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Volumn 51, Issue 2, 2014, Pages 189-202

Biochemical markers of bone turnover - uses and limitations

Author keywords

Bone disorders; bone turnover markers; clinical studies

Indexed keywords

BONE DISORDERS; BONE TURNOVER MARKERS; CLINICAL STUDIES;

EID: 84898679418     PISSN: 00045632     EISSN: 17581001     Source Type: Journal    
DOI: 10.1177/0004563213515190     Document Type: Review
Times cited : (204)

References (106)
  • 3
    • 0032060217 scopus 로고    scopus 로고
    • Bone remodelling
    • Hill PA.Bone remodelling.Br J Orthod. 1998;25:101-107.
    • (1998) Br J Orthod , vol.25 , pp. 101-107
    • Hill, P.A.1
  • 4
    • 44649152966 scopus 로고    scopus 로고
    • Remodeling and fragility
    • Heaney R.Remodeling and fragility.Osteoporos Int. 2003;14:S12-S15.
    • (2003) Osteoporos Int , vol.14
    • Heaney, R.1
  • 5
    • 3242686322 scopus 로고    scopus 로고
    • Requirements for improving quality in the measurement of bone markers
    • Bernardi D,Zaninotto M,Plebani M.Requirements for improving quality in the measurement of bone markers.Clin Chim Acta. 2004;346:79-86.
    • (2004) Clin Chim Acta , vol.346 , pp. 79-86
    • Bernardi, D.1    Zaninotto, M.2    Plebani, M.3
  • 6
    • 0343069666 scopus 로고
    • Boston, MA: Little Brown & Co
    • Bone biodynamics. Frost HM, ed. Boston, MA: Little Brown & Co.; 1964:315-333.
    • (1964) Bone Biodynamics , pp. 315-333
    • Frost, H.M.1
  • 8
    • 0031405795 scopus 로고    scopus 로고
    • Biochemical markers of bone metabolism: an overview
    • Christenson RH.Biochemical markers of bone metabolism: an overview.Clin Biochem. 1997;30:573-593.
    • (1997) Clin Biochem , vol.30 , pp. 573-593
    • Christenson, R.H.1
  • 9
    • 0021347224 scopus 로고
    • Serum levels of type I and III procollagen fragments in Paget's disease of bone
    • Simon LS,Krane SM,Wortman PD, et al.Serum levels of type I and III procollagen fragments in Paget's disease of bone.J Clin Endocrinol Metab. 1984;58:110-120.
    • (1984) J Clin Endocrinol Metab , vol.58 , pp. 110-120
    • Simon, L.S.1    Krane, S.M.2    Wortman, P.D.3
  • 10
    • 0023488581 scopus 로고
    • Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt AM,Drezner MK,Glorieux FH, et al.Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee.J Bone Miner Res. 1987;2:595-610.
    • (1987) J Bone Miner Res , vol.2 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3
  • 11
    • 59949098895 scopus 로고    scopus 로고
    • Role of serum P1NP measurement for monitoring treatment response in osteoporosis
    • Samoszuk M,Leuther M,Hoyle N.Role of serum P1NP measurement for monitoring treatment response in osteoporosis.Biomark Med. 2008;2:495-508.
    • (2008) Biomark Med , vol.2 , pp. 495-508
    • Samoszuk, M.1    Leuther, M.2    Hoyle, N.3
  • 12
    • 32644474873 scopus 로고    scopus 로고
    • Serum cathepsin K levels of patients with longstanding rheumatoid arthritis: correlation with radiological destruction
    • Skoumal M,Haberhauer G,Kolarz G, et al.Serum cathepsin K levels of patients with longstanding rheumatoid arthritis: correlation with radiological destruction.Arthritis Res Ther. 2005;7:R65-R70.
    • (2005) Arthritis Res Ther , vol.7
    • Skoumal, M.1    Haberhauer, G.2    Kolarz, G.3
  • 13
    • 0025149128 scopus 로고
    • Circulating C-terminal propeptide of type I procollagen is cleared mainly via the mannose receptor in liver endothelial cells
    • Smedsrod B,Melkko J,Risteli L, et al.Circulating C-terminal propeptide of type I procollagen is cleared mainly via the mannose receptor in liver endothelial cells.Biochem J. 1990;271:345-350.
    • (1990) Biochem J , vol.271 , pp. 345-350
    • Smedsrod, B.1    Melkko, J.2    Risteli, L.3
  • 14
    • 0023431110 scopus 로고
    • Procollagen type I carboxy-terminal extension peptide in serum as a marker of collagen biosynthesis in bone. Correlation with iliac bone formation rates and comparison with total alkaline phosphatase
    • Parfitt AM,Simon LS,Villanueva AR, et al.Procollagen type I carboxy-terminal extension peptide in serum as a marker of collagen biosynthesis in bone. Correlation with iliac bone formation rates and comparison with total alkaline phosphatase.J Bone Miner Res. 1987;2:427-436.
    • (1987) J Bone Miner Res , vol.2 , pp. 427-436
    • Parfitt, A.M.1    Simon, L.S.2    Villanueva, A.R.3
  • 15
    • 0034748181 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover
    • Swaminathan R.Biochemical markers of bone turnover.Clin Chim Acta. 2001;313:95-105.
    • (2001) Clin Chim Acta , vol.313 , pp. 95-105
    • Swaminathan, R.1
  • 16
    • 38749150609 scopus 로고    scopus 로고
    • Evaluation of a fully automated serum assay for total N-terminal propeptide of type I collagen in postmenopausal osteoporosis
    • Garnero P,Vergnaud P,Hoyle N.Evaluation of a fully automated serum assay for total N-terminal propeptide of type I collagen in postmenopausal osteoporosis.Clin Chem. 2008;54:188-196.
