Mannose supplements induce embryonic lethality and blindness in phosphomannose isomerase hypomorphic mice

FASEB Journal

Volumn 28, Issue 4, 2014, Pages 1854-1869

  Sharma, Vandana ^a   Nayak, Jonamani ^a   DeRossi, Charles ^a,c   Charbono, Adriana ^a   Ichikawa, Mie ^a   Ng, Bobby G ^a   Grajales Esquivel, Erika ^b   Srivastava, Anand ^a,d   Wang, Ling ^a   He, Ping ^a   Scott, David A ^a   Russell, Joseph ^a,e   Contreras, Emily ^a,f   Guess, Cherise M ^a,g   Krajewski, Stan ^a   Del Rio Tsonis, Katia ^b   Freeze, Hudson H ^a  

^a BURNHAM INSTITUTE   (United States)

^b MIAMI UNIVERSITY   (United States)

^c Center for Metabolic Diseases Heidelberg   (Germany)

^d Global Institute of Stem Cell Therapy and Research   (United States)

^e JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^f Riley Children's Specialists   (United States)

^g ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Congenital disorder of glycosylation; Eye defects; Lens; MPI CDG

Indexed keywords

DRINKING WATER; MANNOSE; MANNOSE PHOSPHATE ISOMERASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLINDNESS; CONTROLLED STUDY; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; EYE DEVELOPMENT; EYE MALFORMATION; FEMALE; FIBROBLAST; LITTER SIZE; METABOLITE; MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; SUPPLEMENTATION; SURVIVAL; SURVIVOR; WEANING;

CONGENITAL DISORDER OF GLYCOSYLATION; EYE DEFECTS; LENS; MPI-CDG;

ANIMALS; BLINDNESS; BLOTTING, WESTERN; CELLS, CULTURED; CONGENITAL DISORDERS OF GLYCOSYLATION; DIETARY SUPPLEMENTS; EMBRYO, MAMMALIAN; EYE; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MANNOSE; MANNOSE-6-PHOSPHATE ISOMERASE; MANNOSEPHOSPHATES; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PLACENTA; PREGNANCY;

EID: 84898940011     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-245514     Document Type: Article

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