메뉴 건너뛰기




Volumn 35, Issue 2, 2014, Pages 1551-1556

Inhibition of focal adhesion kinase induces apoptosis in human osteosarcoma SAOS-2 cells

Author keywords

Apoptosis; Focal adhesion kinase; Human osteosarcoma cells; SAOS 2 cells

Indexed keywords

BETA ACTIN; CASPASE 3; CASPASE 7; CASPASE 9; CISPLATIN; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SHORT HAIRPIN RNA; SHRNA 334; UNCLASSIFIED DRUG;

EID: 84898850082     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-1214-0     Document Type: Article
Times cited : (14)

References (26)
  • 1
    • 0026497659 scopus 로고
    • Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets
    • Lipfert L, Haimovich B, Schaller MD, Cobb BS, Parsons JT, Brugge JS. Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets. J Cell Biol. 1992;119:905-12.
    • (1992) J Cell Biol , vol.119 , pp. 905-912
    • Lipfert, L.1    Haimovich, B.2    Schaller, M.D.3    Cobb, B.S.4    Parsons, J.T.5    Brugge, J.S.6
  • 2
    • 0026700191 scopus 로고
    • Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate
    • Zachary I, Sinnett-Smith J, Rozengurt E. Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate. J Biol Chem. 1992;267:19031-4.
    • (1992) J Biol Chem , vol.267 , pp. 19031-19034
    • Zachary, I.1    Sinnett-Smith, J.2    Rozengurt, E.3
  • 3
    • 0029120440 scopus 로고
    • Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
    • Ilic D, Furuta Y, Kanazawa S, Takeda N, Sobue K, Nakatsuji N, et al. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature. 1995;377:539-44.
    • (1995) Nature , vol.377 , pp. 539-544
    • Ilic, D.1    Furuta, Y.2    Kanazawa, S.3    Takeda, N.4    Sobue, K.5    Nakatsuji, N.6
  • 4
    • 0029948080 scopus 로고    scopus 로고
    • Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
    • Cary LA, Chang JF, Guan JL. Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J Cell Sci. 1996;109:1787-94. (Pubitemid 26248624)
    • (1996) Journal of Cell Science , vol.109 , Issue.7 , pp. 1787-1794
    • Cary, L.A.1    Chang, J.F.2    Guan, J.-L.3
  • 6
    • 0031740326 scopus 로고
    • Enterocytic differentiation of human Caco-2 cell line correlates with alterations in integrin signaling
    • Levy P, Robin H, Kornprobst M, Capeau J, Cherqui G. Enterocytic differentiation of human Caco-2 cell line correlates with alterations in integrin signaling. J Cell Physiol. 1989;177:618-27.
    • (1989) J Cell Physiol , vol.177 , pp. 618-627
    • Levy, P.1    Robin, H.2    Kornprobst, M.3    Capeau, J.4    Cherqui, G.5
  • 8
    • 0036001167 scopus 로고    scopus 로고
    • The focal adhesion kinase - A regulator of cell migration and invasion
    • DOI 10.1080/15216540211470
    • Hauck CR, Hsia DA, Schlaepfer DD. The focal adhesion kinase-a regulator of cell migration and invasion. IUBMB Life. 2002;53:115-9. (Pubitemid 34553132)
    • (2002) IUBMB Life , vol.53 , Issue.2 , pp. 115-119
    • Hauck, C.R.1    Hsia, D.A.2    Schlaepfer, D.D.3
  • 9
    • 0029039421 scopus 로고
    • Overexpression of focal adhesion kinase (p125FAK) in invasive human tumors
    • Owens LV, Xu L, Craven RJ, Dent GA, Weiner TM, Kornberg L, et al. Overexpression of focal adhesion kinase (p125FAK) in invasive human tumors. Cancer Res. 1995;55:2752-5.
    • (1995) Cancer Res , vol.55 , pp. 2752-2755
    • Owens, L.V.1    Xu, L.2    Craven, R.J.3    Dent, G.A.4    Weiner, T.M.5    Kornberg, L.6
  • 11
    • 0035392952 scopus 로고    scopus 로고
    • 2-terminal FAK in the nuclei of apoptotic glioblastoma cells
    • Jones G, Machado Jr J, Merlo A. Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor dependent migration and induces aggregation of NH2-terminal FAK in the nuclei of apoptotic glioblastoma cells. Cancer Res. 2001;61:4978-81. (Pubitemid 32681522)
    • (2001) Cancer Research , vol.61 , Issue.13 , pp. 4978-4981
    • Jones, G.1    Machado Jr., J.2    Merlo, A.3
  • 15
    • 77956335478 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor (HDACI) PCI-24781 potentiates cytotoxic effects of doxorubicin in bone sarcoma cells
    • Yang C, Choy E, Hornicek FJ, Wood KB, Schwab JH, Liu X, et al. Histone deacetylase inhibitor (HDACI) PCI-24781 potentiates cytotoxic effects of doxorubicin in bone sarcoma cells. Cancer Chemother Pharmacol. 2011;67:439-46.
    • (2011) Cancer Chemother Pharmacol , vol.67 , pp. 439-446
