Sex chromosome effects unmasked in angiotensin II-induced hypertension

Hypertension

Volumn 55, Issue 5, 2010, Pages 1275-1282

  Ji, Hong ^a,b   Zheng, Wei ^a,b   Wu, Xie ^a,b   Liu, Jun ^a   Ecelbarger, Carolyn M ^a,b   Watkins, Rebecca ^c   Arnold, Arthur P ^c   Sandberg, Kathryn ^a,b  

^a Department of Medicine ^*  (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

4 core genotype; Angiotensin II; Hypertension; Sex chromosomes; Sex differences

Indexed keywords

ANGIOTENSIN II;

ANGIOTENSIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; GONADECTOMY; HEART RATE; HYPERTENSION; KARYOTYPE 46,XX; KARYOTYPE 46,XY; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEX CHROMOSOME; SEX DIFFERENCE;

ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; BODY WEIGHT; CROSSES, GENETIC; FEMALE; HEART RATE; HYPERTENSION; MALE; MICE; ORCHIECTOMY; OVARIECTOMY; SEX CHARACTERISTICS; X CHROMOSOME; Y CHROMOSOME;

EID: 77951498389     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.109.144949     Document Type: Article

References (45)

1. Neugarten J, Acharya A, Silbiger SR. Effect of gender on the progression of nondiabetic renal disease: a meta-analysis. J Am Soc Nephrol. 2000; 11:319-329. (Pubitemid 30064855)
2. Kannel WB. The Framingham Study: historical insight on the impact of cardiovascular risk factors in men versus women. J Gend Specif Med. 2002;5:27-37.
3. Burt VL, Whelton P, Roccella EJ, Brown C, Cutler JA, Higgins M, Horan MJ, Labarthe D. Prevalence of hypertension in the US adult population: results from the Third National Health and Nutrition Examination Survey, 1988-1991. Hypertension. 1995;25:305-313.
4. Reckelhoff JF, Zhang H, Granger JP. Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats. Hypertension. 1998;31:435-439. (Pubitemid 28124754)
5. Reckelhoff JF. Gender differences in the regulation of blood pressure. Hypertension. 2001;37:1199-1208. (Pubitemid 34163570)
6. Ouchi Y, Share L, Crofton JT, Iitake K, Brooks DP. Sex difference in the development of deoxycorticosterone-salt hypertension in the rat. Hypertension. 1987;9:172-177. (Pubitemid 17027831)
7. Rowland NE, Fregly MJ. Role of gonadal hormones in hypertension in the Dahl salt-sensitive rat. Clin Exp Hypertens A. 1992;14:367-375.
8. Haywood JR, Hinojosa-Laborde C. Sexual dimorphism of sodium-sensitive renal-wrap hypertension. Hypertension. 1997;30:667-671. (Pubitemid 27444252)
9. Pamidimukkala J, Xue B, Newton LG, Lubahn DB, Hay M. Estrogen receptor-a mediates estrogen facilitation of baroreflex heart rate responses in conscious mice. Am J Physiol Heart Circ Physiol. 2005; 288:H1063-H1070. (Pubitemid 40270008)
10. Arnold AP. Mouse models for evaluating sex chromosome effects that cause sex differences in non-gonadal tissues. J Neuroendocrinol. 2009; 21:377-386.
11. Xue B, Pamidimukkala J, Hay M. Sex differences in the development of angiotensin II-induced hypertension in conscious mice. Am J Physiol Heart Circ Physiol. 2005;288:H2177-H2184. (Pubitemid 40604103)
12. Lovell-Badge R, Robertson E. XY female mice resulting from a heritable mutation in the primary testis-determining gene, Tdy. Development. 1990;109:635-646. (Pubitemid 20228658)
