메뉴 건너뛰기




Volumn 146, Issue 5, 2014, Pages 1397-1407

Activating mutations in PTPN3 promote cholangiocarcinoma cell proliferation and migration and are associated with tumor recurrence in patients

Author keywords

Carcinogenesis; Keywords; Liver Cancer; Phosphorylation; Signal Transduction

Indexed keywords

NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 3; PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE;

EID: 84899032205     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.01.062     Document Type: Article
Times cited : (111)

References (37)
  • 2
    • 84888250929 scopus 로고    scopus 로고
    • Pathogenesis, diagnosis, and management of cholangiocarcinoma
    • S. Rizvi, and G.J. Gores Pathogenesis, diagnosis, and management of cholangiocarcinoma Gastroenterology 145 2013 1215 1229
    • (2013) Gastroenterology , vol.145 , pp. 1215-1229
    • Rizvi, S.1    Gores, G.J.2
  • 3
    • 84875237481 scopus 로고    scopus 로고
    • Intrahepatic cholangiocarcinoma: Pathogenesis and rationale for molecular therapies
    • D. Sia, V. Tovar, and A. Moeini et al. Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies Oncogene 32 2013 4861 4870
    • (2013) Oncogene , vol.32 , pp. 4861-4870
    • Sia, D.1    Tovar, V.2    Moeini, A.3
  • 4
    • 79251469043 scopus 로고    scopus 로고
    • Development of molecularly targeted therapies in biliary tract cancers: Reassessing the challenges and opportunities
    • A.X. Zhu, and A.F. Hezel Development of molecularly targeted therapies in biliary tract cancers: reassessing the challenges and opportunities Hepatology 53 2011 695 704
    • (2011) Hepatology , vol.53 , pp. 695-704
    • Zhu, A.X.1    Hezel, A.F.2
  • 5
    • 84861581233 scopus 로고    scopus 로고
    • Exome sequencing of liver fluke-associated cholangiocarcinoma
    • C.K. Ong, C. Subimerb, and C. Pairojkul et al. Exome sequencing of liver fluke-associated cholangiocarcinoma Nat Genet 44 2012 690 693
    • (2012) Nat Genet , vol.44 , pp. 690-693
    • Ong, C.K.1    Subimerb, C.2    Pairojkul, C.3
  • 6
    • 84888385562 scopus 로고    scopus 로고
    • Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers
    • W. Chan-On, M.L. Nairismagi, and C.K. Ong et al. Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers Nat Genet 45 2013 1474 1478
    • (2013) Nat Genet , vol.45 , pp. 1474-1478
    • Chan-On, W.1    Nairismagi, M.L.2    Ong, C.K.3
  • 7
    • 84888353882 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas
    • Y. Jiao, T.M. Pawlik, and R.A. Anders et al. Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas Nat Genet 45 2013 1470 1473
    • (2013) Nat Genet , vol.45 , pp. 1470-1473
    • Jiao, Y.1    Pawlik, T.M.2    Anders, R.A.3
  • 8
    • 79959572626 scopus 로고    scopus 로고
    • Risk factors for cholangiocarcinoma
    • G.L. Tyson, and H.B. El-Serag Risk factors for cholangiocarcinoma Hepatology 54 2011 173 184
    • (2011) Hepatology , vol.54 , pp. 173-184
    • Tyson, G.L.1    El-Serag, H.B.2
  • 9
    • 84864966749 scopus 로고    scopus 로고
    • Intratumoral IL-17(+) cells and neutrophils show strong prognostic significance in intrahepatic cholangiocarcinoma
    • F.M. Gu, Q. Gao, and G.M. Shi et al. Intratumoral IL-17(+) cells and neutrophils show strong prognostic significance in intrahepatic cholangiocarcinoma Ann Surg Oncol 19 2012 2506 2514
    • (2012) Ann Surg Oncol , vol.19 , pp. 2506-2514
    • Gu, F.M.1    Gao, Q.2    Shi, G.M.3
  • 10
    • 84868320535 scopus 로고    scopus 로고
    • Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer
    • H. Liang, L.W. Cheung, and J. Li et al. Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer Genome Res 22 2012 2120 2129
    • (2012) Genome Res , vol.22 , pp. 2120-2129
    • Liang, H.1    Cheung, L.W.2    Li, J.3
  • 11
    • 82255183148 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
    • K. Wang, J. Kan, and S.T. Yuen et al. Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer Nat Genet 43 2011 1219 1223
    • (2011) Nat Genet , vol.43 , pp. 1219-1223
    • Wang, K.1    Kan, J.2    Yuen, S.T.3
  • 12
    • 84861625981 scopus 로고    scopus 로고
    • Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
