Comprehensive proteomic analysis of white blood cells from chikungunya fever patients of different severities

Journal of Translational Medicine

Volumn 12, Issue 1, 2014, Pages

  Wikan, Nitwara ^a   Khongwichit, Sarawut ^a   Phuklia, Weerawat ^b   Ubol, Sukathida ^a,b   Thonsakulprasert, Tipparat ^c   Thannagith, Montri ^c   Tanramluk, Duangrudee ^a   Paemanee, Atchara ^d   Kittisenachai, Suthathip ^d   Roytrakul, Sittiruk ^d   Smith, Duncan R ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b Department of Microbiology Faculty of Science Mahidol University ^*  (Thailand)

^c Pang Nga Hospital   (Thailand)

^d NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

Author keywords

Caspase 1; Chikungunya; Inflammasome; Proteome

Indexed keywords

INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRUCTURAL PROTEIN; TOLL LIKE RECEPTOR; VIRUS RNA; PRIMER DNA;

ARTICLE; CELL ISOLATION; CHIKUNGUNYA; CONTROLLED STUDY; DISEASE SEVERITY; FUNCTIONAL PROTEOMICS; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LEUKOCYTE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PROTEIN EXPRESSION; THAILAND; VIRUS LOAD; VIRUS PATHOGENESIS; BLOOD; LYMPHOCYTE; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEOMICS; REAL TIME POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY;

BASE SEQUENCE; CHIKUNGUNYA FEVER; CHROMATOGRAPHY, LIQUID; DNA PRIMERS; HUMANS; LYMPHOCYTES; PROTEOMICS; REAL-TIME POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY;

EID: 84899480971     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-12-96     Document Type: Article

References (41)