    • (2008) Clin Chem , vol.54 , pp. 188-196
    • Garnero, P.1    Vergnaud, P.2    Hoyle, N.3
  • 17
    • 77952479638 scopus 로고    scopus 로고
    • Teriparatide is safe and effectively increases bone biomarkers in institutionalized individuals with osteoporosis
    • Ryder KM,Tanner SB,Carbone L, et al.Teriparatide is safe and effectively increases bone biomarkers in institutionalized individuals with osteoporosis.J Bone Miner Metab. 2010;28:233-239.
    • (2010) J Bone Miner Metab , vol.28 , pp. 233-239
    • Ryder, K.M.1    Tanner, S.B.2    Carbone, L.3
  • 18
    • 38349165577 scopus 로고    scopus 로고
    • Short-term response of bone turnover to low-dose oral contraceptives in exercising women with hypothalamic amenorrhea
    • Vescovi JD,VanHeest JL,De Souza MJ.Short-term response of bone turnover to low-dose oral contraceptives in exercising women with hypothalamic amenorrhea.Contraception. 2008;77:97-104.
    • (2008) Contraception , vol.77 , pp. 97-104
    • Vescovi, J.D.1    VanHeest, J.L.2    de Souza, M.J.3
  • 19
    • 67349103852 scopus 로고    scopus 로고
    • Bone turnover markers: understanding their value in clinical trials and clinical practice
    • Civitelli R,Armamento-Villareal R,Napoli N.Bone turnover markers: understanding their value in clinical trials and clinical practice.Osteoporos Int. 2009;20:843-851.
    • (2009) Osteoporos Int , vol.20 , pp. 843-851
    • Civitelli, R.1    Armamento-Villareal, R.2    Napoli, N.3
  • 20
    • 0034526072 scopus 로고    scopus 로고
    • The use of biochemical markers of bone turnover in osteoporosis. Committee of Scientific Advisors of the International Osteoporosis Foundation
    • Delmas PD,Eastell R,Garnero P, et al.The use of biochemical markers of bone turnover in osteoporosis. Committee of Scientific Advisors of the International Osteoporosis Foundation.Osteoporos Int. 2000;11:S2-S17.
    • (2000) Osteoporos Int , vol.11
    • Delmas, P.D.1    Eastell, R.2    Garnero, P.3
  • 21
    • 33847633816 scopus 로고    scopus 로고
    • Analysis of human bone alkaline phosphatase isoforms: comparison of isoelectric focusing and ion-exchange high-performance liquid chromatography
    • Sharp CA,Linder C,Magnusson P.Analysis of human bone alkaline phosphatase isoforms: comparison of isoelectric focusing and ion-exchange high-performance liquid chromatography.Clin Chim Acta. 2007;379:105-112.
    • (2007) Clin Chim Acta , vol.379 , pp. 105-112
    • Sharp, C.A.1    Linder, C.2    Magnusson, P.3
  • 22
    • 0027454352 scopus 로고
    • Assessment of the serum levels of bone alkaline phosphatase with a new immunoradiometric assay in patients with metabolic bone disease
    • Garnero P,Delmas PD.Assessment of the serum levels of bone alkaline phosphatase with a new immunoradiometric assay in patients with metabolic bone disease.J Clin Endocrinol Metab. 1993;77:1046-1053.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1046-1053
    • Garnero, P.1    Delmas, P.D.2
  • 23
    • 0029845152 scopus 로고    scopus 로고
    • Comparison of total and bone-specific alkaline phosphatase in patients with nonskeletal disorder or metabolic bone diseases
    • Woitge HW,Seibel MJ,Ziegler R.Comparison of total and bone-specific alkaline phosphatase in patients with nonskeletal disorder or metabolic bone diseases.Clin Chem. 1996;42:1796-1804.
    • (1996) Clin Chem , vol.42 , pp. 1796-1804
    • Woitge, H.W.1    Seibel, M.J.2    Ziegler, R.3
  • 24
    • 0035127621 scopus 로고    scopus 로고
    • Effect of vitamin K and/or D on undercarboxylated and intact osteocalcin in osteoporotic patients with vertebral or hip fractures
    • Takahashi M,Naitou K,Ohishi T, et al.Effect of vitamin K and/or D on undercarboxylated and intact osteocalcin in osteoporotic patients with vertebral or hip fractures.Clin Endocrinol (Oxf). 2001;54:219-224.
    • (2001) Clin Endocrinol (Oxf) , vol.54 , pp. 219-224
    • Takahashi, M.1    Naitou, K.2    Ohishi, T.3
  • 25
    • 0024120485 scopus 로고
    • Serum and urinary markers of bone remodeling: assessment of bone turnover
    • Epstein S.Serum and urinary markers of bone remodeling: assessment of bone turnover.Endocr Rev. 1988;9:438-448.
    • (1988) Endocr Rev , vol.9 , pp. 438-448
    • Epstein, S.1
  • 26
    • 0025835098 scopus 로고
    • Osteocalcin: diagnostic methods and clinical applications
    • Power MJ,Fottrell PF.Osteocalcin: diagnostic methods and clinical applications.Crit Rev Clin Lab Sci. 1991;28:287-335.
    • (1991) Crit Rev Clin Lab Sci , vol.28 , pp. 287-335
    • Power, M.J.1    Fottrell, P.F.2
  • 27
    • 0025881829 scopus 로고
    • Osteocalcin concentrations in plasma prepared with different anticoagulants
    • Power MJ,O'Dwyer B,Breen E, et al.Osteocalcin concentrations in plasma prepared with different anticoagulants.Clin Chem. 1991;37:281-284.
