메뉴 건너뛰기




Volumn 64, Issue , 2014, Pages 57-64

The resistance of cortical bone tissue to failure under cyclic loading is reduced with alendronate

Author keywords

Antiresorptives; Atypical fracture; Bone remodeling; Osteocytes; Osteoporosis

Indexed keywords

ALENDRONIC ACID; BONE DENSITY CONSERVATION AGENT;

EID: 84899144899     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2014.03.045     Document Type: Article
Times cited : (46)

References (57)
  • 2
    • 0029884643 scopus 로고    scopus 로고
    • Bisphosphonates: mechanisms of action
    • Rodan G.A., Fleisch H.A. Bisphosphonates: mechanisms of action. J Clin Invest 1996, 97:2692-2696.
    • (1996) J Clin Invest , vol.97 , pp. 2692-2696
    • Rodan, G.A.1    Fleisch, H.A.2
  • 3
    • 0004851872 scopus 로고    scopus 로고
    • Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture intervention trial research group
    • Black D.M., Cummings S.R., Karpf D.B., Cauley J.A., Thompson D.E., Nevitt M.C., et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture intervention trial research group. Lancet 1996, 348:1535-1541.
    • (1996) Lancet , vol.348 , pp. 1535-1541
    • Black, D.M.1    Cummings, S.R.2    Karpf, D.B.3    Cauley, J.A.4    Thompson, D.E.5    Nevitt, M.C.6
  • 4
    • 0034530951 scopus 로고    scopus 로고
    • Fracture risk reduction with alendronate in women with osteoporosis: the fracture intervention trial research group
    • Black D.M., Thompson D.E., Bauer D.C., Ensrud K., Musliner T.A., Hochberg M.C., et al. Fracture risk reduction with alendronate in women with osteoporosis: the fracture intervention trial research group. J Clin Endocrinol Metab 2000, 85:4118-4124.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4118-4124
    • Black, D.M.1    Thompson, D.E.2    Bauer, D.C.3    Ensrud, K.4    Musliner, T.A.5    Hochberg, M.C.6
  • 5
    • 0032583492 scopus 로고    scopus 로고
    • Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the fracture intervention trial
    • Cummings S.R., Black D.M., Thompson D.E., Applegate W.B., Barrett-Connor E., Musliner T.A., et al. Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the fracture intervention trial. JAMA 1998, 280:2077-2082.
    • (1998) JAMA , vol.280 , pp. 2077-2082
    • Cummings, S.R.1    Black, D.M.2    Thompson, D.E.3    Applegate, W.B.4    Barrett-Connor, E.5    Musliner, T.A.6
  • 6
    • 0028851590 scopus 로고
    • Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The alendronate phase III osteoporosis treatment study group
    • Liberman U.A., Weiss S.R., Broll J., Minne H.W., Quan H., Bell N.H., et al. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The alendronate phase III osteoporosis treatment study group. N Engl J Med 1995, 333:1437-1443.
    • (1995) N Engl J Med , vol.333 , pp. 1437-1443
    • Liberman, U.A.1    Weiss, S.R.2    Broll, J.3    Minne, H.W.4    Quan, H.5    Bell, N.H.6
  • 8
    • 45849120957 scopus 로고    scopus 로고
    • Alendronate reduces bone toughness of ribs without significantly increasing microdamage accumulation in dogs following 3years of daily treatment
    • Allen M.R., Reinwald S., Burr D.B. Alendronate reduces bone toughness of ribs without significantly increasing microdamage accumulation in dogs following 3years of daily treatment. Calcif Tissue Int 2008, 82:354-360.
