Does reevaluation of colorectal cancers with inadequate nodal yield lead to stage migration or the identification of metastatic lymph nodes?

Diseases of the Colon and Rectum

Volumn 57, Issue 4, 2014, Pages 432-437

  Chen, Lilian ^a   Kalady, Matthew F ^b   Goldblum, John ^b   Seyidova Khoshknabi, Dilara ^b   Burks, Eric J ^a   Roberts, Patricia L ^a   Ricciardi, Rocco ^a  

^a LAHEY HOSPITAL AND MEDICAL CENTER   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Benchmark; Colorectal cancer; Lymph nodes; Pathology; Quality

Indexed keywords

ADIPOSE TISSUE; ADJUVANT CHEMOTHERAPY; ADULT; AGED; CANCER STAGING; COLORECTAL CANCER; CONFERENCE PAPER; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; LYMPH NODE RATIO; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; RETROSPECTIVE STUDY; SAMPLE SIZE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; HUMANS; INTRA-ABDOMINAL FAT; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; RETROSPECTIVE STUDIES;

EID: 84898724528     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1097/DCR.0000000000000052     Document Type: Conference Paper

References (26)

1. Le Voyer TE, Sigurdson ER, Hanlon AL, et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol. 2003;21:2912-2919.
2. Johnson PM, Porter GA, Ricciardi R, Baxter NN. Increasing negative lymph node count is independently associated with improved long-term survival in stage IIB and IIC colon cancer. J Clin Oncol. 2006;24:3570-3575.
3. Swanson RS, Compton CC, Stewart AK, Bland KI. The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. Ann Surg Oncol. 2003;10:65-71.
4. Berger AC, Sigurdson ER, LeVoyer T, et al. Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol. 2005;23:8706-8712.
5. Fielding LP, Arsenault PA, Chapuis PH, et al. Clinicopathological staging for colorectal cancer: an International Documentation System (IDS) and an International Comprehensive Anatomical Terminology (ICAT ). J Gastroenterol Hepatol. 1991;6:325-344.
6. Prandi M, Lionetto R, Bini A, et al. Prognostic evaluation of stage B colon cancer patients is improved by an adequate lymphadenectomy: results of a secondary analysis of a large scale adjuvant trial. Ann Surg. 2002;235:458-463.
7. Caplin S, Cerottini JP, Bosman FT, Constanda MT, Givel JC. For patients with Dukes' B (TNM Stage II) colorectal carcinoma, examination of six or fewer lymph nodes is related to poor prognosis. Cancer. 1998;83:666-672.
8. Pocard M, Panis Y, Malassagne B, et al. Assessing the effectiveness of mesorectal excision in colorectal cancer. Dis Colon Rectum. 1998;41:839-845.
9. Nelson H, Petrelli N, Carlin A, et al. Guidelines 2000 for colon and rectal surgery. J Natl Cancer Inst. 2001;93:583-596.
10. Tepper JE, O'Connell MJ, Niedzwiecki D, et al. Impact of number of nodes retrieved on outcome in patients with rectal cancer. J Clin Oncol. 2001;19:157-163.
11. Joseph NE, Sigurdson ER, Hanlon AL, et al. Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. Ann Surg Oncol. 2003;10:213-218.
12. Sarli L, Bader G, Iusco D, et al. Number of lymph nodes examined and prognosis of TNM stage II colorectal cancer. Eur J Cancer. 2005;41:272-279.
13. Maurel J, Launoy G, Grosclaude P, et al. Lymph node harvest reporting in patients with carcinoma of the large bowel: a French population-based study. Cancer. 1998;82:1482-1486.
14. Goldstein NS. Lymph node recoveries from 2427 pT3 colorectal resection specimens spanning 45 years: recommendations for a minimum number of recovered lymph nodes based on predictive probabilities. Am J Surg Pathol. 2002;26:179-189.
15. Wong JH, Severino R, Honnebier MB, Tom P, Namiki TS. Number of nodes examined and staging accuracy in colorectal carcinoma. J Clin Oncol. 1999;17:2896-2900.
16. Shanmugam C, Hines RB, Jhala NC, et al. Evaluation of lymph node numbers for adequate staging of Stage II and II colon cancer. J Hematol Oncol. 2011;4:25.
17. National Quality forum endorsed commission on cancer measures for quality of cancer care for breast and colorectal cancers. American College of Surgeons Commission on Cancer; 2007. Available at: http://www.facs.org/cancer/ qualitymeasures.html. Accessed June 13, 2012.
18. National Quality Forum. Available at: https://www.qualityforum.org/. Accessed January 30, 2014.
19. Bilimoria KY, Bentrem DJ, Stewart AK, et al. Lymph node evaluation as a colon cancer quality measure: a national hospital report card. J Natl Cancer Inst. 2008;100:1310-1317.
20. Kukreja SS, Esteban-Agusti E, Velasco JM, Hieken TJ. Increased lymph node evaluation with colorectal cancer resection: does it improve detection of stage II disease? Arch Surg. 2009;144:612-617.
21. National Comprehensive Cancer Network. Practice Guidelines in Oncology - Colon Cancer. Version 2.2012. Available at: http://www.cancernm.org/pdf/NCCN- CRC-Screening-Guidelines-2012.pdf. Accessed on July 5, 2013.
22. Wang J, Hassett JM, Dayton MT, Kulaylat MN. Lymph node ratio: role in the staging of node-positive colon cancer. Ann Surg Oncol. 2008;15:1600-1608.
23. Baxter NN, Virnig DJ, Rothenberger DA, Morris AM, Jessurun J, Virnig BA. Lymph node evaluation in colorectal cancer patients: a population-based study. J Natl Cancer Inst. 2005;97:219-225.
24. Bilimoria KY, Stewart AK, Palis BE, Bentrem DJ, Talamonti MS, Ko CY. Adequacy and importance of lymph node evaluation for colon cancer in the elderly. J Am Coll Surg. 2008;206:247-254.
25. Rajput A, Skibber JM, Engstrom PF, et al, Meeting the 12 lymph node benchmark in colorectal cancer surgery: a comparison of NCCN and SER data. J Clin Oncol. 2007;25: 4015
26. Jakub JW, Russell G, Tillman CL, Lariscy C. Colon cancer and low lymph node count: who is to blame? Arch Surg. 2009;144:1115-1120.