    • (1991) Clin Chem , vol.37 , pp. 281-284
    • Power, M.J.1    O'Dwyer, B.2    Breen, E.3
  • 28
    • 0033041177 scopus 로고    scopus 로고
    • Molecular markers of bone and cartilage metabolism
    • Woitge HW,Seibel MJ.Molecular markers of bone and cartilage metabolism.Curr Opin Rheumatol. 1999;11:218-225.
    • (1999) Curr Opin Rheumatol , vol.11 , pp. 218-225
    • Woitge, H.W.1    Seibel, M.J.2
  • 30
    • 25444449013 scopus 로고    scopus 로고
    • Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover
    • Nenonen A,Cheng S,Ivaska KK, et al.Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover.J Bone Miner Res. 2005;20:1804-1812.
    • (2005) J Bone Miner Res , vol.20 , pp. 1804-1812
    • Nenonen, A.1    Cheng, S.2    Ivaska, K.K.3
  • 31
    • 0034047217 scopus 로고    scopus 로고
    • Tartrate-resistant acid phosphatase 5b: a novel serum marker of bone resorption
    • Halleen JM,Alatalo SL,Suominen H, et al.Tartrate-resistant acid phosphatase 5b: a novel serum marker of bone resorption.J Bone Miner Res. 2000;15:1337-1345.
    • (2000) J Bone Miner Res , vol.15 , pp. 1337-1345
    • Halleen, J.M.1    Alatalo, S.L.2    Suominen, H.3
  • 32
    • 0942300651 scopus 로고    scopus 로고
    • Clinical performance of immunoreactive tartrate-resistant acid phosphatase isoform 5b as a marker of bone resorption
    • Hannon RA,Clowes JA,Eagleton AC, et al.Clinical performance of immunoreactive tartrate-resistant acid phosphatase isoform 5b as a marker of bone resorption.Bone. 2004;34:187-194.
    • (2004) Bone , vol.34 , pp. 187-194
    • Hannon, R.A.1    Clowes, J.A.2    Eagleton, A.C.3
  • 33
    • 0029828170 scopus 로고    scopus 로고
    • The measurement of pyridinium crosslinks: a methodological overview
    • James IT,Walne AJ,Perrett D.The measurement of pyridinium crosslinks: a methodological overview.Ann Clin Biochem. 1996;33 (part 5): 397-420.
    • (1996) Ann Clin Biochem , vol.33 , Issue.PART 5 , pp. 397-420
    • James, I.T.1    Walne, A.J.2    Perrett, D.3
  • 34
    • 0028927464 scopus 로고
    • Determination of pyridinoline and deoxypyridinoline in urine, with special attention to retaining their stability
    • Gerrits MI,Thijssen JH,van Rijn HJ.Determination of pyridinoline and deoxypyridinoline in urine, with special attention to retaining their stability.Clin Chem. 1995;41:571-574.
    • (1995) Clin Chem , vol.41 , pp. 571-574
    • Gerrits, M.I.1    Thijssen, J.H.2    van Rijn, H.J.3
  • 35
    • 0030883716 scopus 로고    scopus 로고
    • Serum levels of pyridinium crosslinks in postmenopausal women and in Paget's disease of bone
    • Sinigaglia L,Varenna M,Binelli L, et al.Serum levels of pyridinium crosslinks in postmenopausal women and in Paget's disease of bone.Calcif Tissue Int. 1997;61:279-284.
    • (1997) Calcif Tissue Int , vol.61 , pp. 279-284
    • Sinigaglia, L.1    Varenna, M.2    Binelli, L.3
  • 36
    • 0036233579 scopus 로고    scopus 로고
    • Type I collagen racemization and isomerization and the risk of fracture in postmenopausal women: the OFELY prospective study
    • Garnero P,Cloos P,Sornay-Rendu E, et al.Type I collagen racemization and isomerization and the risk of fracture in postmenopausal women: the OFELY prospective study.J Bone Miner Res. 2002;17:826-833.
    • (2002) J Bone Miner Res , vol.17 , pp. 826-833
    • Garnero, P.1    Cloos, P.2    Sornay-Rendu, E.3
  • 37
    • 0033962103 scopus 로고    scopus 로고
    • Markers of bone turnover for the management of patients with bone metastases from prostate cancer
    • Garnero P,Buchs N,Zekri J, et al.Markers of bone turnover for the management of patients with bone metastases from prostate cancer.Br J Cancer. 2000;82:858-864.
    • (2000) Br J Cancer , vol.82 , pp. 858-864
    • Garnero, P.1    Buchs, N.2    Zekri, J.3
  • 38
    • 33746934212 scopus 로고    scopus 로고
    • Biochemical response to bisphosphonate therapy in pagetic patients with skull involvement
    • Peris P,Alvarez L,Vidal S, et al.Biochemical response to bisphosphonate therapy in pagetic patients with skull involvement.Calcif Tissue Int. 2006;79:22-26.
    • (2006) Calcif Tissue Int , vol.79 , pp. 22-26
    • Peris, P.1    Alvarez, L.2    Vidal, S.3
  • 39
    • 0034105693 scopus 로고    scopus 로고
    • Circadian variation in serum crosslaps concentration is reduced in fasting individuals
    • Christgau S.Circadian variation in serum crosslaps concentration is reduced in fasting individuals.Clin Chem. 2000;46:431-431.
    • (2000) Clin Chem , vol.46 , pp. 431
    • Christgau, S.1
  • 40
    • 9844258321 scopus 로고    scopus 로고
    • Comparison of analytical performance and biological variability of three bone resorption assays
    • Ju HS,Leung S,Brown B, et al.Comparison of analytical performance and biological variability of three bone resorption assays.Clin Chem. 1997;43:1570-1576.
