Fall risk-increasing drugs and falls: A cross-sectional study among elderly patients in primary care

BMC Geriatrics

Volumn 14, Issue 1, 2014, Pages

  Milos, Veronica ^a   Bondesson, Åsa ^a,b   Magnusson, Martina ^c   Jakobsson, Ulf ^a   Westerlund, Tommy ^d   Midlöv, Patrik ^a  

^a LUND UNIVERSITY   (Sweden)

^b Lund University   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Drug therapy; Elderly; Fall risk increasing drugs; Falls; Prevention

Indexed keywords

ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; NARCOTIC ANALGESIC AGENT; PSYCHOTROPIC AGENT;

AGED; ARTICLE; CROSS-SECTIONAL STUDY; FALLING; FEMALE; HOME FOR THE AGED; HUMAN; MALE; METHODOLOGY; NURSING HOME; PRIMARY HEALTH CARE; SWEDEN; VERY ELDERLY;

ACCIDENTAL FALLS; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; CROSS-SECTIONAL STUDIES; FEMALE; HOMES FOR THE AGED; HUMANS; MALE; NURSING HOMES; PRIMARY HEALTH CARE; PSYCHOTROPIC DRUGS; SWEDEN;

EID: 84899092241     PISSN: None     EISSN: 14712318     Source Type: Journal    
DOI: 10.1186/1471-2318-14-40     Document Type: Article

References (40)

