Serial comprehensive geriatric assessment in elderly head and neck cancer patients undergoing curative radiotherapy identifies evolution of multidimensional health problems and is indicative of quality of life

European Journal of Cancer Care

Volumn 23, Issue 3, 2014, Pages 401-412

  Pottel, L ^a   Lycke, M ^a   Boterberg, T ^b   Pottel, H ^c   Goethals, L ^a   Duprez, F ^b   Van Den Noortgate, N ^b   De Neve, W ^b   Rottey, S ^b   Geldhof, K ^d   Buyse, V ^e   Kargar Samani, K ^f   Ghekiere, V ^a   Debruyne, P R ^a,g  

^a General Hospital Groeninge   (Belgium)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d Jan Yperman Hospital   (Belgium)

^e Department of Medicine   (Belgium)

^f Department of Nephrology   (Belgium)

^g UNIVERSITY OF GREENWICH   (United Kingdom)

Author keywords

Comprehensive geriatric assessment; Curative treatment; Elderly; Head and neck cancer; Health related quality of life; Supportive care

Indexed keywords

AGED; CARCINOMA, SQUAMOUS CELL; CHEMORADIOTHERAPY; DAILY LIFE ACTIVITY; FEASIBILITY STUDY; FEMALE; GERIATRIC ASSESSMENT; HEAD AND NECK NEOPLASMS; HUMAN; MALE; MASS SCREENING; PROCEDURES; PROSPECTIVE STUDY; QUALITY OF LIFE; RADIOTHERAPY; VERY ELDERLY;

ACTIVITIES OF DAILY LIVING; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CHEMORADIOTHERAPY; FEASIBILITY STUDIES; FEMALE; GERIATRIC ASSESSMENT; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MASS SCREENING; PROSPECTIVE STUDIES; QUALITY OF LIFE; RADIOTHERAPY;

EID: 84899470856     PISSN: 09615423     EISSN: 13652354     Source Type: Journal    
DOI: 10.1111/ecc.12179     Document Type: Article

References (52)

