Protective effect of lutein against benzo(a)pyrene-induced oxidative stress in human erythrocytes

Toxicology and Industrial Health

Volumn 30, Issue 3, 2014, Pages 284-293

  Vijayapadma, Viswanadha ^a   Ramyaa, Periasamy ^a   Pavithra, Dhayalan ^b   Krishnasamy, Rajashree ^c  

^a BHARATHIAR UNIVERSITY   (India)

^b PSG COLLEGE OF TECHNOLOGY   (India)

^c KUMARAGURU COLLEGE OF TECHNOLOGY   (India)

Author keywords

antioxidant enzymes; benzo(a)pyrene; erythrocytes; free radical; lutein; oxidative stress; Polycyclic aromatic hydrocarbons

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BENZO[A]PYRENE; CARBONYL DERIVATIVE; DNA; METHEMOGLOBIN; THIOL GROUP; XANTHOPHYLL; OXIDOREDUCTASE;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPID PEROXIDATION; MACROMOLECULE; NORMAL HUMAN; OXIDATION; OXIDATIVE STRESS; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; TOXICITY;

ANTIOXIDANTS; BENZO(A)PYRENE; ERYTHROCYTES; HUMANS; LUTEIN; METHEMOGLOBIN; OXIDATIVE STRESS; OXIDOREDUCTASES;

EID: 84899103734     PISSN: 07482337     EISSN: 14770393     Source Type: Journal    
DOI: 10.1177/0748233712457439     Document Type: Article

References (56)

