Age independently affects myelin integrity as detected by magnetization transfer magnetic resonance imaging in multiple sclerosis

NeuroImage: Clinical

Volumn 4, Issue , 2014, Pages 641-648

  Newbould, R D ^a   Nicholas, R ^a   Thomas, C L ^a   Quest, R ^b   Lee, J S Z ^a   Honeyfield, L ^b   Colasanti, A ^a   Malik, O ^a   Mattoscio, M ^a   Matthews, P M ^a,c   Sormani, M P ^d   Waldman, A D ^a,b   Muraro, P A ^a,b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

Aging; Magnetization transfer; MRI; Multiple sclerosis

Indexed keywords

GADOLINIUM; MYELIN;

ADULT; AGE; ARTICLE; BRAIN INJURY; BRAIN SIZE; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; DISEASE DURATION; EXPANDED DISABILITY STATUS SCALE; FEMALE; GRAY MATTER LESIONS; HUMAN; MALE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM PARAMETERS; NORMAL APPEARING GRAY MATTER; NORMAL APPEARING WHITE MATTER; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SEX DIFFERENCE; AGING; BRAIN; DISABILITY; MIDDLE AGED; MYELIN SHEATH; PATHOLOGY; THREE DIMENSIONAL IMAGING; AGED; AUTOMATION; GRAY MATTER; HISTOGRAM; WHITE MATTER LESION;

ADULT; AGE FACTORS; AGING; BRAIN; DISABILITY EVALUATION; FEMALE; HUMANS; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; MYELIN SHEATH; ROC CURVE;

EID: 84898945367     PISSN: None     EISSN: 22131582     Source Type: Journal    
DOI: 10.1016/j.nicl.2014.02.004     Document Type: Article

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