Inhibition of NADPH oxidase prevents acute lung injury in obese rats following severe trauma

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 306, Issue 5, 2014, Pages

  Xiang, Lusha ^a   Lu, Silu ^a   Mittwede, Peter N ^a   Clemmer, John S ^a   Hester, Robert L ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

And vascular permeability; Lung injury; Obesity; Reactive oxygen species; Trauma

Indexed keywords

APOCYNIN; INTERLEUKIN 6; MYELOPEROXIDASE; PHENAZINE METHOSULFATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ACETOPHENONE DERIVATIVE; AUTACOID; ENZYME INHIBITOR; NITRIC OXIDE; PEROXIDASE; REACTIVE OXYGEN METABOLITE;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PARAMETERS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FIBULA FRACTURE; HINDLIMB; INFLAMMATION; INJURY SEVERITY; LUNG BLOOD VESSEL; LUNG CAPILLARY FILTRATION COEFFICIENT; LUNG EDEMA; LUNG VASCULAR RESISTANCE; LUNG WEIGHT; MALE; MUSCLE INJURY; NEUTROPHIL COUNT; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; AND VASCULAR PERMEABILITY; ANIMAL; BLOOD; CAPILLARY PERMEABILITY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; INJURY; LUNG; LUNG INJURY; METABOLISM; MULTIPLE TRAUMA; NEUTROPHIL CHEMOTAXIS; VASCULAR RESISTANCE; VASCULARIZATION; ZUCKER RAT;

AND VASCULAR PERMEABILITY; LUNG INJURY; OBESITY; REACTIVE OXYGEN SPECIES; TRAUMA;

ACETOPHENONES; ACUTE LUNG INJURY; ANIMALS; CAPILLARY PERMEABILITY; ENZYME INHIBITORS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LUNG; MALE; MULTIPLE TRAUMA; NADPH OXIDASE; NEUTROPHIL INFILTRATION; NITRIC OXIDE; OBESITY; OXIDATIVE STRESS; PEROXIDASE; PULMONARY EDEMA; RATS; RATS, ZUCKER; VASCULAR RESISTANCE;

EID: 84899412993     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00868.2013     Document Type: Article

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