New steroids with a rearranged skeleton as (h)P300 inhibitors from the sponge theonella swinhoei

Organic Letters

Volumn 16, Issue 8, 2014, Pages 2224-2227

  Gong, Jun ^a   Sun, Peng ^a   Jiang, Nan ^b   Riccio, Raffaele ^c   Lauro, Gianluigi ^c   Bifulco, Giuseppe ^c   Li, Tie Jun ^a   Gerwick, William H ^d   Zhang, Wen ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF SALERNO   (Italy)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

E1A ASSOCIATED P300 PROTEIN; EP300 PROTEIN, HUMAN; STEROID; SWINHOEISTEROL A; SWINHOEISTEROL B;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; DRUG SCREENING; HUMAN; ISOLATION AND PURIFICATION; MARINE BIOLOGY; THEONELLA; X RAY CRYSTALLOGRAPHY;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; E1A-ASSOCIATED P300 PROTEIN; HUMANS; MARINE BIOLOGY; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; STEROIDS; THEONELLA;

EID: 84898931634     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol5007345     Document Type: Article

References (24)

1. DAuria, M. V.; Minale, L.; Riccio, R. Chem. Rev. 1993, 93, 1839-1895
2. Kerr, R. G.; Baker, B. J. Nat. Prod. Rep. 1991, 8, 465-497
3. Aiello, A.; Fattorusso, E.; Menna, M. Steroids 1999, 64, 687-714
4. Sica, D.; Musumeci, D. Steroids 2004, 69, 743-756
5. Sun, P.; Xu, D.-X.; Mándi, A.; Kurtán, T.; Li, T.-J.; Schulz, B.; Zhang, W. J. Org. Chem. 2013, 78, 7030-7047
6. Sun, P.; Meng, L.-Y.; Tang, H.; Liu, B.-S.; Li, L.; Yi, Y.; Zhang, W. J. Nat. Prod. 2012, 75, 1656-1659
7. Geng, W.-L.; Wang, X.-Y.; Kurtán, T.; Mándi, A.; Tang, H.; Schulz, B.; Sun, P.; Zhang, W. J. Nat. Prod. 2012, 75, 1828-1832
8. Jiang, M.; Sun, P.; Tang, H.; Liu, B.-S.; Li, T.-J.; Li, C.; Zhang, W. J. Nat. Prod. 2013, 76, 764-768
9. Sinisi, A.; Calcinai, B.; Cerrano, C.; Dien, H. A.; Zampella, A.; DAmore, C.; Renga, B.; Fiorucci, S.; Taglialatela-Scafati, O. Bioorg. Med. Chem. 2013, 21, 5332-5338
10. De Marino, S.; Ummarino, R.; DAuria, M. V.; Chini, M. G.; Bifulco, G.; Renga, B.; DAmore, C.; Fiorucci, S.; Debitus, C.; Zampella, A. J. Med. Chem. 2011, 54, 3065-3075
11. Guo, J.-K.; Chiang, C.-Y.; Lu, M.-C.; Chang, W.-B.; Su, J.-H. Mar. Drugs 2012, 10, 1536-1544 and references cited therein
12. Kho, E.; Imagawa, D. K.; Rohmer, M.; Kashman, Y.; Djerassi, C. J. Org. Chem. 1981, 46, 1836-1839
13. Sugo, Y.; Inouye, Y.; Nakayama, N. Steroids 1995, 60, 738-742
14. Umeyama, A.; Shoji, N.; Enoki, M.; Arihara, S. J. Nat. Prod. 1997, 60, 296-298
15. Seco, J. M.; Quiñoá, E.; Riguera, R. Chem. Rev. 2004, 104, 17-118
16. Sright, J. L. C.; McInnes, A. G.; Shimizu, S.; Smith, D. G.; Walter, J. A.; Idler, D.; Khalil, W. Can. J. Chem. 1978, 56, 1898-1903
17. Demarco, P. V.; Farkas, E.; Doddrell, D.; Mylari, B. L.; Wenkert, E. J. Am. Chem. Soc. 1968, 90, 5480-5486
18. Flack, H. D. Acta Crystallogr. 1983, A39, 876-881
19. Cheruku, P.; Plaza, A.; Lauro, G.; Keffer, J.; Lloyd, J. R.; Bifulco, G.; Bewley, C. A. J. Med. Chem. 2012, 55, 735-742
20. Lauro, G.; Romano, A.; Riccio, R.; Bifulco, G. J.Nat. Prod. 2011, 74, 1401-1407
21. Berger, S. L. Curr. Opin. Genet. Dev. 2002, 12, 142-148
22. Goodman, R. H.; Smolik, S. Gene Dev. 2000, 14, 1553-1577
23. Zheng, Y.; Balasubramanyam, K.; Cebrat, M.; Buck, D.; Guidez, F.; Zelent, A.; Alani, R. M.; Cole, P. A. J. Am. Chem. Soc. 2005, 127, 17182-17183
24. Dekker, F. J.; Haisma, H. J. Drug Discovery Today 2009, 14, 942-948