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Volumn 24, Issue 9, 2014, Pages 2163-2167
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A novel Lipoprotein lipase (LPL) agonist rescues the enzyme from inhibition by angiopoietin-like 4 (ANGPTL4)
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Author keywords
ANGPTL4; Atherosclerosis; High throughput screen; Homology model; Ibrolipim; LPL; NO 1886
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Indexed keywords
ANGIOPOIETIN;
ANGIOPOIETIN LIKE 4;
ANTILIPEMIC AGENT;
IBROLIPIM;
LIPOPROTEIN LIPASE;
LIPOPROTEIN LIPASE AGONIST;
UNCLASSIFIED DRUG;
LIPOPROTEIN LIPASE ACTIVATOR;
4-DIETHOXYPHOSPHORYLMETHYL-N-(4-BROMO-2-CYANOPHENYL)BENZAMIDE;
ANGPTL4 PROTEIN, HUMAN;
BENZAMIDE DERIVATIVE;
ORGANOPHOSPHORUS COMPOUND;
ARTICLE;
DRUG DETERMINATION;
DRUG POTENCY;
DRUG RECEPTOR BINDING;
DRUG SCREENING;
ENZYME ACTIVITY;
ENZYME INHIBITION;
IN VITRO STUDY;
MOLECULAR DOCKING;
STRUCTURE ACTIVITY RELATION;
CONTROLLED STUDY;
CRYSTAL STRUCTURE;
ENZYME ACTIVATION;
HYDROGEN BOND;
PROTEIN PROTEIN INTERACTION;
DRUG DEVELOPMENT;
DRUG EFFECTS;
HUMAN;
METABOLISM;
ANGIOPOIETINS;
BENZAMIDES;
DRUG DISCOVERY;
ENZYME ACTIVATION;
HUMANS;
LIPOPROTEIN LIPASE;
MOLECULAR DOCKING SIMULATION;
ORGANOPHOSPHORUS COMPOUNDS;
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EID: 84899072666
PISSN: 0960894X
EISSN: 14643405
Source Type: Journal
DOI: 10.1016/j.bmcl.2014.03.021 Document Type: Article |
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Times cited : (19)
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References (14)
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