NrCAM-regulating neural systems and addiction-related behaviors

Addiction Biology

Volumn 19, Issue 3, 2014, Pages 343-353

  Ishiguro, Hiroki ^a,b   Hall, Frank S ^c   Horiuchi, Yasue ^b   Sakurai, Takeshi ^d   Hishimoto, Akitoyo ^e   Grumet, Martin ^f   Uhl, George R ^c   Onaivi, Emmanuel S ^g   Arinami, Tadao ^b  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e KOBE UNIVERSITY   (Japan)

^f RUTGERS UNIVERSITY   (United States)

^g WILLIAM PATERSON UNIVERSITY   (United States)

Author keywords

Behavior; cell adhesion molecule; glutamate

Indexed keywords

GLUTAMIC ACID; GLUTAMINASE; MORPHINE; NERVE CELL ADHESION MOLECULE; PROLINE DERIVATIVE; TRANSCRIPTOME; ALCOHOL; CELL ADHESION MOLECULE; CENTRAL DEPRESSANT AGENT; MELANOSTATIN; NARCOTIC ANALGESIC AGENT; NRCAM PROTEIN, MOUSE;

ADDICTION; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BEHAVIOR; COMPULSION; CONTROLLED STUDY; DRUG RESPONSE; GENOTYPE; HABITUATION; HETEROZYGOTE; HOMEOSTASIS; HOT PLATE TEST; LOCOMOTION; MALE; MOUSE; NONHUMAN; PAIN THRESHOLD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBSTANCE ABUSE; TAIL FLICK TEST; ADAPTIVE BEHAVIOR; ANIMAL; C57BL MOUSE; CONDITIONING; DRINKING BEHAVIOR; DRUG EFFECTS; EXPLORATORY BEHAVIOR; KNOCKOUT MOUSE; MAZE TEST; PATHOPHYSIOLOGY; PHYSIOLOGY; REACTION TIME; SOCIAL BEHAVIOR;

ADAPTATION, PSYCHOLOGICAL; ALCOHOL DRINKING; ANALGESICS, OPIOID; ANIMALS; ANXIETY; BEHAVIOR, ADDICTIVE; CELL ADHESION MOLECULES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CONDITIONING (PSYCHOLOGY); ETHANOL; EXPLORATORY BEHAVIOR; MALE; MAZE LEARNING; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHINE; MSH RELEASE-INHIBITING HORMONE; REACTION TIME; SOCIAL BEHAVIOR;

EID: 84899417103     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/j.1369-1600.2012.00469.x     Document Type: Article

References (57)

