Profilin-1 Promotes the Development of Hypertension-induced Artery Remodeling

Journal of Histochemistry and Cytochemistry

Volumn 62, Issue 4, 2014, Pages 298-310

  Wang, Yan ^a,b   Zhang, Jun ^a,b   Gao, Haiqing ^a,b   Zhao, Shaohua ^a,b   Ji, Xiang ^a,b   Liu, Xiangju ^a,b   You, Beian ^a   Li, Xiao ^a   Qiu, Jie ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b Shandong Provincial Key Laboratory of Cardiovascular Proteomics   (China)

Author keywords

adenovirus vector; hypertension; profilin 1; SHR; vascular remodeling

Indexed keywords

ADENOVIRUS VECTOR; HYPERTENSION; PROFILIN-1; SHR; VASCULAR REMODELING;

ANIMALS; AORTA, THORACIC; BODY WEIGHT; FIBROSIS; HYPERTENSION; MALE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEROXYNITROUS ACID; PROFILINS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SPECIES SPECIFICITY;

EID: 84898676758     PISSN: 00221554     EISSN: 15515044     Source Type: Journal    
DOI: 10.1369/0022155414520978     Document Type: Article

References (43)

1. Bapat S,Verkleij A,Post J.Peroxynitrite activates mitogen-activated protein kinase (MAPK) via a MEK-independent pathway: a role for protein kinase C.FEBS Lett. 2001;499:21-26.
2. Beckman JS,Beckman TW,Chen J,Marshall PA,Freeman BA.Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.Proc Natl Acad Sci U S A. 1990;87:1620-1624.
3. Bhat NR,Feinstein DL,Shen Q,Bhat AN.p38 MAPK-mediated transcriptional activation of inducible nitric-oxide synthase in glial cells. Roles of nuclear factors, nuclear factor kappa B, cAMP response element-binding protein, CCAAT/enhancer-binding protein-beta, and activating transcription factor-2.J Biol Chem. 2002;277:29584-29592.
4. Buttery L,Springall D,Chester A,Evans T,Standfield N,Parums D,Yacoub M,Polak J.Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite.Lab Invest. 1996;75:77-85.
5. Chen Q,Chen T,Li W,Zhang W,Zhu J,Li Y,Huang Y,Shen Y,Yu C.Mycoepoxydiene inhibits lipopolysaccharide-induced inflammatory responses through the of TRAF6 polyubiquitination.PlOS One. 2012;7:e44890.
6. Chou T-C,Yen M-H,Li C-Y,Ding Y-A.Alterations of nitric oxide synthase expression with aging and hypertension in rats.Hypertension. 1998;31:643-648.
7. Clerk A,Michael A,Sugden PH.Stimulation of the p38 Mitogen-activated Protein Kinase Pathway in Neonatal Rat Ventricular Myocytes by the G Protein-coupled Receptor Agonists, Endothelin-1 and Phenylephrine: A Role in Cardiac Myocyte Hypertrophy?.J Cell Biol. 1998;142:523-535.
8. Enslen H,Raingeaud J,Davis RJ.Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6.J Biol Chem. 1998;273:1741-1748.
9. Epstein FH,Gibbons GH,Dzau VJ.The emerging concept of vascular remodeling.New Engl J Med. 1994;330:1431-1438.
10. Fornieri C,Quaglino D,Mori G.Role of the extracellular matrix in age-related modifications of the rat aorta. Ultrastructural, morphometric, and enzymatic evaluations.A Arterioscler Thromb Vasc Biol. 1992;12:1008-1016.
11. Gragasin FS,Xu Y,Arenas IA,Kainth N,Davidge ST.Estrogen reduces angiotensin II-induced nitric oxide synthase and NAD (P) H oxidase expression in endothelial cells.Arterioscler Thromb Vasc Biol. 2003;23:38-44.
12. Han J,Jiang Y,Li Z,Kravchenko V,Ulevitch R.Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation.Nature. 1997;386:296-299.
13. Hassona MD,Elnakish MT,Abouelnaga ZA,Alhaj M,Wani AA,Hassanain H.The effect of selective antihypertensive drugs on the vascular remodeling-associated hypertension: insights from a profilin1 transgenic mouse model.J Cardiovasc Pharm. 2011;57:550-558.
14. Hayashi K,Naiki T.Adaptation and remodeling of vascular wall; biomechanical response to hypertension.J Mech Behav Biomed Mater. 2009;2:3-19.
15. Herce-Pagliai C,Kotecha S,Shuker DE.Analytical methods for 3-nitrotyrosine as a marker of exposure to reactive nitrogen species: A review.Nitric Oxide. 1998;2:324-336.
16. Hong HJ,Loh SH,Yen MH.Suppression of the development of hypertension by the inhibitor of inducible nitric oxide synthase.Brit J Pharmacol. 2000;131:631-637.
17. Jin H-Y,Song B,Oudit GY,Davidge ST,Yu H-M,Jiang Y-Y,Gao P-J,Zhu D-L,Ning G,Kassiri Z.ACE2 deficiency enhances angiotensin II-mediated aortic profilin-1 expression, inflammation and peroxynitrite production.PLOS One. 2012;7:e38502.
18. Kim HR,Graceffa P,Ferron F,Gallant C,Boczkowska M,Dominguez R,Morgan KG.Actin polymerization in differentiated vascular smooth muscle cells requires vasodilator-stimulated phosphoprotein.Am J Physiol Cell Physiol. 2010;298:C559-C571.
19. Krum H,Gilbert RE.Novel therapies blocking the renin-angiotensin-aldosterone system in the management of hypertension and related disorders.J Hypertens. 2007;25:25-35.