    • (2008) Calcif Tissue Int , vol.82 , pp. 354-360
    • Allen, M.R.1    Reinwald, S.2    Burr, D.B.3
  • 9
    • 84858717807 scopus 로고    scopus 로고
    • Bone micromechanical properties are compromised during long-term alendronate therapy independently of mineralization
    • Bala Y., Depalle B., Farlay D., Douillard T., Meille S., Follet H., et al. Bone micromechanical properties are compromised during long-term alendronate therapy independently of mineralization. J Bone Miner Res 2012, 27:825-834.
    • (2012) J Bone Miner Res , vol.27 , pp. 825-834
    • Bala, Y.1    Depalle, B.2    Farlay, D.3    Douillard, T.4    Meille, S.5    Follet, H.6
  • 10
    • 0033755981 scopus 로고    scopus 로고
    • Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women
    • Boivin G.Y., Chavassieux P.M., Santora A.C., Yates J., Meunier P.J. Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women. Bone 2000, 27:687-694.
    • (2000) Bone , vol.27 , pp. 687-694
    • Boivin, G.Y.1    Chavassieux, P.M.2    Santora, A.C.3    Yates, J.4    Meunier, P.J.5
  • 11
    • 0034906270 scopus 로고    scopus 로고
    • Alendronate increases degree and uniformity of mineralization in cancellous bone and decreases the porosity in cortical bone of osteoporotic women
    • Roschger P., Rinnerthaler S., Yates J., Rodan G.A., Fratzl P., Klaushofer K. Alendronate increases degree and uniformity of mineralization in cancellous bone and decreases the porosity in cortical bone of osteoporotic women. Bone 2001, 29:185-191.
    • (2001) Bone , vol.29 , pp. 185-191
    • Roschger, P.1    Rinnerthaler, S.2    Yates, J.3    Rodan, G.A.4    Fratzl, P.5    Klaushofer, K.6
  • 12
    • 84857340290 scopus 로고    scopus 로고
    • Reduced cortical bone compositional heterogeneity with bisphosphonate treatment in postmenopausal women with intertrochanteric and subtrochanteric fractures
    • Donnelly E., Meredith D.S., Nguyen J.T., Gladnick B.P., Rebolledo B.J., Shaffer A.D., et al. Reduced cortical bone compositional heterogeneity with bisphosphonate treatment in postmenopausal women with intertrochanteric and subtrochanteric fractures. J Bone Miner Res 2012, 27:672-678.
    • (2012) J Bone Miner Res , vol.27 , pp. 672-678
    • Donnelly, E.1    Meredith, D.S.2    Nguyen, J.T.3    Gladnick, B.P.4    Rebolledo, B.J.5    Shaffer, A.D.6
  • 13
    • 38449101476 scopus 로고    scopus 로고
    • Three years of alendronate treatment results in similar levels of vertebral microdamage as after one year of treatment
    • Allen M.R., Burr D.B. Three years of alendronate treatment results in similar levels of vertebral microdamage as after one year of treatment. J Bone Miner Res 2007, 22:1759-1765.
    • (2007) J Bone Miner Res , vol.22 , pp. 1759-1765
    • Allen, M.R.1    Burr, D.B.2
  • 14
    • 77649187517 scopus 로고    scopus 로고
    • Bisphosphonate treatment modifies canine bone mineral and matrix properties and their heterogeneity
    • Gourion-Arsiquaud S., Allen M.R., Burr D.B., Vashishth D., Tang S.Y., Boskey A.L. Bisphosphonate treatment modifies canine bone mineral and matrix properties and their heterogeneity. Bone 2010, 46:666-672.
    • (2010) Bone , vol.46 , pp. 666-672
    • Gourion-Arsiquaud, S.1    Allen, M.R.2    Burr, D.B.3    Vashishth, D.4    Tang, S.Y.5    Boskey, A.L.6
  • 15
    • 33748175899 scopus 로고    scopus 로고
    • Alterations in canine vertebral bone turnover, microdamage accumulation, and biomechanical properties following 1-year treatment with clinical treatment doses of risedronate or alendronate
    • Allen M.R., Iwata K., Phipps R., Burr D.B. Alterations in canine vertebral bone turnover, microdamage accumulation, and biomechanical properties following 1-year treatment with clinical treatment doses of risedronate or alendronate. Bone 2006, 39:872-879.
