Stabilization of circulating tumor cells in blood using a collection device with a preservative reagent

Cancer Cell International

Volumn 14, Issue 1, 2014, Pages

  Qin, Jianbing ^a   Alt, Jodi R ^a   Hunsley, Bradford A ^a   Williams, Thomas L ^b   Fernando, M R ^a  

^a Streck Inc   (United States)

^b Methodist Hospital   (United States)

Author keywords

Blood collection devices; Circulating tumor cells; Clinical laboratory techniques

Indexed keywords

CYCLIN D1; CYTOKERATIN; EDETIC ACID; EPITHELIAL CELL ADHESION MOLECULE; MESSENGER RNA; PRESERVATIVE; REAGENT; FORMALDEHYDE; NUCLEIC ACID; PROTEIN;

ARTICLE; BLOOD COLLECTION TUBE; BLOOD SAMPLING; BLOOD STORAGE; BREAST CANCER; CANCER CELL; CANCER DIAGNOSIS; CANCER PROGNOSIS; CELL FREE SYSTEM; CELL STRAIN MCF 7; CIRCULATING TUMOR CELL; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; FLUORESCENCE; GENE AMPLIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MOLECULAR BEACON; PHLEBOTOMY; PROTEIN STABILITY; ROOM TEMPERATURE; ADULT; ARTERIAL BLOOD SAMPLING KIT; BLOOD DONOR; BREAST CANCER CELL LINE; CANCER PATIENT; CELL ISOLATION; DEVICE COMPARISON; MCF 7 CELL LINE; MOLECULAR STABILITY; NORMAL HUMAN; ONCOGENE C FOS; PROTEIN EXPRESSION; TRAFFIC AND TRANSPORT;

EID: 84899477466     PISSN: None     EISSN: 14752867     Source Type: Journal    
DOI: 10.1186/1475-2867-14-23     Document Type: Article

References (27)