1. Pialoux G, Gauzere BA, Jaureguiberry S, Strobel M. Chikungunya, an epidemic arbovirosis. Lancet Infect Dis 2007, 7:319-327. 10.1016/S1473-3099(07)70107-X, 17448935.
2. Schwartz O, Albert ML. Biology and pathogenesis of chikungunya virus. Nat Rev Microbiol 2010, 8:491-500. 10.1038/nrmicro2368, 20551973.
3. Powers AM, Brault AC, Tesh RB, Weaver SC. Re-emergence of chikungunya and o'nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships. J Gen Virol 2000, 81:471-479.
4. Pulmanausahakul R, Roytrakul S, Auewarakul P, Smith DR. Chikungunya in Southeast Asia: understanding the emergence and finding solutions. Int J Infect Dis 2011, 15:671-676.
5. Burt FJ, Rolph MS, Rulli NE, Mahalingam S, Heise MT. Chikungunya: a re-emerging virus. Lancet 2012, 379:662-671. 10.1016/S0140-6736(11)60281-X, 22100854.
6. Rezza G, Nicoletti L, Angelini R, Romi R, Finarelli AC, Panning M, Cordioli P, Fortuna C, Boros S, Magurano F, Silvi G, Angelini P, Dottori M, Ciufolini MG, Majori GC, Cassone A, . CHIKV study group Infection with chikungunya virus in Italy: an outbreak in a temperate region. Lancet 2007, 370:1840-1846. 10.1016/S0140-6736(07)61779-6, 18061059, CHIKV study group.
7. Gould EA, Gallian P, De Lamballerie X, Charrel RN. First cases of autochthonous dengue fever and chikungunya fever in France: from bad dream to reality. Clin Microbiol Infect 2010, 16:1702-1704. 10.1111/j.1469-0691.2010.03386.x, 21040155.
8. WHO Chikungunya in the French part of the Caribbean isle of Saint Martin 2013. Global Alert and Response Disease outbreak news 10 December 2013 [internet] 2013, Available from:http://www.who.int/csr/don/2013_12_10a/en/index.html, WHO.
9. Couderc T, Chretien F, Schilte C, Disson O, Brigitte M, Guivel-Benhassine F, Touret Y, Barau G, Cayet N, Schuffenecker I, Desprès P, Arenzana-Seisdedos F, Michault A, Albert ML, Lecuit M. A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease. PLoS Pathog 2008, 4:e29. 10.1371/journal.ppat.0040029, 2242832, 18282093.
10. Ozden S, Huerre M, Riviere JP, Coffey LL, Afonso PV, Mouly V, de Monredon J, Roger JC, El Amrani M, Yvin JL, Jaffar MC, Frenkiel MP, Sourisseau M, Schwartz O, Butler-Browne G, Desprès P, Gessain A, Ceccaldi PE. Human muscle satellite cells as targets of Chikungunya virus infection. PLoS One 2007, 2:e527. 10.1371/journal.pone.0000527, 1885285, 17565380.
11. Hoarau JJ, Jaffar Bandjee MC, Krejbich Trotot P, Das T, Li-Pat-Yuen G, Dassa B, Denizot M, Guichard E, Ribera A, Henni T, Tallet F, Moiton MP, Gauzère BA, Bruniquet S, Jaffar Bandjee Z, Morbidelli P, Martigny G, Jolivet M, Gay F, Grandadam M, Tolou H, Vieillard V, Debré P, Autran B, Gasque P. Persistent chronic inflammation and infection by Chikungunya arthritogenic alphavirus in spite of a robust host immune response. J Immunol 2010, 184:5914-5927. 10.4049/jimmunol.0900255, 20404278.
12. Her Z, Malleret B, Chan M, Ong EK, Wong SC, Kwek DJ, Tolou H, Lin RT, Tambyah PA, Renia L, Ng LF. Active infection of human blood monocytes by Chikungunya virus triggers an innate immune response. J Immunol 2010, 184:5903-5913. 10.4049/jimmunol.0904181, 20404274.
13. Labadie K, Larcher T, Joubert C, Mannioui A, Delache B, Brochard P, Guigand L, Dubreil L, Lebon P, Verrier B, Verrier B, de Lamballerie X, Suhrbier A, Cherel Y, Le Grand R, Roques P. Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages. J Clin Invest 2010, 120:894-906. 10.1172/JCI40104, 2827953, 20179353.
14. Wintachai P, Wikan N, Kuadkitkan A, Jaimipuk T, Ubol S, Pulmanausahakul R, Auewarakul P, Kasinrerk W, Weng WY, Panyasrivanit M, Paemanee A, Kittisenachai S, Roytrakul S, Smith DR. Identification of prohibitin as a Chikungunya virus receptor protein. J Med Virol 2012, 84:1757-1770. 10.1002/jmv.23403, 22997079.
15. Bernard E, Solignat M, Gay B, Chazal N, Higgs S, Devaux C, Briant L. Endocytosis of chikungunya virus into mammalian cells: role of clathrin and early endosomal compartments. PLoS One 2010, 5:e11479. 10.1371/journal.pone.0011479, 2900206, 20628602.
16. Krejbich-Trotot P, Denizot M, Hoarau JJ, Jaffar-Bandjee MC, Das T, Gasque P. Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses. Virol J 2011, 25:314-325.
17. Sourisseau M, Schilte C, Casartelli N, Trouillet C, Guivel-Benhassine F, Rudnicka D, Sol-Foulon N, Le Roux K, Prevost MC, Fsihi H, Frenkiel MP, Blanchet F, Afonso PV, Ceccaldi PE, Ozden S, Gessain A, Schuffenecker I, Verhasselt B, Zamborlini A, Saïb A, Rey FA, Arenzana-Seisdedos F, Desprès P, Michault A, Albert ML, Schwartz O. Characterization of reemerging chikungunya virus. PLoS Pathog 2007, 3:e89. 10.1371/journal.ppat.0030089, 1904475, 17604450.
18. Wikan N, Sakoonwatanyoo P, Ubol S, Yoksan S, Smith DR. Chikungunya virus infection of cell lines: analysis of the East, central and South african lineage. PLoS One 2012, 7:e31102. 10.1371/journal.pone.0031102, 3267766, 22299053.
19. Joubert PE, Werneke SW, de la Calle C, Guivel-Benhassine F, Giodini A, Peduto L, Levine B, Schwartz O, Lenschow DJ, Albert ML. Chikungunya virus-induced autophagy delays caspase-dependent cell death. J Exp Med 2012, 209:1029-1047. 10.1084/jem.20110996, 3348111, 22508836.