    • (2006) Bone , vol.39 , pp. 872-879
    • Allen, M.R.1    Iwata, K.2    Phipps, R.3    Burr, D.B.4
  • 16
    • 14644437231 scopus 로고    scopus 로고
    • Suppressed bone turnover by long-term bisphosphonate treatment accumulates microdamage but maintains intrinsic material properties in cortical bone of dog rib
    • Komatsubara S., Mori S., Mashiba T., Li J., Nonaka K., Kaji Y., et al. Suppressed bone turnover by long-term bisphosphonate treatment accumulates microdamage but maintains intrinsic material properties in cortical bone of dog rib. J Bone Miner Res 2004, 19:999-1005.
    • (2004) J Bone Miner Res , vol.19 , pp. 999-1005
    • Komatsubara, S.1    Mori, S.2    Mashiba, T.3    Li, J.4    Nonaka, K.5    Kaji, Y.6
  • 17
    • 0034065559 scopus 로고    scopus 로고
    • Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib
    • Mashiba T., Hirano T., Turner C.H., Forwood M.R., Johnston C.C., Burr D.B. Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res 2000, 15:613-620.
    • (2000) J Bone Miner Res , vol.15 , pp. 613-620
    • Mashiba, T.1    Hirano, T.2    Turner, C.H.3    Forwood, M.R.4    Johnston, C.C.5    Burr, D.B.6
  • 18
    • 0035004850 scopus 로고    scopus 로고
    • Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles
    • Mashiba T., Turner C.H., Hirano T., Forwood M.R., Jacob D.S., Johnston C.C., et al. Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles. Bone 2001, 28:524-531.
    • (2001) Bone , vol.28 , pp. 524-531
    • Mashiba, T.1    Turner, C.H.2    Hirano, T.3    Forwood, M.R.4    Jacob, D.S.5    Johnston, C.C.6
  • 19
    • 67349105623 scopus 로고    scopus 로고
    • Changes in non-enzymatic glycation and its association with altered mechanical properties following 1-year treatment with risedronate or alendronate
    • Tang S.Y., Allen M.R., Phipps R., Burr D.B., Vashishth D. Changes in non-enzymatic glycation and its association with altered mechanical properties following 1-year treatment with risedronate or alendronate. Osteoporos Int 2009, 20:887-894.
    • (2009) Osteoporos Int , vol.20 , pp. 887-894
    • Tang, S.Y.1    Allen, M.R.2    Phipps, R.3    Burr, D.B.4    Vashishth, D.5
  • 20
    • 84860803706 scopus 로고    scopus 로고
    • Relating micromechanical properties and mineral densities in severely suppressed bone turnover patients, osteoporotic patients, and normal subjects
    • Tjhia C.K., Stover S.M., Rao D.S., Odvina C.V., Fyhrie D.P. Relating micromechanical properties and mineral densities in severely suppressed bone turnover patients, osteoporotic patients, and normal subjects. Bone 2012, 51:114-122.
    • (2012) Bone , vol.51 , pp. 114-122
    • Tjhia, C.K.1    Stover, S.M.2    Rao, D.S.3    Odvina, C.V.4    Fyhrie, D.P.5
  • 21
    • 0021960062 scopus 로고
    • Bone remodeling in response to in vivo fatigue microdamage
    • Burr D.B., Martin R.B., Schaffler M.B., Radin E.L. Bone remodeling in response to in vivo fatigue microdamage. J Biomech 1985, 18:189-200.
