Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancer

Journal of Hematology and Oncology

Volumn 4, Issue , 2011, Pages

  Shanmugam, Chandrakumar ^a   Hines, Robert B ^b   Jhala, Nirag C ^c   Katkoori, Venkat R ^a   Zhang, Bin ^a   Posey, James A ^a,d   Bumpers, Harvey L ^e   Grizzle, William E ^a   Eltoum, Isam E ^a   Siegal, Gene P ^a   Manne, Upender ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b GEORGIA SOUTHERN UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d University of Alabama at Birmingham   (United States)

^e MOREHOUSE SCHOOL OF MEDICINE   (United States)

Author keywords

Clinical outcomes; Colon cancer; Lymph nodes; Stage II; Stage III

Indexed keywords

ADULT; AGED; ARTICLE; CANCER MORTALITY; CANCER RECURRENCE; CANCER RISK; CANCER STAGING; CANCER SURVIVAL; CLINICAL EVALUATION; COLON CANCER; FEMALE; HUMAN; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; RECURRENCE RISK; COLON TUMOR; LYMPH NODE METASTASIS; MIDDLE AGED; PATHOLOGY; TREATMENT OUTCOME; TUMOR RECURRENCE;

AGED; AGED, 80 AND OVER; COLONIC NEOPLASMS; FEMALE; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; TREATMENT OUTCOME;

EID: 79957511060     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/1756-8722-4-25     Document Type: Article

References (50)

