Analysis of 3-O-sulfo group-containing heparin tetrasaccharides in heparin by liquid chromatography-mass spectrometry

Analytical Biochemistry

Volumn 455, Issue 1, 2014, Pages 3-9

  Li, Guoyun ^a,b   Yang, Bo ^b   Li, Lingyun ^b   Zhang, Fuming ^c   Xue, Changhu ^a   Linhardt, Robert J ^b,c,d  

^a OCEAN UNIVERSITY OF CHINA   (China)

^b Research Rensselaer Polytechnic Institute   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^d RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

3 O Sulfo group; Anticoagulant activity; Heparin lyase 2; Porcine intestinal heparin; RPIP LC MS; Tetrasaccharides

Indexed keywords

BINDING SITES; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR WEIGHT;

3-O-SULFO GROUP; ANTICOAGULANT ACTIVITIES; HEPARIN LYASE 2; PORCINE INTESTINAL HEPARIN; RPIP-LC-MS; TETRASACCHARIDES;

POLYSACCHARIDES;

3 O SULFO GROUP CONTAINING HEPARIN TETRASACCHARIDE; ANTITHROMBIN III; DISACCHARIDE; HEPARIN; HEPARIN LYASE; HEPARIN LYASE 2; LOW MOLECULAR WEIGHT HEPARIN; TETRASACCHARIDE; UNCLASSIFIED DRUG; ANTICOAGULANT AGENT;

ANTICOAGULATION; ARTICLE; BINDING SITE; DEPOLYMERIZATION; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; CARBOHYDRATE ANALYSIS; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PIG; PROCEDURES; STANDARDS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTICOAGULANTS; ANTITHROMBIN III; BINDING SITES; CARBOHYDRATE SEQUENCE; CHROMATOGRAPHY, LIQUID; HEPARIN LYASE; HEPARIN, LOW-MOLECULAR-WEIGHT; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 84898947004     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2014.02.033     Document Type: Article

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