    • C. Guichard, G. Amaddeo, and S. Imbeaud et al. Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma Nat Genet 44 2012 694 698
    • (2012) Nat Genet , vol.44 , pp. 694-698
    • Guichard, C.1    Amaddeo, G.2    Imbeaud, S.3
  • 13
    • 33947101019 scopus 로고    scopus 로고
    • Patterns of somatic mutation in human cancer genomes
    • C. Greenman, P. Stephens, and R. Smith et al. Patterns of somatic mutation in human cancer genomes Nature 446 2007 153 158
    • (2007) Nature , vol.446 , pp. 153-158
    • Greenman, C.1    Stephens, P.2    Smith, R.3
  • 14
    • 80052269038 scopus 로고    scopus 로고
    • Analysis of the coding genome of diffuse large B-cell lymphoma
    • L. Pasqualucci, V. Trifonov, and G. Fabbri et al. Analysis of the coding genome of diffuse large B-cell lymphoma Nat Genet 43 2011 830 837
    • (2011) Nat Genet , vol.43 , pp. 830-837
    • Pasqualucci, L.1    Trifonov, V.2    Fabbri, G.3
  • 15
    • 84866868120 scopus 로고    scopus 로고
    • Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma
    • J. Huang, Q. Deng, and Q. Wang et al. Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma Nat Genet 44 2012 1117 1121
    • (2012) Nat Genet , vol.44 , pp. 1117-1121
    • Huang, J.1    Deng, Q.2    Wang, Q.3
  • 16
    • 78651330430 scopus 로고    scopus 로고
    • COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
    • S.A. Forbes, N. Bindal, and S. Bamford et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer Nucleic Acids Res 39 2011 D945 D950
    • (2011) Nucleic Acids Res , vol.39
    • Forbes, S.A.1    Bindal, N.2    Bamford, S.3
  • 17
    • 84870011791 scopus 로고    scopus 로고
    • Loss of receptor protein tyrosine phosphatase beta/zeta (RPTPbeta/zeta) promotes prostate cancer metastasis
    • Z. Diamantopoulou, P. Kitsou, and S. Menashi et al. Loss of receptor protein tyrosine phosphatase beta/zeta (RPTPbeta/zeta) promotes prostate cancer metastasis J Biol Chem 287 2012 40339 40349
    • (2012) J Biol Chem , vol.287 , pp. 40339-40349
    • Diamantopoulou, Z.1    Kitsou, P.2    Menashi, S.3
  • 18
    • 84869854258 scopus 로고    scopus 로고
    • Function and cancer genomics of FAT family genes (Review)
    • M. Katoh Function and cancer genomics of FAT family genes (Review) Int J Oncol 41 2012 1913 1918
    • (2012) Int J Oncol , vol.41 , pp. 1913-1918
    • Katoh, M.1
  • 19
    • 75949130596 scopus 로고    scopus 로고
    • Mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in carcinogenesis
    • I. Martin-Kleiner, and K. Gall Troselj Mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in carcinogenesis Cancer Lett 289 2010 11 22
    • (2010) Cancer Lett , vol.289 , pp. 11-22
    • Martin-Kleiner, I.1    Gall Troselj, K.2
  • 20
    • 0036119504 scopus 로고    scopus 로고
    • Accounting for human polymorphisms predicted to affect protein function
    • P.C. Ng, and S. Henikoff Accounting for human polymorphisms predicted to affect protein function Genome Res 12 2002 436 446
    • (2002) Genome Res , vol.12 , pp. 436-446
    • Ng, P.C.1    Henikoff, S.2
  • 21
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • W. Huang da, B.T. Sherman, and R.A. Lempicki Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat Protoc 4 2009 44 57
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 22
    • 78650601353 scopus 로고    scopus 로고
    • Inside the human cancer tyrosine phosphatome
    • S.G. Julien, N. Dube, and S. Hardy et al. Inside the human cancer tyrosine phosphatome Nat Rev Cancer 11 2011 35 49
    • (2011) Nat Rev Cancer , vol.11 , pp. 35-49
    • Julien, S.G.1    Dube, N.2    Hardy, S.3
  • 24
    • 77951640946 scopus 로고    scopus 로고
    • A method and server for predicting damaging missense mutations
    • I.A. Adzhubei, S. Schmidt, and L. Peshkin et al. A method and server for predicting damaging missense mutations Nat Methods 7 2010 248 249
    • (2010) Nat Methods , vol.7 , pp. 248-249
    • Adzhubei, I.A.1    Schmidt, S.2    Peshkin, L.3
  • 25
    • 77950794747 scopus 로고    scopus 로고
    • PTPH1 dephosphorylates and cooperates with p38gamma MAPK to increase ras oncogenesis through PDZ-mediated interaction
    • S.W. Hou, H.Y. Zhi, and N. Pohl et al. PTPH1 dephosphorylates and cooperates with p38gamma MAPK to increase ras oncogenesis through PDZ-mediated interaction Cancer Res 70 2010 2901 2910
