Spatial memory impairments in amnestic mild cognitive impairment in a virtual radial arm maze

Neuropsychiatric Disease and Treatment

Volumn 10, Issue , 2014, Pages 653-660

  Lee, Jun Young ^a,b   Kho, Sooyeon ^a,b   Yoo, Hye Bin ^a,b   Park, Soowon ^a,b   Choi, Jung Seok ^a,b   Kwon, Jun Soo ^c   Cha, Kyung Ryeol ^d   Jung, Hee Yeon ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University Boramae Hospital   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

^d Osan Mental Health Center   (South Korea)

Author keywords

Alzheimer's disease; Cognition; Spatial behavior; User computer interface

Indexed keywords

AGED; ALZHEIMER DISEASE; AMNESIA; ARTICLE; CLINICAL ARTICLE; CLINICAL DEMENTIA RATING; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; NEUROPSYCHOLOGICAL TEST; RADIAL ARM MAZE TEST; REFERENCE MEMORY; SPATIAL MEMORY; VIRTUAL REALITY;

EID: 84899024454     PISSN: 11766328     EISSN: 11782021     Source Type: Journal    
DOI: 10.2147/ndt.s58185     Document Type: Article

References (44)

1. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999;56(3):303-308.
2. Pennanen C, Kivipelto M, Tuomainen S, et al. Hippocampus and ento-rhinal cortex in mild cognitive impairment and early AD. Neurobiol Aging. 2004;25(3):303-310.
3. Mosconi L, Tsui WH, De Santi S, et al. Reduced hippocampal metabolism in MCI and AD Automated FDG-PET image analysis. Neurology. 2005;64(11):1860-1867.
4. Korf ES, Wahlund LO, Visser PJ, Scheltens P. Medial temporal lobe atrophy on MRI predicts dementia in patients with mild cognitive impairment. Neurology. 2004;63(1):94-100.
5. Maguire EA, Burgess N, Donnett JG, Frackowiak RS, Frith CD, O'Keefe J. Knowing where and getting there: a human navigation network. Science. 1998;280(5365):921-924.
6. Pai MC, Jacobs WJ. Topographical disorientation in community-residing patients with Alzheimer's disease. Int J Geriatr Psychiatry. 2004;19(3):250-255.
7. Hort J, Laczo J, Vyhnalek M, Bojar M, Bures J, Vlcek K. Spatial navigation defcit in amnestic mild cognitive impairment. Proc Natl Acad Sci U S A. 2007;104(10):4042-4047.
8. Alescio-Lautier B, Michel BF, Herrera C, et al. Visual and visuospatial short-term memory in mild cognitive impairment and Alzheimer disease: role of attention. Neuropsychologia. 2007;45(8):1948-1960.
9. Plancher G, Tirard A, Gyselinck V, Nicolas S, Piolino P. Using virtual reality to characterize episodic memory profles in amnestic mild cognitive impairment and Alzheimer's disease: Infuence of active and passive encoding. Neuropsychologia. 2012;50(5):592-602.
10. Cushman LA, Stein K, Duffy CJ. Detecting navigational defcits in cognitive aging and Alzheimer disease using virtual reality. Neurology. 2008;71(12):888-895.
11. Tippett WJ, Lee JH, Zakzanis KK, Black SE, Mraz R, Graham SJ. Visually navigating a virtual world with real-world impairments: a study of visually and spatially guided performance in individuals with mild cognitive impairments. J Clin Exp Neuropsychol. 2009;31(4): 447-454.
12. Spieker EA, Astur RS, West JT, Griego JA, Rowland LM. Spatial memory defcits in a virtual reality eight-arm radial maze in schizophrenia. Schizophrenia Res. 2012;135(1-3):84-89.
13. Zakzanis KK, Quintin G, Graham SJ, Mraz R. Age and dementia related differences in spatial navigation within an immersive virtual environment. Med Sci Monit. 2009;15(4):CR140-CR150.
14. Bellassen V, Iglói K, de Souza LC, Dubois B, Rondi-Reig L. Temporal order memory assessed during spatiotemporal navigation as a behavioral cognitive marker for differential Alzheimer's disease diagnosis. J Neurosci. 2012;32(6):1942-1952.
15. Moffat SD, Zonderman AB, Resnick SM. Age differences in spatial memory in a virtual environment navigation task. Neurobiol Aging. 2001;22(5):787-796.
16. Astur RS, Taylor LB, Mamelak AN, Philpott L, Sutherland RJ. Humans with hippocampus damage display severe spatial memory impairments in a virtual Morris water task. Behav Brain Res. 2002; 132(1):77-84.
17. Moffat SD, Resnick SM. Effects of age on virtual environment place navigation and allocentric cognitive mapping. Behav Neurosci. 2002;116(5):851-859.
18. Gresack JE, Frick KM. Male mice exhibit better spatial working and reference memory than females in a water-escape radial arm maze task. Brain Res. 2003;982(1):98-107.