1. Abraham S, Soundararajan CC, Vivekanandhan S et al. (2005) Erythrocyte antioxidant enzymes in Parkinson's disease. Indian Journal Medical Research 121: 111–115.
2. Aebi H (1984) Catalase in vitro. Methods of Enzymology 105: 121–126.
3. Ajila CM, Prasada Rao UJS (2008) Protection against hydrogen peroxide induced oxidative damage in rat erythrocytes by Mangifera indica L. peel extract. Food and Chemical Toxicology 46: 303–309.
4. Aktan B, Taysi S, Gumustekin K et al. (2003) Evaluation of oxidative stress in erythrocytes of guinea pigs with experimental otitis media and effusion. Annals of Clinical and Laboratory Science 33: 232–236.
5. Alanazi FK (2010) Pravastatin provides antioxidant activity and protection of erythrocytes loaded primaquine. International Journal of Medical Sciences 7: 358–365.
6. Alexandrova ML, Bochev PG (2009) Reduced extracellular phagocyte oxidative activity, antioxidant level changes and increased oxidative damage in healthy human blood as a function of age. Age 31: 99–107.Amresh G, Kant R, Rao V, et al. (2007) Chemomodulatory influence of Cissampelos pareira (L.) Hirsuta on gastric cancer and antioxidant system in experimental animal. Acta Pharmaceutica Sciencia 49: 71–83.
7. Bukowska B, Kowalska S (2004) Phenol and catechol induce prehemolytic and hemolytic changes in human erythrocytes. Toxicology Letters 152: 73–84.
8. Chan JY, Kwong M, Lo M et al. (2001) Reduced oxidative-stress response in red blood cells from p45NFE2-deficient mice. Blood 97: 2151–2158.
9. Connor O, Brien NO (1998) Modulation of UVA light-induced oxidative stress by [beta]-carotene, lutein and astaxanthin in cultured fibroblasts. Journal of Dermatological Science 16 (3): 226–230.
10. Drabkin DL, Austin JM (1932). Spectrophotometric constants for common hemoglobin derivatives in human, dog and rabbit blood. Journal of Biological Chemistry 98: 719–733.
11. Durak D, Kalender S, Uzun FG et al. (2010) Mercury chloride-induced oxidative stress in human erythrocytes and the effect of vitamins C and E in vitro. African Journal of Biotechnology 9: 488–495.
12. Evelyn K, Malloy H (1938) Micro determination of oxyhaemoglobin, methaemoglobin and sulfhaemoglobin in a single sample of blood. Journal of Biological Chemistry 126: 655–662.
13. Fukuda I, Sakane I, Yabushita Y et al. (2004) Pigments in green tea leaves (Camellia sinensis) suppress transformation of the aryl hydrocarbon receptor induced by dioxin. Journal of Agricultural and Food Chemistry 52: 2499–2506.
14. Gangar SC, Sandhir R, Rai DV et al. (2006) Modulatory effects of Azadirachta indica on benzo(a)pyrene-induced forestomach tumorigenesis in mice. World Journal of Gastroenterology 12(17): 2749–2755.
15. Gangar SC, Sandhir R, Rai DV et al. (2010) Anti-clastogenic activity of Azadirachta indica against benzo(a)pyrene in murine forestomach tumorigenesis bioassay. Acta Poloniae Pharmaceutica in Drug Research 67: 381–390.
16. Grzelak A, Kruszewski M, Macierzynska E et al. (2009) The effects of superoxide dismutase knockout on the oxidative stress parameters and survival of mouse erythrocytes. Cellular and Molecular Biology Letters 14: 23–34.
17. Habig WH, Jakoby WB (1981) Assays for the differentiation of glutathione S-transferase. Methods in Enzymology 77(6): 398–405.
18. Hemalatha A, Venkatesan A, Bobby Z et al. (2006) Antioxidant response to oxidative stress induced by smoking. Indian Journal of Physiology and Pharmacology 50(4): 416–420.
19. Hougland MW, Luethke JM (1982) Quantitation of sulfhydryl groups on erythrocytes in polycythemia vera. Histochemistry 76(1): 57–60.
20. Kim HS, Kwack SJ, Lee BM (2000) Lipid peroxidation, antioxidant enzymes, and benzo[a]pyrene-quinones in the blood of rats treated with benzo(a)pyrene. Chemico-Biological Interactions 127(2): 139–150.
21. Ra Kim So, Nakanishi Koji, Itagaki Yasuhiro et al. (2006) Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin. Experimental Eye Research 82(5): 828–839.
22. 2 in NF-[kappa]B activation. Free Radical Biology and Medicine 4 5(6): 885–896.
23. Kiruthiga PV, Pandian SK, Devi KP (2010) Silymarin protects PBMC against B(a)P induced toxicity by replenishing redox status and modulating glutathione metabolizing enzymes- an in vitro study. Toxicology and Applied Pharmacology 247(2): 116–128.
24. 2 exposure in erythrocytes. Basic and Clinical Pharmacology and Toxicology 100: 414–419.
25. 2) induced oxidative stress. Chemosphere 68: 1511–1518.
26. Krishnaswamy R, Devaraj SN, Padma VV (2010) Lutein protects HT-29 cells against Deoxynivalenol-induced oxidative stress and apoptosis: prevention of NF-[kappa]B nuclear localization and down regulation of NF-[kappa]B and Cyclo-Oxygenase - 2 expression. Free Radical Biology and Medicine 49(1): 50–60.
27. Lee SK, Lee BM (1997) Oxidation of erythrocyte protein and lipid, and hemolysis in rabbit red blood cells treated with benzo(a)pyrene or adriamycin. Journal of Toxicology and Environmental Health 51: 557–569.
28. Levine RL, Garland D, Oliver CN (1990) Determination of carbonylcontent in oxidatively modified proteins. Methods in Enzymology 186: 464–478.