    • (1997) Clin Chem , vol.43 , pp. 1570-1576
    • Ju, H.S.1    Leung, S.2    Brown, B.3
  • 41
    • 0035063272 scopus 로고    scopus 로고
    • Evaluation of a fully automated serum assay for C-terminal cross-linking telopeptide of type I collagen in osteoporosis
    • Garnero P,Borel O,Delmas PD.Evaluation of a fully automated serum assay for C-terminal cross-linking telopeptide of type I collagen in osteoporosis.Clin Chem. 2001;47:694-702.
    • (2001) Clin Chem , vol.47 , pp. 694-702
    • Garnero, P.1    Borel, O.2    Delmas, P.D.3
  • 42
    • 17144446565 scopus 로고    scopus 로고
    • Urine products of bone breakdown as markers of bone resorption and clinical usefulness of urinary hydroxyproline: an overview
    • Simsek B,Karacaer O,Karaca I.Urine products of bone breakdown as markers of bone resorption and clinical usefulness of urinary hydroxyproline: an overview.Chin Med J (Engl). 2004;117:291-295.
    • (2004) Chin Med J (Engl) , vol.117 , pp. 291-295
    • Simsek, B.1    Karacaer, O.2    Karaca, I.3
  • 43
    • 33646827389 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover: part I: biochemistry and variability
    • Seibel MJ.Biochemical markers of bone turnover: part I: biochemistry and variability.Clin Biochem Rev. 2005;26:97-122.
    • (2005) Clin Biochem Rev , vol.26 , pp. 97-122
    • Seibel, M.J.1
  • 44
    • 0029815692 scopus 로고    scopus 로고
    • Serum immunoreactive bone sialoprotein as a new marker of bone turnover in metabolic and malignant bone disease
    • Seibel MJ,Woitge HW,Pecherstorfer M, et al.Serum immunoreactive bone sialoprotein as a new marker of bone turnover in metabolic and malignant bone disease.J Clin Endocrinol Metab. 1996;81:3289-3294.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3289-3294
    • Seibel, M.J.1    Woitge, H.W.2    Pecherstorfer, M.3
  • 45
    • 0033663910 scopus 로고    scopus 로고
    • Bone sialoprotein is a specific biochemical marker of bone metabolism in postmenopausal women: a randomized 1-year study
    • Stork S,Stork C,Angerer P, et al.Bone sialoprotein is a specific biochemical marker of bone metabolism in postmenopausal women: a randomized 1-year study.Osteoporos Int. 2000;11:790-796.
    • (2000) Osteoporos Int , vol.11 , pp. 790-796
    • Stork, S.1    Stork, C.2    Angerer, P.3
  • 46
    • 79953146730 scopus 로고    scopus 로고
    • Odanacatib, a new drug for the treatment of osteoporosis: review of the results in postmenopausal women
    • Perez-Castrillon JL,Pinacho F,De LD, et al.Odanacatib, a new drug for the treatment of osteoporosis: review of the results in postmenopausal women.J Osteoporos. 2010;2010:.
    • (2010) J Osteoporos , vol.2010
    • Perez-Castrillon, J.L.1    Pinacho, F.2    De, L.D.3
  • 47
    • 22144485121 scopus 로고    scopus 로고
    • Soluble cathepsin K: a novel marker for the prediction of nontraumatic fractures?
    • Holzer G,Noske H,Lang T, et al.Soluble cathepsin K: a novel marker for the prediction of nontraumatic fractures?.J Lab Clin Med. 2005;146:13-17.
    • (2005) J Lab Clin Med , vol.146 , pp. 13-17
    • Holzer, G.1    Noske, H.2    Lang, T.3
  • 48
    • 0009660825 scopus 로고    scopus 로고
    • Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro
    • Yasuda H,Shima N,Nakagawa N, et al.Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro.Endocrinology. 1998;139:1329-1337.
    • (1998) Endocrinology , vol.139 , pp. 1329-1337
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3
  • 49
    • 27744599521 scopus 로고    scopus 로고
    • Circulating osteoprotegerin and receptor activator for nuclear factor kappaB ligand: clinical utility in metabolic bone disease assessment
    • Rogers A,Eastell R.Circulating osteoprotegerin and receptor activator for nuclear factor kappaB ligand: clinical utility in metabolic bone disease assessment.J Clin Endocrinol Metab. 2005;90:6323-6331.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6323-6331
    • Rogers, A.1    Eastell, R.2
  • 50
    • 0031720576 scopus 로고    scopus 로고
    • Urinary markers of bone turnover in healthy children and adolescents: age-related changes and effect of puberty
    • Mora S,Prinster C,Proverbio MC, et al.Urinary markers of bone turnover in healthy children and adolescents: age-related changes and effect of puberty.Calcif Tissue Int. 1998;63:369-374.
    • (1998) Calcif Tissue Int , vol.63 , pp. 369-374
    • Mora, S.1    Prinster, C.2    Proverbio, M.C.3
  • 51
    • 0033014787 scopus 로고    scopus 로고
    • Age-related changes in bone turnover in men
    • Fatayerji D,Eastell R.Age-related changes in bone turnover in men.J Bone Miner Res. 1999;14:1203-1210.
    • (1999) J Bone Miner Res , vol.14 , pp. 1203-1210
    • Fatayerji, D.1    Eastell, R.2
  • 52
    • 0028849265 scopus 로고
    • Urinary excretion of type I collagen crosslinked N-telopeptides in healthy Japanese adults: age- and sex-related changes and reference limits
    • Sone T,Miyake M,Takeda N, et al.Urinary excretion of type I collagen crosslinked N-telopeptides in healthy Japanese adults: age- and sex-related changes and reference limits.Bone. 1995;17:335-339.
