T-helper 2 cytokines, transforming growth factor β1, and eosinophil products induce fibrogenesis and alter muscle motility in patients with eosinophilic esophagitis

Gastroenterology

Volumn 146, Issue 5, 2014, Pages

  Rieder, Florian ^a,b   Nonevski, Ilche ^a   Ma, Jie ^c   Ouyang, Zhufeng ^a   West, Gail ^b   Protheroe, Cheryl ^d   Depetris, Giovanni ^e   Schirbel, Anja ^b   Lapinski, James ^b   Goldblum, John ^b   Bonfield, Tracey ^f   Lopez, Rocio ^b   Harnett, Karen ^c   Lee, James ^d   Hirano, Ikuo ^g   Falk, Gary ^a   Biancani, Piero ^c   Fiocchi, Claudio ^a,b  

^a Digestive Disease Institute   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c RHODE ISLAND HOSPITAL   (United States)

^d MAYO GRADUATE SCHOOL   (United States)

^e MAYO CLINIC   (United States)

^f CASE WESTERN RESERVE UNIVERSITY   (United States)

^g NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Immune Regulation; Keywords; Primary Human Cells; Swallowing; Transmural Disease

Indexed keywords

ACETYLCHOLINE; COLLAGEN TYPE 1; CYTOKINE; FIBRONECTIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; ARTICLE; CELL INTERACTION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; COCULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INHIBITION; EOSINOPHIL; EOSINOPHILIC ESOPHAGITIS; ESOPHAGOSCOPY; ESOPHAGUS BIOPSY; ESOPHAGUS MUSCLE; ESOPHAGUS RESECTION; FEMALE; FIBROGENESIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN ESOPHAGEAL FIBROBLAST; HUMAN ESOPHAGEAL MUSCLE CELL; HUMAN TISSUE; LEUKOCYTE ADHERENCE; MALE; MESENCHYME CELL; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE EXCITATION; MYOFIBROBLAST; PRIMARY CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TH2 CELL;

IMMUNE REGULATION; PRIMARY HUMAN CELLS; SWALLOWING; TRANSMURAL DISEASE;

EOSINOPHILIC ESOPHAGITIS; AGED; BIOPSY; CASE-CONTROL STUDIES; CELL ADHESION; CELL COMMUNICATION; CELLS, CULTURED; COCULTURE TECHNIQUES; COLLAGEN TYPE I; CYTOKINES; DEGLUTITION; DEGLUTITION DISORDERS; EOSINOPHILS; ESOPHAGOSCOPY; FEMALE; FIBROBLASTS; FIBRONECTINS; FIBROSIS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; MUCOUS MEMBRANE; MUSCLE CONTRACTION; MYOCYTES, SMOOTH MUSCLE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TH2 CELLS; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84899413672     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.01.051     Document Type: Article

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