29. Li SY, Lo ACY (2010) Lutein protects RGC-5 cells against hypoxia and oxidative stress. International Journal of Molecular Sciences 11(5): 2109–2117.
30. Lo Jacono F, Stecca C, Duverger M (1992) Mutagenic activation of benzo(a)pyrene by human red blood cells. Mutation Research/Fundamental and Molecular Mechanisms of mutagenesis 268: 21–26.
31. Lowry OH, Rosebrough NJ, Farr AL et al. (1951) Protein measurement with the folin phenol reagent. Journal of Biological Chemistry 193: 265–275.
32. Lukyanenko LM, Kozlova NM, Slobozhanina EI (2004) Activity of membrane-bound NADH-methemoglobin reductase and physical state of lipids in erythrocyte membranes. Bioelectrochemistry 62(2): 191–193.
33. Magesh V, Singh J, Selvendiran K et al. (2006) Antitumour activity of crocetin in accordance to tumor incidence, antioxidant status, drug metabolizing enzymes and histopathological studies. Molecular and Cellular Biochemistry 287(1): 127–135.
34. Magesh V, Venugopal R, Bhavani KD et al. (2007) Effect of crocetin on benzopyrene induced lung carcnogenesis in swiss albino mice. International Journal of Cancer Research 3: 143–150.
35. Mann KK, Matulka RA, Hahn ME et al. (1999) The role of polycyclic aromatic hydrocarbon metabolism in dimethylbenz[a]anthracene-induced pre-B lymphocyte apoptosis. Toxicology and Applied Pharmacology 161(1): 10–22.
36. Marklund S, Marklund D (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. European Journal Of Biochemistry 47: 469–474.
37. Maurya PK, Kumar P, Siddiqui N et al. (2010) Age-associated changes in erythrocyte glutathione peroxidase activity: correlation with total antioxidant potential. Indian Journal of Biochemistry & Biophysics 47(5): 319–321.
38. McCord JM, Fridovich I (1969) Superoxide dismutase – An enzyme function for erythrocuprein (haemocuprein). Journal of Biological Chemistry 244: 6049–655.
39. Moron MJ, Dipierre JW, Mannervik B (1979) Levels of glutathione reductase and glutathione-s-transferase activities in rat lung and liver. Biochimica et Biophysica Acta 582: 67–68.
40. Nakagawa K, Kiko T, Hatade K et al. (2009) Antioxidant effect of lutein towards phospholipid hydroperoxidation in human erythrocytes. British Journal of Nutrition 102(9): 1280–1284.
41. Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry 95: 351–358.
42. Pandey KP, Rizvi SI (2010) Protection of protein carbonyl formation by quercetin in erythrocytes subjected to oxidative stress. Medical Chemistry Research 19: 186–192.
43. Penning TM, Ohnishi ST, Ohnishi T, Harvey RG (1996). Generation of reactive oxygen species during the enzymatic oxidation of polycyclic aromatic hydrocarbon trans-dihydrodiols catalyzed by dihydrodiol dehydrogenase. Chemical Research in Toxicology 9: 84–92.
44. Qujeq D, Habibinudeh M, Daylmkatoli M et al. (2005) Malondialdehyde and carbonyl contents in the erythrocytes of streptozotocin-induced diabetic rats. International Journal of Diabetes and Metabolism 13: 96–98.
45. Ramesh A, Knuckles ME (2006) Dose-dependent benzo(a)pyrene [B(a)P]-DNA adduct levels and persistence in F-344 rats following subchronic dietary exposure to B(a)P. Cancer Letters 240(2): 268–278.
46. Rotruck JT, Pope AL, Ganther HE et al. (1973) Selenium: biochemical role as a component of glutathione peroxidase. Science 179: 588–590.
47. Samarth RM, Panwar M, Kumar M et al. (2006) Protective effects of mentha piperita linn on benzo(a)pyrene-induced lung carcinogenicity and mutagenicity in Swiss albino mice. Mutagenesis 21(1): 61–66.
48. Santocono M, Zurria M, Berrettini M et al. (2006) Influence of astaxanthin, zeaxanthin and lutein on DNA damage and repair in UVA-irradiated cells. Journal of Photochemistry and Photobiology B: Biology 85(3): 205–215.
49. Santocono M, Zurria M, Berrettini M et al., (2007) Lutein, zeaxanthin and astaxanthin protect against DNA damage in SK-N-SH human neuroblastoma cells induced by reactive nitrogen species. Journal of Photochemistry and Photobiology B: Biology 88(1): 1–10.
50. Sedlak J, Lindsay RH (1968) Estimation of total protein-bound and non-protein sulfhydryl groups in tissue with Ellman's reagent. Analytical Biochemistry 25: 192–205.
51. Sindhu ER, Preethi KC, Kuttan R (2010) Antioxidant activity of carotenoid lutein invitro and invivo. Indian Journal of Experimental Biology 48: 843–848.
52. Trevithick JR, Trevithick-Sutton CC, Dzialoszynski T et al. (2005) Radical scavenging by lutein and related carotenoids may contribute to risk eduction of AMD and cataract. Investigative Ophthalmology and Visual Science 46(5): 3855.
53. Uno S, Makishima M (2009) Benzo(a)pyrene toxicity and inflammatory disease. Current Rheumatology Review 5: 266–271.
54. Vani R, Reddy CSS, Devi AS (2010) Oxidative stress in erythrocytes: a study on the effect of antioxidant mixtures during intermittent exposures to high altitude. International Journal of Biometeorology 54: 553–562.
55. Wang M, Tsao R, Zhang S et al. (2006) Antioxidant activity, mutagenicity/anti-mutagenicity, and clastogenicity/anti-clastogenicity of lutein from marigold flowers. Food and Chemical Toxicology 44: 1522–1529.
56. Weinstein IB, Jeffrey AM, Jennette KW et al. (1976). Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo. Science 193: 592–595.