1. Cancer statistics, 2010. A Jemal R Siegel J Xu E Ward, CA Cancer J Clin 2010 60 277 300 10.3322/caac.20073 20610543
2. Identification of objective pathological prognostic determinants and models of prognosis in Dukes' B colon cancer. VC Petersen KJ Baxter SB Love NA Shepherd, Gut 2002 51 65 69 10.1136/gut.51.1.65 12077094 (Pubitemid 34717746)
3. Who to treat with adjuvant therapy in Dukes B/stage II colorectal cancer? The need for high quality pathology. EJ Morris NJ Maughan D Forman P Quirke, Gut 2007 56 1419 1425 10.1136/gut.2006.116830 17494107 (Pubitemid 47517838)
4. Adjuvant chemotherapy use for Medicare beneficiaries with stage II colon cancer. D Schrag S Rifas-Shiman L Saltz PB Bach CB Begg, J Clin Oncol 2002 20 3999 4005 10.1200/JCO.2002.11.084 12351597
5. Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: who benefits and by how much? S Gill CL Loprinzi DJ Sargent SD Thome SR Alberts DG Haller J Benedetti G Francini LE Shepherd J Francois Seitz R Labianca W Chen SS Cha MP Heldebrant RM Goldberg, J Clin Oncol 2004 22 1797 1806 10.1200/JCO.2004.09.059 15067028 (Pubitemid 41095169)
6. Adjuvant chemotherapy in colorectal cancer: a joint analysis of randomised trials by the Nordic Gastrointestinal Tumour Adjuvant Therapy Group. B Glimelius O Dahl B Cedermark A Jakobsen SM Bentzen H Starkhammar H Gronberg R Hultborn M Albertsson L Pahlman KM Tveit, Acta oncologica (Stockholm, Sweden) 2005 44 904 912 (Pubitemid 41780118)
7. Current issues in adjuvant treatment of stage II colon cancer. T Andre D Sargent J Tabernero M O'Connell M Buyse A Sobrero JL Misset C Boni A de Gramont, Ann Surg Oncol 2006 13 887 898 10.1245/ASO.2006.07.003 16614880 (Pubitemid 43727375)
8. Updated protocol for the examination of specimens from patients with carcinomas of the colon and rectum, excluding carcinoid tumors, lymphomas, sarcomas, and tumors of the vermiform appendix: a basis for checklists. Cancer Committee. CC Compton, Archives of pathology & laboratory medicine 2000 124 1016 1025 21472693 (Pubitemid 30602044)
9. For patients with Dukes' B (TNM Stage II) colorectal carcinoma, examination of six or fewer lymph nodes is related to poor prognosis. S Caplin JP Cerottini FT Bosman MT Constanda JC Givel, Cancer 1998 83 666 672 10.1002/(SICI)1097-0142(19980815)83:4<666::AID-CNCR6>3.0.CO;2-I 9708929 (Pubitemid 28387688)
10. Cancer medicine. GJ Steele J Tepper B Motwani, Philadelphia: Lea & Febiger 3 1993
11. Colorectal adenocarcinoma: quality of the assessment of lymph node metastases. F Hernanz S Revuelta C Redondo C Madrazo J Castillo M Gomez-Fleitas, Diseases of the colon and rectum 1994 37 373 376 discussion 376-377 10.1007/BF02053600 8168417
12. Cancer staging and survival in colon cancer is dependent on the quality of the pathologists' specimen examination. P Jestin L Pahlman B Glimelius U Gunnarsson, Eur J Cancer 2005 41 2071 2078 10.1016/j.ejca.2005.06.012 16125926 (Pubitemid 41337948)
13. Nodal stage of stage III colon cancer: The impact of metastatic lymph node ratio. IJ Park GS Choi SH Jun, J Surg Oncol 2009
14. Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. NE Joseph ER Sigurdson AL Hanlon H Wang RJ Mayer JS MacDonald PJ Catalano DG Haller, Annals of surgical oncology 2003 10 213 218 10.1245/ASO.2003.03.059 12679304 (Pubitemid 40486952)
15. Hospital lymph node examination rates and survival after resection for colon cancer. SL Wong H Ji BK Hollenbeck AM Morris O Baser JD Birkmeyer, Jama 2007 298 2149 2154 10.1001/jama.298.18.2149 18000198 (Pubitemid 350106653)
16. Lymph node evaluation and survival after curative resection of colon cancer: systematic review. GJ Chang MA Rodriguez-Bigas JM Skibber VA Moyer, Journal of the National Cancer Institute 2007 99 433 441 10.1093/jnci/djk092 17374833 (Pubitemid 47073566)
17. Meeting the 12 lymph node (LN) benchmark in colon cancer. A Rajput D Romanus MR Weiser A ter Veer J Niland J Wilson JM Skibber YN Wong A Benson CC Earle D Schrag, J Surg Oncol 2010 102 3 9 10.1002/jso.21532 20578172
18. The prognosis of colon cancer is dependent on accurate staging. LK Temple, J Surg Oncol 2010 102 1 2 10.1002/jso.21591 20578171