    • (1985) J Biomech , vol.18 , pp. 189-200
    • Burr, D.B.1    Martin, R.B.2    Schaffler, M.B.3    Radin, E.L.4
  • 22
    • 0036903495 scopus 로고    scopus 로고
    • Bone adaptation to load: microdamage as a stimulus for bone remodelling
    • Lee T.C., Staines A., Taylor D. Bone adaptation to load: microdamage as a stimulus for bone remodelling. J Anat 2002, 201:437-446.
    • (2002) J Anat , vol.201 , pp. 437-446
    • Lee, T.C.1    Staines, A.2    Taylor, D.3
  • 23
    • 66349094278 scopus 로고    scopus 로고
    • Subtrochanteric and diaphyseal femur fractures in patients treated with alendronate: a register-based national cohort study
    • Abrahamsen B., Eiken P., Eastell R. Subtrochanteric and diaphyseal femur fractures in patients treated with alendronate: a register-based national cohort study. J Bone Miner Res 2009, 24:1095-1102.
    • (2009) J Bone Miner Res , vol.24 , pp. 1095-1102
    • Abrahamsen, B.1    Eiken, P.2    Eastell, R.3
  • 24
    • 40949099444 scopus 로고    scopus 로고
    • Atypical fractures of the femoral diaphysis in postmenopausal women taking alendronate
    • Lenart B.A., Lorich D.G., Lane J.M. Atypical fractures of the femoral diaphysis in postmenopausal women taking alendronate. N Engl J Med 2008, 358:1304-1306.
    • (2008) N Engl J Med , vol.358 , pp. 1304-1306
    • Lenart, B.A.1    Lorich, D.G.2    Lane, J.M.3
  • 25
    • 67650468390 scopus 로고    scopus 로고
    • Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study
    • Lenart B.A., Neviaser A.S., Lyman S., Chang C.C., Edobor-Osula F., Steele B., et al. Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study. Osteoporos Int 2009, 20:1353-1362.
    • (2009) Osteoporos Int , vol.20 , pp. 1353-1362
    • Lenart, B.A.1    Neviaser, A.S.2    Lyman, S.3    Chang, C.C.4    Edobor-Osula, F.5    Steele, B.6
  • 27
    • 79951974391 scopus 로고    scopus 로고
    • Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women
    • Park-Wyllie L.Y., Mamdani M.M., Juurlink D.N., Hawker G.A., Gunraj N., Austin P.C., et al. Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women. JAMA 2011, 305:783-789.
    • (2011) JAMA , vol.305 , pp. 783-789
    • Park-Wyllie, L.Y.1    Mamdani, M.M.2    Juurlink, D.N.3    Hawker, G.A.4    Gunraj, N.5    Austin, P.C.6
  • 28
    • 78349249359 scopus 로고    scopus 로고
    • Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral Research
    • Shane E., Burr D., Ebeling P.R., Abrahamsen B., Adler R.A., Brown T.D., et al. Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 2010, 25:2267-2294.
    • (2010) J Bone Miner Res , vol.25 , pp. 2267-2294
    • Shane, E.1    Burr, D.2    Ebeling, P.R.3    Abrahamsen, B.4    Adler, R.A.5    Brown, T.D.6
  • 29
    • 70349907304 scopus 로고    scopus 로고
    • Bilateral fractures of the femur diaphysis in a patient with rheumatoid arthritis on long-term treatment with alendronate: clues to the mechanism of increased bone fragility
    • Somford M.P., Draijer F.W., Thomassen B.J.W., Chavassieux P.M., Boivin G., Papapoulos S.E. Bilateral fractures of the femur diaphysis in a patient with rheumatoid arthritis on long-term treatment with alendronate: clues to the mechanism of increased bone fragility. J Bone Miner Res 2009, 24:1736-1740.
    • (2009) J Bone Miner Res , vol.24 , pp. 1736-1740
    • Somford, M.P.1    Draijer, F.W.2    Thomassen, B.J.W.3    Chavassieux, P.M.4    Boivin, G.5    Papapoulos, S.E.6
  • 32
    • 0017278699 scopus 로고
    • Fatigue life of compact bone-II. Effects of microstructure and density.