1. Indikatorer för god läkemedelsterapi hos äldre. Fastbom J, Schmidt I, The Swedish National Board for Health and Welfare 2010 In Swedish. [ http://www.socialstyrelsen.se/publikationer2010/2010-6-29 ]
2. Multi-dose drug dispensing and inappropriate drug use: A nationwide register-based study of over 700,000 elderly. Johnell K, Fastbom J, Scand J Prim Health Care 2008 26 2 86 91 10.1080/02813430802022196 18570006
3. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. Lazarou J, Pomeranz BH, Corey PN, JAMA 1998 279 15 1200 1205 10.1001/jama.279.15.1200 9555760
4. Hospitalisations caused by adverse drug reactions (ADR): a meta-analysis of observational studies. Beijer HJ, de Blaey CJ, Pharm World Sci 2002 24 2 46 54 10.1023/A:1015570104121 12061133
5. Major Injury Hospitalizations Due to Unintentional Falls in Canada 2009-2010. Report. Major Injury Hospitalizations Due to Unintentional Falls in Canada 2009-2010. Report [ https://secure.cihi.ca/estore/productSeries.htm?pc= PCC46 ]
6. Emergency Department Visits for Injurious Falls among the Elderly. Owens PL RC, Spector W, Mutter R, Healthcare Cost and Utilization Project (HCUP) Statistical Briefs 2006
7. Treatment with fall-risk-increasing and fracture-preventing drugs before and after a hip fracture: an observational study. Sjoberg C, Edward C, Bladh L, Klintberg L, Mellstrom D, Ohlsson C, Wallerstedt SM, Drugs Aging 2010 27 8 653 661 10.2165/11538200-000000000-00000 20658793
8. Development of a common outcome data set for fall injury prevention trials: the Prevention of Falls Network Europe consensus. Lamb SE, Jorstad-Stein EC, Hauer K, Becker C, J Am Geriatr Soc 2005 53 9 1618 1622 10.1111/j.1532-5415.2005.53455.x 16137297
9. Development and evaluation of evidence based risk assessment tool (STRATIFY) to predict which elderly inpatients will fall: case-control and cohort studies. Oliver D, Britton M, Seed P, Martin FC, Hopper AH, BMJ 1997 315 7115 1049 1053 10.1136/bmj.315.7115.1049 9366729
10. How to try this: predicting patient falls. Using the Hendrich II Fall Risk Model in clinical practice. Hendrich A, Am J Nurs 2007 107 11 50 58 quiz 58-59 10.1097/01.NAJ.0000298062.27349.8e
11. Examination of validity of fall risk assessment items for screening high fall risk elderly among the healthy community-dwelling Japanese population. Demura S, Sato S, Yamaji S, Kasuga K, Nagasawa Y, Arch Gerontol Geriatr 2011 53 1 41 e45 10.1016/j.archger.2010.10.010 21056480
12. Prevalence, characteristics and factors associated with falls among the elderly living at home. Downton JH, Andrews K, Aging (Milano) 1991 3 3 219 228 1764490
13. Falls, depression and antidepressants in later life: a large primary care appraisal. Kerse N, Flicker L, Pfaff JJ, Draper B, Lautenschlager NT, Sim M, Snowdon J, Almeida OP, PLoS One 2008 3 6 2423 10.1371/journal.pone.0002423 18560599
14. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. American Geriatrics Society 2012 Beers Criteria Update Expert Panel, J Am Geriatr Soc 2012 60 4 616 631 22376048
15. Potentially inappropriate medications in the elderly: a French consensus panel list. Laroche ML, Charmes JP, Merle L, Eur J Clin Pharmacol 2007 63 8 725 731 10.1007/s00228-007-0324-2 17554532
16. Relationship between the risk of falling and drugs in an academic hospital. Tanaka M, Suemaru K, Ikegawa Y, Tabuchi N, Araki H, Yakugaku Zasshi 2008 128 9 1355 1361 10.1248/yakushi.128.1355 18758151
17. Central nervous system-active medications and risk for falls in older women. Ensrud KE, Blackwell TL, Mangione CM, Bowman PJ, Whooley MA, Bauer DC, Schwartz AV, Hanlon JT, Nevitt MC, J Am Geriatr Soc 2002 50 10 1629 1637 10.1046/j.1532-5415.2002.50453.x 12366615
18. The influence of drug use on fall incidents among nursing home residents: a systematic review. Sterke CS, Verhagen AP, van Beeck EF, van der Cammen TJ, Int Psychogeriatr 2008 20 5 890 910 18416875
19. [Medication and falls in old age]. Modreker MK, von Renteln-Kruse W, Internist (Berl) 2009 50 4 493 500 10.1007/s00108-009-2355-5 19300975
20. Medications prescribed and occurrence of falls in general medicine inpatients. Cashin RP, Yang M, Can J Hosp Pharm 2011 64 5 321 326 22479083
21. Interventions for preventing falls in older people living in the community. Gillespie LD, Robertson MC, Gillespie WJ, Lamb SE, Gates S, Cumming RG, Rowe BH, Cochrane Database Syst Rev 2009 2 D007146 19370674
