The application of a new microfluidic device for the simultaneous identification and quantitation of midazolam metabolites obtained from a single micro-litre of chimeric mice blood

Rapid Communications in Mass Spectrometry

Volumn 28, Issue 11, 2014, Pages 1293-1302

  Gallagher, Richard ^a   Dillon, Leonard ^c   Grimsley, Aidan ^a   Murphy, Jim ^c   Samuelsson, Kristin ^b   Douce, David ^c  

^a ASTRAZENECA   (United Kingdom)

^b ASTRAZENECA R AND D   (Sweden)

^c WATERS CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; BLOOD; COLUMN CHROMATOGRAPHY; FLUIDIC DEVICES; ION SOURCES; MAMMALS; MASS SPECTROMETERS; MICROFLUIDICS; PHARMACOKINETICS;

BLOOD SAMPLING; LOW FLOW; MICROFLUIDICS DEVICES; MIDAZOLAM; SAMPLE VOLUME; SAMPLING VOLUME; SIMULTANEOUS IDENTIFICATION; SMALL SAMPLES; ULTRA-HIGH; WHOLE BLOOD;

METABOLITES;

MIDAZOLAM;

ANIMAL; BLOOD; CHEMICAL STRUCTURE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; EVALUATION STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICROFLUIDIC ANALYSIS; MOUSE; PROCEDURES;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MICE; MICROFLUIDIC ANALYTICAL TECHNIQUES; MIDAZOLAM; MOLECULAR STRUCTURE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84899463375     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.6902     Document Type: Article

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