    • (1995) Bone , vol.17 , pp. 335-339
    • Sone, T.1    Miyake, M.2    Takeda, N.3
  • 53
    • 0030019056 scopus 로고    scopus 로고
    • A comparison of the urinary excretion of bone resorptive products in white and black children
    • Pratt JH,Manatunga AK,Peacock M.A comparison of the urinary excretion of bone resorptive products in white and black children.J Lab Clin Med. 1996;127:67-70.
    • (1996) J Lab Clin Med , vol.127 , pp. 67-70
    • Pratt, J.H.1    Manatunga, A.K.2    Peacock, M.3
  • 54
    • 0034519794 scopus 로고    scopus 로고
    • Preanalytical variability of biochemical markers of bone turnover
    • Hannon R,Eastell R.Preanalytical variability of biochemical markers of bone turnover.Osteoporos Int. 2000;11:S30-S44.
    • (2000) Osteoporos Int , vol.11
    • Hannon, R.1    Eastell, R.2
  • 55
    • 0033962846 scopus 로고    scopus 로고
    • The effect of pregnancy on bone density and bone turnover
    • Naylor KE,Iqbal P,Fledelius C, et al.The effect of pregnancy on bone density and bone turnover.J Bone Miner Res. 2000;15:129-137.
    • (2000) J Bone Miner Res , vol.15 , pp. 129-137
    • Naylor, K.E.1    Iqbal, P.2    Fledelius, C.3
  • 56
    • 0032721289 scopus 로고    scopus 로고
    • Changes in bone mass and bone turnover following distal forearm fracture
    • Ingle BM,Hay SM,Bottjer HM, et al.Changes in bone mass and bone turnover following distal forearm fracture.Osteoporos Int. 1999;10:399-407.
    • (1999) Osteoporos Int , vol.10 , pp. 399-407
    • Ingle, B.M.1    Hay, S.M.2    Bottjer, H.M.3
  • 57
    • 33645238236 scopus 로고    scopus 로고
    • Changes in bone mass and bone turnover following tibial shaft fracture
    • Veitch SW,Findlay SC,Hamer AJ, et al.Changes in bone mass and bone turnover following tibial shaft fracture.Osteoporos Int. 2006;17:364-372.
    • (2006) Osteoporos Int , vol.17 , pp. 364-372
    • Veitch, S.W.1    Findlay, S.C.2    Hamer, A.J.3
  • 58
    • 0031718368 scopus 로고    scopus 로고
    • The effects of twelve weeks of bed rest on bone histology, biochemical markers of bone turnover, and calcium homeostasis in eleven normal subjects
    • Zerwekh JE,Ruml LA,Gottschalk F, et al.The effects of twelve weeks of bed rest on bone histology, biochemical markers of bone turnover, and calcium homeostasis in eleven normal subjects.J Bone Miner Res. 1998;13:1594-1601.
    • (1998) J Bone Miner Res , vol.13 , pp. 1594-1601
    • Zerwekh, J.E.1    Ruml, L.A.2    Gottschalk, F.3
  • 59
    • 0032853805 scopus 로고    scopus 로고
    • Bone mineral in pre- and postmenopausal women with insulin-dependent and non-insulin-dependent diabetes mellitus
    • Christensen JO,Svendsen OL.Bone mineral in pre- and postmenopausal women with insulin-dependent and non-insulin-dependent diabetes mellitus.Osteoporos Int. 1999;10:307-311.
    • (1999) Osteoporos Int , vol.10 , pp. 307-311
    • Christensen, J.O.1    Svendsen, O.L.2
  • 60
    • 0032917449 scopus 로고    scopus 로고
    • Bone density, vitamin D status, and disordered bone remodeling in end-stage chronic liver disease
    • Crosbie OM,Freaney R,McKenna MJ, et al.Bone density, vitamin D status, and disordered bone remodeling in end-stage chronic liver disease.Calcif Tissue Int. 1999;64:295-300.
    • (1999) Calcif Tissue Int , vol.64 , pp. 295-300
    • Crosbie, O.M.1    Freaney, R.2    McKenna, M.J.3
  • 61
    • 0029092738 scopus 로고
    • Urinary biochemical markers for bone resorption during the menstrual cycle
    • Gorai I,Chaki O,Nakayama M, et al.Urinary biochemical markers for bone resorption during the menstrual cycle.Calcif Tissue Int. 1995;57:100-104.
    • (1995) Calcif Tissue Int , vol.57 , pp. 100-104
    • Gorai, I.1    Chaki, O.2    Nakayama, M.3
  • 62
    • 0025265595 scopus 로고
    • Changes in biochemical markers of osteoblastic activity during the menstrual cycle
    • Nielsen HK,Brixen K,Bouillon R, et al.Changes in biochemical markers of osteoblastic activity during the menstrual cycle.J Clin Endocrinol Metab. 1990;70:1431-1437.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 1431-1437
    • Nielsen, H.K.1    Brixen, K.2    Bouillon, R.3
  • 63
    • 0031737568 scopus 로고    scopus 로고
    • Seasonal variation of biochemical indexes of bone turnover: results of a population-based study
    • Woitge HW,Scheidt-Nave C,Kissling C, et al.Seasonal variation of biochemical indexes of bone turnover: results of a population-based study.J Clin Endocrinol Metab. 1998;83:68-75.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 68-75
    • Woitge, H.W.1    Scheidt-Nave, C.2    Kissling, C.3
  • 64
    • 0027465359 scopus 로고
    • Physiological variations in the urinary excretion of pyridinium crosslinks of collagen
    • McLaren AM,Isdale AH,Whiting PH, et al.Physiological variations in the urinary excretion of pyridinium crosslinks of collagen.Br J Rheumatol. 1993;32:307-312.