    • Carter D.R., Hayes W.C., Schurman D.J. Fatigue life of compact bone-II. Effects of microstructure and density. J Biomech 1976, 9:211-218.
    • (1976) J Biomech , vol.9 , pp. 211-218
    • Carter, D.R.1    Hayes, W.C.2    Schurman, D.J.3
  • 33
    • 0031127010 scopus 로고    scopus 로고
    • Decrease in canine proximal femoral ultimate strength and stiffness due to fatigue damage
    • Hoshaw S.J., Cody D.D., Saad A.M., Fyhrie D.P. Decrease in canine proximal femoral ultimate strength and stiffness due to fatigue damage. J Biomech 1997, 30:323-329.
    • (1997) J Biomech , vol.30 , pp. 323-329
    • Hoshaw, S.J.1    Cody, D.D.2    Saad, A.M.3    Fyhrie, D.P.4
  • 34
    • 0030040334 scopus 로고    scopus 로고
    • Cyclic mechanical property degradation during fatigue loading of cortical bone
    • Pattin C.A., Caler W.E., Carter D.R. Cyclic mechanical property degradation during fatigue loading of cortical bone. J Biomech 1996, 29:69-79.
    • (1996) J Biomech , vol.29 , pp. 69-79
    • Pattin, C.A.1    Caler, W.E.2    Carter, D.R.3
  • 35
    • 0024993392 scopus 로고
    • Long-term fatigue behavior of compact bone at low strain magnitude and rate
    • Schaffler M.B., Radin E.L., Burr D.B. Long-term fatigue behavior of compact bone at low strain magnitude and rate. Bone 1990, 11:321-326.
    • (1990) Bone , vol.11 , pp. 321-326
    • Schaffler, M.B.1    Radin, E.L.2    Burr, D.B.3
  • 36
    • 67349284287 scopus 로고    scopus 로고
    • Systematic error in mechanical measures of damage during four-point bending fatigue of cortical bone
    • Landrigan M.D., Roeder R.K. Systematic error in mechanical measures of damage during four-point bending fatigue of cortical bone. J Biomech 2009, 42:1212-1217.
    • (2009) J Biomech , vol.42 , pp. 1212-1217
    • Landrigan, M.D.1    Roeder, R.K.2
  • 38
    • 84872866350 scopus 로고    scopus 로고
    • Standardized nomenclature, symbols, and units for bone histomorphometry: a 2012 update of the report of the ASBMR histomorphometry nomenclature committee
    • Dempster D.W., Compston J.E., Drezner M.K., Glorieux F.H., Kanis J.A., Malluche H., et al. Standardized nomenclature, symbols, and units for bone histomorphometry: a 2012 update of the report of the ASBMR histomorphometry nomenclature committee. J Bone Miner Res 2013, 28:2-17.
    • (2013) J Bone Miner Res , vol.28 , pp. 2-17
    • Dempster, D.W.1    Compston, J.E.2    Drezner, M.K.3    Glorieux, F.H.4    Kanis, J.A.5    Malluche, H.6
  • 39
    • 84950433002 scopus 로고
    • K-sample Anderson-Darling tests
    • Scholz F.W., Stephens M.A. K-sample Anderson-Darling tests. J Am Stat Assoc 1987, 82:918-924.
    • (1987) J Am Stat Assoc , vol.82 , pp. 918-924
    • Scholz, F.W.1    Stephens, M.A.2
  • 40
    • 20544456605 scopus 로고    scopus 로고
    • Effects of damage morphology on cortical bone fragility
    • Diab T., Vashishth D. Effects of damage morphology on cortical bone fragility. Bone 2005, 37:96-102.