    • (2010) Cancer Res , vol.70 , pp. 2901-2910
    • Hou, S.W.1    Zhi, H.Y.2    Pohl, N.3
  • 26
    • 79953789899 scopus 로고    scopus 로고
    • PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization
    • H.Y. Zhi, S.W. Hou, and R.S. Li et al. PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization Oncogene 30 2011 1706 1715
    • (2011) Oncogene , vol.30 , pp. 1706-1715
    • Zhi, H.Y.1    Hou, S.W.2    Li, R.S.3
  • 27
    • 84865009345 scopus 로고    scopus 로고
    • P38gamma Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response
    • S. Hou, P.S. Suresh, and X. Qi et al. p38gamma Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response J Biol Chem 287 2012 27895 27905
    • (2012) J Biol Chem , vol.287 , pp. 27895-27905
    • Hou, S.1    Suresh, P.S.2    Qi, X.3
  • 28
    • 0037044786 scopus 로고    scopus 로고
    • Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1
    • Y. Zheng, J. Schlondorff, and C.P. Blobel Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1 J Biol Chem 277 2002 42463 42470
    • (2002) J Biol Chem , vol.277 , pp. 42463-42470
    • Zheng, Y.1    Schlondorff, J.2    Blobel, C.P.3
  • 29
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • Cancer Genome Atlas Network
    • Cancer Genome Atlas Network Comprehensive molecular characterization of human colon and rectal cancer Nature 487 2012 330 337
    • (2012) Nature , vol.487 , pp. 330-337
  • 30
    • 2442648882 scopus 로고    scopus 로고
    • Mutational analysis of the tyrosine phosphatome in colorectal cancers
    • Z. Wang, D. Shen, and D.W. Parsons et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers Science 304 2004 1164 1166
    • (2004) Science , vol.304 , pp. 1164-1166
    • Wang, Z.1    Shen, D.2    Parsons, D.W.3
  • 31
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network Integrated genomic analyses of ovarian carcinoma Nature 474 2011 609 615
    • (2011) Nature , vol.474 , pp. 609-615
  • 32
    • 84856268319 scopus 로고    scopus 로고
    • Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
    • S.I. Nikolaev, D. Rimoldi, and C. Iseli et al. Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma Nat Genet 44 2011 133 139
    • (2011) Nat Genet , vol.44 , pp. 133-139
    • Nikolaev, S.I.1    Rimoldi, D.2    Iseli, C.3
  • 33
    • 84875244110 scopus 로고    scopus 로고
    • Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes
    • D. Sia, Y. Hoshida, and A. Villanueva et al. Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes Gastroenterology 144 2013 829 840
    • (2013) Gastroenterology , vol.144 , pp. 829-840
    • Sia, D.1    Hoshida, Y.2    Villanueva, A.3
  • 34
    • 84859441690 scopus 로고    scopus 로고
    • Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors
    • J.B. Andersen, B. Spee, and B.R. Blechacz et al. Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors Gastroenterology 142 2012 1021 1031.e15
    • (2012) Gastroenterology , vol.142
    • Andersen, J.B.1    Spee, B.2    Blechacz, B.R.3
  • 35
    • 79955528598 scopus 로고    scopus 로고
    • Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function
    • Y. Xu, W. Xia, and D. Baker et al. Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function J Biol Chem 286 2011 15980 15988
    • (2011) J Biol Chem , vol.286 , pp. 15980-15988
    • Xu, Y.1    Xia, W.2    Baker, D.3
  • 36
    • 82755168803 scopus 로고    scopus 로고
    • Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers
    • L.G. Morris, B.S. Taylor, and T.G. Bivona et al. Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers Proc Natl Acad Sci U S A 108 2011 19024 19029
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 19024-19029
    • Morris, L.G.1    Taylor, B.S.2    Bivona, T.G.3
  • 37
    • 84880901185 scopus 로고    scopus 로고
    • EYA1 phosphatase function is essential to drive breast cancer cell proliferation through cyclin D1
    • K. Wu, Z. Li, and S. Cai et al. EYA1 phosphatase function is essential to drive breast cancer cell proliferation through cyclin D1 Cancer Res 73 2013 4488 4499
    • (2013) Cancer Res , vol.73 , pp. 4488-4499
    • Wu, K.1    Li, Z.2    Cai, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.