13. Arnold AP, Chen X. What does the "four core genotypes" mouse model tell us about sex differences in the brain and other tissues? Front Neu-roendocrinol. 2009;30:1-9.
14. Soldin SJ, Soldin OP. Steroid hormone analysis by tandem mass spec-trometry. Clin Chem. 2009;55:1061-1066.
15. Welch WJ, Chabrashvili T, Solis G, Chen Y, Gill PS, Aslam S, Wang X, Ji H, Sandberg K, Jose P, Wilcox CS. Role of extracellular superoxide dismutase in the mouse angiotensin slow pressor response [see comment]. Hypertension. 2006;48:934-941. (Pubitemid 44611008)
16. Gurley SB, Allred A, Le TH, Griffiths R, Mao L, Philip N, Haystead TA, Donoghue M, Breitbart RE, Acton SL, Rockman HA, Coffman TM. Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. J Clin Invest. 2006;116:2218-2225. (Pubitemid 44162331)
17. Kawada N, Imai E, Karber A, Welch WJ, Wilcox CS. A mouse model of angiotensin II slow pressor response: role of oxidative stress. J Am Soc Nephrol. 2002;13:2860-2868. (Pubitemid 35386905)
18. De Vries GJ. Sex steroids and sex chromosomes at odds? Endocrinology. 2005;146:3277-3279.
19. Palaszynski KM, Smith DL, Kamrava S, Burgoyne PS, Arnold AP, Voskuhl RR. A yin-yang effect between sex chromosome complement and sex hormones on the immune response. Endocrinology. 2005;146: 3280-3285. (Pubitemid 41058098)
20. Xue B, Johnson AK, Hay M. Sex differences in angiotensin II-induced hypertension. Braz J Med Biol Res. 2007;40:727-734. (Pubitemid 46722220)
21. Yanes LL, Sartori-Valinotti JC, Iliescu R, Romero DG, Racusen LC, Zhang H, Reckelhoff JF. Testosterone-dependent hypertension and upregulation of intrarenal angiotensinogen in Dahl salt-sensitive rats. Am J Physiol Renal Physiol. 2009;296:F771-F779.
22. McGuire JJ, Van Vliet BN, Halfyard SJ. Blood pressures, heart rate and locomotor activity during salt loading and angiotensin II infusion in protease-activated receptor 2 (PAR2) knockout mice. BMC Physiol. 2008;8:20.
23. Narkiewicz K. Obesity and hypertension-the issue is more complex than we thought. Nephrol Dial Transplant. 2006;21:264-267. (Pubitemid 43159976)
24. Krauss RM, Winston M, Fletcher BJ, Grundy SM. Obesity: impact on cardiovascular disease. Circulation. 1998;98:1472-1476. (Pubitemid 28462809)
25. Kurtz TW, Morris RC, Pershadsingh HA. The Zucker fatty rat as a genetic model of obesity and hypertension. Hypertension. 1989;13: 896-901.
26. Dobrian AD, Davies MJ, Prewitt RL, Lauterio TJ. Development of hypertension in a rat model of diet-induced obesity. Hypertension. 2000; 35:1009-1015. (Pubitemid 30303966)
27. Hinojosa-Laborde C, Craig T, Zheng W, Ji H, Haywood JR, Sandberg K. Ovariectomy augments hypertension in aging female Dahl salt-sensitive rats. Hypertension. 2004;44:1-5. (Pubitemid 39281487)
28. Brosnihan KB, Li P, Ganten D, Ferrario CM. Estrogen protects transgenic hypertensive rats by shifting the vasoconstrictor-vasodilator balance of RAS. Am J Physiol. 1997;273:R1908-R1915. (Pubitemid 127752092)
29. Ji H, Menini S, Zheng W, Pesce C, Wu X, Sandberg K. Role of angio-tensin-converting enzyme 2 and angiotensin(1-7) in 17/3-oestradiol regulation of renal pathology in renal wrap hypertension in rats. Exp Physiol. 2008;93:648-657. (Pubitemid 351595057)