19. Clinicopathological staging for colorectal cancer: an International Documentation System (IDS) and an International Comprehensive Anatomical Terminology (ICAT). LP Fielding PA Arsenault PH Chapuis O Dent B Gathright JD Hardcastle P Hermanek JR Jass RC Newland, Journal of gastroenterology and hepatology 1991 6 325 344 10.1111/j.1440-1746.1991.tb00867.x 1912440
20. Guidelines 2000 for colon and rectal cancer surgery. H Nelson N Petrelli A Carlin J Couture J Fleshman J Guillem B Miedema D Ota D Sargent, J Natl Cancer Inst 2001 93 583 596 10.1093/jnci/93.8.583 11309435 (Pubitemid 32409626)
21. American Joint Committee on Cancer, American Cancer Society: AJCC Cancer Staging Manual. SB Edge DR Byrd CC Compton AG Fritz FL Greene A Trotti, New York, NY: Springer-Verlag 7 2010
22. Lymph node counts, rates of positive lymph nodes, and patient survival for colon cancer surgery in Ontario, Canada: a population-based study. L Bui E Rempel D Reeson M Simunovic, Journal of surgical oncology 2006 93 439 445 10.1002/jso.20499 16615148 (Pubitemid 44651266)
23. More extensive nodal dissection improves survival for stages I to III of colon cancer: a population-based study. SL Chen AJ Bilchik, Annals of surgery 2006 244 602 610 16998369
24. Impact of lymph node retrieval and pathological ultra-staging on the prognosis of stage II colon cancer. CH Law FC Wright T Rapanos M Alzahrani SS Hanna M Khalifa AJ Smith, Journal of surgical oncology 2003 84 120 126 10.1002/jso.10309 14598354 (Pubitemid 37363153)
25. Number of lymph nodes examined and prognosis of TNM stage II colorectal cancer. L Sarli G Bader D Iusco C Salvemini DD Mauro A Mazzeo G Regina L Roncoroni, Eur J Cancer 2005 41 272 279 10.1016/j.ejca.2004.10.010 15661553 (Pubitemid 40126960)
26. Prognostic evaluation of stage B colon cancer patients is improved by an adequate lymphadenectomy: results of a secondary analysis of a large scale adjuvant trial. M Prandi R Lionetto A Bini G Francioni G Accarpio A Anfossi E Ballario G Becchi S Bonilauri A Carobbi P Cavaliere D Garcea L Giuliani E Morziani F Mosca A Mussa M Pasqualini D Poddie F Tonetti L Zardo R Rosso, Annals of surgery 2002 235 458 463 10.1097/00000658-200204000-00002 11923600 (Pubitemid 34258343)
27. Lymph node recoveries from 2427 pT3 colorectal resection specimens spanning 45 years: recommendations for a minimum number of recovered lymph nodes based on predictive probabilities. NS Goldstein, The American journal of surgical pathology 2002 26 179 189 10.1097/00000478-200202000-00004 11812939 (Pubitemid 34127497)
28. Non-parametric estimation from incomplete observations. E MP Kaplan, J AM Stat Assoc 1958 53
29. Number of lymph nodes examined and its impact on colorectal cancer staging. J Kim R Huynh I Abraham E Kim RR Kumar, The American surgeon 2006 72 902 905 17058731 (Pubitemid 351837628)
30. Association versus causation versus quality improvement: setting benchmarks for lymph node evaluation in colon cancer. R Ricciardi NN Baxter, Journal of the National Cancer Institute 2007 99 414 415 10.1093/jnci/djk106 17374823 (Pubitemid 47078734)
31. Number of lymph node metastases is better predictor of prognosis than level of lymph node metastasis in patients with node-positive colon cancer. O Suzuki Y Sekishita T Shiono K Ono M Fujimori S Kondo, Journal of the American College of Surgeons 2006 202 732 736 10.1016/j.jamcollsurg.2006.02.007 16648012
32. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. TE Le Voyer ER Sigurdson AL Hanlon RJ Mayer JS Macdonald PJ Catalano DG Haller, J Clin Oncol 2003 21 2912 2919 10.1200/JCO.2003.05.062 12885809 (Pubitemid 46621841)
33. Accurate lymph-node detection in colorectal specimens resected for cancer is of prognostic significance. C Ratto L Sofo M Ippoliti M Merico M Bossola FM Vecchio GB Doglietto F Crucitti, Diseases of the colon and rectum 1999 42 143 154 discussion 154-148 10.1007/BF02237119 10211489
34. The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. RS Swanson CC Compton AK Stewart KI Bland, Annals of surgical oncology 2003 10 65 71 10.1245/ASO.2003.03.058 12513963