19. Levin ED, Kim P, Meray R. Chronic nicotine working and reference memory effects in the 16-arm radial maze: interactions with D1 agonist and antagonist drugs. Psychopharmacology (Berl). 1996;127(1): 25-30.
20. Astur RS, Tropp J, Sava S, Constable RT, Markus EJ. Sex differences and correlations in a virtual Morris water task, a virtual radial arm maze, and mental rotation. Behav Brain Res. 2004;151(1-2): 103-115.
21. Bimonte HA, Nelson ME, Granholm AC. Age-related defcits as working memory load increases: relationships with growth factors. Neurobiol Aging. 2003;24(1):37-48.
22. Astur RS, St Germain SA, Baker EK, Calhoun V, Pearlson GD, Constable RT. fMRI hippocampal activity during a virtual radial arm maze. Appl Psychophysiol Biofeedback. 2005;30(3):307-317.
23. Becker JT, Walker JA, Olton DS. Neuroanatomical bases of spatial memory. Brain Res. 1980;200(2):307-320.
24. Floresco SB, Seamans JK, Phillips AG. Selective roles for hippocampal, prefrontal cortical, and ventral striatal circuits in radial-arm maze tasks with or without a delay. J Neurosci. 1997;17(5):1880-1890.
25. Hasselmo ME. A model of prefrontal cortical mechanisms for goal-directed behavior. J Cogn Neursci. 2005;17(7):1115-1129.
26. Prior H, Schwegler H, Ducker G. Dissociation of spatial reference memory, spatial working memory, and hippocampal mossy fber distribution in two rat strains differing in emotionality. Behav Brain Res. 1997;87(2):183-194.
27. Frick KM, Baxter MG, Markowska AL, Olton DS, Price DL. Age-related spatial reference and working memory defcits assessed in the water maze. Neurobiol Aging. 1995;16(2):149-160.
28. Burgess N, Maguire EA, O'Keefe J. The human hippocampus and spatial and episodic memory. Neuron. 2002;35(4):625-641.
29. Courtney SM, Petit L, Maisog JM, Ungerleider LG, Haxby J V. An area specialized for spatial working memory in human frontal cortex. Science. 1998;279(5355):1347-1351.
30. Courtney SM, Ungerleider LG, Keil K, Haxby J V. Transient and sustained activity in a distributed neural system for human working memory. Nature. 1997;386(6625):608-611.
31. Iachini I, Iavarone A, Senese V P, Ruotolo F, Ruggiero G. Visuospatial memory in healthy elderly, AD and MCI: a review. Curr Aging Sci. 2009;2(1):43-59.
32. deIpolyi AR, Rankin K P, Mucke L, Miller BL, Gorno-Tempini ML. Spatial cognition and the human navigation network in AD and MCI. Neurolog y. 2007;69(10):986-997.
33. Dickerson BC, Bakkour A, Salat DH, et al. The cortical signature of Alzheimer's disease: regionally specifc cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cereb Cortex. 2009;19(3): 497-510.
34. Lesher EL, Berryhill JS. Validation of the Geriatric Depression Scale - Short Form among inpatients. J Clin Psychol. 1994;50(2): 256-260.
35. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34(7):939-944.
36. Morris JC. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology. 1993;43(11):2412-2414.
37. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198.
38. Lee DY, Lee K W, Lee JH, et al. A normative study of Mini-mental state examination in the Korean elderly. J Korean Neuropsychiatr Assoc. 2002;41(3):508-525.
39. Milberg W P, Hebben N, Kaplan E. The Boston Process Approach to Neuropsychological Assessment. In: Grant I, Adams K, editors. Neu-ropsychological Assessment of Neuropsychiatric Disorders. New York: Oxford University Press; 1996:58-80.
40. Rizzo M, Anderson S W, Dawson J, Myers R, Ball K. Visual attention impairments in Alzheimer's disease. Neurology. 2000;54(10): 1954-1959.
41. Backman L, Jones S, Berger AK, Laukka EJ, Small BJ. Cognitive impairment in preclinical Alzheimer's disease: a meta-analysis. Neuropsychology. 2005;19(4):520-531.
42. Gorus E, De Raedt R, Lambert M, Lemper JC, Mets T. Reaction times and performance variability in normal aging, mild cognitive impairment, and Alzheimer's disease. J Geriatr Psychiatry Neurol. 2008;21(3): 204-218.
43. Tales A, Snowden RJ, Haworth J, Wilcock G. Abnormal spatial and non-spatial cueing effects in mild cognitive impairment and Alzheimer's disease. Neurocase. 2005;11(1):85-92.
44. Cornoldi C, Mammarella IC. A comparison of backward and forward spatial spans. Q J Exp Psychol (Hove). 2008;61(5):674-682.