Size-dependent internalisation of folate-decorated nanoparticles via the pathways of clathrin and caveolae-mediated endocytosis in ARPE-19 cells

Journal of Pharmacy and Pharmacology

Volumn 66, Issue 4, 2014, Pages 564-573

  Suen, Wai Leung Langston ^a   Chau, Ying ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

inhibition study; pinocytosis; receptor mediated; uptake kinetics

Indexed keywords

INHIBITION STUDY; PINOCYTOSIS; RECEPTOR-MEDIATED; UPTAKE KINETICS;

BETA-CYCLODEXTRINS; CAVEOLAE; CELL LINE; CHLORPROMAZINE; CLATHRIN; ENDOCYTOSIS; FOLIC ACID; HUMANS; KINETICS; NANOPARTICLES; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; RETINAL PIGMENT EPITHELIUM;

EID: 84899106982     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12134     Document Type: Article

References (26)

1. Strauss O,. The retinal pigment epithelium in visual function. Physiol Rev 2005; 85: 845-881.
2. Nowak JZ,. Age-related macular degeneration (AMD): pathogenesis and therapy. Pharmacol Rep 2006; 58: 353-363.
3. Suen WL, Chau Y,. Specific uptake of folate-decorated triamcinolone-encapsulating nanoparticles by retinal pigment epithelium cells enhances and prolongs antiangiogenic activity. J Control Release 2013; 167: 21-28.
4. Conner SD, Schmid SL,. Regulated portals of entry into the cell. Nature 2003; 422: 37-44.
5. Rejman J, etal. Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis. Biochem J 2004; 377 (Pt 1): 159-169.
6. Mukherjee S, etal. Endocytosis. Physiol Rev 1997; 77: 759-803.
7. Parton RG, Simons K,. The multiple faces of caveolae. Nat Rev Mol Cell Biol 2007; 8: 185-194.
8. Bareford LM, Swaan PW,. Endocytic mechanisms for targeted drug delivery. Adv Drug Deliv Rev 2007; 59: 748-758.
9. Bridges CC, etal. A comparison of caveolae and caveolin-1 to folate receptor alpha in retina and retinal pigment epithelium. Histochem J 2001; 33: 149-158.
10. Lauffenburger DA, Linderman JJ,. Receptors: Models for Binding, Trafficking, and Signaling. New York, NY, USA: Oxford University Press, 1992.
11. Li Zhongyu YC,. A facile synthesis of branched poly(ethylene glycol) and its heterobifunctional derivatives. Polymer Chem 2011; 2: 873-878.
12. R. Meier MA, etal. Schubert, PEO-b-PCL Block Copolymers: Synthesis, Detailed Characterization, and Selected Micellar Drug Encapsulation Behavior. Macromol Rapid Commun 2005; 26: 1918-1924.
13. Govender T, etal. PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. J Control Release 1999; 57: 171-185.
14. Vercauteren D, etal. The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls. Mol Ther 2010; 18: 561-569.
15. Bae Y, etal. In vivo antitumor activity of the folate-conjugated pH-Sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments. Bioconjug Chem 2007; 18: 1131-1139.
16. Stella B, etal. Design of folic acid-conjugated nanoparticles for drug targeting. J Pharm Sci 2000; 89: 1452-1464.
17. Chancy CD, etal. Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium. J Biol Chem 2000; 275: 20676-20684.
18. Kamen BA, etal. Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles. J Biol Chem 1988; 263: 13602-13609.
19. Rodman JS, etal. The membrane composition of coated pits, microvilli, endosomes, and lysosomes is distinctive in the rat kidney proximal tubule cell. J Cell Biol 1986; 102: 77-87.
20. Maxfield FR, McGraw TE,. Endocytic recycling. Nat Rev Mol Cell Biol 2004; 5: 121-132.
21. Wang LH, etal. Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation. J Cell Biol 1993; 123: 1107-1117.
22. Rodal SK, etal. Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles. Mol Biol Cell 1999; 10: 961-974.
23. Zuhorn IS, etal. Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis. J Biol Chem 2002; 277: 18021-18028.
24. Zuhorn IS, etal. Interference of serum with lipoplex-cell interaction: modulation of intracellular processing. Biochim Biophys Acta 2002; 1560: 25-36.
25. Ross PC, Hui SW,. Lipoplex size is a major determinant of in vitro lipofection efficiency. Gene Ther 1999; 6: 651-659.
26. Shin JS, Abraham SN,. Caveolae as portals of entry for microbes. Microbes Infect 2001; 3: 755-761.