-
1
-
-
84860511567
-
Age-related macular degeneration
-
Lim LS, Mitchell P, Seddon JM, Holz FG, Wong TY. Age-related macular degeneration. Lancet. 2012;379:1728-1738.
-
(2012)
Lancet.
, vol.379
, pp. 1728-1738
-
-
Lim, L.S.1
Mitchell, P.2
Seddon, J.M.3
Holz, F.G.4
Wong, T.Y.5
-
4
-
-
84870723704
-
Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration
-
Heier JS, Brown DM, Chong V, et al. Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration. Ophthalmology. 2012;119:2537-2548.
-
(2012)
Ophthalmology.
, vol.119
, pp. 2537-2548
-
-
Heier, J.S.1
Brown, D.M.2
Chong, V.3
-
5
-
-
84863320414
-
Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: Two-year results
-
Martin DF, Maguire MG, Fine SL, et al. Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: two-year results. Ophthalmology. 2012;119: 1388-1398.
-
(2012)
Ophthalmology.
, vol.119
, pp. 1388-1398
-
-
Martin, D.F.1
Maguire, M.G.2
Fine, S.L.3
-
6
-
-
79951525187
-
Systemic and ocular safety of intravitreal anti-VEGF therapies for ocular neovascular disease
-
Tolentino M. Systemic and ocular safety of intravitreal anti-VEGF therapies for ocular neovascular disease. Surv Ophthalmol. 2011;56:95-113.
-
(2011)
Surv Ophthalmol.
, vol.56
, pp. 95-113
-
-
Tolentino, M.1
-
7
-
-
34848817406
-
Non-responders to bevacizumab (Avastin) therapy of choroidal neovascular lesions
-
Lux A, Llacer H, Heussen FM, Joussen AM. Non-responders to bevacizumab (Avastin) therapy of choroidal neovascular lesions. Br J Ophthalmol. 2007;91:1318-1322.
-
(2007)
Br J Ophthalmol.
, vol.91
, pp. 1318-1322
-
-
Lux, A.1
Llacer, H.2
Heussen, F.M.3
Joussen, A.M.4
-
8
-
-
56549111386
-
Is there tachyphylaxis to intravitreal anti-vascular endothelial growth factor pharmacotherapy in age-related macular degeneration?
-
Schaal S, Kaplan HJ, Tezel TH. Is there tachyphylaxis to intravitreal anti-vascular endothelial growth factor pharmacotherapy in age-related macular degeneration? Ophthalmology. 2008;115:2199-2205.
-
(2008)
Ophthalmology.
, vol.115
, pp. 2199-2205
-
-
Schaal, S.1
Kaplan, H.J.2
Tezel, T.H.3
-
9
-
-
67749106387
-
Tachyphylaxis after intravitreal bevacizumab for exudative agerelated macular degeneration
-
Forooghian F, Cukras C, Meyerle CB, Chew EY, Wong WT. Tachyphylaxis after intravitreal bevacizumab for exudative agerelated macular degeneration. Retina. 2009;29:723-731.
-
(2009)
Retina.
, vol.29
, pp. 723-731
-
-
Forooghian, F.1
Cukras, C.2
Meyerle, C.B.3
Chew, E.Y.4
Wong, W.T.5
-
10
-
-
45149087968
-
Effect of bevacizumab on inflammation and proliferation in human choroidal neovascularization
-
Tatar O, Yoeruek E, Szurman P, et al. Effect of bevacizumab on inflammation and proliferation in human choroidal neovascularization. Arch Ophthalmol. 2008;126:782-790.
-
(2008)
Arch Ophthalmol.
, vol.126
, pp. 782-790
-
-
Tatar, O.1
Yoeruek, E.2
Szurman, P.3
-
11
-
-
60749096085
-
Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system
-
Augustin HG, Koh GY, Thurston G, Alitalo K. Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol. 2009;10:165-177.
-
(2009)
Nat Rev Mol Cell Biol.
, vol.10
, pp. 165-177
-
-
Augustin, H.G.1
Koh, G.Y.2
Thurston, G.3
Alitalo, K.4
-
12
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, Holash J. Vascular-specific growth factors and blood vessel formation. Nature. 2000;407:242-248.
-
(2000)
Nature.
