Quantitative estimation of insulin sensitivity in type 1 diabetic subjects wearing a sensor-augmented insulin pump

Diabetes Care

Volumn 37, Issue 5, 2014, Pages 1216-1223

  Schiavon, Michele ^a   Dalla Man, Chiara ^a   Kudva, Yogish C ^b   Basu, Ananda ^b   Cobelli, Claudio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL;

ADULT; ARTICLE; BLOOD GLUCOSE MONITORING; CIRCADIAN RHYTHM; CLINICAL ARTICLE; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE SENSOR; HUMAN; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN PUMP; INSULIN SENSITIVITY; INSULIN TREATMENT; MALE; BLOOD; COMPARATIVE STUDY; DIABETES MELLITUS, TYPE 1; INSULIN INFUSION; INSULIN RESISTANCE; MATHEMATICS; MEAL; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; REPRODUCIBILITY; TIME; TREATMENT OUTCOME;

ADULT; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN INFUSION SYSTEMS; INSULIN RESISTANCE; MALE; MATHEMATICS; MEALS; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84899052258     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc13-1120     Document Type: Article

References (24)

1. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979;237:E214-E223 (Pubitemid 9249478)
2. Bergman RN, Ider YZ, Bowden CR, Cobelli C. Quantitative estimation of insulin sensitivity. Am J Physiol 1979;236:E667-E677 (Pubitemid 9220487)
3. Dalla Man C, Caumo A, Basu R, Rizza R, Toffolo G, Cobelli C. Minimal model estimation of glucose absorption and insulin sensitivity from oral test: validation with a tracer method. Am J Physiol Endocrinol Metab 2004;287:E637-E643 (Pubitemid 39237891)
4. Dalla Man C, Yarasheski KE, Caumo A, et al. Insulin sensitivity by oral glucose minimal models: validation against clamp. Am J Physiol Endocrinol Metab 2005;289:E954-E959 (Pubitemid 43671043)
5. Caumo A, Bergman RN, Cobelli C. Insulin sensitivity from meal tolerance tests in normal subjects: a minimal model index. J Clin Endocrinol Metab 2000;85:4396-4402 (Pubitemid 32055404)
6. Stumvoll M, Mitrakou A, Pimenta W, et al. Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity. Diabetes Care 2000;23:295-301 (Pubitemid 30131733)
7. Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22:1462-1470 (Pubitemid 29418240)
8. Hansen T, Drivsholm T, Urhammer SA, et al. The BIGTT test: a novel test for simultaneous measurement of pancreatic β-cell function, insulin sensitivity, and glucose tolerance. Diabetes Care 2007;30:257-262 (Pubitemid 46201651)
9. Breton MD, Kovatchev BP. Method, system and computer program product for evaluation of insulin sensitivity, insulin/carbohydrate ratio, and insulin correction factors in diabetes from self-monitoring data. PCT international patent application PCT/US2008/069416. 8 July 2008
10. Hinshaw L, Dalla Man C, Nandy DK, et al. Diurnal pattern of insulin action in type 1 diabetes: implications for a closed-loop system. Diabetes 2013;62:2223-2229
11. Leelarathna L, Nodale M, Allen JM, et al. Evaluating the accuracy and large inaccuracy of two continuous glucose monitoring systems. Diabetes Technol Ther 2013;15:143-149
12. Basu A, Dalla Man C, Basu R, Toffolo G, Cobelli C, Rizza RA. Effects of type 2 diabetes on insulin secretion, insulin action, glucose effectiveness, and postprandial glucose metabolism. Diabetes Care 2009;32:866-872
13. Guerra S, Facchinetti A, Sparacino G, Nicolao GD, Cobelli C. Enhancing the accuracy of subcutaneous glucose sensors: a real-time deconvolution-based approach. IEEE Trans Biomed Eng 2012;59:1658-1669
14. Del Favero S, Facchinetti A, Sparacino G, Cobelli C. Retrofitting algorithm: fusing CGM and references to reconstruct a reliable continuous glucose profile. Paris, Advanced Technologies and Treatments for Diabetes, 2013
15. Toffolo GM, Campioni M, Basu R, Rizza RA, Cobelli C. A minimal model of insulin secretion and kinetics to assess hepatic insulin extraction. Am J Physiol Endocrinol Metab 2006;290:E169-E176
16. Campioni M, Toffolo G, Basu R, Rizza RA, Cobelli C. Minimal model assessment of hepatic insulin extraction during an oral test from standard insulin kinetic parameters. Am J Physiol Endocrinol Metab 2009;297:E941-E948
17. Patek SD, Magni L, Dassau E, et al.; International Artificial Pancreas (iAP) Study Group. Modular closed-loop control of diabetes. IEEE Trans Biomed Eng 2012;59:2986-2999
18. Ellingsen C, Dassau E, Zisser H, et al. Safety constraints in an artificial pancreatic beta cell: an implementation of model predictive control with insulin on board. J Diabetes Sci Tech 2009;3:536-544
19. Dalla Man C, Camilleri M, Cobelli C. A system model of oral glucose absorption: validation on gold standard data. IEEE Trans Biomed Eng 2006;53:2472-2478 (Pubitemid 46019534)
20. Cobelli C, Dalla Man C, Schiavon M, Basu A, Kudva Y. Estimation of insulin sensitivity from CGM and subcutaneous insulin delivery in type 1 diabetes. U.S. patent application US 13/661,755. 26 October 2012
21. Kovatchev BP, Breton M, Man CD, Cobelli C. In silico preclinical trials: a proof of concept in closed-loop control of type 1 diabetes. J Diabetes Sci Tech 2009;3:44-55
22. Davis SN, Horton ES, Battelino T, Rubin RR, Schulman KA, Tamborlane WV. STAR 3 randomized controlled trial to compare sensor-augmented insulin pump therapy with multiple daily injections in the treatment of type 1 diabetes: research design, methods, and baseline characteristics of enrolled subjects. Diabetes Technol Ther 2010;12:249-255
23. Yodfat O, Shapira G, Gescheit I. A method system and device for assessing insulin sensitivity. PCT publication US20080319381. 31 December 2008
24. Bevier WC, Zisser H, Palerm CC, et al. Calculating the insulin to carbohydrate ratio using the hyperinsulinaemiceuglycaemic clamp-a novel use for a proven technique. Diabetes Metab Res Rev 2007;23:472-478 (Pubitemid 47520904)