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Volumn 55, Issue 3, 2014, Pages 500-507

Development of 124I immuno-pet targeting tumor vascular TEM1/endosialin

Author keywords

Endosialin; Immuno PET; Monoclonal antibodies; MORAb 004; TEM1

Indexed keywords

ENDOSIALIN; EPITOPE; MORAB 004; MORAB 004 I 124; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; LEUKOCYTE ANTIGEN; MONOCLONAL ANTIBODY; RADIOACTIVE IODINE; TUMOR ENDOTHELIAL MARKER 1, MOUSE; TUMOR PROTEIN;

EID: 84899473099     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.113.121905     Document Type: Article
Times cited : (30)

References (38)
  • 1
    • 0034682892 scopus 로고    scopus 로고
    • Genes expressed in human tumor endothelium
    • St. Croix B, Rago C, Velculescu V, et al. Genes expressed in human tumor endothelium. Science. 2000;289:1197-1202.
    • (2000) Science. , vol.289 , pp. 1197-1202
    • St. Croix, B.1    Rago, C.2    Velculescu, V.3
  • 4
    • 0026469991 scopus 로고
    • Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer
    • Rettig WJ, Garin-Chesa P, Healey JH, Su SL, Jaffe EA, Old LJ. Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer. Proc Natl Acad Sci USA. 1992;89:10832-10836.
    • (1992) Proc Natl Acad Sci USA. , vol.89 , pp. 10832-10836
    • Rettig, W.J.1    Garin-Chesa, P.2    Healey, J.H.3    Su, S.L.4    Jaffe, E.A.5    Old, L.J.6
  • 5
    • 0035831506 scopus 로고    scopus 로고
    • Molecular cloning and characterization of endosialin, a c-type lectin-like cell surface receptor of tumor endothelium
    • Christian S, Ahorn H, Koehler A, et al. Molecular cloning and characterization of endosialin, a C-type lectin-like cell surface receptor of tumor endothelium. J Biol Chem. 2001;276:7408-7414.
    • (2001) J Biol Chem. , vol.276 , pp. 7408-7414
    • Christian, S.1    Ahorn, H.2    Koehler, A.3
  • 6
    • 58149343911 scopus 로고    scopus 로고
    • Endosialin protein expression and therapeutic target potential in human solid tumors: Sarcoma versus carcinoma
    • Rouleau C, Curiel M, Weber W, et al. Endosialin protein expression and therapeutic target potential in human solid tumors: sarcoma versus carcinoma. Clin Cancer Res. 2008;14:7223-7236.
    • (2008) Clin Cancer Res. , vol.14 , pp. 7223-7236
    • Rouleau, C.1    Curiel, M.2    Weber, W.3
  • 8
    • 39549089088 scopus 로고    scopus 로고
    • Endosialin (tem1) is a marker of tumorassociated myofibroblasts and tumor vessel-associated mural cells
    • Christian S, Winkler R, Helfrich I, et al. Endosialin (Tem1) is a marker of tumorassociated myofibroblasts and tumor vessel-associated mural cells. Am J Pathol. 2008;172:486-494.
    • (2008) Am J Pathol. , vol.172 , pp. 486-494
    • Christian, S.1    Winkler, R.2    Helfrich, I.3
  • 9
    • 70450225616 scopus 로고    scopus 로고
    • Endosialin: From vascular target to biomarker for human sarcomas
    • Bagley RG. Endosialin: from vascular target to biomarker for human sarcomas. Biomark Med. 2009;3:589-604.
    • (2009) Biomark Med. , vol.3 , pp. 589-604
    • Bagley, R.G.1
  • 10
    • 1642333026 scopus 로고    scopus 로고
    • Levels of expression of endothelial markers specific to tumour-associated endothelial cells and their correlation with prognosis in patients with breast cancer
    • Davies G, Cunnick GH, Mansel RE, Mason MD, Jiang WG. Levels of expression of endothelial markers specific to tumour-associated endothelial cells and their correlation with prognosis in patients with breast cancer. Clin Exp Metastasis. 2004;21:31-37.
    • (2004) Clin Exp Metastasis. , vol.21 , pp. 31-37
    • Davies, G.1    Cunnick, G.H.2    Mansel, R.E.3    Mason, M.D.4    Jiang, W.G.5
  • 11
    • 34047249773 scopus 로고    scopus 로고
    • Newer vascular targets: Endosialin
    • Teicher BA. Newer vascular targets: endosialin. Int J Oncol. 2007;30:305-312.
    • (2007) Int J Oncol. , vol.30 , pp. 305-312
    • Teicher, B.A.1
  • 12
