-
1
-
-
34547673400
-
Applying the discovery of the Philadelphia chromosome
-
Sherbenou DW, Druker BJ. Applying the discovery of the Philadelphia chromosome. J Clin Invest 2007; 117: 2067-2074.
-
(2007)
J Clin Invest
, vol.117
, pp. 2067-2074
-
-
Sherbenou, D.W.1
Druker, B.J.2
-
3
-
-
33845444046
-
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
-
Druker BJ, Guilhot F, O'Brien SG, et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 2006; 355: 2408-2417.
-
(2006)
N Engl J Med
, vol.355
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
-
4
-
-
33747154547
-
Evolving concepts in the management of chronic myeloid leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet
-
Baccarani M, Saglio G, Goldman J, et al. Evolving concepts in the management of chronic myeloid leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet. Blood 2006; 108: 1809-1820.
-
(2006)
Blood
, vol.108
, pp. 1809-1820
-
-
Baccarani, M.1
Saglio, G.2
Goldman, J.3
-
5
-
-
73349122639
-
Chronic myeloid leukemia: An update of concepts and management recommendations of European LeukemiaNet
-
Baccarani M, Cortes J, Pane F, et al. Chronic myeloid leukemia: An update of concepts and management recommendations of European LeukemiaNet. J Clin Oncol 2009; 27: 6041-6051.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6041-6051
-
-
Baccarani, M.1
Cortes, J.2
Pane, F.3
-
6
-
-
33947356135
-
Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in blast crisis
-
Cortes J, Rousselot P, Kim DW, et al. Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in blast crisis. Blood 2007; 109: 3207-3213.
-
(2007)
Blood
, vol.109
, pp. 3207-3213
-
-
Cortes, J.1
Rousselot, P.2
Kim, D.W.3
-
7
-
-
34248324467
-
Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase
-
Guilhot F, Apperley J, Kim DW, et al. Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase. Blood 2007; 109: 4143-4150.
-
(2007)
Blood
, vol.109
, pp. 4143-4150
-
-
Guilhot, F.1
Apperley, J.2
Kim, D.W.3
-
8
-
-
33947280081
-
Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy
-
Hochhaus A, Kantarjian HM, Baccarani M, et al. Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy. Blood 2007; 109: 2303-2309.
-
(2007)
Blood
, vol.109
, pp. 2303-2309
-
-
Hochhaus, A.1
Kantarjian, H.M.2
Baccarani, M.3
-
9
-
-
34249074686
-
Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia after failure of first-line imatinib: A randomized phase 2 trial
-
Kantarjian H, Pasquini R, Hamerschlak N, et al. Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia after failure of first-line imatinib: A randomized phase 2 trial. Blood 2007; 109: 5143-5150.
-
(2007)
Blood
, vol.109
, pp. 5143-5150
-
-
Kantarjian, H.1
Pasquini, R.2
Hamerschlak, N.3
-
10
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
Talpaz M, Shah NP, Kantarjian H, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006; 354: 2531-2541.
-
(2006)
N Engl J Med
, vol.354
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
-
11
-
-
34548097263
-
The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib
-
Hantschel O, Rix U, Schmidt U, et al. The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib. Proc Natl Acad Sci USA 2007; 104: 13283-13288.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13283-13288
-
-
Hantschel, O.1
Rix, U.2
Schmidt, U.3
-
12
-
-
37049014938
-
Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets
-
Rix U, Hantschel O, Durnberger G, et al. Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets. Blood 2007; 110: 4055-4063.
-
(2007)
Blood
, vol.110
, pp. 4055-4063
-
-
Rix, U.1
Hantschel, O.2
Durnberger, G.3
-
13
-
-
45449102076
-
The Src/ABL kinase inhibitor dasatinib (BMS-354825) inhibits function of normal human T-lymphocytes in vitro
-
Blake S, Hughes TP, Mayrhofer G, Lyons AB. The Src/ABL kinase inhibitor dasatinib (BMS-354825) inhibits function of normal human T-lymphocytes in vitro. Clin Immunol 2008; 127: 330-339.
-
(2008)
Clin Immunol
, vol.127
, pp. 330-339
-
-
Blake, S.1
Hughes, T.P.2
Mayrhofer, G.3
Lyons, A.B.4
-
14
-
-
52049085750
-
Dasatinib exerts an immunosuppressive effect on CD8+ T cells specific for viral and leukemia antigens
-
Fei F, Yu Y, Schmitt A, et al. Dasatinib exerts an immunosuppressive effect on CD8+ T cells specific for viral and leukemia antigens. Exp Hematol 2008; 36: 1297-1308.
-
(2008)
Exp Hematol
, vol.36
, pp. 1297-1308
-
-
Fei, F.1
Yu, Y.2
Schmitt, A.3
-
15
-
-
38949210227
-
Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation
-
Schade AE, Schieven GL, Townsend R, et al. Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation. Blood 2008; 111: 1366-1377.