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
Rudge, J.S.4
Wiegand, S.J.5
Holash, J.6
-
13
-
-
0034036689
-
Angiopoietin-1 protects the adult vasculature against plasma leakage
-
Thurston G, Rudge JS, Ioffe E, et al. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med. 2000;6: 460-463.
-
(2000)
Nat Med.
, vol.6
, pp. 460-463
-
-
Thurston, G.1
Rudge, J.S.2
Ioffe, E.3
-
14
-
-
22144447473
-
Long-term and sustained COMP-Ang1 induces long-lasting vascular enlargement and enhanced blood flow
-
Cho CH, Kim KE, Byun J, et al. Long-term and sustained COMP-Ang1 induces long-lasting vascular enlargement and enhanced blood flow. Circ Res. 2005;97:86-94.
-
(2005)
Circ Res.
, vol.97
, pp. 86-94
-
-
Cho, C.H.1
Kim, K.E.2
Byun, J.3
-
15
-
-
0036896814
-
Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells
-
Uemura A, Ogawa M, Hirashima M, et al. Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells. J Clin Invest. 2002;110:1619-1628.
-
(2002)
J Clin Invest.
, vol.110
, pp. 1619-1628
-
-
Uemura, A.1
Ogawa, M.2
Hirashima, M.3
-
16
-
-
84884686050
-
Angiopoietin-1 guides directional angiogenesis through integrin alphavbeta5 signaling for recovery of ischemic retinopathy
-
Lee J, Kim KE, Choi DK, et al. Angiopoietin-1 guides directional angiogenesis through integrin alphavbeta5 signaling for recovery of ischemic retinopathy. Sci Transl Med. 2013;5:203ra127.
-
(2013)
Sci Transl Med.
, vol.5
-
-
Lee, J.1
Kim, K.E.2
Choi, D.K.3
-
17
-
-
84871719489
-
Orchestral actions of angiopoietin-1 in vascular regeneration
-
Koh GY. Orchestral actions of angiopoietin-1 in vascular regeneration. Trends Mol Med. 2013;19:31-39.
-
(2013)
Trends Mol Med.
, vol.19
, pp. 31-39
-
-
Koh, G.Y.1
-
18
-
-
0034730784
-
Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions
-
Gamble JR, Drew J, Trezise L, et al. Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions. Circ Res. 2000;87:603-607.
-
(2000)
Circ Res.
, vol.87
, pp. 603-607
-
-
Gamble, J.R.1
Drew, J.2
Trezise, L.3
-
19
-
-
0035860845
-
Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression
-
Kim I, Moon SO, Park SK, Chae SW, Koh GY. Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression. Circ Res. 2001;89:477-479.
-
(2001)
Circ Res.
, vol.89
, pp. 477-479
-
-
Kim, I.1
Moon, S.O.2
Park, S.K.3
Chae, S.W.4
Koh, G.Y.5
-
20
-
-
2642557374
-
Angiopoietin 1 inhibits ocular neovascularization and breakdown of the blood-retinal barrier
-
Nambu H, Nambu R, Oshima Y, et al. Angiopoietin 1 inhibits ocular neovascularization and breakdown of the blood-retinal barrier. Gene Ther. 2004;11:865-873.
-
(2004)
Gene Ther.
, vol.11
, pp. 865-873
-
-
Nambu, H.1
Nambu, R.2
Oshima, Y.3
-
21
-
-
20144374351
-
Angiopoietin 1 prevents retinal detachment in an aggressive model of proliferative retinopathy, but has no effect on established neovascularization
-
Nambu H, Umeda N, Kachi S, et al. Angiopoietin 1 prevents retinal detachment in an aggressive model of proliferative retinopathy, but has no effect on established neovascularization. J Cell Physiol. 2005;204:227-235.
-
(2005)
J Cell Physiol.
, vol.204
, pp. 227-235
-
-
Nambu, H.1
Umeda, N.2
Kachi, S.3
-
22
-
-
84879158849
-
Potential protective effect of angiopoietin-1 on the leakage of rat choroidal neovascularization
-
Wang Y, Bi H, Teng D, et al. Potential protective effect of angiopoietin-1 on the leakage of rat choroidal neovascularization. Saudi Med J. 2013;34:584-590.
-
(2013)
Saudi Med J.