    • 84857135316 scopus 로고    scopus 로고
    • Cd248: Reviewing its role in health and disease
    • Valdez Y, Maia M, Conway EM. CD248: reviewing its role in health and disease. Curr Drug Targets. 2012;13:432-439.
    • (2012) Curr Drug Targets. , vol.13 , pp. 432-439
    • Valdez, Y.1    Maia, M.2    Conway, E.M.3
  • 13
    • 72549107748 scopus 로고    scopus 로고
    • Characterization of tem1/ endosialin in human and murine brain tumors
    • Carson-Walter EB, Winans BN, Whiteman MC, et al. Characterization of TEM1/ endosialin in human and murine brain tumors. BMC Cancer. 2009;9:417.
    • (2009) BMC Cancer. , vol.9 , pp. 417
    • Carson-Walter, E.B.1    Winans, B.N.2    Whiteman, M.C.3
  • 14
    • 15844403827 scopus 로고    scopus 로고
    • Prognostic values of tumor endothelial markers in patients with colorectal cancer
    • Rmali KA, Puntis MC, Jiang WG. Prognostic values of tumor endothelial markers in patients with colorectal cancer. World J Gastroenterol. 2005;11:1283-1286.
    • (2005) World J Gastroenterol. , vol.11 , pp. 1283-1286
    • Rmali, K.A.1    Puntis, M.C.2    Jiang, W.G.3
  • 15
    • 23744458987 scopus 로고    scopus 로고
    • Characterization of cancer stroma markers: In silico analysis of an mrna expression database for fibroblast activation protein and endosialin
    • Dolznig H, Schweifer N, Puri C, et al. Characterization of cancer stroma markers: in silico analysis of an mRNA expression database for fibroblast activation protein and endosialin. Cancer Immun. 2005;5:10.
    • (2005) Cancer Immun. , vol.5 , pp. 10
    • Dolznig, H.1    Schweifer, N.2    Puri, C.3
  • 16
    • 0035914327 scopus 로고    scopus 로고
    • Molecular characterization of the mouse tem1/endosialin gene regulated by cell density in vitro and expressed in normal tissues in vivo
    • Opavsky R, Haviernik P, Jurkovicova D, et al. Molecular characterization of the mouse Tem1/endosialin gene regulated by cell density in vitro and expressed in normal tissues in vivo. J Biol Chem. 2001;276:38795-38807.
    • (2001) J Biol Chem. , vol.276 , pp. 38795-38807
    • Opavsky, R.1    Haviernik, P.2    Jurkovicova, D.3
  • 17
    • 78650003611 scopus 로고    scopus 로고
    • Rapid isolation of high-affinity human antibodies against the tumor vascular marker endosialin/ tem1, using a paired yeast-display/secretory scfv library platform
    • Zhao A, Nunez-Cruz S, Li C, Coukos G, Siegel DL, Scholler N. Rapid isolation of high-affinity human antibodies against the tumor vascular marker Endosialin/ TEM1, using a paired yeast-display/secretory scFv library platform. J Immunol Methods. 2011;363:221-232.
    • (2011) J Immunol Methods. , vol.363 , pp. 221-232
    • Zhao, A.1    Nunez-Cruz, S.2    Li, C.3    Coukos, G.4    Siegel, D.L.5    Scholler, N.6
  • 19
    • 33646062270 scopus 로고    scopus 로고
    • Isolation and characterization of a scfv antibody specific for tumor endothelial marker 1 (tem1), a new reagent for targeted tumor therapy
    • Marty C, Langer-Machova Z, Sigrist S, Schott H, Schwendener RA, Ballmer- Hofer K. Isolation and characterization of a scFv antibody specific for tumor endothelial marker 1 (TEM1), a new reagent for targeted tumor therapy. Cancer Lett. 2006;235:298-308.
    • (2006) Cancer Lett. , vol.235 , pp. 298-308
    • Marty, C.1    Langer-Machova, Z.2    Sigrist, S.3    Schott, H.4    Schwendener, R.A.5    Ballmer- Hofer, K.6
  • 20
    • 36749080458 scopus 로고    scopus 로고
    • Interaction of endosialin/tem1 with extracellular matrix proteins mediates cell adhesion and migration
    • Tomkowicz B, Rybinski K, Foley B, et al. Interaction of endosialin/TEM1 with extracellular matrix proteins mediates cell adhesion and migration. Proc Natl Acad Sci USA. 2007;104:17965-17970.
    • (2007) Proc Natl Acad Sci USA. , vol.104 , pp. 17965-17970
    • Tomkowicz, B.1    Rybinski, K.2    Foley, B.3
  • 22
    • 48749115804 scopus 로고    scopus 로고
