Transplantation of mesenchymal stem cells exerts anti-apoptotic effects in adult rats after spinal cord ischemia-reperfusion injury

Brain Research

Volumn 1561, Issue , 2014, Pages 1-10

  Yin, Fei ^a   Guo, Li ^b   Meng, Chun Yang ^a   Liu, Ya Juan ^b   Lu, Ri Feng ^b   Li, Peng ^b   Zhou, Yu Bo ^b  

^a THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

Author keywords

Anti apoptosis; Mesenchymal stem cells; Spinal cord ischemia reperfusion injury; Transplantation

Indexed keywords

BAX PROTEIN, RAT; CASP3 PROTEIN, RAT; CASPASE 3; NEUROFILAMENT PROTEIN; NEUROFILAMENT PROTEIN H; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ASTROCYTE; CELL CULTURE; CONVALESCENCE; HINDLIMB; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; MOTOR ACTIVITY; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REPERFUSION INJURY; SPINAL CORD; SPINAL CORD ISCHEMIA; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; ASTROCYTES; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELLS, CULTURED; HINDLIMB; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MOTOR ACTIVITY; NEUROFILAMENT PROTEINS; NEUROGENESIS; NEURONS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; REPERFUSION INJURY; SPINAL CORD; SPINAL CORD ISCHEMIA;

EID: 84898781062     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.02.047     Document Type: Article

References (47)