    • Yang, C.1    Choy, E.2    Hornicek, F.J.3    Wood, K.B.4    Schwab, J.H.5    Liu, X.6
  • 16
    • 77956311554 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor valproic acid sensitizes human and canine osteosarcoma to doxorubicin
    • Wittenburg LA, Bisson L, Rose BJ, Korch C, Thamm DH. The histone deacetylase inhibitor valproic acid sensitizes human and canine osteosarcoma to doxorubicin. Cancer Chemother Pharmacol. 2011;67:83-92.
    • (2011) Cancer Chemother Pharmacol , vol.67 , pp. 83-92
    • Wittenburg, L.A.1    Bisson, L.2    Rose, B.J.3    Korch, C.4    Thamm, D.H.5
  • 17
    • 33644850775 scopus 로고    scopus 로고
    • The role of high-dose therapy and autologous stem cell transplantation for pediatric bone and soft tissue sarcomas
    • DOI 10.1586/14737140.6.2.225
    • Ek ET, Choong PF. The role of high-dose therapy and autologous stem cell transplantation for pediatric bone and soft tissue sarcomas. Expert Rev Anticancer Ther. 2006;6:225-37. (Pubitemid 44192934)
    • (2006) Expert Review of Anticancer Therapy , vol.6 , Issue.2 , pp. 225-237
    • Ek, E.T.H.1    Choong, P.F.M.2
  • 19
    • 0034717285 scopus 로고    scopus 로고
    • Anti-apoptotic role of focal adhesion kinase (FAK): Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60
    • DOI 10.1074/jbc.275.21.16309
    • Sonoda Y, Matsumoto Y, Funakoshi M, Yamamoto D, Hanks SK, Kasahara T. Anti-apoptotic role of focal adhesion kinase (FAK) induction of inhibitor-of -apoptosis proteins and apoptosis suppression by the overexpression of FAK in human leukemic cell line, HL-60. J Biol Chem. 2000;275:16309-15. (Pubitemid 30366946)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.21 , pp. 16309-16315
    • Sonoda, Y.1    Matsumoto, Y.2    Funakoshi, M.3    Yamamoto, D.4    Hanks, S.K.5    Kasahara, T.6
  • 20
    • 0038016865 scopus 로고    scopus 로고
    • Focal adhesions and associated proteins in medullary thyroid carcinoma cells
    • DOI 10.1016/S0022-4804(03)00000-0
    • Kim LT, Fleming JB, Lopez-Guzman C, Nwariaku F. Focal adhesions and associated proteins in medullary thyroid carcinoma cells. J Surg Res. 2003;111:177-84. (Pubitemid 36808907)
    • (2003) Journal of Surgical Research , vol.111 , Issue.2 , pp. 177-184
    • Kim, L.T.1    Fleming, J.B.2    Lopez-Guzman, C.3    Nwariaku, F.4
  • 21
    • 0036095459 scopus 로고    scopus 로고
    • Caspase 3-mediated focal adhesion kinase processing in human ovarian cancer cells: Possible regulation by X-linked inhibitor of apoptosis protein
    • DOI 10.1006/gyno.2002.6632
    • Sasaki H, Kotsuji F, Tsang BK. Caspase 3-mediated focal adhesion kinase processing in human ovarian cancer cells: possible regulation by x-linked inhibitor of apoptosis protein. Gynecol Oncol. 2002;85:339-50. (Pubitemid 34522996)
    • (2002) Gynecologic Oncology , vol.85 , Issue.2 , pp. 339-350
    • Sasaki, H.1    Kotsuji, F.2    Tsang, B.K.3
  • 22
    • 33846445804 scopus 로고    scopus 로고
    • Current concepts in apoptosis: The physiological suicide program revisited
    • DOI 10.2478/s11658-006-0041-3
    • Chowdhury I, Tharakan B, Bhat GK. Current concepts in apoptosis: the physiological suicide program revisited. Cell Mol Biol Lett. 2006;11:506-25. (Pubitemid 46708878)
    • (2006) Cellular and Molecular Biology Letters , vol.11 , Issue.4 , pp. 506-525
    • Chowdhury, I.1    Tharakan, B.2    Bhat, G.K.3
  • 23
    • 0040298568 scopus 로고    scopus 로고
    • Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • DOI 10.1074/jbc.273.16.9357
    • Janicke RU, Sprengart ML, Wati MR, Porter AG. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J Biol Chem. 1998;273:9357-60. (Pubitemid 28183012)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.16 , pp. 9357-9360
    • Janicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4
  • 24
    • 12244268624 scopus 로고    scopus 로고
    • Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death?
    • DOI 10.1242/jcs.00210
    • Cande C, Cecconi F, Dessen P, Kroemer G. Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J Cell Sci. 2002;115:4727-34. (Pubitemid 36054627)
    • (2002) Journal of Cell Science , vol.115 , Issue.24 , pp. 4727-4734
    • Cande, C.1    Cecconi, F.2    Dessen, P.3    Kroemer, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.