COX2 inhibition during nephrogenic period induces ANG II hypertension and sex-dependent changes in renal function during aging

American Journal of Physiology - Renal Physiology

Volumn 306, Issue 5, 2014, Pages

  Reverte, Virginia ^a   Tapia, Antonio ^a   Loria, Analia ^a   Salazar, Francisco ^a   Llinas, M Teresa ^a   Salazar, F Javier ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

COX2; Fetal programming; Hypertension; Renal function; Renal reserve; Sex and aging dependent changes

Indexed keywords

AMINO ACID; ANGIOTENSIN II; CANDESARTAN; CREATININE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; SODIUM;

AGING; AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; CREATININE CLEARANCE; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HEMODYNAMICS; HIGH SODIUM INTAKE; HYPERTENSION; KIDNEY FUNCTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; SEX; SODIUM LOAD; SYSTOLIC BLOOD PRESSURE; ULTRAFILTRATION; ANIMAL; COX2; DISEASE MODEL; DRUG EFFECT; FETAL PROGRAMMING; GLOMERULUS FILTRATION RATE; KIDNEY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; RENAL RESERVE; SEX- AND AGING-DEPENDENT CHANGES; SEXUAL DEVELOPMENT; SPRAGUE DAWLEY RAT;

COX2; FETAL PROGRAMMING; HYPERTENSION; RENAL FUNCTION; RENAL RESERVE; SEX- AND AGING-DEPENDENT CHANGES;

AGING; ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; CYCLOOXYGENASE 2 INHIBITORS; DISEASE MODELS, ANIMAL; FEMALE; GLOMERULAR FILTRATION RATE; HYPERTENSION; KIDNEY; MALE; PROTEINURIA; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS;

EID: 84899147371     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00535.2013     Document Type: Article

References (36)