1. Ballaz SJ, Akil H, Watson SJ, (2007) The 5-HT7 receptor: role in novel object discrimination and relation to novelty-seeking behavior. Neuroscience 149: 192-202.
2. Bienkowski P, Koros E, Kostowski W, (2001) Novelty-seeking behaviour and operant oral ethanol self-administration in Wistar rats. Alcohol Alcohol 36: 525-528.
3. Bruins Slot LA, Bardin L, Auclair AL, Depoortere R, Newman-Tancredi A, (2008) Effects of antipsychotics and reference monoaminergic ligands on marble burying behavior in mice. Behav Pharmacol 19: 145-152.
4. Cloninger CR, Svrakic DM, Przybeck TR, (1993) A psychobiological model of temperament and character. Arch Gen Psychiatry 50: 975-990.
5. Conway KP, Kane RJ, Ball SA, Poling JC, Rounsaville BJ, (2003) Personality, substance of choice, and polysubstance involvement among substance dependent patients. Drug Alcohol Depend 71: 65-75.
6. Custer AW, Kazarinova-Noyes K, Sakurai T, Xu X, Simon W, Grumet M, Shrager P, (2003) The role of the ankyrin-binding protein NrCAM in node of Ranvier formation. J Neurosci 23: 10032-10039.
7. Deacon RM, Rawlins JN, (2005) Hippocampal lesions, species-typical behaviours and anxiety in mice. Behav Brain Res 156: 241-249.
8. Ducci F, Enoch MA, Funt S, Virkkunen M, Albaugh B, Goldman D, (2007) Increased anxiety and other similarities in temperament of alcoholics with and without antisocial personality disorder across three diverse populations. Alcohol 41: 3-12.
9. Egashira N, Okuno R, Harada S, Matsushita M, Mishima K, Iwasaki K, Nishimura R, Oishi R, Fujiwara M, (2008) Effects of glutamate-related drugs on marble-burying behavior in mice: implications for obsessive-compulsive disorder. Eur J Pharmacol 586: 164-170.
10. Ennaceur A, Delacour J, (1988) A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data. Behav Brain Res 31: 47-59.
11. Evren C, Evren B, Yancar C, Erkiran M, (2007) Temperament and character model of personality profile of alcohol- and drug-dependent inpatients. Compr Psychiatry 48: 283-288.
12. Finn PR, Mazas CA, Justus AN, Steinmetz J, (2002) Early-onset alcoholism with conduct disorder: Go/No Go learning deficits, working memory capacity, and personality. Alcohol Clin Exp Res 26: 186-206.
13. Friedman I, Dar R, Shilony E, (2000) Compulsivity and obsessionality in opioid addiction. J Nerv Ment Dis 188: 155-162.
14. Gass JT, Olive MF, (2008) Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol 75: 218-265.
15. Gerra G, Bertacca S, Zaimovic A, Pirani M, Branchi B, Ferri M, (2008) Relationship of personality traits and drug of choice by cocaine addicts and heroin addicts. Subst Use Misuse 43: 317-330.
16. Gerra G, Zaimovic A, Timpano M, Zambelli U, Begarani M, Marzocchi GF, Ferri M, Delsignore R, Brambilla F, (2000) Neuroendocrine correlates of temperament traits in abstinent opiate addicts. J Subst Abuse 11: 337-354.
17. Grueter BA, Rothwell PE, Malenka RC, (2011) Integrating synaptic plasticity and striatal circuit function in addiction. Curr Opin Neurobiol http://dx.doi.org/10.1016/j.conb.2011.09.009. [Epub ahead of print].
18. Hall FS, Li XF, Goeb M, Roff S, Hoggatt H, Sora I, Uhl GR, (2003) Congenic C57BL/6 mu opiate receptor (MOR) knockout mice: baseline and opiate effects. Genes Brain Behav 2: 114-121.
19. Hollander E, Kim S, Khanna S, Pallanti S, (2007) Obsessive-compulsive disorder and obsessive-compulsive spectrum disorders: diagnostic and dimensional issues. CNS Spectr 12: 5-13.
20. Hosak L, Preiss M, Halir M, Cermakova E, Csemy L, (2004) Temperament and character inventory (TCI) personality profile in metamphetamine abusers: a controlled study. Eur Psychiatry 19: 193-195.
21. Ichimaru Y, Egawa T, Sawa A, (1995) 5-HT1A-receptor subtype mediates the effect of fluvoxamine, a selective serotonin reuptake inhibitor, on marble-burying behavior in mice. Jpn J Pharmacol 68: 65-70.
22. Ishiguro H, Liu QR, Gong JP, Hall FS, Ujike H, Morales M, Sakurai T, Grumet M, Uhl GR, (2006) NrCAM in addiction vulnerability: positional cloning, drug-regulation, haplotype-specific expression, and altered drug reward in knockout mice. Neuropsychopharmacology 31: 572-584.
23. Joel D, (2006) Current animal models of obsessive compulsive disorder: a critical review. Prog Neuropsychopharmacol Biol Psychiatry 30: 374-388.
24. Kalivas PW, Lalumiere RT, Knackstedt L, Shen H, (2009) Glutamate transmission in addiction. Neuropharmacology 56 (Suppl 1): 169-173.
25. Kim HJ, Kim HG, Kim MH, Kwack KB, Park JK, Kim T, Kim JW, Ban JY, Chung JH, (2009) Association between neuronal cell adhesion molecule (NRCAM) single nucleotide polymorphisms and schizophrenia in a Korean population. Psychiatry Clin Neurosci 63: 123-124.
26. Kirby LG, Zeeb FD, Winstanley CA, (2011) Contributions of serotonin in addiction vulnerability. Neuropharmacology 61: 421-432.
27. Knackstedt LA, Moussawi K, Lalumiere R, Schwendt M, Klugmann M, Kalivas PW, (2010) Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking. J Neurosci 30: 7984-7992.
28. Koyuncuoglu H, Aricioglu F, Uresin Y, Dizdar Y, Esin Y, (1992) Effects of tizanidine on morphine physical dependence: attenuation and intensification. Pharmacol Biochem Behav 42: 693-698.