    • Tumor stroma marker endosialin (tem1) is a binding partner of metastasis-related protein mac-2 bp/90k
    • Becker R, Lenter MC, Vollkommer T, et al. Tumor stroma marker endosialin (Tem1) is a binding partner of metastasis-related protein Mac-2 BP/90K. FASEB J. 2008;22:3059-3067.
    • (2008) FASEB J. , vol.22 , pp. 3059-3067
    • Becker, R.1    Lenter, M.C.2    Vollkommer, T.3
  • 23
    • 10044261901 scopus 로고    scopus 로고
    • Human endosialin (tumor endothelial marker 1) is abundantly expressed in highly malignant and invasive brain tumors
    • Brady J, Neal J, Sadakar N, Gasque P. Human endosialin (tumor endothelial marker 1) is abundantly expressed in highly malignant and invasive brain tumors. J Neuropathol Exp Neurol. 2004;63:1274-1283.
    • (2004) J Neuropathol Exp Neurol. , vol.63 , pp. 1274-1283
    • Brady, J.1    Neal, J.2    Sadakar, N.3    Gasque, P.4
  • 24
    • 20944451492 scopus 로고    scopus 로고
    • Endosialin (tem1, cd248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium
    • MacFadyen JR, Haworth O, Roberston D, et al. Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium. FEBS Lett. 2005;579:2569-2575.
    • (2005) FEBS Lett. , vol.579 , pp. 2569-2575
    • MacFadyen, J.R.1    Haworth, O.2    Roberston, D.3
  • 25
    • 33947504376 scopus 로고    scopus 로고
    • Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric g250 (124i-cg250) and pet in patients with renal masses: A phase i trial
    • Divgi CR, Pandit-Taskar N, Jungbluth AA, et al. Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: a phase I trial. Lancet Oncol. 2007;8:304-310.
    • (2007) Lancet Oncol. , vol.8 , pp. 304-310
    • Divgi, C.R.1    Pandit-Taskar, N.2    Jungbluth, A.A.3
  • 26
    • 19944430279 scopus 로고    scopus 로고
    • Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain fv-fc antibody fragments
    • Kenanova V, Olafsen T, Crow DM, et al. Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments. Cancer Res. 2005;65:622-631.
    • (2005) Cancer Res. , vol.65 , pp. 622-631
    • Kenanova, V.1    Olafsen, T.2    Crow, D.M.3
  • 27
    • 1542681650 scopus 로고    scopus 로고
    • 124I-labeled Engineered Anti-CEA Minibodies And Diabodies Allow High-contrast Antigen-specific Small-animal PET Imaging Of Xenografts In Athymic Mice
    • Sundaresan G, Yazaki PJ, Shively JE, et al. 124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice. J Nucl Med. 2003;44:1962-1969.
    • (2003) J Nucl Med. , vol.44 , pp. 1962-1969
    • Sundaresan, G.1    Yazaki, P.J.2    Shively, J.E.3
  • 28
    • 0347416983 scopus 로고    scopus 로고
    • Protein kinase c delta is activated in mouse ovarian surface epithelial cancer cells by 2, 3, 78-tetrachlorodibenzo-p-dioxin (tcdd)
    • Williams SR, Son DS, Terranova PF. Protein kinase C delta is activated in mouse ovarian surface epithelial cancer cells by 2,3,7,8-tetrachlorodibenzo-p- dioxin (TCDD). Toxicology. 2004;195:1-17.
    • (2004) Toxicology , vol.195 , pp. 1-17
    • Williams, S.R.1    Son, D.S.2    Terranova, P.F.3
  • 29
    • 80053598654 scopus 로고    scopus 로고
    • The iodogen method for radiolabeling protein
    • In: Walker JM, ed. Totowa, NJ: Humana Press, Inc
    • Bailey G. The Iodogen method for radiolabeling protein. In: Walker JM, ed. The Protein Protocols Handbook. Totowa, NJ: Humana Press, Inc.; 1996:673-674.
    • (1996) The Protein Protocols Handbook. , pp. 673-674
    • Bailey, G.1
  • 30
    • 84859734242 scopus 로고    scopus 로고
    • Collaborative enhancement of antibody binding to distinct pecam-1 epitopes modulates endothelial targeting
    • Chacko AM, Nayak M, Greineder CF, Delisser HM, Muzykantov VR. Collaborative enhancement of antibody binding to distinct PECAM-1 epitopes modulates endothelial targeting. PLoS ONE. 2012;7:e34958.
    • (2012) PLoS ONE. , vol.7
    • Chacko, A.M.1    Nayak, M.2    Greineder, C.F.3    Delisser, H.M.4    Muzykantov, V.R.5
  • 31
    • 23744467260 scopus 로고    scopus 로고