1. J.M. Adams, and S. Cory The Bcl-2 protein family: arbiters of cell survival Science 281 5381 1998 1322 1326
2. T.E. Allsopp, S. Wyatt, H.F. Paterson, and A.M. Davies The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis Cell 73 2 1993 295 307
3. T.E. Barros Filho, and A.E. Molina Analysis of the sensitivity and reproducibility of the Basso, Beattie, Bresnahan (BBB) scale in Wistar rats Clinics 63 1 2008 103 108
4. S. Barut, Y.A. Unlu, A. Karaoglan, M. Tuncdemir, F.K. Dagistanli, M. Ozturk, and A. Colak The neuroprotective effects of z-DEVD.fmk, a caspase-3 inhibitor, on traumatic spinal cord injury in rats Surg. Neurol. 64 3 2005 213 220 (discussion 220)
5. O. Cakir, K. Erdem, A. Oruc, N. Kilinc, and N. Eren Neuroprotective effect of N-acetylcysteine and hypothermia on the spinal cord ischemia-reperfusion injury Cardiovasc. Surg. 11 5 2003 375 379
6. C.S. Cina, L. Abouzahr, G.O. Arena, A. Lagana, P.J. Devereaux, and F. Farrokhyar Cerebrospinal fluid drainage to prevent paraplegia during thoracic and thoracoabdominal aortic aneurysm surgery: a systematic review and meta-analysis J. Vasc. Surg. 40 1 2004 36 44
7. A. Colak, A. Karaoglan, S. Barut, S. Kokturk, A.I. Akyildiz, and M. Tasyurekli Neuroprotection and functional recovery after application of the caspase-9 inhibitor z-LEHD-fmk in a rat model of traumatic spinal cord injury J. Neurosurg. Spine 2 3 2005 327 334
8. A. Diaz-Ruiz, H. Salgado-Ceballos, S. Montes, G. Guizar-Sahagun, N. Gelista-Herrera, M. Mendez-Armenta, S. Diaz-Cintra, and C. Rios Delayed administration of dapsone protects from tissue damage and improves recovery after spinal cord injury J. Neurosci. Res. 89 3 2011 373 380
9. H. Dolgun, Z. Sekerci, E. Turkoglu, H. Kertmen, E.R. Yilmaz, M. Anlar, I.B. Erguder, and H. Tuna Neuroprotective effect of mesna (2-mercaptoethane sulfonate) against spinal cord ischemia/reperfusion injury in rabbits J. Clin. Neurosci. 17 4 2010 486 489
10. J. Fan, G. Xu, D.J. Nagel, Z. Hua, N. Zhang, and G. Yin A model of ischemia and reperfusion increases JNK activity, inhibits the association of BAD and 14-3-3, and induces apoptosis of rabbit spinal neurocytes Neurosci. Lett. 473 3 2010 196 201
11. A. Gross, J. Jockel, M.C. Wei, and S.J. Korsmeyer Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis EMBO J. 17 14 1998 3878 3885
12. J. Guan, F. Wang, Z. Li, J. Chen, X. Guo, J. Liao, and N.I. Moldovan The stimulation of the cardiac differentiation of mesenchymal stem cells in tissue constructs that mimic myocardium structure and biomechanics Biomaterials 32 24 2011 5568 5580
13. J.M. Guerit, and R.A. Dion State-of-the-art of neuromonitoring for prevention of immediate and delayed paraplegia in thoracic and thoracoabdominal aorta surgery Ann. Thorac. Surg. 74 5 2002 S1867 S1869 (discussion S1892-1868)
14. L. Guo, F. Yin, H.Q. Meng, L. Ling, T.N. Hu-He, P. Li, C.X. Zhang, S. Yu, D.S. Duan, and H.X. Fan Differentiation of mesenchymal stem cells into dopaminergic neuron-like cells in vitro Biomed. Environ. Sci. 18 1 2005 36 42
15. T. Hayashi, M. Sakurai, K. Abe, M. Sadahiro, K. Tabayashi, and Y. Itoyama Apoptosis of motor neurons with induction of caspases in the spinal cord after ischemia Stroke 29 5 1998 1007 1012 (discussion 1013)
16. Y.T. Hsu, and R.J. Youle Nonionic detergents induce dimerization among members of the Bcl-2 family J. Biol. Chem. 272 21 1997 13829 13834
17. G. Jin, G. Qiu, D. Wu, Y. Hu, P. Qiao, C. Fan, and F. Gao Allogeneic bone marrow-derived mesenchymal stem cells attenuate hepatic ischemia-reperfusion injury by suppressing oxidative stress and inhibiting apoptosis in rats Int. J. Mol. Med. 31 6 2013 1395 1401
18. M. Kakinohana, K. Kida, S. Minamishima, D.N. Atochin, P.L. Huang, M. Kaneki, and F. Ichinose Delayed paraplegia after spinal cord ischemic injury requires caspase-3 activation in mice Stroke 42 8 2011 2302 2307
19. D.J. Kane, T.A. Sarafian, R. Anton, H. Hahn, E.B. Gralla, J.S. Valentine, T. Ord, and D.E. Bredesen Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species Science 262 5137 1993 1274 1277
20. G.K. Kanellopoulos, H. Kato, Y. Wu, D. Dougenis, M. Mackey, C.Y. Hsu, and N.T. Kouchoukos Neuronal cell death in the ischemic spinal cord: the effect of methylprednisolone Ann. Thorac. Surg. 64 5 1997 1279 1285 (discussion 1286)
21. R.R. Kotipatruni, V.R. Dasari, K.K. Veeravalli, D.H. Dinh, D. Fassett, and J.S. Rao p53- and Bax-mediated apoptosis in injured rat spinal cord Neurochem. Res. 36 11 2011 2063 2074
22. G. Kroemer The proto-oncogene Bcl-2 and its role in regulating apoptosis Nat. Med. 3 6 1997 614 620
