Identification of Redeye, a new sleepregulating protein whose expression is modulated by sleep amount

eLife

Volumn 2014, Issue 3, 2014, Pages

  Shi, Mi ^a   Yue, Zhifeng ^a   Kuryatov, Alexandre ^b   Lindstrom, Jon M ^b   Sehgal, Amita ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINIC RECEPTOR; PROTEIN; REDEYE PROTEIN; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA4 SUBUNIT; REDEYE PROTEIN, DROSOPHILA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN ELECTROPHYSIOLOGY; BRAIN MAPPING; CHEMICAL MUTAGENESIS; CHROMOSOME; CIRCADIAN RHYTHM; CONTROLLED STUDY; FEMALE; GENE MAPPING; HOMOZYGOTE; IMMUNOCYTOCHEMISTRY; MALE; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; REM SLEEP; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SLEEP; SLEEP DEPRIVATION; ANIMAL; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; HOMEOSTASIS; METABOLISM; MUTATION; PHOTOPERIODICITY; SIGNAL TRANSDUCTION; TIME;

ANIMALS; CIRCADIAN RHYTHM; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GENOTYPE; HOMEOSTASIS; MUTATION; PHENOTYPE; PHOTOPERIOD; RECEPTORS, NICOTINIC; SIGNAL TRANSDUCTION; SLEEP; TIME FACTORS;

EID: 84898756782     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.01473     Document Type: Article

References (30)