1. Aapro M.S., Kohne C.H., Cohen H.J. & Extermann M. (2005) Never too old? Age should not be a barrier to enrollment in cancer clinical trials. The Oncologist 10, 198-204.
2. Aaronson N.K., Ahmedzai S., Bergman B, Bullinger M., Cull A., Duez N.J., Filiberti A., Flechtner H., Fleishman S.B. & De Haes J.C. (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute 85, 365-376.
3. Bellera C.A., Rainfray M., Mathoulin-Pelissier S., Mertens C., Delva F., Fonck M. & Soubeyran P.L. (2012) Screening older cancer patients: first evaluation of the G-8 geriatric screening tool. Annals of Oncology 23, 2166-2172.
4. Bjordal K., Hammerlid E., Ahlner-Elmqvist M., De Graeff A., Boysen M., Evensen J.F., Biorklund A., De Leeuw J.R., Fayers P.M., Jannert M., Westin T. & Kaasa S. (1999) Quality of life in head and neck cancer patients: validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-H&N35. Journal of Clinical Oncology 17, 1008-1019.
5. Black R., Greenberg B., Ryan J.M., Posner H., Seeburger J., Amatniek J., Resnick M., Mohs R., Miller D.S., Saumier D., Carrillo M.C. & Stern Y. (2009) Scales as outcome measures for Alzheimer's disease. Alzheimer's and Dementia 5, 324-339.
6. Bond S.M., Dietrich M.S. & Murphy B.A. (2012) Neurocognitive function in head and neck cancer patients prior to treatment. Supportive Care in Cancer 20, 149-157.
7. Bottomley A. (2002) The cancer patient and quality of life. The Oncologist 7, 120-125.
8. Brown B.B., 1968. Delphi Process: A Methodology Used for the Elicitation of Opinions of Experts. An earlier paper published by RAND (Document No: P-3925).
9. Chen A.M., Jennelle R.L., Grady V., Tovar A., Bowen K., Simonin P., Tracy J., Mccrudden D., Stella J.R. & Vijayakumar S. (2009) Prospective study of psychosocial distress among patients undergoing radiotherapy for head and neck cancer. International Journal of Radiation Oncology, Biology, Physics 73, 187-193.
10. Datema F.R., Ferrier M.B., Van Der Schroeff M.P. & Baatenburg De Jong R.J. (2010) Impact of comorbidity on short-term mortality and overall survival of head and neck cancer patients. Head and Neck 32, 728-736.
11. Debruyne P.R., Knott V.E. & Pattison N.A. (2013) A call for rigorous research and transparent study reporting. European Journal of Cancer Care 22, 421-422.
12. Droz J.P., Balducci L., Bolla M., Emberton M., Fitzpatrick J.M., Joniau S., Kattan M.W., Monfardini S., Moul J.W., Naeim A., Van Poppel H., Saad F. & Sternberg C.N. (2010) Management of prostate cancer in older men: recommendations of a working group of the International Society of Geriatric Oncology. BJU International 106, 462-469.
13. Extermann M. (2000) Measuring comorbidity in older cancer patients. European Journal of Cancer 36, 453-471.
14. Extermann M. & Hurria A. (2007) Comprehensive geriatric assessment for older patients with cancer. Journal of Clinical Oncology 25, 1824-1831.
15. Extermann M., Meyer J., Mcginnis M., Crocker T.T., Corcoran M.B., Yoder J., Haley W.E., Chen H., Boulware D. & Balducci L. (2004) A comprehensive geriatric intervention detects multiple problems in older breast cancer patients. Critical Reviews in Oncology 49, 69-75.
16. Extermann M., Aapro M., Bernabei R., Cohen H.J., Droz J.P., Lichtman S., Mor V., Monfardini S., Repetto L., Sorbye L. & Topinkova E. (2005) Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Critical Reviews in Oncology 55, 241-252.
17. Forastiere A.A., Goepfert H., Maor M., Pajak T.F., Weber R., Morrison W., Glisson B., Trotti A., Ridge J.A., Chao C., Peters G., Lee D.J., Leaf A., Ensley J. & Cooper J. (2003) Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. The New England Journal of Medicine 349, 2091-2098.
18. Gan H.K., Bernstein L.J., Brown J., Ringash J., Vakilha M., Wang L., Goldstein D., Kim J., Hope A., O'sullivan B., Waldron J., Abdul Razak A.R., Chen E.X. & Siu L.L. (2011) Cognitive functioning after radiotherapy or chemoradiotherapy for head-and-neck cancer. International Journal of Radiation Oncology, Biology, Physics 81, 126-134.
19. Givens D.J., Karnell L.H., Gupta A.K., Clamon G.H., Pagedar N.A., Chang K.E., Van Daele D.J. & Funk G.F. (2009) Adverse events associated with concurrent chemoradiation therapy in patients with head and neck cancer. Archives of Otolaryngology - Head and Neck Surgery 135, 1209-1217.
20. Gomez-Millan J. (2009) Radiation therapy in the elderly: more side effects and complications? Critical Reviews in Oncology 71, 70-78.
21. Hamaker M.E., Jonker J.M., De Rooij S.E., Vos A.G., Smorenburg C.H. & Van Munster B.C. (2012) Frailty screening methods for predicting outcome of a comprehensive geriatric assessment in elderly patients with cancer: a systematic review. The Lancet Oncology 13, e437-e444.
22. Horiot J.C. (2007) Radiation therapy and the geriatric oncology patient. Journal of Clinical Oncology 25, 1930-1935.
23. Hurria A., Togawa K., Mohile S.G., Owusu C., Klepin H.D., Gross C.P., Lichtman S.M., Gajra A., Bhatia S., Katheria V., Klapper S., Hansen K., Ramani R., Lachs M., Wong F.L. & Tew W.P. (2011) Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. Journal of Clinical Oncology 29, 3457-3465.
24. Hutchins L.F., Unger J.M., Crowley J.J., Coltman C.A. Jr & Albain K.S. (1999) Underrepresentation of patients 65 years of age or older in cancer-treatment trials. The New England Journal of Medicine 341, 2061-2067.
25. Iconomou G., Mega V., Koutras A., Iconomou A.V. & Kalofonos H.P. (2004) Prospective assessment of emotional distress, cognitive function, and quality of life in patients with cancer treated with chemotherapy. Cancer 101, 404-411.
26. Kellen E., Bulens P., Deckx L., Schouten H., Van Dijk M., Verdonck I. & Buntinx F. (2010) Identifying an accurate pre-screening tool in geriatric oncology. Critical Reviews in Oncology 75, 243-248.
