Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Velho, Sérgia ^a   Pinto, Ana ^a,b   Licastro, Danilo ^c   Oliveira, Maria J ^b   Sousa, Filipa ^a   Stupka, Elia ^d   Seruca, Raquel ^a,e  

^a UNIVERSITY OF PORTO   (Portugal)

^b INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

^c CBM scrl Area Science Park Basovizza   (Italy)

^d SAN RAFFAELE HOSPITAL   (Italy)

^e University of Porto   (Portugal)

Author keywords

Colorectal cancer; MLK3; MSI; Planar cell polarity; WNT pathway

Indexed keywords

COMPLEMENTARY DNA; DISHEVELLED 2; LYMPHOID ENHANCER FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; MIXED LINEAGE KINASE 3; MYC PROTEIN; NOTCH RECEPTOR; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN; CYCLIN D1; DKK PROTEIN; GLYCOPROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL POLARITY; CELL STRAIN HEK293; COLORECTAL CANCER; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; FZD10 GENE; FZD6 GENE; GENE; GENE MUTATION; GENE VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MLK3 GENE; MUTANT; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE; COLON CARCINOGENESIS; DISEASE ASSOCIATION; GENE FUNCTION; GENETIC ASSOCIATION; PROTEIN TARGETING;

CELL LINE, TUMOR; COLORECTAL NEOPLASMS; GENOME-WIDE ASSOCIATION STUDY; HEK293 CELLS; HUMANS; MAP KINASE KINASE KINASES; MUTAGENESIS, SITE-DIRECTED; SIGNAL TRANSDUCTION;

EID: 84899084890     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-182     Document Type: Article

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