Expressions of local renin-angiotensin system components in chondrocytes

European Journal of Histochemistry

Volumn 58, Issue 2, 2014, Pages 132-138

  Tsukamoto, I ^a   Akagi, M ^a   Inoue, S ^a   Yamagishi, K ^a   Mori, S ^a   Asada, S ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

Hyaline chondrocytes; Hypertrophic chondrocytes; Hypertrophy; Local RAS

Indexed keywords

EID: 84899154339     PISSN: 1121760X     EISSN: None     Source Type: Journal    
DOI: 10.4081/ejh.2014.2387     Document Type: Article

References (17)

1. Tigerstedt R, Bergman PG. Niere und Kreislauf. Skand Arch Physiol 1898;8:223-71.
2. Marks LS, Maxwell MH. Tigerstedt and the discovery of renin. An historical note. Hypertension 1979;1:384-8.
3. Paul M, Poyan Mehr A, Kreutz R. Physiology of local renin-angiotensin systems. Physiol Rev 2006;86:747-803.
4. Paul M, Bader M, Steckelings UM, Voigtländer T, Ganten D. The reninangiotensin system in the brain. Localization and functional significance. Arzneimittelforschung 1993;43:207-13.
5. Zhao W, Leung PY, Chew SB, Chan HC, Wong PY. Localization and distribution of angiotensin II in the rat epididymis J. Endocrinol 1996;149:217-22.
6. Price A, Lockhart JC, Ferrell WR, Gsell W, McLean S, Sturrock RD. Angiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis: in vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitis. Arthritis Rheum 2007;56:441-7.
7. Garcia P, Schwenzer S, Slotta JE, Scheuer C, Tami AE, Holstein JH, et al. Inhibition of angiotensin-converting enzyme stimulates fracture healing and periosteal callus formation-role of a local renin-angiotensin system. Br J Pharmacol 2010;159:1672-80.
8. Shimizu H, Nakagami H, Osako MK, Hanayama R, Kunugiza Y, Kizawa T, et al. Angiotensin II accelerates osteoporosis by activating osteoclasts. FASEB J 2008;22: 2465-75.
9. Rejnmark L, Vestergaard P, Mosekilde L. Treatment with beta-blockers. ACE inhibitors, and calcium-channel blockers is associated with a reduced fracture risk: a nationwide case-control study. J Hypertens 2006;24:581-9.
10. Tsukamoto I, Inoue S, Teramura T, Takehara T, Ohtani K, Akagi M. Activating types 1 and 2 angiotensin II receptors modulate the hypertrophic differentiation of chondrocytes FEBS Open Bio 2013;3:279-84.
11. Buckwalter JA, Mankin HJ. Articular cartilage, part I: Tissue design and chondrocytematrix interactions. J Bone Joint Surg 1997;79A:600-611.
12. Ulrich-Vinther M, Maloney MD, Schwarz EM, Rosier R, O'Keefe RJ. Articular cartilage biology. J Am Acad Orthop Surg 2003;11:421-30.
13. van der Eerden BC, Karperien M, Wit JM. Systemic and local regulation of the growth plate. Endocr Rev 2003;24:782-801.
14. Kronenberg HM. Developmental regulation of the growth plate. Nature 2003; 423:332-6.
15. Murata M, Yudoh K, Nakamura H, Kato T, Inoue K, Chiba J, et al. Distinct signaling pathways are involved in hypoxia-and IL-1-induced VEGF expression in human articular chondrocytes J Orthop Res 2006;24:1544-54.
16. Ohba T, Haro H, Ando T, Wako M, Suenaga F, Aso Y, et al. TNF-alpha-induced NF-kappaB signaling reverses age-related declines in VEGF induction and angiogenic activity in intervertebral disc tissues. J Orthop Res 2009;27:229-35.
17. Gerber HP, Vu TH, Ryan AM, Kowalski J, Werb Z, Ferrara N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 1999;5:623-8.