30. Ely D, Caplea A, Dunphy G, Daneshvar H, Turner M, Milsted A, Takiyyudin M. Spontaneously hypertensive rat Y chromosome increases indexes of sympathetic nervous system activity. Hypertension. 1997;29: 613-618. (Pubitemid 27074727)
31. Negrin CD, McBride MW, Carswell HV, Graham D, Carr FJ, Clark JS, Jeffs B, Anderson NH, Macrae IM, Dominiczak AF. Reciprocal consomic strains to evaluate y chromosome effects. Hypertension. 2001;37: 391-397. (Pubitemid 32198999)
32. Ely D, Milsted A, Dunphy G, Boehme S, Dunmire J, Hart M, Toot J, Turner M. Delivery of sry1, but not sry2, to the kidney increases blood pressure and sns indices in normotensive wky rats. BMC Physiol. 2009;9:10.
33. Caplea A, Seachrist D, Daneshvar H, Dunphy G, Ely D. Noradrenergic content and turnover rate in kidney and heart shows gender and strain differences. J Appl Physiol. 2002;92:567-571. (Pubitemid 34671021)
34. Uehara Y, Shin WS, Watanabe T, Osanai T, Miyazaki M, Kanase H, Taguchi R, Sugano K, Toyo-Oka T. A hypertensive father, but not hypertensive mother, determines blood pressure in normotensive male offspring through body mass index. J Hum Hypertens. 1998;12:441-445. (Pubitemid 28360711)
35. Lemne CE. Increased blood pressure reactivity in children of borderline hypertensive fathers. J Hypertens. 1998;16:1243-1248.
36. Ellis JA, Stebbing M, Harrap SB. Association of the human Y chromosome with high blood pressure in the general population. Hypertension. 2000;36: 731-733.
37. Charchar FJ, Tomaszewski M, Lacka B, Zakrzewski J, Zukowska-Szczechowska E, Grzeszczak W, Dominiczak AF. Association of the human Y chromosome with cholesterol levels in the general population. Arterioscler Thromb Vasc Biol. 2004;24:308-312. (Pubitemid 38197583)
38. Garcia EC, Gonzalez P, Castro MG, Alvarez R, Reguero JR, Batalla A, Cortina A, Alvarez V. Association between genetic variation in the Y chromosome and hypertension in myocardial infarction patients. Am J Med Genet A. 2003;122:234-237. (Pubitemid 37152869)
39. Carrel L, Willard HF. X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature. 2005;434:400-404. (Pubitemid 40469185)
40. Xu J, Burgoyne PS, Arnold AP. Sex differences in sex chromosome gene expression in mouse brain. Hum Mol Genet. 2002;11:1409-1419. (Pubitemid 34746541)
41. Shih LY, Lin TL, Lai CL, Dunn P, Wu JH, Wang PN, Kuo MC, Lee LC. Predictive values of X-chromosome inactivation patterns and clinicohe-matologic parameters for vascular complications in female patients with essential thrombocythemia. Blood. 2002;100:1596-1601. (Pubitemid 34925134)
42. Demura M, Takeda Y, Yoneda T, Furukawa K, Tachi A, Mabuchi H. Completely skewed X-inactivation in a mentally retarded young female with pseudohypoparathyroidism type IB and juvenile renin-dependent hypertension. J Clin Endocrinol Metab. 2003;88:3043-3049. (Pubitemid 36877470)
43. Davies W, Isles AR, Burgoyne PS, Wilkinson LS. X-linked imprinting: effects on brain and behaviour. Bioessays. 2006;28:35-44.
44. Cooley M, Bakalov V, Bondy CA. Lipid profiles in women with 45, X vs 46, XX primary ovarian failure. JAMA. 2003;290:2127-2128. (Pubitemid 37432971)
45. Migeon B. Females Are Mosaics: X Inactivation and Sex Differences in Disease: New York, NY. Oxford University Press; 2007.