20. Moustafa-Bayoumi M,Alhaj MA,El-Sayed O,Wisel S,Chotani MA,Abouelnaga ZA,Hassona MD,Rigatto K,Morris M,Nuovo G.Vascular hypertrophy and hypertension caused by transgenic overexpression of profilin 1.J Biol Chem. 2007;282:37632-37639.
21. Mungrue IN,Gros R,You X,Pirani A,Azad A,Csont T,Schulz R,Butany J,Stewart DJ,Husain M.Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death.J Clin Invest. 2002;109:735-743.
22. Oudit GY,Kassiri Z,Patel MP,Chappell M,Butany J,Backx PH,Tsushima RG,Scholey JW,Khokha R,Penninger JM.Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.Cardiovasc Res. 2007;75:29-39.
23. Park HS,Kniep AC,Smith SC,Robie SM,Smith EC,Yu SY,Mackenzie JW,Scott GE,Boyd CD.Changes in vascular extracellular matrix accumulation reflect phenotypic differences between the arterial wall of pigeons resistant and susceptible to the development of spontaneous atherosclerosis.Connect Tissue Res. 1990;25:67-76.
24. Pauletto P,Rattazzi M.Inflammation and hypertension: the search for a link.Nephrol Dial Transplant. 2006;21:850-853.
25. Pietri P,Vyssoulis G,Vlachopoulos C,Zervoudaki A,Gialernios T,Aznaouridis K,Stefanadis C.Relationship between low-grade inflammation and arterial stiffness in patients with essential hypertension.J Hypertens. 2006;24:2231-2238.
26. Radomski A,Sawicki G,Olson DM,Radomski MW.The role of nitric oxide and metalloproteinases in the pathogenesis of hyperoxia-induced lung injury in newborn rats.Brit J Pharmacol. 1998;125:1455-1462.
27. Romeo GR,Moulton KS,Kazlauskas A.Attenuated Expression of Profilin-1 Confers Protection From Atherosclerosis in the LDL Receptor-Null Mouse.Circ Res. 2007;101:357-367.
28. Safar M,Chamiot-Clerc P,Dagher G,Renaud JF.Pulse pressure, endothelium function, and arterial stiffness in spontaneously hypertensive rats.Hypertension. 2001;38:1416-1421.
29. Safar ME,Levy BI,Struijker-Boudier H.Current perspectives on arterial stiffness and pulse pressure in hypertension and cardiovascular diseases.Circulation. 2003;107:2864-2869.
30. Shekhonin BV,Domogatsky SP,Muzykantov VR,Idelson GL,Rukosuev VS.Distribution of type I, III, IV and V collagen in normal and atherosclerotic human arterial wall: immunomorphological characteristics.Coll Relat Res. 1985;5:355-368.
31. Steed MM,Tyagi N,Sen U,Schuschke DA,Joshua IG,Tyagi SC.Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS-/-, and iNOS-/- mice.Am J Physiol Lung Cell Mol Physiol. 2010;299:L301-L311.
32. Sugden PH,Fuller SJ.Regulation of protein turnover in skeletal and cardiac muscle.Biochem J. 1991;273:21.
33. Vaziri ND,Ni Z,Oveisi F.Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats.Hypertension. 1998;31:1248-1254.
34. Wang Y,Huang S,Sah VP,Ross J,Brown JH,Han J,Chien KR.Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family.J Biol Chem. 1998;273:2161-2168.
35. Wolinsky H.Long-term effects of hypertension on the rat aortic wall and their relation to concurrent aging changes: morphological and chemical studies.Circ Res. 1972;30:301-309.
36. Wu CC,Hong HJ,Chou TC,Ding YA,Yen MH.Evidence for inducible nitric oxide synthase in spontaneously hypertensive rats.Biochem Biophys Res Commun. 1996;228:459-466.
37. Xue C,Johns RA.Upregulation of nitric oxide synthase correlates temporally with onset of pulmonary vascular remodeling in the hypoxic rat.Hypertension. 1996;28:743-753.
38. Yang C,Patel K,Harding P,Sorokin A,Glass WF.Regulation of TGF-β1/MAPK-mediated PAI-1 gene expression by the actin cytoskeleton in human mesangial cells.Exp Cell Res. 2007;313:1240-1250.
39. Yi L,Jin X,Chen CY,Fu YJ,Zhang T,Chang H,Zhou Y,Zhu JD,Zhang QY,Mi MT.Chemical structures of 4-oxo-flavonoids in relation to inhibition of oxidized low-density lipoprotein (LDL)-induced vascular endothelial dysfunction.Int J Mol Sci. 2011;12:5471-5489.
40. Zen K,Irie H,Doue T,Takamiya M,Yamano T,Sawada T,Azuma A,Matsubara H.Analysis of circulating apoptosis mediators and proinflammatory cytokines in patients with idiopathic hypertrophic cardiomyopathy.Int Heart J. 2005;46:231-244.
41. Zhang P,Wang YZ,Kagan E,Bonner JC.Peroxynitrite targets the epidermal growth factor receptor, Raf-1, and MEK independently to activate MAPK.J Biol Chem. 2000;275:22479-22486.
42. Zhao SH,Qiu J,Wang Y,Ji X,Liu XJ,You BA,Sheng YP,Li X,Gao HQ.Profilin-1 promotes the development of hypertension-induced cardiac hypertrophy.J Hypertens. 2013;31:576-586.
43. Zhong JC,Ye JY,Jin HY,Yu X,Yu HM,Zhu DL,Gao PJ,Huang DY,Shuster M,Loibner H.Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression.Regul Pept. 2011;166:90-97.