Edaravone protects endotoxin-induced liver injury by inhibiting apoptosis and reducing proinflammatory cytokines

Brazilian Journal of Medical and Biological Research

Volumn 47, Issue 3, 2014, Pages 231-236

  Zong, L ^a,b   Yu, Q H ^a   Du, Y X ^b   Deng, X M ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b Department of Anesthesiology ^*  (China)

Author keywords

Apoptosis; Daravone; Endotoxin; Inflammation; Liver injury

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 8; CYTOKINE; INTERLEUKIN 6; NORPHENAZONE; TUMOR NECROSIS FACTOR ALPHA; ENDOTOXIN; GALACTOSAMINE; LIPOPOLYSACCHARIDE; PHENAZONE; PHENYLMETHYLPYRAZOLONE; SCAVENGER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; MORTALITY; MOUSE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; SCORING SYSTEM; SURVIVAL RATE; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; BLOOD; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; LIVER CELL; METABOLISM; PATHOPHYSIOLOGY; RANDOMIZATION; TOXICITY;

ALANINE TRANSAMINASE; ANIMALS; ANTIPYRINE; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; CASPASE 3; CASPASE 8; CYTOKINES; DRUG-INDUCED LIVER INJURY; ENDOTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FREE RADICAL SCAVENGERS; GALACTOSAMINE; HEPATOCYTES; IN SITU NICK-END LABELING; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MICE, INBRED BALB C; RANDOM ALLOCATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84898897138     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/1414-431X20133186     Document Type: Article

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