1. Ring A, Smith IE, Dowsett M. Circulating tumor cells in breast cancer. Lancet 2004, 5:79-88.
2. Ashworth TR. A case of cancer in which cells similar to those in the tumors were seen in the blood after death. Aust Med J 1869, 14:146-149.
3. Cristofanilli M, Budd GT, Ellis MJ, Stopeck A, Matera J, Miller MC, Reuben JM, Doyle GV, Allard WJ, Terstappen LW, Hayes DF. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. New Engl J Med 2004, 91:781-791.
4. Fehm T, Solomayer EF, Meng S, Tucker T, Lane N, Wang J, Gebauer G. Methods for isolating circulating epithelial cells and criteria for their classification as carcinoma cells. Cytotherapy 2005, 7:171-185. 10.1080/14653240510027082, 16040397.
5. Tibbe AG, Miller MC, Terstappen LW. Statistical considerations for enumeration of circulating tumor cells. Cytometry A 2007, 71:154-162.
6. Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, Ulkus L, Smith MR, Kwak EL, Digumarthy S, Muzikansky A, Ryan P, Balis UJ, Tompkins RG, Haber DA, Toner M. Isolation of rare circulating tumor cells in cancer patients by microchip technology. Nature 2007, 450:1235-1239. 10.1038/nature06385, 3090667, 18097410.
7. Dong X, Alpaugh RK, Cristofanilli M. Circulating tumor cells (CTCs) in breast cancer: a diagnostic tool for prognosis and molecular analysis. Chin J Cancer Res 2012, 24:388-98. 10.1007/s11670-012-0279-4, 3551332, 23359451.
8. Deng G, Herrler M, Burgess D, Manna E, Krag D, Burke JF. Enrichment with anti-cytokeratin alone or combined with anti-EpCAM antibodies significantly increases the sensitivity for circulating tumor cell detection in metastatic breast cancer patients. Breast Cancer Res 2008, 10:2131-2141.
9. Allard WJ, Matera J, Miller MC, Repollet M, Connelly MC, Rao C, Tibbe AG, Uhr JW, Terstappen LW. Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant disease. Clin Cancer Res 2004, 10:6897-6904. 10.1158/1078-0432.CCR-04-0378, 15501967.
10. Meng S, Tripathy D, Frenkel EP, Shete S, Naftalis EZ, Huth JF, Beitsch PD, Leitch M, Hoover S, Euhus D, Haley B, Morrison L, Fleming TP, Herlyn D, Terstappen LW, Fehm T, Tucker TF, Lane N, Wang J, Uhr JW. Circulating tumor cells in patients with breast cancer dormancy. Clin Cancer Res 2004, 10:8152-8162. 10.1158/1078-0432.CCR-04-1110, 15623589.
11. Smerage JB, Doyle GV, Budd GT, Schott AF, Blayney DW, Wicha MS, Repollet M, Terstappen LWMM, Hayes DF. The detection of apoptosis and Bcl-2 expression in circulating tumor cells (CTCs) from women being treated for metastatic breast cancer [abstract]. Proc Am Assoc Cancer Res 2006, 47:#792.
12. Riethdorf S, Fritsche H, Müller V, Rau T, Schindlbeck C, Rack B, Janni W, Coith C, Beck K, Jänicke F, Jackson S, Gornet T, Cristofanilli M, Pantel K. Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the cell search system. Clin Cancer Res 2007, 13:920-928. 10.1158/1078-0432.CCR-06-1695, 17289886.
13. Lianidou ES, Markou A. Circulating tumor cells in breast cancer: detection systems, molecular characterizations, and future challenges. Clin Chem 2011, 57:1242-1255. 10.1373/clinchem.2011.165068, 21784769.
14. Das K, Dumais J, Basiaga S, Krzyzanowski GD. Carbon-13 nuclear magnetic resonance analyses of formaldehyde free preservatives. Acta Histochem 2013, 115:481-6. 10.1016/j.acthis.2012.11.004, 23261251.
15. Fernando MR, Chen K, Norton S, Krzyzanowski G, Bourne D, Hunsley B, Ryan WL, Bassett C. A new methodology to preserve the original proportion and integrity of cell-free fetal DNA in maternal plasma during sample processing and storage. Prenat Diagn 2010, 30:418-424.
16. Norton SE, Luna KK, Lechner JM, Qin J, Fernando MR. A new blood collection device minimizes cellular DNA release during sample storage and shipping when compared to a standard device. J Clin Lab Anal 2013, 27:305-311. 10.1002/jcla.21603, 3748785, 23852790.
17. Norton SE, Lechner JM, William T, Fernando MR. A stabilizing reagent prevents cell-free DNA contamination by cellular DNA in plasma during blood sample storage and shipping as determined by digital PCR. J Clin Biochem 2013, in press.
18. Hayes DF, Smerage J. Is there a role for circulating tumor cells in the management of breast cancer?. Clin Cancer Res 2008, 14:3646-3650. 10.1158/1078-0432.CCR-07-4481, 18559576.
19. de Bono JS, Scher HI, Montgomery RB, Parker C, Miller MC, Tissing H, Doyle GV, Terstappen LW, Pienta KJ, Raghavan D. Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin Cancer Res 2008, 14:6302-6309. 10.1158/1078-0432.CCR-08-0872, 18829513.
20. Cohen SJ, Punt CJ, Iannotti N, Saidman BH, Sabbath KD, Gabrail NY, Picus J, Morse M, Mitchell E, Miller MC, Doyle GV, Tissing H, Terstappen LW, Meropol NJ. Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer. J Clin Oncol 2008, 26:3213-3221. 10.1200/JCO.2007.15.8923, 18591556.
21. Naoe M, Ogawa Y, Morita J, Omori K, Takeshita K, Shichijyo T, Okumura T, Igarashi A, Yanaihara A, Iwamoto S, Fukagai T, Miyazaki A, Yoshida H. Detection of circulating urothelial cancer cells in the blood using the cell search system. Cancer 2007, 109:1439-1445. 10.1002/cncr.22543, 17326057.
22. Okumura Y, Tanaka F, Yoneda K, Hashimoto M, Takuwa T, Kondo N, Hasegawa S. Circulating tumor cells in pulmonary venous blood of primary lung cancer patients. Ann Thorac Surg 2009, 87:1669-1675. 10.1016/j.athoracsur.2009.03.073, 19463575.
23. Steen S, Nemunaitis J, Fisher T, Kuhn J. Circulating tumor cells in melanoma: a review of the literature and description of a novel technique. Proc (Bayl Univ Med Cent) 2008, 21:127-132. 2277345, 18382750.
24. Parkinson DR, Dracopoli N, Petty BG, Compton C, Cristofanilli M, Deisseroth A, Hayes DF, Kapke G, Kumar P, Lee JS, Liu MC, McCormack R, Mikulski S, Nagahara L, Pantel K, Pearson-White S, Punnoose EA, Roadcap LT, Schade AE, Scher HI, Sigman CC, Kelloff GJ. Considerations in the development of circulatingtumor cell technology for clinical use. J Transl Med 2012, 10:138-148. 10.1186/1479-5876-10-138, 3478228, 22747748.
25. Sieuwerts AM, Kraan J, Bolt J, van der Spoel P, Elstrodt F, Schutte M, Martens JW, Gratama JW, Sleijfer S, Foekens JA. Anti-epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells. J Natl Cancer Inst 2009, 101:61-66. 10.1093/jnci/djn419, 2639293, 19116383.
26. Srinivasan M, Sedmak D, Jewell S. Effect of fixatives and tissue processing on the content and integrity of nucleic acids. Am J Pathol 2002, 161:1961-1971. 10.1016/S0002-9440(10)64472-0, 1850907, 12466110.
27. Das K, Wigginton S, Basiaga S, Williams T, Fernando MR. Effects of a novel cell stabilizing reagent on DNA amplification by PCR as compared to traditional stabilizing reagents. Acta Histochem 2014, 116:55-60. 10.1016/j.acthis.2013.05.002, 23810682.