, vol.34
, pp. 584-590
-
-
Wang, Y.1
Bi, H.2
Teng, D.3
-
23
-
-
11144355412
-
Designed angiopoietin-1 variant, COMP-Ang1, protects against radiation-induced endothelial cell apoptosis
-
Cho CH, Kammerer RA, Lee HJ, et al. Designed angiopoietin-1 variant, COMP-Ang1, protects against radiation-induced endothelial cell apoptosis. Proc Natl Acad Sci U S A. 2004;101: 5553-5558.
-
(2004)
Proc Natl Acad Sci U S A.
, vol.101
, pp. 5553-5558
-
-
Cho, C.H.1
Kammerer, R.A.2
Lee, H.J.3
-
24
-
-
61849108712
-
Angiopoietins contribute to lung development by regulating pulmonary vascular network formation
-
Hato T, Kimura Y, Morisada T, et al. Angiopoietins contribute to lung development by regulating pulmonary vascular network formation. Biochem Biophys Res Commun. 2009; 381:218-223.
-
(2009)
Biochem Biophys Res Commun.
, vol.381
, pp. 218-223
-
-
Hato, T.1
Kimura, Y.2
Morisada, T.3
-
25
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet. 1999;21:70-71.
-
(1999)
Nat Genet.
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
26
-
-
0031768434
-
Targeted disruption of the FGF2 gene does not prevent choroidal neovascularization in a murine model
-
Tobe T, Ortega S, Luna JD, et al. Targeted disruption of the FGF2 gene does not prevent choroidal neovascularization in a murine model. Am J Pathol. 1998;153:1641-1646.
-
(1998)
Am J Pathol.
, vol.153
, pp. 1641-1646
-
-
Tobe, T.1
Ortega, S.2
Luna, J.D.3
-
27
-
-
77955534812
-
Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage
-
Koh YJ, Kim HZ, Hwang SI, et al. Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage. Cancer Cell. 2010;18:171-184.
-
(2010)
Cancer Cell.
, vol.18
, pp. 171-184
-
-
Koh, Y.J.1
Kim, H.Z.2
Hwang, S.I.3
-
29
-
-
0037401890
-
VEGF-TRAP(R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier
-
Saishin Y, Takahashi K, Lima e, Silva R, et al. VEGF-TRAP(R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier. J Cell Physiol. 2003; 195:241-248.
-
(2003)
J Cell Physiol.
, vol.195
, pp. 241-248
-
-
Saishin, Y.1
Takahashi, K.2
Lima, E.3
Silva, R.4
-
30
-
-
84863392783
-
Recombinant human angiopoietin-1 ameliorates the expressions of ZO-1, occludin, VE-cadherin, and PKCalpha signaling after focal cerebral ischemia/reperfusion in rats
-
Yu H, Wang P, An P, Xue Y. Recombinant human angiopoietin-1 ameliorates the expressions of ZO-1, occludin, VE-cadherin, and PKCalpha signaling after focal cerebral ischemia/reperfusion in rats. J Mol Neurosci. 2012;46:236-247.
-
(2012)
J Mol Neurosci.
, vol.46
, pp. 236-247
-
-
Yu, H.1
Wang, P.2
An, P.3
Xue, Y.4
-
31
-
-
33750529948
-
VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin
-
Gavard J, Gutkind JS. VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin. Nat Cell Biol. 2006;8:1223-1234.
-
(2006)
Nat Cell Biol.
, vol.8
, pp. 1223-1234
-
-
Gavard, J.1
Gutkind, J.S.2
-
32
-
-
0035021651
-
VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly
-
Wang W, Dentler WL, Borchardt RT. VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly. Am J Physiol Heart Circ Physiol. 2001;280:H434-H440.
-
(2001)
Am J Physiol Heart Circ Physiol.
, vol.280
-
-
Wang, W.1
Dentler, W.L.2
Borchardt, R.T.3
-
33
-
-
68949129005
-
Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability
-
Murakami T, Felinski EA, Antonetti DA. Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem. 2009;284:21036-21046.
-
(2009)
J Biol Chem.
, vol.284
, pp. 21036-21046
-
-
Murakami, T.1
Felinski, E.A.2
Antonetti, D.A.3
-
34
-
-
84884149475
-
VE-cadherin and endothelial adherens junctions: Active guardians of vascular integrity
-
Giannotta M, Trani M, Dejana E. VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity. Dev Cell. 2013;26:441-454.