23. J.K. Lee, H.K. Jin, and J.S. Bae Bone marrow-derived mesenchymal stem cells attenuate amyloid beta-induced memory impairment and apoptosis by inhibiting neuronal cell death Curr. Alzheimer Res 7 6 2010 540 548
24. M. Li, V.O. Ona, M. Chen, M. Kaul, L. Tenneti, X. Zhang, P.E. Stieg, S.A. Lipton, and R.M. Friedlander Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury Neuroscience 99 2 2000 333 342
25. P. Li, D. Nijhawan, I. Budihardjo, S.M. Srinivasula, M. Ahmad, E.S. Alnemri, and X. Wang Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade Cell 91 4 1997 479 489
26. C. Liu, Z. Shi, L. Fan, C. Zhang, K. Wang, and B. Wang Resveratrol improves neuron protection and functional recovery in rat model of spinal cord injury Brain Res. 1374 16 2011 100 109
27. M.E. Mackey, Y. Wu, R. Hu, J.A. DeMaro, M.F. Jacquin, G.K. Kanellopoulos, C.Y. Hsu, and N.T. Kouchoukos Cell death suggestive of apoptosis after spinal cord ischemia in rabbits Stroke 28 10 1997 2012 2017
28. P.M. Markus, S. Koenig, P. Krause, and H. Becker Selective intraportal transplantation of DiI-marked isolated rat hepatocytes Cell Transplant. 6 1997 455 462
29. R. Perrot, R. Berges, A. Bocquet, and J. Eyer Review of the multiple aspects of neurofilament functions, and their possible contribution to neurodegeneration Mol Neurobiol. 38 2008 27 65
30. M. Raisova, A.M. Hossini, J. Eberle, C. Riebeling, T. Wieder, I. Sturm, P.T. Daniel, C.E. Orfanos, and C.C. Geilen The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis J. Investig. Dermatol. 117 2 2001 333 340
31. J.C. Reed Double identity for proteins of the Bcl-2 family Nature 387 6635 1997 773 776
32. M. Sakurai, T. Hayashi, K. Abe, M. Sadahiro, and K. Tabayashi Delayed selective motor neuron death and fas antigen induction after spinal cord ischemia in rabbits Brain. Res. 797 1 1998 23 28
33. T. Sato, Y. Iso, T. Uyama, K. Kawachi, K. Wakabayashi, Y. Omori, T. Soda, M. Shoji, S. Koba, S. Yokoyama, N. Fukuda, S. Saito, T. Katagiri, Y. Kobayashi, Y. Takeyama, A. Umezawa, and H. Suzuki Coronary vein infusion of multipotent stromal cells from bone marrow preserves cardiac function in swine ischemic cardiomyopathy via enhanced neovascularization Lab. Investig. 91 4 2011 553 564
34. C.L. Sentman, J.R. Shutter, D. Hockenbery, O. Kanagawa, and S.J. Korsmeyer Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes Cell 67 5 1991 879 888
35. S.L. Shuman, J.C. Bresnahan, and M.S. Beattie Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats J. Neurosci. Res. 50 5 1997 798 808
36. R. Soler, C. Fullhase, A. Hanson, L. Campeau, C. Santos, and K.E. Andersson Stem cell therapy ameliorates bladder dysfunction in an animal model of parkinson disease J. Urol. 187 4 2012 1491 1497
37. J.E. Springer, R.D. Azbill, and P.E. Knapp Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury Nat. Med. 5 8 1999 943 946
38. C. Stamm, B. Westphal, H.D. Kleine, M. Petzsch, C. Kittner, H. Klinge, C. Schumichen, C.A. Nienaber, M. Freund, and G. Steinhoff Autologous bone-marrow stem-cell transplantation for myocardial regeneration Lancet 361 9351 2003 45 46
39. F. Tian, L.H. Xu, W. Zhao, L.J. Tian, and X.L. Ji The optimal therapeutic timing and mechanism of puerarin treatment of spinal cord ischemia-reperfusion injury in rats J. Ethnopharmacol. 134 3 2011 892 896
40. Y. Wang, Z. Sun, K. Zhang, G. Xu, and G. Li Bcl-2 in suppressing neuronal apoptosis after spinal cord injury World J. Emerg. Med. 2 1 2011 38 44
41. L. Wei, J.L. Fraser, Z.Y. Lu, X. Hu, and S.P. Yu Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after cerebral ischemia in rats Neurobiol. Dis. 46 3 2012 635 645
42. K.J. Woo, Y.H. Yoo, J.W. Park, and T.K. Kwon Bcl-2 attenuates anticancer agents-induced apoptosis by sustained activation of Akt/protein kinase B in U937 cells Apoptosis 10 6 2005 1333 1343
43. J.T. Yabe, F.S. Wang, T. Chylinski, T. Katchmar, and T.B. Shea Selective accumulation of the high molecular weight neurofilament subunit within the distal region of growing axonal neurites Cell Motil Cytoskeleton. 50 2001 1 12
44. A.G. Yakovlev, S.M. Knoblach, L. Fan, G.B. Fox, R. Goodnight, and A.I. Faden Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury J. Neurosci. 17 19 1997 7415 7424
45. R.J. Youle, and A. Strasser The BCL-2 protein family: opposing activities that mediate cell death Nat. Rev. Mol. Cell Biol. 9 1 2008 47 59
46. J.A. Zivin, and U. DeGirolami Spinal cord infarction: a highly reproducible stroke model Stroke 11 2 1980 200 202
47. D.A. Zvara, D.M. Colonna, D.D. Deal, J.C. Vernon, M. Gowda, and J.C. Lundell Ischemic preconditioning reduces neurologic injury in a rat model of spinal cord ischemia Ann. Thorac. Surg. 68 3 1999 874 880