1. Allebrandt KV, Amin N, Muller-Myhsok B, Esko T, Teder-Laving M, Azevedo RV, Hayward C, Van Mill J, Vogelzangs N, Green EW, Melville SA, Lichtner P, Wichmann HE, Oostra BA, Janssens AC, Campbell H, Wilson JF, Hicks AA, Pramstaller PP, Dogas Z, Rudan I, Merrow M, Penninx B, Kyriacou CP, Metspalu A, Van Duijn CM, Meitinger T, Roenneberg T. 2013. A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila. Molecular Psychiatry 18:122-132. doi: 10.1038/mp.2011.142mp2011142.
2. Borbely AA. 1982. A two process model of sleep regulation. Human Neurobiology 1:195-204.
3. Cirelli C. 2009. The genetic and molecular regulation of sleep: from fruit flies to humans. Nature Reviews Neuroscience 10:549-560. doi: 10.1038/nrn2683.
4. Cirelli C, Bushey D, Hill S, Huber R, Kreber R, Ganetzky B, Tononi G. 2005. Reduced sleep in Drosophila Shaker mutants. Nature 434:1087-1092. doi: 10.1038/nature03486.
5. Dean T, Xu R, Joiner W, Sehgal A, Hoshi T. 2011. Drosophila QVR/SSS modulates the activation and C-type inactivation kinetics of Shaker K(+) channels. The Journal of Neuroscience 31:11387-11395. doi: 10.1523/JNEUROSCI.0502-11.2011.
6. Gilestro GF, Cirelli C. 2009. pySolo: a complete suite for sleep analysis in Drosophila. Bioinformatics 25:1466-1467. doi: 10.1093/bioinformatics/btp237btp237.
7. Hendricks JC, Lu S, Kume K, Yin JC, Yang Z, Sehgal A. 2003. Gender dimorphism in the role of cycle (BMAL1) in rest, rest regulation, and longevity in Drosophila melanogaster. Journal of Biological Rhythms 18:12-25. doi: 10.1177/0748730402239673.
8. Joho RH, Marks GA, Espinosa F. 2006. Kv3 potassium channels control the duration of different arousal states by distinct stochastic and clock-like mechanisms. European Journal of Neuroscience 23:1567-1574. doi: 10.1111/j.1460-9568.2006.04672.x.
9. Koh K, Joiner WJ, Wu MN, Yue Z, Smith CJ, Sehgal A. 2008. Identification of SLEEPLESS, a sleep-promoting factor. Science 321:372-376. doi: 10.1126/science.1155942.
10. Kume K, Kume S, Park SK, Hirsh J, Jackson FR. 2005. Dopamine is a regulator of arousal in the fruit fly. The Journal of Neuroscience 25:7377-7384. doi: 10.1523/JNEUROSCI.2048-05.2005.
11. Kuryatov A, Lindstrom J. 2011. Expression of functional human alpha6beta2beta3* acetylcholine receptors in Xenopus laevis oocytes achieved through subunit chimeras and concatamers. Molecular Pharmacology 79:126-140. doi: 10.1124/mol.110.066159.
12. Lansdell SJ, Millar NS. 2000. Cloning and heterologous expression of Dalpha4, a Drosophila neuronal nicotinic acetylcholine receptor subunit: identification of an alternative exon influencing the efficiency of subunit assembly. Neuropharmacology 39:2604-2614. doi: 10.1016/S0028-3908(00)00111-8.
13. Lindstrom JM. 2003. Nicotinic acetylcholine receptors of muscles and nerves: comparison of their structures, functional roles, and vulnerability to pathology. Annals of the New York Academy of Sciences 998:41-52. doi: 10.1196/annals.1254.007.
14. Luo W, Sehgal A. 2012. Regulation of circadian behavioral output via a MicroRNA-JAK/STAT circuit. Cell 148:765-779. doi: 10.1016/j.cell.2011.12.024.
15. Maret S, Dorsaz S, Gurcel L, Pradervand S, Petit B, Pfister C, Hagenbuchle O, O'hara BF, Franken P, Tafti M. 2007. Homer1a is a core brain molecular correlate of sleep loss. Proceedings of the National Academy of Sciences of the United States of America 104:20090-20095. doi: 10.1073/pnas.0710131104.
16. Millar NS. 2009. A review of experimental techniques used for the heterologous expression of nicotinic acetylcholine receptors. Biochemical Pharmacology 78:766-776. doi: 10.1016/j.bcp.2009.06.015.
17. Millar NS, Lansdell SJ. 2010. Characterisation of insect nicotinic acetylcholine receptors by heterologous expression. Advances in Experimental Medicine and Biology 683:65-73. doi: 10.1007/978-1-4419-6445-8_6.
18. Miwa JM, Freedman R, Lester HA. 2011. Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses. Neuron 70:20-33. doi: 10.1016/j.neuron.2011.03.014.
19. Naidoo N, Casiano V, Cater J, Zimmerman J, Pack AI. 2007. A role for the molecular chaperone protein BiP/GRP78 in Drosophila sleep homeostasis. Sleep 30:557-565.
20. Nelson SE, Duricka DL, Campbell K, Churchill L, Krueger JM. 2004. Homer1a and 1bc levels in the rat somatosensory cortex vary with the time of day and sleep loss. Neuroscience Letters 367:105-108. doi: 10.1016/j.neulet.2004.05.089.
21. Platt B, Riedel G. 2011. The cholinergic system, EEG and sleep. Behavioural Brain Research 221:499-504. doi: 10.1016/j.bbr.2011.01.017.
22. Ryder E, Blows F, Ashburner M, Bautista-Llacer R, Coulson D, Drummond J, Webster J, Gubb D, Gunton N, Johnson G, O'kane CJ, Huen D, Sharma P, Asztalos Z, Baisch H, Schulze J, Kube M, Kittlaus K, Reuter G, Maroy P, Szidonya J, Rasmuson-Lestander A, Ekstrom K, Dickson B, Hugentobler C, Stocker H, Hafen E, Lepesant JA, Pflugfelder G, Heisenberg M, Mechler B, Serras F, Corominas M, Schneuwly S, Preat T, Roote J, Russell S. 2004. The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics 167:797-813. doi: 10.1534/genetics.104.026658.
23. Saper CB, Fuller PM, Pedersen NP, Lu J, Scammell TE. 2010. Sleep state switching. Neuron 68:1023-1042. doi: 10.1016/j.neuron.2010.11.032.
24. Sehgal A, Mignot E. 2011. Genetics of sleep and sleep disorders. Cell 146:194-207. doi: 10.1016/j.cell.2011.07.004.
25. Seugnet L, Boero J, Gottschalk L, Duntley SP, Shaw PJ. 2006. Identification of a biomarker for sleep drive in flies and humans. Proceedings of the National Academy of Sciences of the United States of America 103:19913-19918. doi: 10.1073/pnas.0609463104.
26. Stavropoulos N, Young MW. 2011. insomniac and Cullin-3 regulate sleep and wakefulness in Drosophila. Neuron 72:964-976. doi: 10.1016/j.neuron.2011.12.003.
27. Suzuki A, Sinton CM, Greene RW, Yanagisawa M. 2013. Behavioral and biochemical dissociation of arousal and homeostatic sleep need influenced by prior wakeful experience in mice. Proceedings of the National Academy of Sciences of the United States of America 110:10288-10293. doi: 10.1073/pnas.1308295110.
28. Ueno T, Tomita J, Tanimoto H, Endo K, Ito K, Kume S, Kume K. 2012. Identification of a dopamine pathway that regulates sleep and arousal in Drosophila. Nature Neuroscience 15:1516-1523. doi: 10.1038/nn.3238.
29. Wu MN, Joiner WJ, Dean T, Yue Z, Smith CJ, Chen D, Hoshi T, Sehgal A, Koh K. 2010. SLEEPLESS, a Ly-6/neurotoxin family member, regulates the levels, localization and activity of Shaker. Nature Neuroscience 13:69-75. doi: 10.1038/nn.2454.
30. Zheng X, Sehgal A. 2012. Speed control: cogs and gears that drive the circadian clock. Trends in Neurosciences 35:574-585. doi: 10.1016/j.tins.2012.05.007.