-
(2008)
Blood
, vol.111
, pp. 1366-1377
-
-
Schade, A.E.1
Schieven, G.L.2
Townsend, R.3
-
16
-
-
58149267985
-
Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia
-
Kim DH, Kamel-Reid S, Chang H, et al. Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia. Haematologica 2009; 94: 135-139.
-
(2009)
Haematologica
, vol.94
, pp. 135-139
-
-
Kim, D.H.1
Kamel-Reid, S.2
Chang, H.3
-
17
-
-
68749108104
-
Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
-
Mustjoki S, Ekblom M, Arstila TP, et al. Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. Leukemia 2009; 23: 1398-1405.
-
(2009)
Leukemia
, vol.23
, pp. 1398-1405
-
-
Mustjoki, S.1
Ekblom, M.2
Arstila, T.P.3
-
18
-
-
77956280601
-
Mono/oligoclonal T- and NK-cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy
-
Kreutzman A, Juvonen V, Kairisto V, et al. Mono/oligoclonal T- and NK-cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy. Blood 2010; 115: 772-782.
-
(2010)
Blood
, vol.115
, pp. 772-782
-
-
Kreutzman, A.1
Juvonen, V.2
Kairisto, V.3
-
20
-
-
79953064064
-
Prevalence of large granular lymphocyte proliferation in chronic myeloid leukemia (CML) patients treated with Dasatinib
-
Abstract 1111.
-
Schiffer CA, Valent J. Prevalence of large granular lymphocyte proliferation in chronic myeloid leukemia (CML) patients treated with Dasatinib. Blood (ASH Annual Meeting Abstracts) 2009; 114: Abstract 1111.
-
(2009)
Blood (ASH Annual Meeting Abstracts)
, vol.114
-
-
Schiffer, C.A.1
Valent, J.2
-
21
-
-
79952788297
-
Lymphocytosis following treatment with dasatinib is associated with improved response and outcome
-
Abstract 6553.
-
Schiffer CA, Cortes JE, Saglio G, et al. Lymphocytosis following treatment with dasatinib is associated with improved response and outcome. J Clin Oncol (Meeting Abstracts) 2010; 28: Abstract 6553.
-
(2010)
J Clin Oncol (Meeting Abstracts)
, vol.28
-
-
Schiffer, C.A.1
Cortes, J.E.2
Saglio, G.3
-
23
-
-
73949105873
-
Dasatinib treatment of chronic-phase chronic myeloid leukemia: Analysis of responses according to preexisting BCR-ABL mutations
-
Muller MC, Cortes JE, Kim DW, et al. Dasatinib treatment of chronic-phase chronic myeloid leukemia: Analysis of responses according to preexisting BCR-ABL mutations. Blood 2009; 114: 4944-4953.
-
(2009)
Blood
, vol.114
, pp. 4944-4953
-
-
Muller, M.C.1
Cortes, J.E.2
Kim, D.W.3
-
24
-
-
34548523623
-
Pleural effusion in patients with chronic myelogenous leukemia treated with dasatinib after imatinib failure
-
Quintas-Cardama A, Kantarjian H, O'Brien S, et al. Pleural effusion in patients with chronic myelogenous leukemia treated with dasatinib after imatinib failure. J Clin Oncol 2007; 25: 3908-3914.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3908-3914
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
O'Brien, S.3
-
25
-
-
49249121723
-
Intermittent target inhibition with dasatinib 100 mg once daily preserves efficacy and improves tolerability in imatinib-resistant and -intolerant chronic-phase chronic myeloid leukemia
-
Shah NP, Kantarjian HM, Kim DW, et al. Intermittent target inhibition with dasatinib 100 mg once daily preserves efficacy and improves tolerability in imatinib-resistant and -intolerant chronic-phase chronic myeloid leukemia. J Clin Oncol 2008; 26: 3204-3212.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3204-3212
-
-
Shah, N.P.1
Kantarjian, H.M.2
Kim, D.W.3
-
26
-
-
77954536015
-
Clinical features of dasatinib-induced large granular lymphocytosis and pleural effusion
-
Nagata Y, Ohashi K, Fukuda S, et al. Clinical features of dasatinib-induced large granular lymphocytosis and pleural effusion. Int J Hematol 2010; 91: 799-807.
-
(2010)
Int J Hematol
, vol.91
, pp. 799-807
-
-
Nagata, Y.1
Ohashi, K.2
Fukuda, S.3
-
27
-
-
43449091001
-
Pleural effusions in patients with chronic myeloid leukaemia treated with dasatinib may have an immune-mediated pathogenesis
-
de Lavallade H, Punnialingam S, Milojkovic D, et al. Pleural effusions in patients with chronic myeloid leukaemia treated with dasatinib may have an immune-mediated pathogenesis. Br J Haematol 2008; 141: 745-747.
-
(2008)
Br J Haematol
, vol.141
, pp. 745-747
-
-
de Lavallade, H.1
Punnialingam, S.2
Milojkovic, D.3
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