27. Ketelaars L., Pottel L., Lycke M., Goethals L., Ghekiere V., Santy L., Boterberg T., Van Den Noortgate N., Pottel H. & Debruyne P.R. (2013) Use of the Freund clock drawing test within the mini-cog as a screening tool for cognitive impairment in elderly patients with or without cancer. Journal of Geriatric Oncology 4, 174-182.
28. Lees J. (1999) Incidence of weight loss in head and neck cancer patients on commencing radiotherapy treatment at a regional oncology centre. European Journal of Cancer Care 8, 133-136.
29. Massie M.J. (2004) Prevalence of depression in patients with cancer. Journal of the National Cancer Institute. Monographs 32, 57-71.
30. Mehanna H., West C.M., Nutting C. & Paleri V. (2010) Head and neck cancer - Part 2: treatment and prognostic factors. BMJ (Clinical Research Ed.) 341, c4690.
31. Miller M. & Tower A. (1991) A Manual of Guidelines for Scoring the Cumulative Illness Rating Scale for Geriatrics (CIRS-G). University of Pittsburgh, Pittsburgh, PA, USA.
32. Mitchell A.J. (2009) A meta-analysis of the accuracy of the mini-mental state examination in the detection of dementia and mild cognitive impairment. Journal of Psychiatric Research 43, 411-431.
33. Mohile S.G., Bylow K., Dale W., Dignam J., Martin K., Petrylak D.P., Stadler W.M. & Rodin M. (2007) A pilot study of the vulnerable elders survey-13 compared with the comprehensive geriatric assessment for identifying disability in older patients with prostate cancer who receive androgen ablation. Cancer 109, 802-810.
34. NCCN 2013. NCCN Guidelines for Senior Adult Oncology, version 1.2014. Available at: http://www.nccn.org/professionals/physician_gls/pdf/senior.pdf
35. Nguyen N.P., Sallah S., Karlsson U. & Antoine J.E. (2002) Combined chemotherapy and radiation therapy for head and neck malignancies: quality of life issues. Cancer 94, 1131-1141.
36. O'keeffe S.T., Mulkerrin E.C., Nayeem K., Varughese M. & Pillay I. (2005) Use of serial Mini-Mental State Examinations to diagnose and monitor delirium in elderly hospital patients. Journal of the American Geriatrics Society 53, 867-870.
37. Overgaard J. (2009) Chemoradiotherapy of head and neck cancer-can the bumble bee fly? Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology 92, 1-3.
38. Pallis A.G., Fortpied C., Wedding U., Van Nes M.C., Penninckx B., Ring A., Lacombe D., Monfardini S., Scalliet P. & Wildiers H. (2010) EORTC elderly task force position paper: approach to the older cancer patient. European Journal of Cancer 46, 1502-1513.
39. Paula J.M., Sonobe H.M., Nicolussi A.C., Zago M.M. & Sawada N.O. (2012) Symptoms of depression in patients with cancer of the head and neck undergoing radiotherapy treatment: a prospective study. Revista Latino-Americana de Enfermagem 20, 362-368.
40. Pottel L., Boterberg T., Pottel H., Goethals L., Van Den Noortgate N., Duprez F., De Neve W., Rottey S., Geldhof K., Van Eygen K., Kargar-Samani K., Ghékiere V., Cornelis F., Mohile S.G. & Debruyne P.R. (2012a) Determination of an adequate screening tool for identification of vulnerable elderly head and neck cancer patients treated with radio(chemo)therapy. Journal of Geriatric Oncology 3, 24-32.
41. Pottel L., Lycke M., Boterberg T., Ketelaars L., Pottel H., Goethals L., Van Den Noortgate N., Duprez F., De Neve W., Rottey S., Geldhof K., Van Eygen K., Kargar-Samani K., Ghekiere V., Verhaeghe A. & Debruyne P.R. (2012b) Experience with Lexicomp® online drug database for medication review and drug-drug interaction analysis within a comprehensive geriatric assessment in elderly cancer patients. Journal of Analytical Oncology 1, 32-41.
42. Pottel L., Lycke M., Boterberg T., Foubert I., Pottel H., Duprez F., Goethals L. & Debruyne P.R. (2013) Omega-3 fatty acids: physiology, biological sources and potential applications in supportive cancer care. Phytochemistry Reviews. doi: 10.1007/s11101-013-9309-1
43. Rodin M.B. & Mohile S.G. (2007) A practical approach to geriatric assessment in oncology. Journal of Clinical Oncology 25, 1936-1944.
44. Saliba D., Elliott M., Rubenstein L.Z., Solomon D.H., Young R.T., Kamberg C.J., Roth C., Maclean C.H., Shekelle P.G., Sloss E.M. & Wenger N.S. (2001) The Vulnerable Elders Survey: a tool for identifying vulnerable older people in the community. Journal of the American Geriatrics Society 49, 1691-1699.
45. Silver H.J., De Campos Graf Guimaraes C., Pedruzzi P., Badia M., Spuldaro De Carvalho A., Oliveira B.V., Ramos G.H., Dietrich M.S. & Pietrobon R. (2010) Predictors of functional decline in locally advanced head and neck cancer patients from south Brazil. Head and Neck 32, 1217-1225.
46. Spoletini I., Gianni W., Repetto L., Bria P., Caltagirone C., Bossu P. & Spalletta G. (2008) Depression and cancer: an unexplored and unresolved emergent issue in elderly patients. Critical Reviews in Oncology 65, 143-155.
47. Stuck A.E., Siu A.L., Wieland G.D., Adams J. & Rubenstein L.Z. (1993) Comprehensive geriatric assessment: a meta-analysis of controlled trials. Lancet 342, 1032-1036.
48. Stuck A.E., Walthert J.M., Nikolaus T., Bula C.J., Hohmann C. & Beck J.C. (1999) Risk factors for functional status decline in community-living elderly people: a systematic literature review. Social Science and Medicine 48, 445-469.
49. Terret C., Albrand G. & Droz J.P. (2004) Geriatric assessment in elderly patients with prostate cancer. Clinical Prostate Cancer 2, 236-240.
50. Vanderwalde N.A., Fleming M., Weiss J. & Chera B.S. (2013) Treatment of older patients with head and neck cancer: a review. The Oncologist 18, 568-578.
51. Vandewoude M. (2010) Nutritional assessment in geriatric cancer patients. Supportive Care in Cancer 18 (Suppl. 2), S51-S56.
52. Wilson R.S., Schneider J.A., Boyle P.A., Arnold S.E., Tang Y. & Bennett D.A. (2007) Chronic distress and incidence of mild cognitive impairment. Neurology 68, 2085-2092.