    • (2005) Bone , vol.37 , pp. 96-102
    • Diab, T.1    Vashishth, D.2
  • 41
    • 81355160420 scopus 로고    scopus 로고
    • Mechanical property and tissue mineral density differences among severely suppressed bone turnover (SSBT) patients, osteoporotic patients, and normal subjects
    • Tjhia C.K., Odvina C.V., Sudhaker R.D., Stover S.M., Wang X., Fyhrie D.P. Mechanical property and tissue mineral density differences among severely suppressed bone turnover (SSBT) patients, osteoporotic patients, and normal subjects. Bone 2011, 49:1279-1289.
    • (2011) Bone , vol.49 , pp. 1279-1289
    • Tjhia, C.K.1    Odvina, C.V.2    Sudhaker, R.D.3    Stover, S.M.4    Wang, X.5    Fyhrie, D.P.6
  • 42
    • 0141955302 scopus 로고
    • Human Haversian system measurements
    • Frost H.M. Human Haversian system measurements. Henry Ford Hosp Med Bull 1961, 9:145-147.
    • (1961) Henry Ford Hosp Med Bull , vol.9 , pp. 145-147
    • Frost, H.M.1
  • 43
    • 0021132963 scopus 로고
    • Lamellar bone turnover system and its effector organ
    • Jaworski Z.F. Lamellar bone turnover system and its effector organ. Calcif Tissue Int 1984, 36(S1):S46-S55.
    • (1984) Calcif Tissue Int , vol.36 , Issue.S1
    • Jaworski, Z.F.1
  • 44
    • 0024209735 scopus 로고
    • Composition of the cement line and its possible mechanical role as a local interface in human compact bone
    • Burr D.B., Schaffler M.B., Frederickson R.G. Composition of the cement line and its possible mechanical role as a local interface in human compact bone. J Biomech 1988, 21:939-945.
    • (1988) J Biomech , vol.21 , pp. 939-945
    • Burr, D.B.1    Schaffler, M.B.2    Frederickson, R.G.3
  • 45
    • 49249118532 scopus 로고    scopus 로고
    • The true toughness of human cortical bone measured with realistically short cracks
    • Koester K.J., Ager J.W., Ritchie R.O. The true toughness of human cortical bone measured with realistically short cracks. Nat Mater 2008, 7:672-677.
    • (2008) Nat Mater , vol.7 , pp. 672-677
    • Koester, K.J.1    Ager, J.W.2    Ritchie, R.O.3
  • 46
    • 0018421762 scopus 로고
    • Cement line motion in bone
    • Lakes R., Saha S. Cement line motion in bone. Science 1979, 204:501-503.
    • (1979) Science , vol.204 , pp. 501-503
    • Lakes, R.1    Saha, S.2
  • 47
    • 77953440638 scopus 로고    scopus 로고
    • Dependence of bone yield (volume of bone formed per unit of cement surface area) on resorption cavity size during osteonal remodeling in human rib: implications for osteoblast function and the pathogenesis of age-related bone loss
    • Qiu S., Rao D.S., Palnitkar S., Parfitt A.M. Dependence of bone yield (volume of bone formed per unit of cement surface area) on resorption cavity size during osteonal remodeling in human rib: implications for osteoblast function and the pathogenesis of age-related bone loss. J Bone Miner Res 2010, 25:423-430.
    • (2010) J Bone Miner Res , vol.25 , pp. 423-430
    • Qiu, S.1    Rao, D.S.2    Palnitkar, S.3    Parfitt, A.M.4
  • 48
    • 0041475992 scopus 로고    scopus 로고
    • Reduced iliac cancellous osteocyte density in patients with osteoporotic vertebral fracture
    • Qiu S., Rao D.S., Palnitkar S., Parfitt A.M. Reduced iliac cancellous osteocyte density in patients with osteoporotic vertebral fracture. J Bone Miner Res 2003, 18:1657-1663.