    • (1993) Br J Rheumatol , vol.32 , pp. 307-312
    • McLaren, A.M.1    Isdale, A.H.2    Whiting, P.H.3
  • 65
    • 0036443371 scopus 로고    scopus 로고
    • Biological variability of biochemical markers of bone turnover in healthy women
    • Takahashi M,Kawana K,Nagano A.Biological variability of biochemical markers of bone turnover in healthy women.Endocr Res. 2002;28:257-264.
    • (2002) Endocr Res , vol.28 , pp. 257-264
    • Takahashi, M.1    Kawana, K.2    Nagano, A.3
  • 67
    • 0034926030 scopus 로고    scopus 로고
    • Interlaboratory variation of biochemical markers of bone turnover
    • Seibel MJ,Lang M,Geilenkeuser WJ.Interlaboratory variation of biochemical markers of bone turnover.Clin Chem. 2001;47:1443-1450.
    • (2001) Clin Chem , vol.47 , pp. 1443-1450
    • Seibel, M.J.1    Lang, M.2    Geilenkeuser, W.J.3
  • 69
    • 65849281252 scopus 로고    scopus 로고
    • [Epidemiology of osteoporosis]
    • Chapurlat R.[Epidemiology of osteoporosis].J Soc Biol. 2008;202:251-255.
    • (2008) J Soc Biol , vol.202 , pp. 251-255
    • Chapurlat, R.1
  • 71
    • 84859441811 scopus 로고    scopus 로고
    • Does osteoporosis therapy invalidate FRAX for fracture prediction?
    • Leslie WD,Lix LM,Johansson H, et al.Does osteoporosis therapy invalidate FRAX for fracture prediction?.J Bone Miner Res. 2012;27:1243-1251.
    • (2012) J Bone Miner Res , vol.27 , pp. 1243-1251
    • Leslie, W.D.1    Lix, L.M.2    Johansson, H.3
  • 72
    • 0023214452 scopus 로고
    • Prediction of rapid bone loss in postmenopausal women
    • Christiansen C.Prediction of rapid bone loss in postmenopausal women.Lancet. 1987;May:1105-1108.
    • (1987) Lancet , vol.May , pp. 1105-1108
    • Christiansen, C.1
  • 73
    • 0029928837 scopus 로고    scopus 로고
    • Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis
    • Garnero P,Sornay-Rendu E,Chapuy MC, et al.Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis.J Bone Miner Res. 1996;11:337-349.
    • (1996) J Bone Miner Res , vol.11 , pp. 337-349
    • Garnero, P.1    Sornay-Rendu, E.2    Chapuy, M.C.3
  • 74
    • 0343517092 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: the OFELY study
    • Garnero P,Sornay-Rendu E,Claustrat B, et al.Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: the OFELY study.J Bone Miner Res. 2000;15:1526-1536.
    • (2000) J Bone Miner Res , vol.15 , pp. 1526-1536
    • Garnero, P.1    Sornay-Rendu, E.2    Claustrat, B.3
  • 75
    • 0031156595 scopus 로고    scopus 로고
    • The predictive value of biochemical markers of bone turnover for bone mineral density in early postmenopausal women treated with hormone replacement or calcium supplementation
    • Rosen CJ,Chesnut CH,Mallinak NJ.The predictive value of biochemical markers of bone turnover for bone mineral density in early postmenopausal women treated with hormone replacement or calcium supplementation.J Clin Endocrinol Metab. 1997;82:1904-1910.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1904-1910
    • Rosen, C.J.1    Chesnut, C.H.2    Mallinak, N.J.3
  • 76
    • 73849146589 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover, hip bone loss, and fracture in older men: the MrOS study
    • Bauer DC,Garnero P,Harrison SL, et al.Biochemical markers of bone turnover, hip bone loss, and fracture in older men: the MrOS study.J Bone Miner Res. 2009;24:2032-2038.
    • (2009) J Bone Miner Res , vol.24 , pp. 2032-2038
    • Bauer, D.C.1    Garnero, P.2    Harrison, S.L.3
  • 77
    • 0023214452 scopus 로고
    • Prediction of rapid bone loss in postmenopausal women
    • Christiansen C,Riis BJ,Rodbro P.Prediction of rapid bone loss in postmenopausal women.Lancet. 1987;1:1105-1108.
    • (1987) Lancet , vol.1 , pp. 1105-1108
    • Christiansen, C.1    Riis, B.J.2    Rodbro, P.3
  • 78
    • 10144251796 scopus 로고    scopus 로고
    • Markers of bone resorption predict hip fracture in elderly women: the EPIDOS prospective study
    • Garnero P,Hausherr E,Chapuy MC, et al.Markers of bone resorption predict hip fracture in elderly women: the EPIDOS prospective study.J Bone Miner Res. 1996;11:1531-1538.
    • (1996) J Bone Miner Res , vol.11 , pp. 1531-1538
    • Garnero, P.1    Hausherr, E.2    Chapuy, M.C.3
  • 79
    • 25444438208 scopus 로고    scopus 로고
    • Identification of osteopenic women at high risk of fracture: the OFELY study
    • Sornay-Rendu E,Munoz F,Garnero P, et al.Identification of osteopenic women at high risk of fracture: the OFELY study.J Bone Miner Res. 2005;20:1813-1819.