20. Judith D, Mostowy S, Bourai M, Gangneux N, Lelek M, Lucas-Hourani M, Cayet N, Jacob Y, Prevost MC, Pierre P, Tangy F, Zimmer C, Vidalain PO, Couderc T, Lecuit M. Species-specific impact of the autophagy machinery on Chikungunya virus infection. EMBO Rep 2013, 14:534-544. 10.1038/embor.2013.51, 23619093.
21. Krejbich-Trotot P, Gay B, Li-Pat-Yuen G, Hoarau JJ, Jaffar-Bandjee MC, Briant L, Gasque P, Denizot M. Chikungunya triggers an autophagic process which promotes viral replication. Virol J 2011, 8:432. 10.1186/1743-422X-8-432, 3179960, 21902836.
22. Lee YR, Lei HY, Liu MT, Wang JR, Chen SH, Jiang-Shieh YF, Lin YS, Yeh TM, Liu CC, Liu HS. Autophagic machinery activated by dengue virus enhances virus replication. Virology 2008, 374:240-248. 10.1016/j.virol.2008.02.016, 18353420.
23. Panyasrivanit M, Khakpoor A, Wikan N, Smith DR. Co-localization of constituents of the dengue virus translation and replication machinery with amphisomes. J Gen Virol 2009, 90:448-456. 10.1099/vir.0.005355-0, 19141455.
24. Abere B, Wikan N, Ubol S, Auewarakul P, Paemanee A, Kittisenachai S, Roytrakul S, Smith DR. Proteomic analysis of chikungunya virus infected microgial cells. PLoS One 2012, 7:e34800. 10.1371/journal.pone.0034800, 3326055, 22514668.
25. Dhanwani R, Khan M, Alam SI, Rao PV, Parida M. Differential proteome analysis of Chikungunya virus-infected new-born mice tissues reveal implication of stress, inflammatory and apoptotic pathways in disease pathogenesis. Proteomics 2011, 11:1936-1951. 10.1002/pmic.201000500, 21472854.
26. Thio CL, Yusof R, Abdul-Rahman PS, Karsani SA. Differential proteome analysis of chikungunya virus infection on host cells. PLoS One 2013, 8:e61444. 10.1371/journal.pone.0061444, 3622599, 23593481.
27. Lohachanakul J, Phuklia W, Thannagith M, Thonsakulprasert T, Ubol S. High concentrations of circulating interleukin-6 and monocyte chemotactic protein-1 with low concentrations of interleukin-8 were associated with severe chikungunya fever during the 2009-2010 outbreak in Thailand. Microbiol Immunol 2012, 56:134-138. 10.1111/j.1348-0421.2011.00417.x, 22188545.
28. Garmashova N, Gorchakov R, Volkova E, Paessler S, Frolova E, Frolov I. The Old World and New World alphaviruses use different virus-specific proteins for induction of transcriptional shutoff. J Virol 2007, 81:2472-2484. 10.1128/JVI.02073-06, 1865960, 17108023.
29. White LK, Sali T, Alvarado D, Gatti E, Pierre P, Streblow D, Defilippis VR. Chikungunya virus induces IPS-1-dependent innate immune activation and proteinkinase R-independent translational shutoff. J Virol 2011, 85:606-620. 10.1128/JVI.00767-10, 3014158, 20962078.
30. Bhatia VN, Perlman DH, Costello CE, McComb ME. Software tool for researching annotations of proteins: open-source protein annotation software with data visualization. Anal Chem 2009, 81:9819-9823. 10.1021/ac901335x, 2787672, 19839595.
31. Appenheimer MM, Chen Q, Girard RA, Wang WC, Evans SS. Impact of fever-range thermal stress on lymphocyte-endothelial adhesion and lymphocyte trafficking. Immunol Invest 2005, 34:295-323. 10.1081/IMM-200064501, 16136783.
32. Kroeker AL, Ezzati P, Coombsk KM, Halayko AJ. Influenza A infection of primary human airway epithelial cells up-regulates proteins related to purine metabolism and ubiquitin-related signaling. J Proteome Res 2013, 12:3139-3151. 10.1021/pr400464p, 23750822.
33. Brostrom CO, Brostrom MA. Calcium-dependent regulation of protein synthesis in intact mammalian cells. Annu Rev Physiol 1990, 52:577-590. 10.1146/annurev.ph.52.030190.003045, 2184768.
34. Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002, 296:1655-1657. 10.1126/science.296.5573.1655, 12040186.
35. Makela SM, Strengell M, Pietila TE, Osterlund P, Julkunen I. Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells. J Leukoc Biol 2009, 85:664-672. 10.1189/jlb.0808503, 19164128.
36. Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004, 5:987-995. 10.1038/ni1112, 15454922.
37. Bowie AG, Haga IR. The role of Toll-like receptors in the host response to viruses. Mol Immunol 2005, 42:859-867. 10.1016/j.molimm.2004.11.007, 15829275.
38. Mogensen TH, Paludan SR. Reading the viral signature by Toll-like receptors and other pattern recognition receptors. J Mol Med (Berl) 2005, 83:180-192. 10.1007/s00109-004-0620-6, 15635478.
39. Osawa R, Williams KL, Singh N. The inflammasome regulatory pathway and infections: role in pathophysiology and clinical implications. J Infect 2011, 62:119-129. 10.1016/j.jinf.2010.10.002, 20950647.
40. Ng LF, Chow A, Sun YJ, Kwek DJ, Lim PL, Dimatatac F, Ng LC, Ooi EE, Choo KH, Her Z, Kourilsky P, Leo YS. IL-1beta, IL-6, and RANTES as biomarkers of Chikungunya severity. PLoS One 2009, 4:e4261. 10.1371/journal.pone.0004261, 2625438, 19156204.
41. Krzywinski M, Altman N. Significance, P values and t-tests. Nat Methods 2013, 10:1041-1042. 10.1038/nmeth.2698, 24344377.