Levuglandin forms adducts with histone H4 in a cyclooxygenase-2-dependent manner, altering its interaction with DNA

Biochemistry

Volumn 53, Issue 15, 2014, Pages 2436-2441

  Carrier, Erica J ^b   Zagol Ikapitte, Irene ^b   Amarnath, Venkataraman ^b   Boutaud, Olivier ^a   Oates, John A ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS;

CULTURED CELL; CYCLOOXYGENASE 2; HISTONE H4; INTERACTION WITH DNAS; LIVER TISSUE; NUCLEOSOME STRUCTURE; NUCLEOSOMES; PRIMARY AMINES;

PATHOLOGY;

ALDEHYDE; CYCLOOXYGENASE 2; DNA; HISTONE H4; LEVUGLANDIN; LYSINE; PROSTAGLANDIN; PROSTAGLANDIN E2; SCAVENGER; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CELL LINE; CONTROLLED STUDY; DNA ADDUCT; DNA HISTONE INTERACTION; HUMAN; HUMAN CELL; INTERACTIONS WITH DNA; LIQUID CHROMATOGRAPHY; LIVER; MASS SPECTROMETRY; NUCLEOSOME; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS;

CHROMATOGRAPHY, LIQUID; CYCLOOXYGENASE 2; DNA; HISTONES; MASS SPECTROMETRY; PROSTAGLANDIN D2; PROSTAGLANDINS E; SOLUBILITY;

EID: 84899446092     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi401673b     Document Type: Article

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