    • (2005) J Bone Miner Res , vol.20 , pp. 1813-1819
    • Sornay-Rendu, E.1    Munoz, F.2    Garnero, P.3
  • 80
    • 15344343455 scopus 로고    scopus 로고
    • Bone resorption and osteoporotic fractures in elderly men: the Dubbo osteoporosis epidemiology study
    • Meier C,Nguyen TV,Center JR, et al.Bone resorption and osteoporotic fractures in elderly men: the Dubbo osteoporosis epidemiology study.J Bone Miner Res. 2005;20:579-587.
    • (2005) J Bone Miner Res , vol.20 , pp. 579-587
    • Meier, C.1    Nguyen, T.V.2    Center, J.R.3
  • 81
    • 0036133366 scopus 로고    scopus 로고
    • Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density
    • Riggs BL,Melton LJ.Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density.J Bone Miner Res. 2002;17:11-14.
    • (2002) J Bone Miner Res , vol.17 , pp. 11-14
    • Riggs, B.L.1    Melton, L.J.2
  • 82
    • 0036133350 scopus 로고    scopus 로고
    • Relationships between bone mineral density and incident vertebral fracture risk with raloxifene therapy
    • Sarkar S,Mitlak BH,Wong M, et al.Relationships between bone mineral density and incident vertebral fracture risk with raloxifene therapy.J Bone Miner Res. 2002;17:1-10.
    • (2002) J Bone Miner Res , vol.17 , pp. 1-10
    • Sarkar, S.1    Mitlak, B.H.2    Wong, M.3
  • 83
    • 33144489593 scopus 로고    scopus 로고
    • Pretreatment levels of bone turnover and the antifracture efficacy of alendronate: the fracture intervention trial
    • Bauer DC,Garnero P,Hochberg MC, et al.Pretreatment levels of bone turnover and the antifracture efficacy of alendronate: the fracture intervention trial.J Bone Miner Res. 2006;21:292-299.
    • (2006) J Bone Miner Res , vol.21 , pp. 292-299
    • Bauer, D.C.1    Garnero, P.2    Hochberg, M.C.3
  • 84
    • 0141625900 scopus 로고    scopus 로고
    • Relationship of early changes in bone resorption to the reduction in fracture risk with risedronate
    • Eastell R,Barton I,Hannon RA, et al.Relationship of early changes in bone resorption to the reduction in fracture risk with risedronate.J Bone Miner Res. 2003;18:1051-1056.
    • (2003) J Bone Miner Res , vol.18 , pp. 1051-1056
    • Eastell, R.1    Barton, I.2    Hannon, R.A.3
  • 85
    • 34247866550 scopus 로고    scopus 로고
    • Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis
    • Black DM,Delmas PD,Eastell R, et al.Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis.N Engl J Med. 2007;356:1809-1822.
    • (2007) N Engl J Med , vol.356 , pp. 1809-1822
    • Black, D.M.1    Delmas, P.D.2    Eastell, R.3
  • 86
    • 69049083492 scopus 로고    scopus 로고
    • Denosumab for prevention of fractures in postmenopausal women with osteoporosis
    • Cummings SR,San MJ,McClung MR, et al.Denosumab for prevention of fractures in postmenopausal women with osteoporosis.N Engl J Med. 2009;361:756-765.
    • (2009) N Engl J Med , vol.361 , pp. 756-765
    • Cummings, S.R.1    San, M.J.2    McClung, M.R.3
  • 87
    • 70350230386 scopus 로고    scopus 로고
    • Rapid and robust response of biochemical markers of bone formation to teriparatide therapy
    • Glover SJ,Eastell R,McCloskey EV, et al.Rapid and robust response of biochemical markers of bone formation to teriparatide therapy.Bone. 2009;45:1053-1058.
    • (2009) Bone , vol.45 , pp. 1053-1058
    • Glover, S.J.1    Eastell, R.2    McCloskey, E.V.3
  • 88
    • 0004851872 scopus 로고    scopus 로고
    • Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group
    • Black DM,Cummings SR,Karpf DB, et al.Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group.Lancet. 1996;348:1535-1541.
    • (1996) Lancet , vol.348 , pp. 1535-1541
    • Black, D.M.1    Cummings, S.R.2    Karpf, D.B.3
  • 89
    • 0036828449 scopus 로고    scopus 로고
    • Two-year results of once-weekly administration of alendronate 70 mg for the treatment of postmenopausal osteoporosis
    • Rizzoli R,Greenspan SL,Bone G, et al.Two-year results of once-weekly administration of alendronate 70 mg for the treatment of postmenopausal osteoporosis.J Bone Miner Res. 2002;17:1988-1996.
    • (2002) J Bone Miner Res , vol.17 , pp. 1988-1996
    • Rizzoli, R.1    Greenspan, S.L.2    Bone, G.3
  • 90
    • 1642401432 scopus 로고    scopus 로고
    • The impact of monitoring on adherence and persistence with antiresorptive treatment for postmenopausal osteoporosis: a randomized controlled trial
    • Clowes JA,Peel NF,Eastell R.The impact of monitoring on adherence and persistence with antiresorptive treatment for postmenopausal osteoporosis: a randomized controlled trial.J Clin Endocrinol Metab. 2004;89:1117-1123.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1117-1123
    • Clowes, J.A.1    Peel, N.F.2    Eastell, R.3
  • 91
    • 34147128320 scopus 로고    scopus 로고
    • Effect of monitoring bone turnover markers on persistence with risedronate treatment of postmenopausal osteoporosis
    • Delmas PD,Vrijens B,Eastell R, et al.Effect of monitoring bone turnover markers on persistence with risedronate treatment of postmenopausal osteoporosis.J Clin Endocrinol Metab. 2007;92:1296-1304.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1296-1304
    • Delmas, P.D.1    Vrijens, B.2    Eastell, R.3
  • 92
    • 84898687203 scopus 로고    scopus 로고
    • Paget's Association, (accessed 21 November 2013)
    • Paget's Association. Paget's disease-the facts, http://www.paget.org.uk/factsbooklet/factsbooklet.pdf (2010, accessed 21 November 2013).