    • (2003) J Bone Miner Res , vol.18 , pp. 1657-1663
    • Qiu, S.1    Rao, D.S.2    Palnitkar, S.3    Parfitt, A.M.4
  • 49
    • 0029609986 scopus 로고
    • Aging and matrix microdamage accumulation in human compact bone
    • Schaffler M.B., Choi K., Milgrom C. Aging and matrix microdamage accumulation in human compact bone. Bone 1995, 17:521-525.
    • (1995) Bone , vol.17 , pp. 521-525
    • Schaffler, M.B.1    Choi, K.2    Milgrom, C.3
  • 50
    • 0343852894 scopus 로고    scopus 로고
    • Microdamage of human cortical bone: incidence and morphology in long bones
    • Norman T.L., Wang Z. Microdamage of human cortical bone: incidence and morphology in long bones. Bone 1997, 20:375-379.
    • (1997) Bone , vol.20 , pp. 375-379
    • Norman, T.L.1    Wang, Z.2
  • 51
    • 33744906749 scopus 로고    scopus 로고
    • Chemical makeup of microdamaged bone differs from undamaged bone
    • Ruppel M.E., Burr D.B., Miller L.M. Chemical makeup of microdamaged bone differs from undamaged bone. Bone 2006, 39(2):318-324.
    • (2006) Bone , vol.39 , Issue.2 , pp. 318-324
    • Ruppel, M.E.1    Burr, D.B.2    Miller, L.M.3
  • 53
    • 79958703451 scopus 로고    scopus 로고
    • Bisphosphonate effects on bone turnover, microdamage, and mechanical properties: what we think we know and what we know that we don't know
    • Allen M.R., Burr D.B. Bisphosphonate effects on bone turnover, microdamage, and mechanical properties: what we think we know and what we know that we don't know. Bone 2011, 49:56-65.
    • (2011) Bone , vol.49 , pp. 56-65
    • Allen, M.R.1    Burr, D.B.2
  • 54
    • 73649094728 scopus 로고    scopus 로고
    • Morphological assessment of basic multicellular unit resorption parameters in dogs shows additional mechanisms of bisphosphonate effects on bone
    • Allen M.R., Erickson A.M., Wang X., Burr D.B., Martin R.B., Hazelwood S.J. Morphological assessment of basic multicellular unit resorption parameters in dogs shows additional mechanisms of bisphosphonate effects on bone. Calcif Tissue Int 2010, 86:67-71.
    • (2010) Calcif Tissue Int , vol.86 , pp. 67-71
    • Allen, M.R.1    Erickson, A.M.2    Wang, X.3    Burr, D.B.4    Martin, R.B.5    Hazelwood, S.J.6
  • 55
    • 0028909290 scopus 로고
    • The effects of risedronate on canine cancellous bone remodeling: three-dimensional kinetic reconstruction of the remodeling site
    • Boyce R.W., Paddock C.L., Gleason J.R., Sletsema W.K., Eriksen E.F. The effects of risedronate on canine cancellous bone remodeling: three-dimensional kinetic reconstruction of the remodeling site. J Bone Miner Res 1995, 10:211-221.
    • (1995) J Bone Miner Res , vol.10 , pp. 211-221
    • Boyce, R.W.1    Paddock, C.L.2    Gleason, J.R.3    Sletsema, W.K.4    Eriksen, E.F.5
  • 56
    • 79955825984 scopus 로고    scopus 로고
    • Cellular mechanisms of bone remodeling
    • Eriksen E.F. Cellular mechanisms of bone remodeling. Rev Endocr Metab Disord 2010, 11:219-227.
    • (2010) Rev Endocr Metab Disord , vol.11 , pp. 219-227
    • Eriksen, E.F.1
  • 57
    • 0013956153 scopus 로고
    • Studies of Haversian systems in man and some animals
    • Jowsey J. Studies of Haversian systems in man and some animals. J Anat 1966, 100:857-864.
    • (1966) J Anat , vol.100 , pp. 857-864
    • Jowsey, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.