22. The effect of medication reconciliation in elderly patients at hospital discharge. Midlov P, Bahrani L, Seyfali M, Hoglund P, Rickhag E, Eriksson T, Int J Clin Pharm 2012 34 1 113 119 10.1007/s11096-011-9599-6 22207271
23. What are the benefits of multi-dose drug dispensing compared with ordinary prescriptions? [Vilken nytta har ApoDos jämfört med läkemedelshantering baserad på traditionell receptförskrivning?] . Nordling S, Carlsten A, Ragnarson Tennvall G, The Swedish Institute for Health Economics 2009 In Swedish. [ http://www.ihe.se/getfile.aspx?id=1323 ]
24. Improving the quality of pharmacotherapy in elderly primary care patients through medication reviews: a randomised controlled study. Milos V, Rekman E, Bondesson A, Eriksson T, Jakobsson U, Westerlund T, Midlov P, Drugs Aging 2013 30 4 235 246 10.1007/s40266-013-0057-0 23408163
25. PHASE-20: a new instrument for assessment of possible therapeutic drug-related symptoms among elderly in nursing homes [Norwegian]. Hedström MLB, Hulter Åsberg K, Nord J Nurs Res Clin Stud / Vård i Norden (VARD I NORDEN) 2009 29 4 9 14
26. Anatomical Therapeutic Chemical (ATC) Classification Index. Anatomical Therapeutic Chemical (ATC) Classification Index, [ http://www.whocc.no/atcddd ]
27. Risk of falls after withdrawal of fall-risk-increasing drugs: a prospective cohort study. van der Velde N, Stricker BH, Pols HA, van der Cammen TJ, Br J Clin Pharmacol 2007 63 2 232 237 10.1111/j.1365-2125.2006.02736.x 16939531
28. Global Report in Falls Prevention in Older Age. WHO, 2007 [ http://www.who.int/ageing/publications/Falls-prevention7March.pdf ]
29. Inappropriate medication use and risk of falls-a prospective study in a large community-dwelling elderly cohort. Berdot S, Bertrand M, Dartigues JF, Fourrier A, Tavernier B, Ritchie K, Alperovitch A, BMC Geriatr 2009 9 30 10.1186/1471-2318-9-30 19627577
30. Withdrawal of fall-risk-increasing drugs in older persons: effect on tilt-table test outcomes. van der Velde N, van den Meiracker AH, Pols HA, Stricker BH, van der Cammen TJ, J Am Geriatr Soc 2007 55 5 734 739 10.1111/j.1532-5415.2007.01137.x 17493193
31. A Quality Use of Medicines program for general practitioners and older people: a cluster randomised controlled trial. Pit SW, Byles JE, Henry DA, Holt L, Hansen V, Bowman DA, Med J Aust 2007 187 1 23 30 17605699
32. Improving medication use in newly admitted home healthcare patients: a randomized controlled trial. Meredith S, Feldman P, Frey D, Giammarco L, Hall K, Arnold K, Brown NJ, Ray WA, J Am Geriatr Soc 2002 50 9 1484 1491 10.1046/j.1532-5415.2002.50402.x 12383144
33. A screening tool with five risk factors was developed for fall-risk prediction in community-dwelling elderly. Bongue B, Dupré C, Beauchet O, Rossat A, Fantino B, Colvez A, J Clin Epidemiol 2011 64 10 1152 1160 10.1016/j.jclinepi.2010.12.014 21463927
34. Risk factors for serious injury during falls by older persons in the community. Tinetti ME, Doucette J, Claus E, Marottoli R, J Am Geriatr Soc 1995 43 11 1214 1221 7594154
35. [Polypharmacy and psychotropic drugs as risk factors for falls in long-term care setting for elderly patients in Lombardy]. Baranzini F, Poloni N, Diurni M, Ceccon F, Colombo D, Colli C, Ferrari G, Callegari C, Recenti Prog Med 2009 100 1 9 16 19445275
36. Polypharmacy and falls in the middle age and elderly population. Ziere G, Dieleman JP, Hofman A, Pols HA, van der Cammen TJ, Stricker BH, Br J Clin Pharmacol 2006 61 2 218 223 10.1111/j.1365-2125.2005.02543.x 16433876
37. Inappropriate drug use in the elderly: a nationwide register-based study. Johnell K, Fastbom J, Rosen M, Leimanis A, Ann Pharmacother 2007 41 7 1243 1248 10.1345/aph.1K154 17595305
38. Predisposing and precipitating factors for falls among older people in residential care. Kallin K, Lundin-Olsson L, Jensen J, Nyberg L, Gustafson Y, Public Health 2002 116 5 263 271 10.1038/sj.ph.1900849 12209401
39. Risk factors for falls with severe fracture in elderly people living in a middle-income country: a case control study. Coutinho ES, Fletcher A, Bloch KV, Rodrigues LC, BMC Geriatr 2008 8 21 10.1186/1471-2318-8-21 18727832
40. Association between multi-dose drug dispensing and quality of drug treatment-a register-based study. Sjoberg C, Edward C, Fastbom J, Johnell K, Landahl S, Narbro K, Wallerstedt SM, PLoS One 2011 6 10 26574 10.1371/journal.pone.0026574 22066000