    • (2010) Paget's disease-the facts
  • 93
    • 0034748394 scopus 로고    scopus 로고
    • Usefulness of biochemical markers of bone turnover in assessing response to the treatment of Paget's disease
    • Alvarez L,Guanabens N,Peris P, et al.Usefulness of biochemical markers of bone turnover in assessing response to the treatment of Paget's disease.Bone. 2001;29:447-452.
    • (2001) Bone , vol.29 , pp. 447-452
    • Alvarez, L.1    Guanabens, N.2    Peris, P.3
  • 95
    • 0034023810 scopus 로고    scopus 로고
    • Components of biological variation of biochemical markers of bone turnover in Paget's bone disease
    • Alvarez L,Ricos C,Peris P, et al.Components of biological variation of biochemical markers of bone turnover in Paget's bone disease.Bone. 2000;26:571-576.
    • (2000) Bone , vol.26 , pp. 571-576
    • Alvarez, L.1    Ricos, C.2    Peris, P.3
  • 96
    • 3242885274 scopus 로고    scopus 로고
    • Long-term biochemical response after bisphosphonate therapy in Paget's disease of bone. Proposed intervals for monitoring treatment
    • Alvarez L,Peris P,Guanabens N, et al.Long-term biochemical response after bisphosphonate therapy in Paget's disease of bone. Proposed intervals for monitoring treatment.Rheumatology (Oxford). 2004;43:869-874.
    • (2004) Rheumatology (Oxford) , vol.43 , pp. 869-874
    • Alvarez, L.1    Peris, P.2    Guanabens, N.3
  • 97
    • 0036755909 scopus 로고    scopus 로고
    • Guidelines on the management of Paget's disease of bone
    • Selby PL,Davie MW,Ralston SH, et al.Guidelines on the management of Paget's disease of bone.Bone. 2002;31:366-373.
    • (2002) Bone , vol.31 , pp. 366-373
    • Selby, P.L.1    Davie, M.W.2    Ralston, S.H.3
  • 98
    • 33750726077 scopus 로고    scopus 로고
    • Clinical features of metastatic bone disease and risk of skeletal morbidity
    • Coleman RE.Clinical features of metastatic bone disease and risk of skeletal morbidity.Clin Cancer Res. 2006;12(20 part 2):6243s-6249s.
    • (2006) Clin Cancer Res , vol.12 , Issue.20 PART 2
    • Coleman, R.E.1
  • 99
    • 77956832136 scopus 로고    scopus 로고
    • Evolving role of bone biomarkers in castration-resistant prostate cancer
    • Brown JE,Sim S.Evolving role of bone biomarkers in castration-resistant prostate cancer.Neoplasia. 2010;12:685-696.
    • (2010) Neoplasia , vol.12 , pp. 685-696
    • Brown, J.E.1    Sim, S.2
  • 100
    • 33847762912 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover in the clinical development of drugs for osteoporosis and metastatic bone disease: potential uses and pitfalls
    • Cremers S,Garnero P.Biochemical markers of bone turnover in the clinical development of drugs for osteoporosis and metastatic bone disease: potential uses and pitfalls.Drugs. 2006;66:2031-2058.
    • (2006) Drugs , vol.66 , pp. 2031-2058
    • Cremers, S.1    Garnero, P.2
  • 101
    • 33646237342 scopus 로고    scopus 로고
    • Bone markers and current laboratory assays
    • Hannon RA,Eastell R.Bone markers and current laboratory assays.Cancer Treat Rev. 2006;32:7-14.
    • (2006) Cancer Treat Rev , vol.32 , pp. 7-14
    • Hannon, R.A.1    Eastell, R.2
  • 102
    • 0035022942 scopus 로고    scopus 로고
    • Markers of bone turnover in prostate cancer
    • Garnero P.Markers of bone turnover in prostate cancer.Cancer Treat Rev. 2001;27:187-192.
    • (2001) Cancer Treat Rev , vol.27 , pp. 187-192
    • Garnero, P.1
  • 103
    • 33645457788 scopus 로고    scopus 로고
    • The relative use of eight collagenous and noncollagenous markers for diagnosis of skeletal metastases in breast, prostate, or lung cancer patients
    • Leeming DJ,Koizumi M,Byrjalsen I, et al.The relative use of eight collagenous and noncollagenous markers for diagnosis of skeletal metastases in breast, prostate, or lung cancer patients.Cancer Epidemiol Biomarkers Prev. 2006;15:32-38.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 32-38
    • Leeming, D.J.1    Koizumi, M.2    Byrjalsen, I.3
  • 104
    • 27644471852 scopus 로고    scopus 로고
    • Clinical use of markers of bone turnover in metastatic bone disease
    • Seibel MJ.Clinical use of markers of bone turnover in metastatic bone disease.Nat Clin Pract Oncol. 2005;2:504-517.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. 504-517
    • Seibel, M.J.1
  • 105
    • 47149118386 scopus 로고    scopus 로고
    • Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid
    • Lipton A,Cook R,Saad F, et al.Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid.Cancer. 2008;113:193-201.
    • (2008) Cancer , vol.113 , pp. 193-201
    • Lipton, A.1    Cook, R.2    Saad, F.3
  • 106
    • 78651493109 scopus 로고    scopus 로고
    • Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards
    • Vasikaran S, et al.Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards.Osteoporos Int. 2011;22:391-420.
    • (2011) Osteoporos Int , vol.22 , pp. 391-420
    • Vasikaran, S.1


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