29. Lukasiewicz M, Neveu X, Blecha L, Falissard B, Reynaud M, Gasquet I, (2008) Pathways to substance-related disorder: a structural model approach exploring the influence of temperament, character, and childhood adversity in a national cohort of prisoners. Alcohol Alcohol 43: 287-295.
30. Lustig M, Erskine L, Mason CA, Grumet M, Sakurai T, (2001) Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. J Comp Neurol 434: 13-28.
31. Lustig M, Sakurai T, Grumet M, (1999) Nr-CAM promotes neurite outgrowth from peripheral ganglia by a mechanism involving axonin-1 as a neuronal receptor. Dev Biol 209: 340-351.
32. Lynskey MT, Fergusson DM, Horwood LJ, (1998) The origins of the correlations between tobacco, alcohol, and cannabis use during adolescence. J Child Psychol Psychiatry 39: 995-1005.
33. Mancebo MC, Grant JE, Pinto A, Eisen JL, Rasmussen SA, (2009) Substance use disorders in an obsessive compulsive disorder clinical sample. J Anxiety Disord 23: 429-435.
34. Martinotti G, Cloninger CR, Janiri L, (2008) Temperament and character inventory dimensions and anhedonia in detoxified substance-dependent subjects. Am J Drug Alcohol Abuse 34: 177-183.
35. Marui T, Funatogawa I, Koishi S, Yamamoto K, Matsumoto H, Hashimoto O, Nanba E, Nishida H, Sugiyama T, Kasai K, Watanabe K, Kano Y, Sasaki T, Kato N, (2009) Association of the neuronal cell adhesion molecule (NRCAM) gene variants with autism. Int J Neuropsychopharmacol 12: 1-10.
36. Matzel LD, Babiarz J, Townsend DA, Grossman HC, Grumet M, (2008) Neuronal cell adhesion molecule deletion induces a cognitive and behavioral phenotype reflective of impulsivity. Genes Brain Behav 7: 470-480.
37. Moy SS, Nadler JJ, Perez A, Barbaro RP, Johns JM, Magnuson TR, Piven J, Crawley JN, (2004) Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice. Genes Brain Behav 3: 287-302.
38. Moy SS, Nonneman RJ, Young NB, Demyanenko GP, Maness PF, (2009) Impaired sociability and cognitive function in Nrcam-null mice. Behav Brain Res 205: 123-131.
39. Nicolas LB, Kolb Y, Prinssen EP, (2006) A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants. Eur J Pharmacol 547: 106-115.
40. Njung'e K, Handley SL, (1991) Evaluation of marble-burying behavior as a model of anxiety. Pharmacol Biochem Behav 38: 63-67.
41. Olive MF, (2009) Metabotropic glutamate receptor ligands as potential therapeutics for addiction. Curr Drug Abuse Rev 2: 83-989.
42. Petralia RS, Sans N, Wang YX, Wenthold RJ, (2005) Ontogeny of postsynaptic density proteins at glutamatergic synapses. Mol Cell Neurosci 29: 436-452.
43. Saadat KS, Elliott JM, Colado MI, Green AR, (2006) The acute and long-term neurotoxic effects of MDMA on marble burying behaviour in mice. J Psychopharmacol 20: 264-271.
44. Sakurai T, Lustig M, Babiarz J, Furley AJ, Tait S, Brophy PJ, Brown SA, Brown LY, Mason CA, Grumet M, (2001) Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development. J Cell Biol 154: 1259-1273.
45. Sakurai T, Lustig M, Nativ M, Hemperly JJ, Schlessinger J, Peles E, Grumet M, (1997) Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase beta. J Cell Biol 136: 907-918.
46. Sher KJ, Bartholow BD, Wood MD, (2000) Personality and substance use disorders: a prospective study. J Consult Clin Psychol 68: 818-829.
47. Sora I, Elmer G, Funada M, Pieper J, Li XF, Hall FS, Uhl GR, (2001a) Mu opiate receptor gene dose effects on different morphine actions: evidence for differential in vivo mu receptor reserve. Neuropsychopharmacology 25: 41-54.
48. Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, Wichems C, Lesch KP, Murphy DL, Uhl GR, (2001b) Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci U S A 98: 5300-5305.
49. Sora I, Takahashi N, Funada M, Ujike H, Revay RS, Donovan DM, Miner LL, Uhl GR, (1997) Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia. Proc Natl Acad Sci U S A 94: 1544-1549.
50. Sora I, Wichems C, Takahashi N, Li XF, Zeng Z, Revay R, Lesch KP, Murphy DL, Uhl GR, (1998) Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc Natl Acad Sci U S A 95: 7699-7704.
51. Takahashi N, Miner LL, Sora I, Ujike H, Revay RS, Kostic V, Jackson-Lewis V, Przedborski S, Uhl GR, (1997) VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity. Proc Natl Acad Sci U S A 94: 9938-9943.
52. Thomas A, Burant A, Bui N, Graham D, Yuva-Paylor LA, Paylor R, (2009) Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety. Psychopharmacology (Berl) 204: 361-373.
53. Tzschentke TM, Schmidt WJ, (2003) Glutamatergic mechanisms in addiction. Mol Psychiatry 8: 373-382.
54. Umathe S, Bhutada P, Dixit P, Shende V, (2008) Increased marble-burying behavior in ethanol-withdrawal state: modulation by gonadotropin-releasing hormone agonist. Eur J Pharmacol 587: 175-180.
55. Umathe SN, Vaghasiya JM, Jain NS, Dixit PV, (2009) Neurosteroids modulate compulsive and persistent behavior in rodents: implications for obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry 33: 1161-1166.
56. Uys JD, LaLumiere RT, (2008) Glutamate: the new frontier in pharmacotherapy for cocaine addiction. CNS Neurol Disord Drug Targets 7: 482-491.
57. Wills TA, Vaccaro D, McNamara G, (1994) Novelty seeking, risk taking, and related constructs as predictors of adolescent substance use: an application of Cloninger's theory. J Subst Abuse 6: 1-20. Technology Technology