    • Imaging performance of a-pet: A small animal pet camera
    • Surti S, Karp JS, Perkins AE, et al. Imaging performance of A-PET: a small animal PET camera. IEEE Trans Med Imaging. 2005;24:844-852.
    • (2005) IEEE Trans Med Imaging. , vol.24 , pp. 844-852
    • Surti, S.1    Karp, J.S.2    Perkins, A.E.3
  • 32
    • 53649100092 scopus 로고    scopus 로고
    • Endosialin/tem 1/cd248 is a pericyte marker of embryonic and tumor neovascularization
    • Bagley RG, Honma N, Weber W, et al. Endosialin/TEM 1/CD248 is a pericyte marker of embryonic and tumor neovascularization. Microvasc Res. 2008;76: 180-188.
    • (2008) Microvasc Res. , vol.76 , pp. 180-188
    • Bagley, R.G.1    Honma, N.2    Weber, W.3
  • 33
    • 53349173701 scopus 로고    scopus 로고
    • Human endothelial precursor cells express tumor endothelial marker 1/endosialin/cd248
    • Bagley RG, Rouleau C, St Martin T, et al. Human endothelial precursor cells express tumor endothelial marker 1/endosialin/CD248. Mol Cancer Ther. 2008;7:2536-2546.
    • (2008) Mol Cancer Ther. , vol.7 , pp. 2536-2546
    • Bagley, R.G.1    Rouleau, C.2    St Martin, T.3
  • 34
    • 79954591401 scopus 로고    scopus 로고
    • Correlation of in vivo and in vitro measures of carbonic anhydrase ix antigen expression in renal masses using antibody 124i-cg250
    • Pryma DA, O'Donoghue JA, Humm JL, et al. Correlation of in vivo and in vitro measures of carbonic anhydrase IX antigen expression in renal masses using antibody 124I-cG250. J Nucl Med. 2011;52:535-540.
    • (2011) J Nucl Med. , vol.52 , pp. 535-540
    • Pryma, D.A.1    O'Donoghue, J.A.2    Humm, J.L.3
  • 35
    • 83755168354 scopus 로고    scopus 로고
    • 124I-huA33 Antibody Uptake Is Driven By A33 Antigen Concentration In Tissues From Colorectal Cancer Patients Imaged By Immuno-PET
    • O'Donoghue JA, Smith-Jones PM, Humm JL, et al. 124I-huA33 antibody uptake is driven by A33 antigen concentration in tissues from colorectal cancer patients imaged by immuno-PET. J Nucl Med. 2011;52:1878-1885.
    • (2011) J Nucl Med. , vol.52 , pp. 1878-1885
    • O'Donoghue, J.A.1    Smith-Jones, P.M.2    Humm, J.L.3
  • 36
    • 73349092778 scopus 로고    scopus 로고
    • Noninternalizing monoclonal antibodies are suitable candidates for 125i radioimmunotherapy of small-volume peritoneal carcinomatosis
    • Santoro L, Boutaleb S, Garambois V, et al. Noninternalizing monoclonal antibodies are suitable candidates for 125I radioimmunotherapy of small-volume peritoneal carcinomatosis. J Nucl Med. 2009;50:2033-2041.
    • (2009) J Nucl Med. , vol.50 , pp. 2033-2041
    • Santoro, L.1    Boutaleb, S.2    Garambois, V.3
  • 37
    • 0029041918 scopus 로고
    • Early and extensive contribution of pericytes/vascular smooth muscle cells to microvascular proliferation in glioblastoma multiforme: An immuno-light and immunoelectron microscopic study
    • Wesseling P, Schlingemann RO, Rietveld FJ, Link M, Burger PC, Ruiter DJ. Early and extensive contribution of pericytes/vascular smooth muscle cells to microvascular proliferation in glioblastoma multiforme: an immuno-light and immunoelectron microscopic study. J Neuropathol Exp Neurol. 1995;54:304-310.
    • (1995) J Neuropathol Exp Neurol. , vol.54 , pp. 304-310
    • Wesseling, P.1    Schlingemann, R.O.2    Rietveld, F.J.3    Link, M.4    Burger, P.C.5    Ruiter, D.J.6
  • 38
    • 84901443568 scopus 로고    scopus 로고
    • Neutralizing endosialin antibody, morab-004, enhances efficacy of taxotere in a metastatic melanoma model
    • Krauthauser C, Grasso L, Nicolaides NC, Lin JM. Neutralizing Endosialin antibody, MORAb-004, enhances efficacy of TAXOTERE in a metastatic melanoma model. Cancer Res. 2012;72(suppl 1):4410.
    • (2012) Cancer Res. , vol.72 , Issue.SUPPL. 1 , pp. 4410
    • Krauthauser, C.1    Grasso, L.2    Nicolaides, N.C.3    Lin, J.M.4


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