35. Lymph node recovery from colorectal tumor specimens: recommendation for a minimum number of lymph nodes to be examined. F Cianchi A Palomba V Boddi L Messerini F Pucciani G Perigli P Bechi C Cortesini, World J Surg 2002 26 384 389 10.1007/s00268-001-0236-8 11865379 (Pubitemid 36920420)
36. Survival in stage III colon cancer is independent of the total number of lymph nodes retrieved. VL Tsikitis DL Larson BG Wolff G Kennedy N Diehl R Qin EJ Dozois RR Cima, J Am Coll Surg 2009 208 42 47 10.1016/j.jamcollsurg.2008.10.013 19228501
37. Nodal stage of stage III colon cancer: the impact of metastatic lymph node ratio. IJ Park GS Choi SH Jun, Journal of surgical oncology 2009 100 240 243 10.1002/jso.21273 19330780
38. Impact of socioeconomic status on extent of lymph node dissection for colon cancer. RB McBride B Lebwohl DL Hershman AI Neugut, Cancer Epidemiol Biomarkers Prev 2010 19 738 745 10.1158/1055-9965.EPI-09-1086 20200428
39. A Predictive Model for Lymph Node Yield in Colon Cancer Resection Specimens. GM Nash D Row A Weiss J Shia JG Guillem PB Paty M Gonen MR Weiser LK Temple G Fitzmaurice WD Wong, Ann Surg 2010
40. Lymph node retrieval and assessment in stage II colorectal cancer: a population-based study. FC Wright CH Law L Last M Khalifa A Arnaout Z Naseer N Klar S Gallinger AJ Smith, Annals of surgical oncology 2003 10 903 909 10.1245/ASO.2003.01.012 14527909 (Pubitemid 40486855)
41. Clinical significance of colorectal cancer: metastases in lymph nodes < 5 mm in size. MA Rodriguez-Bigas S Maamoun TK Weber RB Penetrante LE Blumenson NJ Petrelli, Annals of surgical oncology 1996 3 124 130 10.1007/BF02305790 8646511 (Pubitemid 126729499)
42. Prognostic significance of cytokeratin-20 reverse transcriptase polymerase chain reaction in lymph nodes of node-negative colorectal cancer patients. R Rosenberg A Hoos J Mueller P Baier D Stricker M Werner H Nekarda JR Siewert, J Clin Oncol 2002 20 1049 1055 10.1200/JCO.20.4.1049 11844829 (Pubitemid 34144594)
43. Cryosurgical ablation and radiofrequency ablation for unresectable hepatic malignant neoplasms: a proposed algorithm. AJ Bilchik TF Wood D Allegra GJ Tsioulias M Chung DM Rose KP Ramming DL Morton, Arch Surg 2000 135 657 662 discussion 662-654 10.1001/archsurg.135.6.657 10843361
44. Lymphatic mapping and focused analysis of sentinel lymph nodes upstage gastrointestinal neoplasms. GJ Tsioulias TF Wood DL Morton AJ Bilchik, Arch Surg 2000 135 926 932 10.1001/archsurg.135.8.926 10922254 (Pubitemid 30625970)
45. Sentinel lymph node mapping in colorectal cancer - a review. S Saha D Nora JH Wong D Weise, The Surgical clinics of North America 2000 80 1811 1819 10.1016/S0039-6109(05)70263-2 11140875 (Pubitemid 32006395)
46. Phase I study on sentinel lymph node mapping in colon cancer: a preliminary report. Y Bendavid JF Latulippe RJ Younan YE Leclerc S Dube F Heyen M Morin R Girard E Bastien J Ferreira M Cerino P Dube, J Surg Oncol 2002 79 81 84 discussion 85 10.1002/jso.10052 11815993 (Pubitemid 34111931)
47. Validation of sentinel node mapping in patients with colon cancer. JC Paramo J Summerall R Poppiti TW Mesko, Ann Surg Oncol 2002 9 550 554 10.1007/BF02573890 12095970 (Pubitemid 34774415)
48. RT-PCR and immunohistochemical evaluation of sentinel lymph nodes after in vivo mapping with Patent Blue V in colon cancer patients. W Kelder A van den Berg J van der Leij W Bleeker AT Tiebosch JK Grond PC Baas JT Plukker, Scandinavian journal of gastroenterology 2006 41 1073 1078 10.1080/ 00365520600554469 16938721
49. Nodal staging score: a tool to assess adequate staging of node-negative colon cancer. M Gonen D Schrag MR Weiser, J Clin Oncol 2009 27 6166 6171 10.1200/JCO.2009.23.7958 19901106
50. Colon cancer clinical practice guidelines in oncology. PF Engstrom AB Benson YJ Chen MA Choti RA Dilawari CA Enke MG Fakih C Fuchs K Kiel JA Knol LA Leong KA Ludwig EW Martin Jr S Rao MW Saif L Saltz JM Skibber AP Venook TJ Yeatman, J Natl Compr Canc Netw 2005 3 468 491 16038639 (Pubitemid 44265422)