1. Abbate M, Zoja C, Remuzzi G. How does proteinuria cause progressive renal damage? J Am Soc Nephrol 17: 2974-2984, 2006.
2. Alexander BT. Fetal programming of hypertension. Am J Physiol Regul Integr Comp Physiol 290: R1-R10, 2006.
3. Brenner BM. Nephron adaptation to renal injury or ablation. Am J Physiol Renal Fluid Electrolyte Physiol 249: F324-F337, 1985.
4. Ceravolo GS, Franco MC, Carneiro-Ramos MS, Barreto-Chaves ML, Tostes RC, Nigro D, Fortes ZB, Carvalho MH. Enalapril and losartan restored blood pressure and vascular reactivity in intrauterine undernourished rats. Life Sci 80: 782-787, 2007.
5. Diz Lewis K DI. Dahl Memorial Lecture. The renin-angiotensin system and aging. Hypertension 52: 37-43, 2008.
6. Gilbert JS, Nijland MJ. Sex-differences in the developmental origins of hypertension and cardiorenal disease. Am J Physiol Regul Integr Comp Physiol 295: R1941-R1952, 2008.
7. Gwathmey TM, Shaltout HA, Rose JC, Diz DI, Chappel MC. Glucocorticoid-induced fetal programming alters the functional complement of angiotensin receptor subtypes within the kidney. Hypertension 57: 620-626, 2011.
8. Hall JE. Control of sodium excretion by angiotensin II: intrarenal mechanisms and blood pressure regulation. Am J Physiol Regul Integr Comp Physiol 250: R960-R972, 1986.
9. Ji H, Wu X, Liu J, Ecelbarger CM, Watkins R, Arnold AP, Sandberg K. Sex chromosome effects unmasked in angiotensin II-induced hypertension. Hypertension 55: 1275-1282, 2010.
10. Langley-Evans SC, Jackson AA. Captopril normalizes systolic blood pressure in rats with hypertension induced by fetal exposure to maternal low-protein diets. Comp Biochem Physiol 110: 223-228, 1995.
11. Larsson L, Aperia A, Wilton P. Effect of normal development on compensatory renal growth. Kidney Int 18: 29-35, 1980.
12. Loria AS, Reverte V, Salazar F, Sáez F, Llinás MT, Salazar FJ. Changes in renal hemodynamics and excretory function induced by a reduction of ANG II effects during renal devlopment. Am J Physiol Regul Integr Comp Physiol 293: R695-R700, 2007.
13. Manning J, Vehaskari VM. Low birth weight-associated adult hypertension in the rat. Pediatr Nephrol 16: 417-422, 2001.
14. McMullen S, Gardner DS, Langley-Evans S. Prenatal programming of angiotensin type 2 receptor expression in the rat. Br J Nutr 91: 133-140, 2004.
15. Mizuno M, Lozano G, Baum M, Smith SA. Enalapril attenuates the exaggerated sympathetic response to physical stress in prenatally programmed hypertensive rats. Hypertension [Epub before print].
16. Navar LG, Inscho EW, Majid DSA, Imig JD, Harrison-Bernard LM, Mitchell KD. Paracrine regulation of the renal microcirculation. Physiol Rev 76: 425-536, 1996.
17. Nickenig G, Bäumer AT, Grohè C, Kahlert S, Strehlow K, Rosenkranz S, Stäblein A, Beckers F, Smits JF, Daemen MJ, Vetter H, Böhm M. Estrogen modulates AT1 receptor gene expression in vitro and in vivo. Circulation 97: 2197-2201, 1998.
18. Nilsson AB, Guron GS, Adams MA, Friberg P. Renal interstitial hydrostatic pressure and urinary sodium excretion in rats with angiotensinconverting enzyme inhibitor-induced papillary atrophy. Exp Physiol 84: 947-955, 1999.
19. Ojeda NB, Royals TP, Black JT, Dasinger JH, Johnson JM, Alexander BT. Enhanced sensitivity to acute angiotensin II is testosterone dependent in adult male growth-restricted offspring. Am J Physiol Regul Integr Comp Physiol 298: R1421-R1427, 2010.
20. Pinilla JM, Alberola A, González JD, Quesada T, Salazar FJ. Role of prostaglandins on the renal effects of angiotensin II and interstitial pressure during volume expansion. Am J Physiol Regul Integr Comp Physiol 265: R1469-R1474, 1993.
21. Prévot A, Mosig D, Martini S, Guignard JP. Nimesulide, a cyclooxygenase-2 preferential inhibitor, impairs renal function in the newborn rabbit. Pediatr Res 55: 254-260, 2004.
22. Reckelhoff JF. Gender differences in the regulation of blood pressure. Hypertension 37: 1199-1208, 2001.
23. Reverte V, Tapia A, Baile G, Gambini J, Gimenez I, Llinas MT, Salazar FJ. Role of angiotensin II on arterial pressure and renal hemodynamics in rats with an altered renal development. Age-and sexdependent differences. Am J Physiol Renal Physiol 304: F33-F40, 2013.
24. Reverte V, Tapia A, Moreno JM, Rodriguez L, Salazar F, Llinas MT, Salazar FJ. Renal effects of prolonged high protein intake and COX2 inhibition in hypertensive rats with an altered renal development. Am J Physiol Renal Physiol 301: F327-F333, 2011.
25. Saez F, Castells MT, Zuasti A, Salazar F, Reverte V, Loria A, Salazar FJ. Sex differences in the renal changes elicited by Ang II blockade during the nephrogenic period. Hypertension 49: 1429-1435, 2007.
26. Saez F, Reverte V, Salazar Castells MT, Llinas MT, Salazar FJ. Hypertension and sex differences in the age-related renal changes when cyclooxygenase-2 activity is reduced during nephrogenesis. Hypertension 53: 331-337, 2009.
27. Sahajpal V, Ashton N. Increased glomerular angiotensin II binding in rats exposed to a maternal low protein diet in utero. J Physiol 563: 193-201, 2005.
28. Salazar FJ, Alberola A, Nakamura T, Granger JP. Role of nitric oxide in the renal hemodynamic response to a meta meal. Am J Physiol Regul Integr Comp Physiol 267: R1050-R1055, 1994.
29. Salazar F, Reverte V, Saez F, Loria A, Llinas MT, Salazar FJ. Ageand sodium-sensitive hypertension and sex-dependent renal changes in rats with a reduced nephron number. Hypertension 51: 1184-1189, 2008.
30. Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappel MC. Alterations in circulatory and renal angiotensin-converting enzyme and angiotensinconverting enzyme 2 in fetal programmed hypertension. Hypertension 53: 404-408, 2009.
31. Tang L, Bi J, Valego N, Carey LC, Figueroa JP, Chappell MC, Rose J. Prenatal betamethasone exposure alters renal function in immature sheep: sex-differences in effects. Am J Physiol Regul Integr Comp Physiol 299: R793-R803, 2010.
32. Weinberger MH, Fineberg NS. Sodium and volume sensitivity of blood pressure. Age and pressure change over time. Hypertension 18: 67-71, 1991.
33. Woods LL. Mechanisms of renal hemodynamic regulation in response to protein feeding. Kidney Int 44: 659-675, 1993.
34. Woods LL, Ingelfinger JR, Rasch R. Modest maternal protein restriction fails to program adult hypertension in female rats. Am J Physiol Regul Integr Comp Physiol 289: R1131-R1136, 2005.
35. Yang T, Huang YG, Ye W, Hansen P, Schnermann JB, Briggs JP. Influence of genetic background and gender on hypertension and renal failure in COX2-deficient mice. Am J Physiol Renal Physiol 288: F1125-F1132, 2005.
36. Zandi-Nejad K, Luyckx VA, Brenner BM. Adult hypertension and kidney disease: the role of fetal programming. Hypertension 47: 502-528, 2006.