-
(2013)
Dev Cell.
, vol.26
, pp. 441-454
-
-
Giannotta, M.1
Trani, M.2
Dejana, E.3
-
35
-
-
33847036675
-
In vivo actions of angiopoietins on quiescent and remodeling blood and lymphatic vessels in mouse airways and skin
-
Kim KE, Cho CH, Kim HZ, Baluk P, McDonald DM, Koh GY. In vivo actions of angiopoietins on quiescent and remodeling blood and lymphatic vessels in mouse airways and skin. Arterioscler Thromb Vasc Biol. 2007;27:564-570.
-
(2007)
Arterioscler Thromb Vasc Biol.
, vol.27
, pp. 564-570
-
-
Kim, K.E.1
Cho, C.H.2
Kim, H.Z.3
Baluk, P.4
McDonald, D.M.5
Koh, G.Y.6
-
36
-
-
0042844768
-
Macrophage depletion inhibits experimental choroidal neovascularization
-
Sakurai E, Anand A, Ambati BK, van Rooijen N, Ambati J. Macrophage depletion inhibits experimental choroidal neovascularization. Invest Ophthalmol Vis Sci. 2003;44:3578-3585.
-
(2003)
Invest Ophthalmol Vis Sci.
, vol.44
, pp. 3578-3585
-
-
Sakurai, E.1
Anand, A.2
Ambati, B.K.3
van Rooijen, N.4
Ambati, J.5
-
37
-
-
0142231914
-
Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization
-
Espinosa-Heidmann DG, Caicedo A, Hernandez EP, Csaky KG, Cousins SW. Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization. Invest Ophthalmol Vis Sci. 2003;44:4914-4919.
-
(2003)
Invest Ophthalmol Vis Sci.
, vol.44
, pp. 4914-4919
-
-
Espinosa-Heidmann, D.G.1
Caicedo, A.2
Hernandez, E.P.3
Csaky, K.G.4
Cousins, S.W.5
-
38
-
-
75749145866
-
Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells
-
Gu H, Cui M, Bai Y, et al. Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells. Biochem Biophys Res Commun. 2010;392:178-182.
-
(2010)
Biochem Biophys Res Commun.
, vol.392
, pp. 178-182
-
-
Gu, H.1
Cui, M.2
Bai, Y.3
-
39
-
-
37848998838
-
Angiopoietin-1 prevents VEGFinduced endothelial permeability by sequestering Src through mDia
-
Gavard J, Patel V, Gutkind JS. Angiopoietin-1 prevents VEGFinduced endothelial permeability by sequestering Src through mDia. Dev Cell. 2008;14:25-36.
-
(2008)
Dev Cell.
, vol.14
, pp. 25-36
-
-
Gavard, J.1
Patel, V.2
Gutkind, J.S.3
-
40
-
-
84871954875
-
VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx
-
Ngok SP, Geyer R, Liu M, et al. VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. J Cell Biol. 2012;199:1103-1115.
-
(2012)
J Cell Biol.
, vol.199
, pp. 1103-1115
-
-
Ngok, S.P.1
Geyer, R.2
Liu, M.3
-
41
-
-
0032873955
-
Expressions of angiopoietins and Tie2 in human choroidal neovascular membranes
-
Otani A, Takagi H, Oh H, Koyama S, Matsumura M, Honda Y. Expressions of angiopoietins and Tie2 in human choroidal neovascular membranes. Invest Ophthalmol Vis Sci. 1999;40: 1912-1920.
-
(1999)
Invest Ophthalmol Vis Sci.
, vol.40
, pp. 1912-1920
-
-
Otani, A.1
Takagi, H.2
Oh, H.3
Koyama, S.4
Matsumura, M.5
Honda, Y.6
-
42
-
-
0035009998
-
Angiopoietin-1 upregulation by vascular endothelial growth factor in human retinal pigment epithelial cells
-
Hangai M, Murata T, Miyawaki N, et al. Angiopoietin-1 upregulation by vascular endothelial growth factor in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2001;42:1617-1625.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 1617-1625
-
-
Hangai, M.1
Murata, T.2
Miyawaki, N.3
|