp, Y. Kanazawa, Y. Akanuma, Y. Yazaki, and T. Kadowaki Ethidium bromide-induced inhibition of mitochondrial gene transcription suppresses glucose-stimulated insulin release in the mouse pancreatic beta-cell line betaHC9 J. Biol. Chem. 273 1998 20300 20307
19. J. Miyazaki, K. Araki, E. Yamato, H. Ikegami, T. Asano, Y. Shibasaki, Y. Oka, and K. Yamamura Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms Endocrinology 127 1990 126 132
20. S.F. Bode, M. Egg, C. Wallesch, and M. Hermanns-Clausen 10-Fold liraglutide overdose over 7 months resulted only in minor side-effects J. Clin. Pharmacol. 53 2013 785 786
21. R. Nakanishi, T. Hirose, Y. Tamura, Y. Fujitani, and H. Watada Attempted suicide with liraglutide overdose did not induce hypoglycemia Diabetes Res. Clin. Pract. 99 2013 e3 e4
22. C. Kapitza, T. Forst, H.V. Coester, F. Poitiers, P. Ruus, and A. Hincelin-Méry Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on metformin Diabetes Obes. Metab. 15 2013 642 649
23. K. Pabreja, M.A. Mohd, C. Koole, D. Wootten, and S.G. Furness Molecular mechanisms underlying physiological and receptor pleiotropic effects mediated by GLP-1R activation Br. J. Pharmacol. 171 2013 1114 1128
24. Y. Fujita, R.D. Wideman, A. Asadi, G.K. Yang, R. Baker, T. Webber, T. Zhang, R. Wang, Z. Ao, G.L. Warnock, Y.N. Kwok, and T.J. Kieffer Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion Gastroenterology 138 2010 1966 1975
25. G. Kilimnik, A. Kim, D.F. Steiner, T.C. Friedman, and M. Hara Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of β-cell regeneration Islets 2 2010 149 155
26. P. Marchetti, R. Lupi, M. Bugliani, C.L. Kirkpatrick, G. Sebastiani, F.A. Grieco, S. Del Guerra, V. D'Aleo, S. Piro, L. Marselli, U. Boggi, F. Filipponi, L. Tinti, L. Salvini, C.B. Wollheim, F. Purrello, and F. Dotta A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets Diabetologia 55 2012 3262 3272
27. H. Ellingsgaard, I. Hauselmann, B. Schuler, A.M. Habib, L.L. Baggio, D.T. Meier, E. Eppler, K. Bouzakri, S. Wueest, Y.D. Muller, A.M. Hansen, M. Reinecke, D. Konrad, M. Gassmann, F. Reimann, P.A. Halban, J. Gromada, D.J. Drucker, F.M. Gribble, J.A. Ehses, and M.Y. Donath Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells Nat. Med. 17 2011 1481 1489
28. N.M. Whalley, L.E. Pritchard, D.M. Smith, and A. White Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells? J. Endocrinol. 211 2011 99 106